propranolol has been researched along with Chronic Lung Injury in 12 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using a clinically relevant rodent model of lung contusion (LC), hemorrhagic shock (HS), and chronic stress (CS), we hypothesize that daily propranolol (BB), a nonselective β blocker, restores BM function and improves iron homeostasis." | 7.85 | Daily propranolol administration reduces persistent injury-associated anemia after severe trauma and chronic stress. ( Alamo, IG; Bible, LE; Efron, PA; Kannan, KB; Loftus, TJ; Mohr, AM; Ramos, H, 2017) |
| "The daily administration of propranolol after both lung contusion and lung contusion/hemorrhagic shock subjected to chronic restraint stress decreased the prolonged mobilization of HPC from the bone marrow and decreased plasma G-CSF levels." | 7.81 | Daily propranolol prevents prolonged mobilization of hematopoietic progenitor cells in a rat model of lung contusion, hemorrhagic shock, and chronic stress. ( Bible, LE; Gore, AV; Kannan, KB; Mohr, AM; Pasupuleti, LV; Sifri, ZC, 2015) |
| "Male Sprague-Dawley rats aged 8 to 9 weeks were randomized to lung contusion, hemorrhagic shock with daily restraint stress (LCHS/CS) or LCHS/CS plus propranolol (LCHS/CS+BB)." | 3.96 | Effect of Beta-Blockade on the Expression of Regulatory MicroRNA after Severe Trauma and Chronic Stress. ( Apple, CG; Baker, HV; Efron, PA; Kannan, KB; Loftus, TJ; Lopez, MC; Miller, ES; Mohr, AM; Moldawer, LL; Thompson, CW, 2020) |
| "Male Sprague-Dawley rats were allocated to naïve control, lung contusion followed by hemorrhagic shock (LCHS), or LCHS plus daily chronic restraint stress (LCHS/CS) ±propranolol, ±clonidine." | 3.91 | The effects of propranolol and clonidine on bone marrow expression of hematopoietic cytokines following trauma and chronic stress. ( Alamo, IG; Efron, PA; Kannan, KB; Loftus, TJ; Millar, JK; Miller, ES; Mohr, AM, 2019) |
| "Clonidine increased VEGF and VEGF-receptor expression, decreased HMGB1 expression, decreased lung inflammation, and improved lung tissue repair." | 3.85 | Clonidine restores vascular endothelial growth factor expression and improves tissue repair following severe trauma. ( Alamo, IG; Efron, PA; Kannan, KB; Loftus, TJ; Millar, JK; Mohr, AM; Plazas, JM; Thomson, AJ; Whitley, EE, 2017) |
| " Using a clinically relevant rodent model of lung contusion (LC), hemorrhagic shock (HS), and chronic stress (CS), we hypothesize that daily propranolol (BB), a nonselective β blocker, restores BM function and improves iron homeostasis." | 3.85 | Daily propranolol administration reduces persistent injury-associated anemia after severe trauma and chronic stress. ( Alamo, IG; Bible, LE; Efron, PA; Kannan, KB; Loftus, TJ; Mohr, AM; Ramos, H, 2017) |
| "The daily administration of propranolol after both lung contusion and lung contusion/hemorrhagic shock subjected to chronic restraint stress decreased the prolonged mobilization of HPC from the bone marrow and decreased plasma G-CSF levels." | 3.81 | Daily propranolol prevents prolonged mobilization of hematopoietic progenitor cells in a rat model of lung contusion, hemorrhagic shock, and chronic stress. ( Bible, LE; Gore, AV; Kannan, KB; Mohr, AM; Pasupuleti, LV; Sifri, ZC, 2015) |
| "Propranolol was administered daily." | 1.62 | Mediators of Prolonged Hematopoietic Progenitor Cell Mobilization After Severe Trauma. ( Apple, CG; Doobay, GD; Efron, PA; Kannan, KB; Loftus, TJ; Miller, ES; Mohr, AM, 2021) |
| "Propranolol has been shown to improve erythroid progenitor cell growth and anemia following trauma and this study sought to investigate the mechanisms involved by evaluating the effects of selective beta blockade." | 1.56 | The effects of selective beta-adrenergic blockade on bone marrow dysfunction following severe trauma and chronic stress. ( Apple, CG; Efron, PA; Funk, ZM; Kannan, KB; Miller, ES; Mohr, AM, 2020) |
