propranolol has been researched along with Cocaine Abuse in 14 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propranolol- vs." | 2.78 | A double blind, placebo-controlled study of the effects of post-retrieval propranolol on reconsolidation of memory for craving and cue reactivity in cocaine dependent humans. ( Baker, NL; Brady, KT; Gray, KM; Hartwell, KJ; Larowe, SD; McRae-Clark, AL; Saladin, ME; Yeatts, SD, 2013) |
| "Propranolol treated subjects had lower cocaine withdrawal symptom severity but otherwise did not differ from placebo treated subjects in any outcome measure." | 2.70 | Effectiveness of propranolol for cocaine dependence treatment may depend on cocaine withdrawal symptom severity. ( Acosta, T; Alterman, AI; Cnaan, A; Cornish, J; Gariti, P; Kampman, KM; Luce, D; Muller, E; Mulvaney, F; O'Brien, C; Poole, S; Volpicelli, JR, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saladin, ME | 1 |
| Gray, KM | 1 |
| McRae-Clark, AL | 1 |
| Larowe, SD | 1 |
| Yeatts, SD | 1 |
| Baker, NL | 1 |
| Hartwell, KJ | 1 |
| Brady, KT | 1 |
| Chopin, MV | 1 |
| Peretti, CS | 1 |
| Gisquet-Verrier, P | 1 |
| Hoffmann, C | 1 |
| Belaïd, A | 1 |
| Chouinard, G | 1 |
| Kelley, BJ | 1 |
| Yeager, KR | 1 |
| Pepper, TH | 1 |
| Bornstein, RA | 1 |
| Beversdorf, DQ | 1 |
| Izquierdo Gómez, MM | 1 |
| Domínguez-Rodríguez, A | 1 |
| Gálvez Rodríguez, M | 1 |
| Marrero Rodríguez, F | 1 |
| Otis, JM | 1 |
| Mueller, D | 1 |
| Vanderschuren, LJ | 1 |
| Beemster, P | 1 |
| Schoffelmeer, AN | 1 |
| Sofuoglu, M | 1 |
| Kosten, TR | 1 |
| Kampman, KM | 3 |
| Dackis, C | 1 |
| Lynch, KG | 1 |
| Pettinati, H | 1 |
| Tirado, C | 1 |
| Gariti, P | 2 |
| Sparkman, T | 1 |
| Atzram, M | 1 |
| O'Brien, CP | 1 |
| Platt, DM | 1 |
| Rowlett, JK | 1 |
| Spealman, RD | 1 |
| Leikin, JB | 1 |
| O'Brien, TP | 1 |
| Pane, MA | 1 |
| Traystman, RJ | 1 |
| Gleason, CA | 1 |
| Volpicelli, JR | 1 |
| Mulvaney, F | 1 |
| Alterman, AI | 1 |
| Cornish, J | 1 |
| Cnaan, A | 1 |
| Poole, S | 1 |
| Muller, E | 1 |
| Acosta, T | 1 |
| Luce, D | 1 |
| O'Brien, C | 1 |
| Knuepfer, MM | 1 |
| Purcell, RM | 1 |
| Gan, Q | 1 |
| Le, KM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-Blind, Placebo Controlled Trial of Propranolol and Amantadine for the Treatment of Cocaine Dependent Subjects With Severe Cocaine Withdrawal Symptoms[NCT00158132] | Phase 2 | 199 participants (Actual) | Interventional | 1999-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for propranolol and Cocaine Abuse
| Article | Year |
|---|---|
Emerging pharmacological strategies in the fight against cocaine addiction.
Topics: Adrenergic beta-Antagonists; Animals; Benzhydryl Compounds; Brain; Central Nervous System Stimulants | 2006 |
Cocaine and beta-adrenergic blockers: a remarriage after a decade-long divorce?
Topics: Adrenergic beta-Antagonists; Animals; Cardiovascular Diseases; Cerebrovascular Disorders; Cocaine-Re | 1999 |
4 trials available for propranolol and Cocaine Abuse
| Article | Year |
|---|---|
A double blind, placebo-controlled study of the effects of post-retrieval propranolol on reconsolidation of memory for craving and cue reactivity in cocaine dependent humans.
Topics: Adrenergic beta-Antagonists; Adult; Cocaine-Related Disorders; Cues; Double-Blind Method; Female; Fo | 2013 |
The effect of propranolol on cognitive flexibility and memory in acute cocaine withdrawal.
Topics: Acute Disease; Adaptation, Psychological; Adrenergic beta-Antagonists; Adult; Cocaine-Related Disord | 2007 |
A double-blind, placebo-controlled trial of amantadine, propranolol, and their combination for the treatment of cocaine dependence in patients with severe cocaine withdrawal symptoms.
Topics: Adrenergic beta-Antagonists; Adult; Amantadine; Analgesics, Non-Narcotic; Cocaine; Cocaine-Related D | 2006 |
Effectiveness of propranolol for cocaine dependence treatment may depend on cocaine withdrawal symptom severity.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Hum | 2001 |
8 other studies available for propranolol and Cocaine Abuse
| Article | Year |
|---|---|
Cocaine Use Disorder Treated with Specific Cognitive Behavioral Therapy and Adjunctive Propranolol.
Topics: Adult; Chemotherapy, Adjuvant; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Cues; Humans | 2016 |
Reflections on beta-adrenergic receptor blockers and cocaine use. A case in point.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Adult; Cocaine-Related Disorders; Electrocardi | 2009 |
Inhibition of β-adrenergic receptors induces a persistent deficit in retrieval of a cocaine-associated memory providing protection against reinstatement.
Topics: Adrenergic beta-Antagonists; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychologica | 2011 |
On the role of noradrenaline in psychostimulant-induced psychomotor activity and sensitization.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Clonidine; Cocaine; Cocai | 2003 |
Noradrenergic mechanisms in cocaine-induced reinstatement of drug seeking in squirrel monkeys.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Addictive; Be | 2007 |
The search for medications to treat stimulant dependence.
Topics: Amphetamine-Related Disorders; Benzhydryl Compounds; Brain; Bupropion; Cocaine; Cocaine-Related Diso | 2008 |
Propranolol blocks cocaine-induced cerebral vasodilation in newborn sheep.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Blood Flow Velocity; Cerebrovascular Circula | 1999 |
Hemodynamic response patterns to acute behavioral stressors resemble those to cocaine.
Topics: Acute Disease; Analysis of Variance; Animals; Blood Pressure; Cardiac Output; Cocaine-Related Disord | 2001 |