propranolol has been researched along with Diabetes Mellitus, Type 2 in 23 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of one month's treatment with each of nifedipine, verapamil, diltiazem, propranolol and placebo, given in random order, on fasting plasma glucose, haemoglobin Alc, serum fructosamine, immunoreactive insulin, cholesterol, and triglyceride were studied in a group of 19 patients with hypertension and non-insulin dependent diabetes mellitus." | 5.06 | The effects of verapamil, diltiazem, nifedipine and propranolol on metabolic control in hypertensives with non-insulin dependent diabetes mellitus. ( Chellingsworth, MC; Kendall, MJ; Pasi, J; Singh, BM; Wright, AD, 1989) |
| "Amlodipine and ramipril were added to their previous antihypertensive treatment for 12 weeks." | 2.72 | Urinary TGF-beta1 reduction related to a decrease of systolic blood pressure in patients with type 2 diabetes and clinical diabetic nephropathy. ( Bertoluci, MC; Oliveira, FR; Schmid, H; Schmidt, A; Thomazelli, FC; Uebel, D, 2006) |
| "Beta blockers used for the treatment of hypertension may be associated with increased risk for new-onset diabetes mellitus (DM)." | 2.44 | A meta-analysis of 94,492 patients with hypertension treated with beta blockers to determine the risk of new-onset diabetes mellitus. ( Bangalore, S; Grossman, E; Messerli, FH; Parkar, S, 2007) |
| "Type 2 diabetes is becoming very common and is closely linked to physical inactivity and obesity." | 2.41 | Beta-blockers and diabetes: the bad guys come good. ( Cruickshank, JM, 2002) |
| "The propranolol group was treated with propranolol ointment and the control group was treated with propranolol matrix cream to cover the wound surface." | 1.51 | Propranolol regulates ERK1/2 signaling pathway and promotes chronic wound healing in diabetic rats. ( Chang, F; Chang, X; Li, S; Xue, XD, 2019) |
| " Dose-response curves with epinephrine from lean mice were best fit to a two-component model comprised of 23% high affinity (K(act) = 1." | 1.29 | Impaired expression and functional activity of the beta 3- and beta 1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice. ( Collins, S; Daniel, KW; Gettys, TW; Ramkumar, V; Rohlfs, EM; Taylor, IL, 1994) |
| "Of 15 patients with clinical diabetic autonomic neuropathy, SPR wave forms were bizarre or absent in 5 patients compared with 18 of 121 patients' without clinical autonomic neuropathy (chi 2 = 3." | 1.28 | Validation and evaluation of test for sympathetic cholinergic function in diabetes mellitus. ( Best, JD; Kirsner, RL; Pestell, RG, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (21.74) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, F | 1 |
| Yang, F | 1 |
| Liang, Y | 1 |
| Li, L | 1 |
| Xia, Y | 1 |
| Jiang, F | 1 |
| Liu, W | 1 |
| Qi, Y | 1 |
| Chowdhury, SR | 1 |
| Xie, D | 1 |
| Fu, L | 1 |
| Lin, H | 1 |
| Sharabi, K | 1 |
| Lin, L | 1 |
| Ruiz, C | 1 |
| Zhu, D | 1 |
| Cameron, MD | 1 |
| Novick, SJ | 1 |
| Griffin, PR | 1 |
| Puigserver, P | 1 |
| Kamenecka, TM | 1 |
| Gales, L | 1 |
| Forsea, L | 1 |
| Mitrea, D | 1 |
| Stefanica, I | 1 |
| Stanculescu, I | 1 |
| Mitrica, R | 1 |
| Georgescu, M | 1 |
| Trifanescu, O | 1 |
| Anghel, R | 1 |
| Serbanescu, L | 1 |
