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propranolol and Depressive Disorder

propranolol has been researched along with Depressive Disorder in 49 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Research Excerpts

ExcerptRelevanceReference
"Assessment of an elderly depressed patient with an imipramine-induced tremor led to the conclusions that imipramine tremor (1) can be severe and incapacitating, (2) is most pronounced early in the treatment, (3) does not seem to be dose-related, and (4) is readily reversible with a beta-adrenergic blocking agent."7.66Imipramine-induced tremor: effects of a beta-adrenergic blocking agent. ( Greden, JF; Kronfol, Z; Zis, AP, 1983)
" Among the more important recent discoveries are the efficacy of the tricyclic antidepressants for panic disorder and agoraphobia with panic attacks; the use of the monoamine oxidase inhibitors for the above disorders and for atypical depression and hysteroid dysphoria; the use of propranolol for anxiety disorders and for uncontrollable violent outbursts; the antianxiety and antipanic effects of clonidine; and the usefulness of lithium in treating schizophrenia and schizoaffective disorder and for emotionally unstable character disorders."4.76Newer uses for older psychotropic medications. ( Liebowitz, MR, 1982)
"Propranolol was found to cause depression as a side effect with a statistically greater frequency than the control medications used in these trials."3.76Propranolol and depression: evidence from the antihypertensive trials. ( Patten, SB, 1990)
"We studied the occurrence of depression in new users of propranolol (n = 704), other beta-blockers (n = 587), angiotensin-converting enzyme inhibitors (n = 976), calcium channel blockers (n = 742), and diuretics (n = 773) in the Harvard Community Health Plan population."3.69The incidence of depression in new users of beta-blockers and selected antihypertensives. ( Bauer, M; Cho, P; Gerstman, BB; Jolson, HM; Livingston, JM; Platt, R, 1996)
"Assessment of an elderly depressed patient with an imipramine-induced tremor led to the conclusions that imipramine tremor (1) can be severe and incapacitating, (2) is most pronounced early in the treatment, (3) does not seem to be dose-related, and (4) is readily reversible with a beta-adrenergic blocking agent."3.66Imipramine-induced tremor: effects of a beta-adrenergic blocking agent. ( Greden, JF; Kronfol, Z; Zis, AP, 1983)
"A patient developed severe anxiety, moodswing, depression, and thinking disorder 24 hours after abruptly stopping oxazepam, of which he had taken 30 mg 3 times a day for two months, for anxiety and panic attacks."3.66Abstinence syndrome from therapeutic doses of oxazepam. ( Kulik, AV; Wilbur, R, 1983)
"As a result, SSRIinduced akathisia is very frequently under-recognized."1.40A case of akathisia induced by escitalopram: case report & review of literature. ( Basu, B; De, S; Dutta, N; Gangopadhyay, T; Mandal, B; Mondal, S, 2014)
"All three patients developed severe akathisia during retreatment with fluoxetine and stated that the development of the akathisia made them feel suicidal and that it had precipitated their prior suicide attempts."1.28Reexposure to fluoxetine after serious suicide attempts by three patients: the role of akathisia. ( Locke, CA; Rothschild, AJ, 1991)
" Although there was no correlation between propranolol dosage and depressive symptoms for the population as a whole, among patients with a negative history there was a highly significant positive correlation between propranolol dosage and depression scores."1.27Depressive symptoms in propranolol users. ( Friedman, MJ; Griffin, SJ, 1986)
"Patient compliance can be improved by reducing the complexity of drug dosage and by better labeling, packaging and informational exchange."1.26Once-a-day drug regimen for psychiatric patients. ( Hasan, MK; Mooney, RP, 1981)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199031 (63.27)18.7374
1990's11 (22.45)18.2507
2000's3 (6.12)29.6817
2010's3 (6.12)24.3611
2020's1 (2.04)2.80

