Page last updated: 2024-11-03

propranolol and Depression, Involutional

propranolol has been researched along with Depression, Involutional in 6 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.

Research Excerpts

ExcerptRelevanceReference
"Propranolol or a placebo was administered 90 min before a brief memory reactivation session, once a week for 6 consecutive weeks."3.01Traumatic memory reactivation with or without propranolol for PTSD and comorbid MD symptoms: a randomised clinical trial. ( Birmes, P; Bourcier, A; Dupuch, L; El Hage, W; Jasse, L; Lamy, P; Roullet, P; Thalamas, C; Vaiva, G; Véry, E; Yrondi, A, 2021)
" Here, we investigated the roles of Cyp1a2 and Cyp2d on DLX pharmacokinetic profile and tissue distribution using a Cyp1a2 knockout (Cyp1a2-KO) mouse model together with a Cyp2d inhibitor (propranolol)."1.91The roles of Cyp1a2 and Cyp2d in pharmacokinetic profiles of serotonin and norepinephrine reuptake inhibitor duloxetine and its metabolites in mice. ( Barzi, M; Bissig, KD; Boyd, SR; Hakenjos, JM; Li, F; MacKenzie, KR; Qin, X; Xie, C; Young, DW, 2023)
"A 31-year-old man with major depressive disorder was found dead in his dormitory room."1.46Fatal Self-Poisoning With Massive Propranolol Ingestion in a Young Male Physician. ( Srettabunjong, S, 2017)
"Propranolol was effective in treating acute pathological panic, but modest doses of the drug administered for brief periods of time did not alleviate chronic panic attacks associated with agoraphobia."1.26The treatment of pathological panic states with propranolol. ( Defrancisco, D; Heiser, JF, 1976)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Qin, X2
Xie, C2
Hakenjos, JM2
MacKenzie, KR2
Boyd, SR2
Barzi, M2
Bissig, KD2
Young, DW2
Li, F2
Fujita, S1
Yoshida, S1
Matsuki, T1
Jaiswal, MK1
Seki, K1
Roullet, P1
Vaiva, G1
Véry, E1
Bourcier, A1
Yrondi, A1
Dupuch, L1
Lamy, P1
Thalamas, C1
Jasse, L1
El Hage, W1
Birmes, P1
Srettabunjong, S1
Räsänen, P1
Hakko, H1
Tiihonen, J1
Heiser, JF1
Defrancisco, D1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Pediatric Post-traumatic Stress Disorder With Memory Reactivation Under the Influence of Propranolol: A Randomized Placebo-controlled Trial. PPP[NCT04985344]Phase 392 participants (Anticipated)Interventional2023-02-01Recruiting
Treatment of PTSD by Reduction of Traumatic Memory Reconsolidation by Propranolol : a Multisite Trial[NCT01713556]Phase 287 participants (Actual)Interventional2012-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for propranolol and Depression, Involutional

ArticleYear
Traumatic memory reactivation with or without propranolol for PTSD and comorbid MD symptoms: a randomised clinical trial.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2021, Volume: 46, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Depressive Disorder, Major; Humans; Propranolol; Stress Disorder

2021
Traumatic memory reactivation with or without propranolol for PTSD and comorbid MD symptoms: a randomised clinical trial.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2021, Volume: 46, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Depressive Disorder, Major; Humans; Propranolol; Stress Disorder

2021
Traumatic memory reactivation with or without propranolol for PTSD and comorbid MD symptoms: a randomised clinical trial.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2021, Volume: 46, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Depressive Disorder, Major; Humans; Propranolol; Stress Disorder

2021
Traumatic memory reactivation with or without propranolol for PTSD and comorbid MD symptoms: a randomised clinical trial.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2021, Volume: 46, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Depressive Disorder, Major; Humans; Propranolol; Stress Disorder

2021

Other Studies

5 other studies available for propranolol and Depression, Involutional

ArticleYear
The roles of Cyp1a2 and Cyp2d in pharmacokinetic profiles of serotonin and norepinephrine reuptake inhibitor duloxetine and its metabolites in mice.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2023, Feb-01, Volume: 181

    Topics: Animals; Central Nervous System Agents; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Depressive

2023
The roles of Cyp1a2 and Cyp2d in pharmacokinetic profiles of serotonin and norepinephrine reuptake inhibitor duloxetine and its metabolites in mice.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2023, Feb-01, Volume: 181

    Topics: Animals; Central Nervous System Agents; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Depressive

2023
The roles of Cyp1a2 and Cyp2d in pharmacokinetic profiles of serotonin and norepinephrine reuptake inhibitor duloxetine and its metabolites in mice.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2023, Feb-01, Volume: 181

    Topics: Animals; Central Nervous System Agents; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Depressive

2023
The roles of Cyp1a2 and Cyp2d in pharmacokinetic profiles of serotonin and norepinephrine reuptake inhibitor duloxetine and its metabolites in mice.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2023, Feb-01, Volume: 181

    Topics: Animals; Central Nervous System Agents; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Depressive

2023
The α1-adrenergic receptors in the amygdala regulate the induction of learned despair through protein kinase C-beta signaling.
    Behavioural pharmacology, 2021, 02-01, Volume: 32, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Amygdala; Animals; Depressive

2021
Fatal Self-Poisoning With Massive Propranolol Ingestion in a Young Male Physician.
    The American journal of forensic medicine and pathology, 2017, Volume: 38, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Depressive Disorder, Major; Gastrointestinal Contents; Humans; M

2017
Mitchell B. Balter Award--1998. Pindolol and major affective disorders: a three-year follow-up study of 30,485 patients.
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:4

    Topics: Adrenergic beta-Antagonists; Atenolol; Depressive Disorder, Major; Disability Evaluation; Drug Thera

1999
The treatment of pathological panic states with propranolol.
    The American journal of psychiatry, 1976, Volume: 133, Issue:12

    Topics: Acute Disease; Adult; Agoraphobia; Anxiety Disorders; Chronic Disease; Depression; Depressive Disord

1976