propranolol has been researched along with Craniocerebral Trauma in 13 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Craniocerebral Trauma: Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared the central and renal haemodynamic effects of tertatolol, a new non-cardioselective beta-adrenergic blocking drug without partial agonist activity, with those of an equipotent dosage of propranolol in two groups of 10 patients each with acute cerebral injury who had developed systemic hypertension." | 9.06 | Acute central and renal haemodynamic responses to tertatolol and propranolol in patients with arterial hypertension following head injury. ( Brackman, F; Degaute, JP; Leeman, M; Naeije, R; Prost, JF, 1986) |
| " Its central and renal hemodynamic effects were compared to those of an equipotent dosage of propranolol in two groups of 10 patients each who developed arterial hypertension and a hyperdynamic circulatory state after head injury." | 7.67 | Tertatolol preserves renal perfusion in patients with arterial hypertension after head injury. ( Brackman, F; Degaute, JP; Leeman, M; Naeije, R; Prost, JF; Thomas, J, 1986) |
| "We compared the central and renal haemodynamic effects of tertatolol, a new non-cardioselective beta-adrenergic blocking drug without partial agonist activity, with those of an equipotent dosage of propranolol in two groups of 10 patients each with acute cerebral injury who had developed systemic hypertension." | 5.06 | Acute central and renal haemodynamic responses to tertatolol and propranolol in patients with arterial hypertension following head injury. ( Brackman, F; Degaute, JP; Leeman, M; Naeije, R; Prost, JF, 1986) |
| " Its central and renal hemodynamic effects were compared to those of an equipotent dosage of propranolol in two groups of 10 patients each who developed arterial hypertension and a hyperdynamic circulatory state after head injury." | 3.67 | Tertatolol preserves renal perfusion in patients with arterial hypertension after head injury. ( Brackman, F; Degaute, JP; Leeman, M; Naeije, R; Prost, JF; Thomas, J, 1986) |
| "The response to prophylactic anti-migraine medication (propranolol or amitriptyline used alone or in combination) was gratifying, with 21 of 30 adequately treated patients (70%) reporting dramatic reduction in the frequency and severity of their headaches." | 1.28 | Post-traumatic migraine: chronic migraine precipitated by minor head or neck trauma. ( Goldberg, J; Stern, BJ; Weiss, HD, 1991) |
| "The interval between head trauma to onset of symptoms was 1 to 4 weeks." | 1.28 | Post-traumatic tremor. ( Biary, N; Cleeves, L; Findley, L; Koller, W, 1989) |
| "Propranolol appears to be a useful antihypertensive drug in the hyperdynamic head-injured patient because it normalizes blood pressure and the underlying hemodynamic abnormalities both by its beta-adrenergic blocking action and by decreasing circulating levels of catecholamines." | 1.27 | Treatment of hypertension associated with head injury. ( Clifton, GL; Grossman, RG; Robertson, CS; Taylor, AA, 1983) |
| "The atropine test was found to be an efficient and simple diagnostic aid in cases of brain death." | 1.25 | Electrocardiographic findings in brain death; description and presumed mechanism. ( Drory, Y; Kellermann, JJ; Kosary, IZ; Ouaknine, G, 1975) |
| "Three of the 10 members had hemiplegic migraine attacks associated with minor head trauma." | 1.25 | Familial hemiplegic migraine. ( Glista, GG; Mellinger, JF; Rooke, ED, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Williamson, JE | 1 |
| Maddock, S | 1 |
| Castillo, V | 1 |
| Carbajal, R | 1 |
| Robertson, CS | 1 |
| Clifton, GL | 1 |
| Taylor, AA | 1 |
| Grossman, RG | 1 |