Authors

AuthorsStudies
Sharma, VD1
Gupta, HV1
Espay, AJ1
Basu, B1
Gangopadhyay, T1
Dutta, N1
Mandal, B1
De, S1
Mondal, S1
Hymel, KA1
Eans, SO1
L Sitchenko, K1
Gomes, SM1
Lukowsky, AL1
Medina, JM1
Sypek, EI1
Carey, AN1
McLaughlin, JP1
Xiong, GL1
Gagliardi, JP1
Jiang, W1
Kirichenko, AA1
Ebzeeva, EIu1
Steffensmeier, JJ1
Ernst, ME1
Kelly, M1
Hartz, AJ1
Hasan, MK1
Mooney, RP1
Liebowitz, MR1
Johnson, JM1
Borsini, F1
Nowakowska, E1
Samanin, R1
Zohar, J1
Bannet, J1
Drummer, D1
Fisch, R1
Epstein, RP1
Belmaker, RH1
Gualtieri, CT1
Golden, RN1
Fahs, JJ1
Stoudemire, A1
Brown, JT1
Harris, RT1
Blessing-Feussner, C1
Roberts, JH1
Nichols, JC1
Houpt, JL1
Neppe, VM1
Oppenheim, G1
Husum, B1
Vester-Andersen, T1
Buchmann, G1
Bolwig, TG1
Tollefson, G1
Lesar, T1
Decina, P1
Malitz, S1
Sackeim, HA1
Holzer, J1
Yudofsky, S1
Nemeroff, CB1
Evans, DL1
Kronfol, Z1
Greden, JF1
Zis, AP1
Wilbur, R1
Kulik, AV1
Petrie, WM1
Maffucci, RJ1
Woosley, RL1
McNeil, GN1
Shaw, PK1
Dock, DS1
Kalayam, B1
Shamoian, CA1
Pariser, SF1
Reynolds, JC1
Falko, JM1
Jones, BA1
Mencer, DL1
Zavodnick, S1
Adler, LA2
Angrist, BM1
Gillette, DW1
Tannery, LP1
Gerstman, BB1
Jolson, HM1
Bauer, M1
Cho, P1
Livingston, JM1
Platt, R1
Eberstein, S1
Angrist, B1
Nurnberger, JI1
Adkins, S1
Lahiri, DK1
Mayeda, A1
Hu, K1
Lewy, A1
Miller, A1
Bowman, ES1
Miller, MJ1
Rau, L1
Smiley, C1
Davis-Singh, D1
Khaspekova, NB1
Loseva, MM1
Kuterman, EM1
Rothschild, AJ1
Locke, CA1
Fleischhacker, WW1
Callaway, E1
Halliday, R1
Perez-Stable, EJ1
Coates, TJ1
Hauck, WW1
Patten, SB1
Corwin, J1
Peselow, E1
Feenan, K1
Rotrosen, J1
Fieve, R1
Tang, SW1
Remington, G1
Persad, E1
Rosenblat, R1
Patterson, JF1
Noyes, R1
Breier, A1
Charney, DS1
Heninger, GR1
Butt, MM1
Silverstone, T1
Manchanda, R1
Bartels, D1
Glasser, M1
Wang, A1
Swanson, P1
Ginsberg, HN1
Griffin, SJ1
Friedman, MJ1
Jouvent, R1
Baruch, P1
Simon, P1
Pollack, MH1
Rosenbaum, JF1
Cassem, NH1

Reviews

8 reviews available for propranolol and Depressive Disorder

ArticleYear
Do randomized controlled trials always trump case reports? A second look at propranolol and depression.
    Pharmacotherapy, 2006, Volume: 26, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Depressive Disorder; Female; Humans; Male; Middle Aged; Proprano

2006
Newer uses for older psychotropic medications.
    Hospital & community psychiatry, 1982, Volume: 33, Issue:4

    Topics: Adrenergic beta-Antagonists; Agoraphobia; Anxiety Disorders; Bipolar Disorder; Clonidine; Depressive

1982
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
    The Journal of nervous and mental disease, 1984, Volume: 172, Issue:3

    Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic;

1984
New developments in pediatric psychopharmacology.
    Journal of developmental and behavioral pediatrics : JDBP, 1983, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Aggression; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Autistic Disorder

