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propranolol and Dementia

propranolol has been researched along with Dementia in 13 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
"Although several reports suggest that intermediate to high doses of propranolol (80-160 and 200-600 mg/day) can effectively treat aggressive behavior in dementia, significant side effects can occur at these doses."7.69Low-dose propranolol reduces aggression and agitation resembling that associated with orbitofrontal dysfunction in elderly demented patients. ( Cotman, CW; Nielson, KA; Shankle, WR, 1995)
"Although several reports suggest that intermediate to high doses of propranolol (80-160 and 200-600 mg/day) can effectively treat aggressive behavior in dementia, significant side effects can occur at these doses."3.69Low-dose propranolol reduces aggression and agitation resembling that associated with orbitofrontal dysfunction in elderly demented patients. ( Cotman, CW; Nielson, KA; Shankle, WR, 1995)
" In the antipsychotic classification, special attention is given to side effects (extrapyramidal motor signs, tardive dyskinesias, akathisis) and to dosage for the elderly."1.25Observations on the psychopharmacology of the aged. ( Eisdorfer, C, 1975)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's3 (23.08)18.2507
2000's3 (23.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Peters, R1
Beckett, N1
Hirai, S1
Summers, WK1
Petrie, WM1
Ban, TA1
Jenike, MA1
Sulkowski, A1
Shankle, WR1
Nielson, KA1
Cotman, CW1
Tariot, PN1
Eisdorfer, C1
Pauszek, ME1
Eimer, M1
Risse, SC1
Barnes, R1
Judge, TG1

Reviews

6 reviews available for propranolol and Dementia

ArticleYear
Hypertension, dementia, and antihypertensive treatment: implications for the very elderly.
    Current hypertension reports, 2009, Volume: 11, Issue:4

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inh

2009
[Dementia induced by cardiokinetic and anti-hypertensive drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl

    Topics: Antihypertensive Agents; Cardiotonic Agents; Clonidine; Dementia; Digitoxin; Digoxin; Half-Life; Hum

2004
Treatment of agitation in dementia.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 8

    Topics: Caregivers; Confusion; Decision Trees; Dementia; Electroconvulsive Therapy; Estrogens; Humans; Lithi

1999
Management of the behavioral symptoms associated with dementia.
    Primary care, 1989, Volume: 16, Issue:2

    Topics: Aged; Aggression; Antipsychotic Agents; Dementia; Humans; Pindolol; Propranolol; Psychomotor Agitati

1989
Pharmacologic treatment of agitation associated with dementia.
    Journal of the American Geriatrics Society, 1986, Volume: 34, Issue:5

    Topics: Affective Symptoms; Aged; Aggression; Alzheimer Disease; Anti-Anxiety Agents; Antipsychotic Agents;

1986
Vasodilators..
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenergic alpha-Antagonists; Aminophylline; Angina Pectoris; Bradycardia; Bronchial Diseases; Cereb

1974

Other Studies

7 other studies available for propranolol and Dementia

ArticleYear
The management of agitation in demented patients with propranolol.
    Journal of Alzheimer's disease : JAD, 2006, Volume: 9, Issue:1

    Topics: Aged; Antipsychotic Agents; Bronchial Spasm; Dementia; Disease Management; Humans; Male; Propranolol

2006
Propranolol in organic agitation.
    Lancet (London, England), 1981, Feb-07, Volume: 1, Issue:8215

    Topics: Aged; Dementia; Female; Humans; Male; Middle Aged; Propranolol; Psychomotor Agitation

1981
Treating the violent elderly patient with propranolol.
    Geriatrics, 1983, Volume: 38, Issue:3

    Topics: Aged; Dementia; Female; Humans; Male; Middle Aged; Propranolol; Violence

1983
Marihuana "high":a model of senile dementia?
    Perspectives in biology and medicine, 1980,Winter, Volume: 23, Issue:2 PT1

    Topics: Aged; Alzheimer Disease; Brain; Cannabis; Cognition; Dementia; Humans; Models, Biological; Propranol

1980
Low-dose propranolol reduces aggression and agitation resembling that associated with orbitofrontal dysfunction in elderly demented patients.
    Alzheimer disease and associated disorders, 1995,Winter, Volume: 9, Issue:4

    Topics: Aged; Aggression; Alzheimer Disease; Dementia; Female; Humans; Male; Middle Aged; Propranolol; Psych

1995
Observations on the psychopharmacology of the aged.
    Journal of the American Geriatrics Society, 1975, Volume: 23, Issue:2

    Topics: Aged; Amantadine; Antidepressive Agents; Antipsychotic Agents; Basal Ganglia Diseases; Butyrophenone

1975
Propranolol for treatment of agitation in senile dementia.
    Indiana medicine : the journal of the Indiana State Medical Association, 1991, Volume: 84, Issue:1

    Topics: Aged; Dementia; Humans; Male; Propranolol; Psychomotor Agitation

1991