propranolol has been researched along with Crohn Disease in 12 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the importance of disease-induced increases in plasma concentrations of alpha1 acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined binding of propranolol in plasma from 53 patients and 25 healthy volunteers." | 7.66 | Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein. ( Borgá, O; Johansson, C; Odar-Cederlöf, I; Piafsky, KM; Sjöqvist, F, 1978) |
| "To assess the importance of disease-induced increases in plasma concentrations of alpha1 acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined binding of propranolol in plasma from 53 patients and 25 healthy volunteers." | 3.66 | Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein. ( Borgá, O; Johansson, C; Odar-Cederlöf, I; Piafsky, KM; Sjöqvist, F, 1978) |
| " The plasma propranolol concentrations after a single oral dose of 40 mg were measured in 25 patients with rheumatoid arthritis and compared with those of 16 patients with Crohn's disease from a previous study." | 3.66 | Plasma propranolol concentrations and the erythrocyte sedimentation rate. ( Bishop, H; Hawkins, CF; Schneider, RE, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (91.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Waller, DG | 1 |
| Smith, CL | 1 |
| Renwick, AG | 1 |
| George, CF | 1 |
| Tenore, A | 1 |
| Berman, WF | 1 |
| Parks, JS | 1 |
| Bongiovanni, AM | 1 |
| Piafsky, KM | 1 |
| Borgá, O | 1 |
| Odar-Cederlöf, I | 1 |
| Johansson, C | 1 |
| Sjöqvist, F | 1 |
| Schneider, RE | 4 |
| Bishop, H | 4 |
| Hawkins, CF | 3 |
| Kitis, G | 1 |
| Parsons, RL | 1 |
| Trounce, JR | 1 |
| Kaye, CM | 1 |
| Babb, J | 2 |
| Mitchard, M | 1 |
| Hoare, AM | 2 |
| Cooper, BT | 1 |
| Cooke, WT | 1 |
| Lucas, ML | 1 |
| Blair, JA | 1 |
| Beckh, K | 1 |
| Sieg, I | 1 |
| Stellwaag, M | 1 |
| Blanke, H | 1 |
| Arnold, R | 1 |
| Doss, M | 1 |
| Rösch, J | 1 |
| Dotter, CT | 1 |
| Rose, RW | 1 |
12 other studies available for propranolol and Crohn Disease
| Article | Year |
|---|---|
Intravenous propranolol in patients with inflammation.
Topics: Adult; Aged; Arthritis, Rheumatoid; Crohn Disease; Humans; Inflammation; Injections, Intravenous; Ki | 1982 |
Basal and stimulated serum growth hormone concentrations in inflammatory bowel disease.
Topics: Adolescent; Animals; Body Height; Body Weight; Child; Colitis, Ulcerative; Crohn Disease; Female; Gl | 1977 |
Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein.
Topics: Adult; Aged; alpha-Macroglobulins; Arthritis; Chlorpromazine; Crohn Disease; Disease; Female; Humans | 1978 |
Drug binding to alpha 1-glycoprotein.
Topics: Arthritis, Rheumatoid; Biological Availability; Crohn Disease; Glycoproteins; Half-Life; Humans; Pro | 1979 |
Plasma propranolol concentrations and the erythrocyte sedimentation rate.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Crohn Disease; Female; Humans; Male; Middle | 1979 |
Propranolol absorption in Crohn's disease and coeliac disease.
Topics: Celiac Disease; Crohn Disease; Humans; Intestinal Absorption; Propranolol | 1977 |
Plasma propranolol levels in Crohn's disease and coeliac disease.
Topics: Adult; Celiac Disease; Crohn Disease; Humans; Propranolol; Time Factors | 1977 |
Plasma levels of propranolol in treated patients with coeliac disease and patients with Crohn's disease.
Topics: Adolescent; Adult; Aged; Celiac Disease; Crohn Disease; Female; Humans; Male; Middle Aged; Propranol | 1976 |
Propranolol absorption in Crohn's disease and coeliac disease.
Topics: Celiac Disease; Crohn Disease; Humans; Intestinal Absorption; Propranolol | 1976 |
Plasma propranolol levels in coeliac disease and Crohn's disease.
Topics: Celiac Disease; Crohn Disease; Humans; Propranolol | 1976 |
[The coincidence of acute intermittent porphyria and Crohn's disease].
Topics: Acute Disease; Adult; Arginine; Crohn Disease; Diagnosis, Differential; Drug Therapy, Combination; G | 1990 |
Selective arterial infusions of vasoconstrictors in acute gastrointestinal bleeding.
Topics: Acute Disease; Adolescent; Adult; Aged; Angiography; Arteriosclerosis; Celiac Artery; Crohn Disease; | 1971 |