propranolol has been researched along with Diabetes Mellitus, Type 1 in 37 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The insulin resistance is due to beta-adrenergic stimulation and can be prevented by propranolol." | 2.66 | Insulin resistance in type 1 (insulin-dependent) diabetes following hypoglycaemia--evidence for the importance of beta-adrenergic stimulation. ( Attvall, S; Fowelin, J; Lager, I; Smith, U; von Schenck, H, 1987) |
| "Of 15 patients with clinical diabetic autonomic neuropathy, SPR wave forms were bizarre or absent in 5 patients compared with 18 of 121 patients' without clinical autonomic neuropathy (chi 2 = 3." | 1.28 | Validation and evaluation of test for sympathetic cholinergic function in diabetes mellitus. ( Best, JD; Kirsner, RL; Pestell, RG, 1991) |
| "Diabetic nephropathy is the dominant cause of hypertension in insulin-dependent diabetics, and long-term rigid antihypertensive treatment inhibits the progression of nephropathy, probably even when there is renal insufficiency." | 1.28 | The effect of antihypertensive treatment on kidney function in insulin-dependent (type I) diabetics with renal failure. ( Conde, N; Gums, G; Heinke, P; Schulz, B; Strese, J; Zander, E; Zander, G, 1990) |
| "However, in IDDM with blunted plasma glucagon responses, postnadir plasma glucose recovery was further decreased by propranolol (14 +/- 0." | 1.27 | The adrenergic contribution to glucose counterregulation in type I diabetes mellitus. Dependency on A-cell function and mediation through beta 2-adrenergic receptors. ( Angeletti, G; Bolli, G; Brunetti, P; Compagnucci, P; De Cosmo, S; De Feo, P; Gerich, JE; Motolese, M; Perriello, G; Santeusanio, F, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (62.16) | 18.7374 |
| 1990's | 10 (27.03) | 18.2507 |
| 2000's | 2 (5.41) | 29.6817 |
| 2010's | 1 (2.70) | 24.3611 |
| 2020's | 1 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, P | 1 |
| Macdonald, TL | 1 |
| Chen, M | 1 |
| Nadler, JL | 1 |
| Cardinez, N | 1 |
| Bakhsh, A | 1 |
| Perkins, BA | 1 |
| Kose, S | 1 |
| Gozaydin, A | 1 |
| Akkoclu, G | 1 |
| Ece, G | 1 |
| Lager, I | 2 |
| Ostman, J | 1 |
| De Feo, P | 1 |
| Bolli, G | 1 |
| Perriello, G | 1 |
| De Cosmo, S | 1 |
| Compagnucci, P | 1 |
| Angeletti, G | 1 |
| Santeusanio, F | 1 |
| Gerich, JE | 3 |
| Motolese, M | 1 |
| Brunetti, P | 1 |
| Simonson, DC | 2 |
| Koivisto, V | 1 |
| Sherwin, RS | 2 |
| Ferrannini, E | 1 |
| Hendler, R | 1 |
| Juhlin-Dannfelt, A | 1 |
| DeFronzo, RA | 2 |
| Gray, RS | 1 |
| Borsey, DQ | 1 |
| Irvine, WJ | 1 |
| Duncan, LJ | 1 |
| Clarke, BF | 1 |
| Shamoon, H | 2 |
| Sherwin, R | 1 |
| Jacob, R | 1 |
| Marfella, R | 1 |
| Giugliano, D | 1 |
| di Maro, G | 1 |
| Acampora, R | 1 |
| Giunta, R | 1 |
| D'Onofrio, F | 1 |
| Bolinder, J | 1 |
| Sjöberg, S | 1 |
| Arner, P | 1 |
| Cooper, JW | 1 |
| Chalon, S | 1 |
| Berlin, I | 1 |
| Sachon, C | 1 |
| Bosquet, F | 2 |
| Grimaldi, A | 2 |
| Sigal, RJ | 1 |
| Fisher, SJ | 1 |
| Halter, JB | 2 |
| Vranic, M | 1 |
| Marliss, EB | 1 |
| Gallego, M | 1 |
| Casis, E | 1 |
| Izquierdo, MJ | 1 |
| Casis, O | 1 |
| Saiki, S | 1 |
| Lorenzi, M | 1 |
| Tsalikian, E | 1 |
| Karam, JH | 1 |
| Sperling, MA | 1 |
| Voina, S | 1 |
| Benn, JJ | 1 |
| Brown, PM | 1 |
| Beckwith, LJ | 1 |
| Farebrother, M | 1 |
| Sönksen, PH | 1 |
| Hirsch, IB | 1 |
| Boyle, PJ | 1 |
| Craft, S | 1 |
| Cryer, PE | 2 |
| Pestell, RG | 1 |
| Kirsner, RL | 1 |
| Best, JD | 1 |
| Diem, P | 1 |
| Redmon, JB | 1 |
| Abid, M | 1 |
| Moran, A | 1 |
| Sutherland, DE | 1 |
| Robertson, RP | 1 |
| Zander, E | 1 |
| Conde, N | 1 |
| Heinke, P | 1 |
| Zander, G | 1 |
| Strese, J | 1 |
| Gums, G | 1 |
| Schulz, B | 1 |
| Succi, E | 1 |