1983
Propranolol and depression: evidence from the antihypertensive trials.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1990, Volume: 35, Issue:3

    Topics: Clinical Trials as Topic; Depressive Disorder; Humans; Hypertension; Meta-Analysis as Topic; Propran

1990
Beta-adrenergic blocking drugs in anxiety and stress.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Asthma; Benzodiazepine

1985
The diagnostic validity of anxiety disorders and their relationship to depressive illness.
    The American journal of psychiatry, 1985, Volume: 142, Issue:7

    Topics: Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; Caffeine; Clonidine;

1985
Mood and food. A psychopharmacological enquiry.
    Annals of the New York Academy of Sciences, 1987, Volume: 499

    Topics: Depressive Disorder; Dextroamphetamine; Emotions; Food; Humans; Hunger; Moxisylyte; Propranolol; Rec

1987

Trials

9 trials available for propranolol and Depressive Disorder

ArticleYear
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
    The Journal of nervous and mental disease, 1984, Volume: 172, Issue:3

    Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic;

1984
New developments in pediatric psychopharmacology.
    Journal of developmental and behavioral pediatrics : JDBP, 1983, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Aggression; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Autistic Disorder

1983
Propranolol and depression: a reevaluation based on a pilot clinical trial.
    Psychiatric medicine, 1984, Volume: 2, Issue:2

    Topics: Aged; Benzothiadiazines; Clinical Trials as Topic; Depressive Disorder; Diuretics; Female; Humans; M

1984
[Evaluation of the effectiveness of drug therapy of autonomic paroxysms in relation to the variability of cardiac rhythm].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1991, Volume: 91, Issue:5

    Topics: Adult; Anxiety Disorders; Autonomic Nervous System Diseases; Depressive Disorder; Diazepam; Heart Ra

1991
Propranolol and depression: evidence from the antihypertensive trials.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1990, Volume: 35, Issue:3

    Topics: Clinical Trials as Topic; Depressive Disorder; Humans; Hypertension; Meta-Analysis as Topic; Propran

1990
Disorders of decision in affective disease: an effect of beta-adrenergic dysfunction?
    Biological psychiatry, 1990, Apr-15, Volume: 27, Issue:8

    Topics: Arousal; Attention; Bipolar Disorder; Brain; Clinical Trials as Topic; Decision Making; Depressive D

1990
Coadministration of a beta-adrenergic antagonist and a tricyclic antidepressant: a pilot study.
    Psychiatry research, 1990, Volume: 33, Issue:2

    Topics: Depressive Disorder; Desipramine; Drug Therapy, Combination; Humans; Pilot Projects; Propranolol; Ps

1990
Beta-adrenergic blocking drugs in anxiety and stress.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Asthma; Benzodiazepine

1985
Dextro-propranolol and depressive symptoms in a schizophrenic population.
    Progress in neuro-psychopharmacology & biological psychiatry, 1987, Volume: 11, Issue:5

    Topics: Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Humans; Propranolol; Psychiatric

1987

Other Studies

36 other studies available for propranolol and Depressive Disorder

ArticleYear
Copulatory Dyskinesia: Pathognomonic Manifestation of Tardive Dyskinesia.
    Tremor and other hyperkinetic movements (New York, N.Y.), 2020, 12-16, Volume: 10

    Topics: Adrenergic beta-Antagonists; Aged; Aripiprazole; Clonazepam; Deprescriptions; Depressive Disorder; D

2020
A case of akathisia induced by escitalopram: case report & review of literature.
    Current drug safety, 2014, Volume: 9, Issue:1

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Second-Generation; Breast Neoplasms; Citalopram;

2014
Stress-induced increases in depression-like and cocaine place-conditioned behaviors are reversed by disruption of memories during reconsolidation.
    Behavioural pharmacology, 2014, Volume: 25, Issue:5-6

    Topics: Adrenergic beta-Antagonists; Animals; Cocaine; Conditioning, Psychological; Cycloheximide; Depressiv