| Liu, MY | 1 |
| Drory, Y | 1 |
| Ouaknine, G | 1 |
| Kosary, IZ | 1 |
| Kellermann, JJ | 1 |
| Glista, GG | 1 |
| Mellinger, JF | 1 |
| Rooke, ED | 1 |
| Weiss, HD | 1 |
| Stern, BJ | 1 |
| Goldberg, J | 1 |
| Chioléro, RL | 1 |
| Breitenstein, E | 1 |
| Thorin, D | 1 |
| Christin, L | 1 |
| de Tribolet, N | 1 |
| Freeman, J | 1 |
| Jéquier, E | 1 |
| Schutz, Y | 1 |
| Haas, JF | 1 |
| Cope, DN | 1 |
| Leeman, M | 2 |
| Naeije, R | 2 |
| Degaute, JP | 2 |
| Brackman, F | 2 |
| Prost, JF | 2 |
| Thomas, J | 1 |
| Biary, N | 1 |
| Cleeves, L | 1 |
| Findley, L | 1 |
| Koller, W | 1 |
| Vijayan, N | 1 |
| Dreyfus, PM | 1 |
| Niki, H | 1 |
| Tada, Y | 1 |
| Hinoki, M | 1 |
| Ishida, Y | 1 |
| Ushio, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Controlling Hyperadrenergic Activity in Neurologic Injury[NCT01343329] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2011-07-31 | Withdrawn (stopped due to Unable to enroll subjects that fit study criteria.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for propranolol and Craniocerebral Trauma
| Article | Year |
|---|---|
Acute central and renal haemodynamic responses to tertatolol and propranolol in patients with arterial hypertension following head injury.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Cardiac Output; Craniocerebral Trauma; Female; | 1986 |
12 other studies available for propranolol and Craniocerebral Trauma
| Article | Year |
|---|---|
Hyponatremia as a result of posttraumatic primary polydipsia.
Topics: Adrenergic beta-Antagonists; Antipsychotic Agents; Benzodiazepines; Craniocerebral Trauma; Humans; H | 2015 |
Treatment of hypertension associated with head injury.
Topics: Adolescent; Adult; Craniocerebral Trauma; Epinephrine; Hemodynamics; Humans; Hydralazine; Hypertensi | 1983 |
Protective effects of propranolol on experimentally head-injured mouse brains.
Topics: Adrenergic beta-Antagonists; Animals; Brain; Craniocerebral Trauma; Male; Mice; Mice, Inbred BALB C; | 1995 |
Electrocardiographic findings in brain death; description and presumed mechanism.
Topics: Adolescent; Adult; Aged; Atropine; Brain Death; Brain Neoplasms; Child; Child, Preschool; Craniocere | 1975 |
Familial hemiplegic migraine.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Craniocerebral Trauma; Ergotamines; Female; Hemipl | 1975 |
Post-traumatic migraine: chronic migraine precipitated by minor head or neck trauma.
Topics: Adolescent; Adult; Amitriptyline; Chronic Disease; Craniocerebral Trauma; Female; Humans; Male; Midd | 1991 |
Effects of propranolol on resting metabolic rate after severe head injury.
Topics: Adolescent; Adult; Basal Metabolism; Calorimetry; Catecholamines; Child; Craniocerebral Trauma; Fema | 1989 |
Neuropharmacologic management of behavior sequelae in head injury: a case report.
Topics: Adult; Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Behavior; Craniocerebral Trauma; Human | 1985 |
Tertatolol preserves renal perfusion in patients with arterial hypertension after head injury.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Craniocerebral Trauma; Female; Hemodynamics; H | 1986 |
Post-traumatic tremor.
Topics: Adult; Clonazepam; Consciousness; Craniocerebral Trauma; Electromyography; Female; Humans; Male; Mid | 1989 |
Posttraumatic dysautonomic cephalgia: clinical observations and treatment.
Topics: Adult; Craniocerebral Trauma; Female; Headache; Humans; Male; Middle Aged; Propranolol | 1974 |
[Autonomic nerve disturbances in traumatic cervical vertigo--the role of the sympathetic nervous tension in the development of vertigo].
Topics: Adolescent; Adult; Autonomic Nervous System; Craniocerebral Trauma; Female; Humans; Male; Neck Injur | 1969 |