| Albanesi Filho, FM | 1 |
| Gomes, MB | 1 |
| Gomes Filho, JB | 1 |
| Attvall, S | 1 |
| Fowelin, J | 1 |
| von Schenck, H | 1 |
| Smith, U | 1 |
| Krone, W | 1 |
| Naegele, H | 1 |
| Behnke, B | 1 |
| Greten, H | 1 |
| Campbell, PJ | 1 |
| Bolli, GB | 1 |
| McClure, AD | 1 |
| Beylot, M | 1 |
| Sautot, G | 1 |
| Dechaud, H | 1 |
| Cohen, R | 1 |
| Riou, JP | 1 |
| Serusclat, P | 1 |
| Mornex, R | 1 |
| Castellino, P | 1 |
| Kotler, MN | 1 |
| Berman, L | 1 |
| Rubenstein, AH | 1 |
| Hansen, AP | 1 |
| Loggie, JM | 1 |
| Van Maanen, EF | 1 |
| Lundbaek, K | 1 |
| Avruskin, TW | 1 |
| Tang, SC | 1 |
| Juan, CS | 1 |
3 reviews available for propranolol and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
beta-adrenergic blockade and diabetes mellitus. A review.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; D | 1983 |
[Blood glucose counter-regulation].
Topics: Adrenergic beta-Antagonists; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids; Glu | 1985 |
The autonomic nervous system and some aspects of the use of autonomic drugs in children. II.
Topics: Adrenergic beta-Antagonists; Aortic Valve Stenosis; Asthma; Autonomic Agents; Bronchitis; Cardiomyop | 1972 |
3 trials available for propranolol and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Propranolol in hypoglycaemia unawareness.
Topics: Adrenergic beta-Antagonists; Adult; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Humans; | 1999 |
Insulin resistance in type 1 (insulin-dependent) diabetes following hypoglycaemia--evidence for the importance of beta-adrenergic stimulation.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Heart Rate; Humans; Hyperglycemia; Hypoglyc | 1987 |
The effect of adrenergic receptor blockade on the exercise-induced serum growth hormone rise in normals and juvenile diabetics.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Glucose; Clinica | 1971 |
31 other studies available for propranolol and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Synthesis and biological evaluation of lisofylline (LSF) analogs as a potential treatment for Type 1 diabetes.
Topics: Animals; Apoptosis; Cell Line; Chemoprevention; Cytokines; Diabetes Mellitus, Type 1; Drug Evaluatio | 2006 |
Propranolol-induced Pancreatitis After Treatment for Graves' Disease in an Adult With Type 1 Diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Graves Disease; Humans; Pancreatitis; Propranolol | 2023 |
Chronic hepatitis B with type I diabetes mellitus and autoimmune thyroiditis development during interferon alpha therapy.
Topics: Adrenergic beta-Antagonists; Adult; Antiviral Agents; Diabetes Mellitus, Type 1; Hepatitis B, Chroni | 2012 |
Adrenergic blockade and hypoglycaemia.
Topics: Adrenergic beta-Antagonists; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Glucag | 1983 |
The adrenergic contribution to glucose counterregulation in type I diabetes mellitus. Dependency on A-cell function and mediation through beta 2-adrenergic receptors.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Hemodynamics; Humans; Insulin; Metoprol | 1983 |
Adrenergic blockade alters glucose kinetics during exercise in insulin-dependent diabetics.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; I | 1984 |
Non-insulin-treated ICA positive and negative diabetics are equally insulin resistant.
Topics: Adult; Antibodies; Autoantibodies; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 1983 |
Beta-adrenergic blockade is more effective in suppressing adrenaline-induced glucose production in Type 1 (insulin-dependent) diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucose; Humans; I | 1984 |
Epinephrine-induced hypoaminoacidemia in normal and diabetic human subjects: effect of beta blockade.
