Page last updated: 2024-11-03

propranolol and Cushing Syndrome

propranolol has been researched along with Cushing Syndrome in 13 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.

Research Excerpts

ExcerptRelevanceReference
"Four children with haemangiomas of the head and neck were treated with propranolol at a tertiary referral centre."7.77Failure of propranolol in the treatment of childhood haemangiomas of the head and neck. ( Bruce, IA; Goswamy, J; Rothera, MP, 2011)
"Four children with haemangiomas of the head and neck were treated with propranolol at a tertiary referral centre."3.77Failure of propranolol in the treatment of childhood haemangiomas of the head and neck. ( Bruce, IA; Goswamy, J; Rothera, MP, 2011)
"A direct binding study of radioligand [3H]dihydroalprenolol (DHA), a potent beta-adrenergic antagonist, was performed on the particulate fractions of four adrenocortical adenomas (three cortisol-producing adenomas and one aldosterone-producing adenoma) and normal adrenal tissues."3.66Presence of ectopic beta-adrenergic receptors on human adrenocortical cortisol-producing adenomas. ( Fujita, T; Hirata, Y; Matsukura, S; Sueoka, S; Uchihashi, M, 1981)
" Lowering propranolol dosage or switching to atenolol was less efficient to reduce cortisol levels."1.35Adrenal Cushing's syndrome due to bilateral macronodular adrenal hyperplasia: prediction of the efficacy of beta-blockade therapy and interest of unilateral adrenalectomy. ( Chabre, O; Chaffanjon, P; Martinie, M; Mazzuco, TL; Sturm, N, 2009)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's2 (15.38)18.2507
2000's2 (15.38)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bourdeau, I1
Oble, S1
Magne, F1
Lévesque, I1
Cáceres-Gorriti, KY1
Nolet, S1
Awadalla, P1
Tremblay, J2
Hamet, P2
Fragoso, MC1
Lacroix, A2
Mazzuco, TL1
Chaffanjon, P1
Martinie, M1
Sturm, N1
Chabre, O1
Oki, K1
Yamane, K1
Nakanishi, S1
Nakashima, R1
Jitsuiki, K1
Kohno, N1
Goswamy, J1
Rothera, MP1
Bruce, IA1
Pinto Valdivia, M1
Arnez, L1
Portela, M1
Biagetti, B1
Mesa, J1
Hirata, Y1
Uchihashi, M1
Sueoka, S1
Matsukura, S1
Fujita, T1
Hofmockel, G1
Heimbach, D1
Bussen, D1
Reincke, M1
Frohmüller, HG1
Rousseau, G1
Bouvier, M1
Cugini, P1
Lupi, A1
Manconi, R1
Bard, RH1
Ikeda, M1
Hattori, Y1
Tsunoda, Y1
Amaha, K1
Ikezono, E1

Other Studies

13 other studies available for propranolol and Cushing Syndrome

ArticleYear
ARMC5 mutations in a large French-Canadian family with cortisol-secreting β-adrenergic/vasopressin responsive bilateral macronodular adrenal hyperplasia.
    European journal of endocrinology, 2016, Volume: 174, Issue:1

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenergic beta-Agonists; Adrenergic

2016
Adrenal Cushing's syndrome due to bilateral macronodular adrenal hyperplasia: prediction of the efficacy of beta-blockade therapy and interest of unilateral adrenalectomy.
    Endocrine journal, 2009, Volume: 56, Issue:7

    Topics: Adrenal Glands; Adrenalectomy; Adrenergic beta-Antagonists; Atenolol; Cushing Syndrome; Female; Huma

2009
Improvement of hypercortisolism by β-blocker therapy in subclinical Cushing's syndrome associated with ACTH-independent macronodular adrenocortical hyperplasia.
    Endocrine, 2009, Volume: 36, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenergic beta-Antagonists; Adrenocorticotropic H

2009
Failure of propranolol in the treatment of childhood haemangiomas of the head and neck.
    The Journal of laryngology and otology, 2011, Volume: 125, Issue:11

    Topics: Adrenal Cortex Hormones; Airway Obstruction; Anti-Inflammatory Agents; Combined Modality Therapy; Co

2011
[Lupus, Graves' disease, and vasculitis: a case report].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:3

    Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Autoantibodies; Cushing Syndrome; Dipyro

2012
[Cushing syndrome with clinical response to beta-blockers].
    Medicina clinica, 2012, Oct-13, Volume: 139, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Cushing Syndrome; Female; Humans; Propranolol

2012
Presence of ectopic beta-adrenergic receptors on human adrenocortical cortisol-producing adenomas.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:5

    Topics: Adenoma; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Cell Membrane;

1981
[Surgical interventions of the adrenal gland. Diagnosis and results of treatment].
    Der Urologe. Ausg. A, 1994, Volume: 33, Issue:6

    Topics: Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma;

1994
Propranolol therapy for ectopic beta-adrenergic receptors in adrenal Cushing's syndrome.
    The New England journal of medicine, 1997, Nov-13, Volume: 337, Issue:20

    Topics: Adrenal Glands; Adrenergic beta-Antagonists; Catecholamines; Cushing Syndrome; Humans; Hydrocortison

1997
[Influence of propranolol on the response of blood cortisol to lysine-vasopressin and on the daily changes of blood cortisol in the diencephalo-hypophyscal Cushing's syndrome].
    Bollettino della Societa italiana di biologia sperimentale, 1975, Dec-15, Volume: 51, Issue:23

    Topics: Adolescent; Adult; Circadian Rhythm; Cushing Syndrome; Diencephalon; Female; Humans; Hydrocortisone;

1975
Operative and nonoperative hypertension. Recent advances in treatment.
    Urology, 1976, Volume: 7, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Cushing Syndrome; Diuretics; Humans; Hyperaldosteronism; Hyper

1976
[Plasma insulin levels in endocrine diseases. 3. Plasma insulin levels in patients with adrenal gland diseases and during steroid treatment].
    Nihon Naibunpi Gakkai zasshi, 1973, Volume: 49, Issue:10

    Topics: Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Blood Glucose; Child; Cushing Sy

1973
[Anesthetic experiences in adrenalectomy in patients with Cushing's syndrome].
    Masui. The Japanese journal of anesthesiology, 1968, Volume: 17, Issue:3

    Topics: Adolescent; Adrenalectomy; Adult; Anesthesia, Endotracheal; Cushing Syndrome; Female; Humans; Pituit

1968