2014
Beta-blockers and depression.
    The American journal of psychiatry, 2010, Volume: 167, Issue:2

    Topics: Adrenergic beta-Antagonists; Depressive Disorder; Electroconvulsive Therapy; Humans; Propranolol; Ta

2010
[The role of depressive disorders in hypertensive disease and possibilities of their correction: assessment of the effect of tianeptine].
    Kardiologiia, 2002, Volume: 42, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antidepressive A

2002
Once-a-day drug regimen for psychiatric patients.
    American family physician, 1981, Volume: 24, Issue:4

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Anxiety; Depressive Disorder; Drug Administratio

1981
Effect of repeated treatment with desipramine in the behavioral "despair" test in rats: antagonism by "atypical" but not "classical" neuroleptics or antiadrenergic drugs.
    Life sciences, 1984, Mar-19, Volume: 34, Issue:12

    Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Clonidi

1984
The response of lymphocyte beta-adrenergic receptors to chronic propranolol treatment in depressed patients, schizophrenic patients, and normal controls.
    Biological psychiatry, 1983, Volume: 18, Issue:5

    Topics: Adult; Chronic Disease; Depressive Disorder; Dihydroalprenolol; Double-Blind Method; Female; Humans;

1983
Propranolol, depression, and nortriptyline interaction.
    The American journal of psychiatry, 1984, Volume: 141, Issue:8

    Topics: Depressive Disorder; Drug Interactions; Humans; Nortriptyline; Propranolol

1984
Propranolol-induced depression: mechanism and management.
    The Australian and New Zealand journal of psychiatry, 1983, Volume: 17, Issue:4

    Topics: Adult; Angina Pectoris; Atenolol; Depressive Disorder; Female; Humans; Hypertension; Male; Middle Ag

1983
Electroconvulsive therapy and intracranial aneurysm. Prevention of blood pressure elevation in a normotensive patient by hydralazine and propranolol.
    Anaesthesia, 1983, Volume: 38, Issue:12

    Topics: Adult; Anesthesia, Intravenous; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Hydr

1983
Effect of propranolol on maprotiline clearance.
    The American journal of psychiatry, 1984, Volume: 141, Issue:1

    Topics: Adult; Anthracenes; Depressive Disorder; Drug Interactions; Humans; Hydroxylation; Liver Circulation

1984
Cardiac arrest during ECT modified by beta-adrenergic blockade.
    The American journal of psychiatry, 1984, Volume: 141, Issue:2

    Topics: Aged; Coronary Disease; Depressive Disorder; Diabetes Complications; Electroconvulsive Therapy; Fema

1984
Concurrent use of antidepressants and propranolol: case report and theoretical considerations.
    Biological psychiatry, 1983, Volume: 18, Issue:2

    Topics: Anthracenes; Depressive Disorder; Drug Therapy, Combination; Humans; Male; Maprotiline; Middle Aged;

1983
Imipramine-induced tremor: effects of a beta-adrenergic blocking agent.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:6

    Topics: Depressive Disorder; Humans; Imipramine; Male; Middle Aged; Propranolol; Tremor

1983
Abstinence syndrome from therapeutic doses of oxazepam.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1983, Volume: 28, Issue:4

    Topics: Adult; Anxiety; Depression; Depressive Disorder; Diazepam; Fasciculation; Fear; Humans; Male; Oxazep

1983
Propranolol and depression.
    The American journal of psychiatry, 1982, Volume: 139, Issue:1

    Topics: Adult; Arrhythmias, Cardiac; Depressive Disorder; Dose-Response Relationship, Drug; Female; Humans;

1982
Substitution of atenolol for propranolol in a case of propranolol-related depression.
    The American journal of psychiatry, 1982, Volume: 139, Issue:9

    Topics: Angina Pectoris; Atenolol; Depressive Disorder; Female; Humans; Hypertension; Imipramine; Middle Age

1982
Propranolol, psychoneuroendocrine changes, and depression.
    The American journal of psychiatry, 1982, Volume: 139, Issue:10

    Topics: Aged; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Lithium; Propranolol; Trem

1982
Arrhythmia induced by a tricyclic antidepressant in a patient with undiagnosed mitral valve prolapse.
    The American journal of psychiatry, 1981, Volume: 138, Issue:4