| Vukotic, R | 1 |
| Raimondi, F | 1 |
| Brodosi, L | 1 |
| Vitale, G | 1 |
| Petroni, ML | 1 |
| Marchesini, G | 1 |
| Andreone, P | 1 |
| Chang, X | 1 |
| Li, S | 1 |
| Xue, XD | 1 |
| Chang, F | 1 |
| Li, H | 1 |
| Kem, DC | 1 |
| Reim, S | 1 |
| Khan, M | 1 |
| Vanderlinde-Wood, M | 1 |
| Zillner, C | 1 |
| Collier, D | 1 |
| Liles, C | 1 |
| Hill, MA | 1 |
| Cunningham, MW | 1 |
| Aston, CE | 1 |
| Yu, X | 1 |
| Mirbolooki, MR | 1 |
| Constantinescu, CC | 1 |
| Pan, ML | 1 |
| Mukherjee, J | 1 |
| Cruickshank, JM | 1 |
| Bertoluci, MC | 1 |
| Uebel, D | 1 |
| Schmidt, A | 1 |
| Thomazelli, FC | 1 |
| Oliveira, FR | 1 |
| Schmid, H | 1 |
| Garrido, A | 1 |
| Márquez, JL | 1 |
| Iglesias, A | 1 |
| Peiró, J | 1 |
| Grilo, I | 1 |
| Garzón, M | 1 |
| van der Wouden, EJ | 1 |
| Westerveld, BD | 1 |
| Bangalore, S | 1 |
| Parkar, S | 1 |
| Grossman, E | 1 |
| Messerli, FH | 1 |
| Gray, RS | 1 |
| Borsey, DQ | 1 |
| Irvine, WJ | 1 |
| Duncan, LJ | 1 |
| Clarke, BF | 1 |
| Collins, S | 1 |
| Daniel, KW | 1 |
| Rohlfs, EM | 1 |
| Ramkumar, V | 1 |
| Taylor, IL | 1 |
| Gettys, TW | 1 |
| Marfella, R | 1 |
| Giugliano, D | 1 |
| di Maro, G | 1 |
| Acampora, R | 1 |
| Giunta, R | 1 |
| D'Onofrio, F | 1 |
| Oida, E | 1 |
| Kannagi, T | 1 |
| Moritani, T | 1 |
| Yamori, Y | 1 |
| Getty, L | 1 |
| Panteleon, AE | 1 |
| Mittelman, SD | 1 |
| Dea, MK | 1 |
| Bergman, RN | 1 |
| Lewis, HM | 1 |
| Kendall, MJ | 2 |
| Wright, AD | 2 |
| Bratty, JR | 1 |
| Maxwell, S | 1 |
| Pestell, RG | 1 |
| Kirsner, RL | 1 |
| Best, JD | 1 |
| Chellingsworth, MC | 1 |
| Singh, BM | 1 |
| Pasi, J | 1 |
| Dornhorst, A | 1 |
| Powell, SH | 1 |
| Pensky, J | 1 |
| Broadstone, VL | 1 |
| Pfeifer, MA | 1 |
| Bajaj, V | 1 |
| Stagner, JI | 1 |
| Samols, E | 1 |
| Ravussin, E | 1 |
| Bogardus, C | 1 |
| Schwartz, RS | 1 |
| Robbins, DC | 1 |
| Wolfe, RR | 1 |
| Horton, ES | 1 |
| Danforth, E | 1 |
| Sims, EA | 1 |
3 reviews available for propranolol and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Antidiabetics, Anthelmintics, Statins, and Beta-Blockers as Co-Adjuvant Drugs in Cancer Therapy.
Topics: Adenosine Monophosphate; Adrenergic beta-Antagonists; Anthelmintics; Anti-Bacterial Agents; Antihype | 2022 |
Beta-blockers and diabetes: the bad guys come good.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Bisoprolol; Coronary Disease; Diabet | 2002 |
A meta-analysis of 94,492 patients with hypertension treated with beta blockers to determine the risk of new-onset diabetes mellitus.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Blood Glucose; Body Mass Index; Diab | 2007 |
5 trials available for propranolol and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Agonistic autoantibodies as vasodilators in orthostatic hypotension: a new mechanism.
Topics: Adult; Aged; Animals; Arterioles; Atropine; Autoantibodies; Comorbidity; Diabetes Mellitus, Type 2; | 2012 |
Urinary TGF-beta1 reduction related to a decrease of systolic blood pressure in patients with type 2 diabetes and clinical diabetic nephropathy.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Gluco | 2006 |
A comparison of the metabolic effects of flosequinan and propranolol in patients with non-insulin-dependent diabetes mellitus.
