Page last updated: 2024-11-03

propranolol and Costello Syndrome

propranolol has been researched along with Costello Syndrome in 1 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Costello Syndrome: Rare congenital disorder with multiple anomalies including: characteristic dysmorphic craniofacial features, musculoskeletal abnormalities, neurocognitive delay, and high prevalence of cancer. Germline mutations in H-Ras protein can cause Costello syndrome. Costello syndrome shows early phenotypic overlap with other disorders that involve MAP KINASE SIGNALING SYSTEM (e.g., NOONAN SYNDROME and cardiofaciocutaneous syndrome).

Research Excerpts

ExcerptRelevanceReference

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Levin, MD1
Saitta, SC1
Gripp, KW1
Wenger, TL1
Ganesh, J1
Kalish, JM1
Epstein, MR1
Smith, R1
Czosek, RJ1
Ware, SM1
Goldenberg, P1
Myers, A1
Chatfield, KC1
Gillespie, MJ1
Zackai, EH1
Lin, AE1

Other Studies

1 other study available for propranolol and Costello Syndrome

ArticleYear
Nonreentrant atrial tachycardia occurs independently of hypertrophic cardiomyopathy in RASopathy patients.
    American journal of medical genetics. Part A, 2018, Volume: 176, Issue:8

    Topics: Amiodarone; Arrhythmias, Cardiac; Calcium; Cardiomyopathy, Hypertrophic; Costello Syndrome; Digoxin;

2018