    Topics: Adult; Arrhythmias, Cardiac; Depressive Disorder; Desipramine; Female; Humans; Mitral Valve Prolapse

1981
Atrial flutter with amoxapine: a case report.
    The American journal of psychiatry, 1981, Volume: 138, Issue:11

    Topics: Aged; Amoxapine; Atrial Flutter; Depressive Disorder; Dibenzoxazepines; Electrocardiography; Humans;

1981
Paroxetine and akathisia.
    Biological psychiatry, 1995, Mar-01, Volume: 37, Issue:5

    Topics: Akathisia, Drug-Induced; Clonazepam; Depressive Disorder; Dose-Response Relationship, Drug; Drug Adm

1995
Beta blocker inhibits tricyclic metabolism.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1994, Volume: 33, Issue:2

    Topics: Adrenergic beta-Antagonists; Aggression; Anger; Antidepressive Agents, Tricyclic; Child; Depressive

1994
The incidence of depression in new users of beta-blockers and selected antihypertensives.
    Journal of clinical epidemiology, 1996, Volume: 49, Issue:7

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calc

1996
Nefazodone and akathisia.
    Biological psychiatry, 1996, Oct-15, Volume: 40, Issue:8

    Topics: Akathisia, Drug-Induced; Antidepressive Agents, Second-Generation; Clonazepam; Depressive Disorder;

1996
Melatonin suppression by light in euthymic bipolar and unipolar patients.
    Archives of general psychiatry, 2000, Volume: 57, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Female;

2000
Reexposure to fluoxetine after serious suicide attempts by three patients: the role of akathisia.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:12

    Topics: Adult; Akathisia, Drug-Induced; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxetine;

1991
Propanolol for fluoxetine-induced akathisia.
    Biological psychiatry, 1991, Sep-01, Volume: 30, Issue:5

    Topics: Akathisia, Drug-Induced; Depressive Disorder; Female; Fluoxetine; Humans; Middle Aged; Neurologic Ex

1991
Propranolol and response bias: an extension of findings reported by Corwin et al.
    Biological psychiatry, 1991, Oct-01, Volume: 30, Issue:7

    Topics: Adolescent; Adult; Arousal; Bias; Depressive Disorder; Dose-Response Relationship, Drug; Female; Hum

1991
Depression associated with enalapril.
    Southern medical journal, 1989, Volume: 82, Issue:3

    Topics: Atenolol; Depressive Disorder; Enalapril; Female; Humans; Middle Aged; Propranolol

1989
Managing antidepressant-induced sweating.
    The Journal of clinical psychiatry, 1989, Volume: 50, Issue:4

    Topics: Depressive Disorder; Female; Humans; Imipramine; Propranolol; Sweating

1989
Association between depression and propranolol use in ambulatory patients.
    Clinical pharmacy, 1988, Volume: 7, Issue:2

    Topics: Depressive Disorder; Dexamethasone; Female; Humans; Male; Propranolol

1988
Propranolol in the treatment of restless legs syndrome induced by imipramine withdrawal.
    The American journal of psychiatry, 1986, Volume: 143, Issue:7

    Topics: Depressive Disorder; Female; Humans; Imipramine; Middle Aged; Propranolol; Restless Legs Syndrome; S

1986
Depressive symptoms in propranolol users.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:9

    Topics: Administration, Oral; Age Factors; Aged; Cardiovascular Diseases; Depression; Depressive Disorder; H

1986
Manic episode after propranolol withdrawal.
    The American journal of psychiatry, 1986, Volume: 143, Issue:12

    Topics: Bipolar Disorder; Clomipramine; Depressive Disorder; Female; Humans; Middle Aged; Propranolol; Subst

1986
Propranolol and depression revisited: three cases and a review.
    The Journal of nervous and mental disease, 1985, Volume: 173, Issue:2

    Topics: Aged; Arrhythmias, Cardiac; Depressive Disorder; Dose-Response Relationship, Drug; Female; Humans; H

1985