Topics: Adult; Aged; Analysis of Variance; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Double- | 1991 |
The effects of verapamil, diltiazem, nifedipine and propranolol on metabolic control in hypertensives with non-insulin dependent diabetes mellitus.
Topics: Aged; Blood Glucose; Blood Pressure; Cholesterol; Diabetes Mellitus, Type 2; Diltiazem; Female; Fruc | 1989 |
Aggravation by propranolol of hyperglycaemic effect of hydrochlorothiazide in type II diabetics without alteration of insulin secretion.
Topics: Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Synergism; Drug Thera | 1985 |
15 other studies available for propranolol and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Investigation of stereoisomeric bisarylethenesulfonic acid esters for discovering potent and selective PTP1B inhibitors.
Topics: Animals; Antigens, CD; Cell Membrane Permeability; Diabetes Mellitus, Type 2; Esters; Glucose; Human | 2019 |
Structure-Activity Relationship and Biological Investigation of SR18292 (
Topics: Adipocytes, Brown; Animals; Diabetes Mellitus, Type 2; Glucagon; Gluconeogenesis; Hepatocytes; Hypog | 2021 |
The Effect of Liraglutide on β-Blockade for Preventing Variceal Bleeding: A Case Series.
Topics: Adrenergic beta-Antagonists; Aged; Diabetes Mellitus, Type 2; Drug Interactions; Esophageal and Gast | 2020 |
Propranolol regulates ERK1/2 signaling pathway and promotes chronic wound healing in diabetic rats.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Body Weight; Diabetes Mellitus, Exper | 2019 |
Targeting presynaptic norepinephrine transporter in brown adipose tissue: a novel imaging approach and potential treatment for diabetes and obesity.
Topics: Adipose Tissue, Brown; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Atomoxeti | 2013 |
[Hemorrhage due to peristomal ectopic varices: an infrequent complication of portal hypertension].
Topics: Cecal Neoplasms; Colonic Neoplasms; Diabetes Mellitus, Type 2; Duodenal Ulcer; Gastrointestinal Hemo | 2006 |
A patient with diabetes mellitus and recurrent peristomal bleeding.
Topics: Aged; Antihypertensive Agents; Colostomy; Diabetes Mellitus, Type 2; Diagnosis, Differential; Electr | 2006 |
Non-insulin-treated ICA positive and negative diabetics are equally insulin resistant.
Topics: Adult; Antibodies; Autoantibodies; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 1983 |
Impaired expression and functional activity of the beta 3- and beta 1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice.
Topics: Adenylyl Cyclases; Adipose Tissue; Adipose Tissue, Brown; Adrenergic beta-Agonists; Adrenergic beta- | 1994 |
The squatting test. A useful tool to assess both parasympathetic and sympathetic involvement of the cardiovascular autonomic neuropathy in diabetes.
Topics: Adult; Age Factors; Aged; Atropine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic N | 1994 |
Diabetic alteration of cardiac vago-sympathetic modulation assessed with tone-entropy analysis.
Topics: Adult; Aged; Aging; Atropine; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 2; Electrocar | 1999 |
Rapid oscillations in omental lipolysis are independent of changing insulin levels in vivo.
Topics: Activity Cycles; Adrenergic beta-Antagonists; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dog | 2000 |
Validation and evaluation of test for sympathetic cholinergic function in diabetes mellitus.
Topics: Adult; Age Factors; Aged; Atropine; Autonomic Nervous System; Diabetes Mellitus; Diabetes Mellitus, | 1991 |
Alpha-adrenergic blockade improves glucose-potentiated insulin secretion in non-insulin-dependent diabetes mellitus.
Topics: Adrenergic alpha-Antagonists; Adult; Arginine; Blood Glucose; Catecholamines; Diabetes Mellitus, Typ | 1987 |
Glucose-induced thermogenesis and insulin resistance in man.
Topics: Adult; Basal Metabolism; Body Temperature Regulation; Body Weight; Diabetes Mellitus; Diabetes Melli | 1985 |