| "Villous injury and lung injury were graded histologically by a blinded reader." | 1.38 | Is the sympathetic system involved in shock-induced gut and lung injury? ( Alzate, WD; Baranski, GM; Cook, KM; Livingston, DH; Mohr, AM; Sifri, ZC, 2012) |
| "Propranolol (10 mg/kg) was given once the mean arterial blood pressure>80 mm Hg and subsequent doses were given daily (LC/HS/BB)." | 1.37 | Does beta blockade postinjury prevent bone marrow suppression? ( Alzate, WD; ElHassan, IO; Hannoush, EJ; Livingston, DH; Mohr, AM; Offin, MD; Rameshwar, P; Sifri, ZC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Apple, CG | 3 |
| Miller, ES | 4 |
| Loftus, TJ | 5 |
| Kannan, KB | 7 |
| Thompson, CW | 1 |
| Lopez, MC | 1 |
| Baker, HV | 1 |
| Moldawer, LL | 1 |
| Efron, PA | 6 |
| Mohr, AM | 9 |
| Funk, ZM | 1 |
| Doobay, GD | 1 |
| Thomson, AJ | 1 |
| Alamo, IG | 3 |
| Millar, JK | 2 |
| Plazas, JM | 1 |
| Whitley, EE | 1 |
| Zhou, Y | 1 |
| Xu, M | 1 |
| Zhang, Y | 2 |
| Guo, Y | 1 |
| He, B | 1 |
| Bible, LE | 2 |
| Pasupuleti, LV | 1 |
| Gore, AV | 1 |
| Sifri, ZC | 3 |
| Ramos, H | 1 |
| ElHassan, IO | 1 |
| Hannoush, EJ | 1 |
| Offin, MD | 1 |
| Alzate, WD | 2 |
| Rameshwar, P | 1 |
| Livingston, DH | 2 |
| Baranski, GM | 1 |
| Cook, KM | 1 |
| Smith, DM | 1 |
| Smith, SK | 1 |
| Merker, MP | 1 |
| Gillis, CN | 1 |
12 other studies available for propranolol and Chronic Lung Injury
| Article | Year |
|---|---|
Effect of Beta-Blockade on the Expression of Regulatory MicroRNA after Severe Trauma and Chronic Stress.
Topics: Adrenergic beta-Antagonists; Animals; Chronic Disease; Contusions; Injury Severity Score; Lung Injur | 2020 |
The effects of selective beta-adrenergic blockade on bone marrow dysfunction following severe trauma and chronic stress.
Topics: Adrenergic beta-Antagonists; Animals; Biomarkers; Bone Marrow; Contusions; Lung Injury; Male; Propra | 2020 |
Mediators of Prolonged Hematopoietic Progenitor Cell Mobilization After Severe Trauma.
Topics: Adrenergic beta-Antagonists; Animals; Biomarkers; Bone Marrow; Chronic Disease; Contusions; Enzyme-L | 2021 |
Clonidine restores vascular endothelial growth factor expression and improves tissue repair following severe trauma.
Topics: Animals; Clonidine; HMGB1 Protein; Inflammation; Lung Injury; Propranolol; Pulmonary Edema; Rats; Ra | 2017 |
The effects of propranolol and clonidine on bone marrow expression of hematopoietic cytokines following trauma and chronic stress.
Topics: Anemia; Animals; Biomarkers; Bone Marrow; Chronic Disease; Clonidine; Contusions; Cytokines; Drug Th | 2019 |
Effects of long-term application of metoprolol and propranolol in a rat model of smoking.
Topics: Adrenergic beta-Antagonists; Animals; Bronchoalveolar Lavage Fluid; Interleukin-8; Lung; Lung Injury | 2014 |
Daily propranolol prevents prolonged mobilization of hematopoietic progenitor cells in a rat model of lung contusion, hemorrhagic shock, and chronic stress.
Topics: Adrenergic beta-Antagonists; Animals; Biomarkers; Chemokine CXCL12; Contusions; Drug Administration | 2015 |
Daily propranolol administration reduces persistent injury-associated anemia after severe trauma and chronic stress.
Topics: Anemia; Animals; Bone Marrow; Contusions; Disease Models, Animal; Lung Injury; Male; Propranolol; Ra | 2017 |
Does beta blockade postinjury prevent bone marrow suppression?
Topics: Adrenergic beta-Antagonists; Animals; Bone Marrow; Bone Marrow Diseases; Cells, Cultured; Disease Mo | 2011 |
Is the sympathetic system involved in shock-induced gut and lung injury?
Topics: Adrenergic beta-Antagonists; Animals; Bone Marrow Cells; Cells, Cultured; Disease Models, Animal; Ga | 2012 |
The fibrogenic response of adult rat lung to continuous propranolol treatment.
Topics: Animals; Lung; Lung Injury; Male; Microscopy, Electron; Propranolol; Pulmonary Fibrosis; Rats; Rats, | 1988 |
Propranolol and serotonin removal in lung injury.
Topics: Animals; In Vitro Techniques; Indicator Dilution Techniques; Lung; Lung Injury; Male; Papaverine; Pe | 1988 |