propranolol and Cholestasis
propranolol has been researched along with Cholestasis in 7 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Consumptive hypothyroidism is a rare paraneoplastic syndrome characterized by excessive inactivation of the thyroid hormones due to increased type 3 iodothyronine deiodinase activity of tumors." | 1.56 | A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas. ( Hong, KT; Kim, GB; Kim, YH; Ko, JS; Lee, YA; Lee, YJ; Shin, CH, 2020) |
"Treatment with methimazole resolved the hyperthyroidism, and the cholestasis improved, as well." | 1.38 | Graves' disease presenting with severe cholestasis. ( Arnon, R; Kerkar, N; Miloh, T; Morotti, R; Rapaport, R; Regelmann, MO, 2012) |
" Our aim was to study the hemodynamic effects of the early and chronic administration of PR and spironolactone (SPN), alone or in combination, in a model of hepatic fibrosis and sinusoidal portal hypertension induced in rats by bile duct ligation." | 1.30 | Prevention of portal hypertension by propranolol and spironolactone in rats with bile duct ligation. ( Calès, P; Douay, O; Gallois, Y; Le Jeune, JJ; Maïga, MY; Oberti, F; Pilette, C; Rifflet, H; Saumet, JL, 1997) |
"Propranolol pretreatment (30 min prior to phalloidin injection) did not afford protection against hepatotoxicity, but increased alkaline phosphatase, 5'-nucleotidase and aminotransferase activities." | 1.26 | Phalloidin hepatotoxicity in rats in vivo. Effect of a sympatholytic agent: propranolol. ( Claude, JR; Jacqueson, A; Thevenin, M; Warnet, JM, 1981) |
" Patients with cirrhosis had a significantly longer quinidine half-life (9 +/- 1 hr; p less than ." | 1.26 | Quinidine pharmacokinetics in patients with cirrhosis or receiving propranolol. ( Black, M; Humphries, WC; Kessler, KM; Spann, JF, 1978) |
Research
Studies (7)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (28.57) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 1 (14.29) | 29.6817 |
2010's | 2 (28.57) | 24.3611 |
2020's | 1 (14.29) | 2.80 |
Authors
Authors | Studies |
---|---|
Dawson, S | 1 |
Stahl, S | 1 |
Paul, N | 1 |
Barber, J | 1 |
Kenna, JG | 1 |
Kim, YH | 1 |
Lee, YA | 1 |
Shin, CH | 1 |
Hong, KT | 1 |
Kim, GB | 1 |
Ko, JS | 1 |
Lee, YJ | 1 |
Regelmann, MO | 1 |
Miloh, T | 1 |
Arnon, R | 1 |
Morotti, R | 1 |
Kerkar, N | 1 |
Rapaport, R | 1 |
Soysal, D | 1 |
Tatar, E | 1 |
Solmaz, S | 1 |
Kabayeğit, O | 1 |
Tunakan, M | 1 |
Unsal, B | 1 |
Cevik, C | 1 |
Thevenin, M | 1 |
Warnet, JM | 1 |
Jacqueson, A | 1 |
Claude, JR | 1 |
Oberti, F | 1 |
Rifflet, H | 1 |
Maïga, MY | 1 |
Pilette, C | 1 |
Gallois, Y | 1 |
Douay, O | 1 |
Le Jeune, JJ | 1 |
Saumet, JL | 1 |
Calès, P | 1 |
Kessler, KM | 1 |
Humphries, WC | 1 |
Black, M | 1 |
Spann, JF | 1 |
Other Studies
7 other studies available for propranolol and Cholestasis
Article | Year |
---|---|
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas.
Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Cholestasis; Drug Therapy, Combination; Heart | 2020 |
Graves' disease presenting with severe cholestasis.
Topics: Adolescent; Adrenergic beta-Antagonists; Antithyroid Agents; Bilirubin; Cholestasis; Female; Graves | 2012 |
A case of severe cholestatic jaundice associated with Graves' disease.
Topics: Adrenergic beta-Antagonists; Antithyroid Agents; Cholangiopancreatography, Magnetic Resonance; Chole | 2008 |
Phalloidin hepatotoxicity in rats in vivo. Effect of a sympatholytic agent: propranolol.
Topics: Animals; Bile; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Lipid Metabolism; Liver; | 1981 |
Prevention of portal hypertension by propranolol and spironolactone in rats with bile duct ligation.
Topics: Animals; Antihypertensive Agents; Cholestasis; Drug Evaluation, Preclinical; Drug Therapy, Combinati | 1997 |
Quinidine pharmacokinetics in patients with cirrhosis or receiving propranolol.
Topics: Adult; Aged; Blood Proteins; Cholestasis; Drug Interactions; Female; Half-Life; Humans; Intestinal A | 1978 |