Topics: Adult; Amino Acids; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; | 1980 |
The squatting test. A useful tool to assess both parasympathetic and sympathetic involvement of the cardiovascular autonomic neuropathy in diabetes.
Topics: Adult; Age Factors; Aged; Atropine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic N | 1994 |
Stimulation of adipose tissue lipolysis following insulin-induced hypoglycaemia: evidence of increased beta-adrenoceptor-mediated lipolytic response in IDDM.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Analysis of Varian | 1996 |
Fatal asymptomatic hypoglycemia in an elderly insulin-dependent diabetic patient taking an oral beta-blocking medication.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Diabetes Mellitus, Type 1; Diabetic Angiopathies | 1998 |
Glucoregulation during and after intense exercise: effects of beta-adrenergic blockade in subjects with type 1 diabetes mellitus.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrin | 1999 |
Restoration of cardiac transient outward potassium current by norepinephrine in diabetic rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Nervous System Disease | 2000 |
Preclinical abnormality of cardiac function in juvenile-onset type diabetics: the effects of autonomic nervous blocking and dynamic exercise on cardiac function.
Topics: Adolescent; Adult; Atropine; Autonomic Nervous System; Diabetes Mellitus, Type 1; Echocardiography; | 1978 |
Studies on the mechanism of epinephrine-induced hyperglycemia in man. Evidence for participation of pancreatic glucagon secretion.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Synergism; Epinephrine; Fatty Acids, Nonesteri | 1976 |
Effect of adrenergic blockade on glucagon and growth hormone secretion in normal and diabetic children.
Topics: Adolescent; Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Horm | 1975 |
Glucose turnover in type I diabetic subjects during exercise. Effect of selective and nonselective beta-blockade and insulin withdrawal.
Topics: Adult; Atenolol; Betaxolol; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Glucose; Glycated He | 1992 |
Higher glycemic thresholds for symptoms during beta-adrenergic blockade in IDDM.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glucose Clam | 1991 |
Validation and evaluation of test for sympathetic cholinergic function in diabetes mellitus.
Topics: Adult; Age Factors; Aged; Atropine; Autonomic Nervous System; Diabetes Mellitus; Diabetes Mellitus, | 1991 |
Glucagon, catecholamine and pancreatic polypeptide secretion in type I diabetic recipients of pancreas allografts.
Topics: Arginine; Catecholamines; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Humans; Hypog | 1990 |
The effect of antihypertensive treatment on kidney function in insulin-dependent (type I) diabetics with renal failure.
Topics: Acute Kidney Injury; Antihypertensive Agents; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1; | 1990 |
[Diabetic cardiac dysautonomia. Clinical and pharmacologic evaluation].
Topics: Adolescent; Adult; Atropine; Autonomic Nervous System Diseases; Blood Pressure; Child; Diabetes Mell | 1989 |
Opposite effects of insulin and catecholamines on LDL-receptor activity in human mononuclear leukocytes.
Topics: Catecholamines; Diabetes Mellitus, Type 1; Epinephrine; Humans; In Vitro Techniques; Insulin; Isopro | 1988 |
Pathogenesis of the dawn phenomenon in patients with insulin-dependent diabetes mellitus. Accelerated glucose production and impaired glucose utilization due to nocturnal surges in growth hormone secretion.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hype | 1985 |
Mrs. McGiver's collapse--unmasking the true cause.
Topics: Aged; Diabetes Mellitus, Type 1; Female; Humans; Hypertension; Hypoglycemia; Propranolol; Syncope | 1989 |
Lack of beta-adrenergic role for catecholamines in the development of hyperglycemia and ketonaemia following acute insulin withdrawal in type I diabetic patients.
Topics: Adult; Catecholamines; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Glucagon; | 1985 |
Adrenergic modulation of potassium metabolism during exercise in normal and diabetic humans.
Topics: Adult; Bicarbonates; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Insulin; Kine | 1987 |
Hypoglycaemia precipitated by propranolol.
Topics: Adult; Aged; Diabetes Mellitus, Type 1; Female; Gastrectomy; Humans; Hypoglycemia; Insulin; Male; Pr | 1966 |
Growth hormoe and diabetic angiopathy.
Topics: Adolescent; Blood Glucose; Capillary Permeability; Child; Diabetes Mellitus; Diabetes Mellitus, Type | 1973 |
Glucagon mediation of growth hormone secretion in juvenile diabetes mellitus.
Topics: Adolescent; Blood Glucose; Body Weight; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Growth H | 1974 |