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propranolol and Cholestasis

propranolol has been researched along with Cholestasis in 7 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Research Excerpts

ExcerptRelevanceReference
"Consumptive hypothyroidism is a rare paraneoplastic syndrome characterized by excessive inactivation of the thyroid hormones due to increased type 3 iodothyronine deiodinase activity of tumors."1.56A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas. ( Hong, KT; Kim, GB; Kim, YH; Ko, JS; Lee, YA; Lee, YJ; Shin, CH, 2020)
"Treatment with methimazole resolved the hyperthyroidism, and the cholestasis improved, as well."1.38Graves' disease presenting with severe cholestasis. ( Arnon, R; Kerkar, N; Miloh, T; Morotti, R; Rapaport, R; Regelmann, MO, 2012)
" Our aim was to study the hemodynamic effects of the early and chronic administration of PR and spironolactone (SPN), alone or in combination, in a model of hepatic fibrosis and sinusoidal portal hypertension induced in rats by bile duct ligation."1.30Prevention of portal hypertension by propranolol and spironolactone in rats with bile duct ligation. ( Calès, P; Douay, O; Gallois, Y; Le Jeune, JJ; Maïga, MY; Oberti, F; Pilette, C; Rifflet, H; Saumet, JL, 1997)
"Propranolol pretreatment (30 min prior to phalloidin injection) did not afford protection against hepatotoxicity, but increased alkaline phosphatase, 5'-nucleotidase and aminotransferase activities."1.26Phalloidin hepatotoxicity in rats in vivo. Effect of a sympatholytic agent: propranolol. ( Claude, JR; Jacqueson, A; Thevenin, M; Warnet, JM, 1981)
" Patients with cirrhosis had a significantly longer quinidine half-life (9 +/- 1 hr; p less than ."1.26Quinidine pharmacokinetics in patients with cirrhosis or receiving propranolol. ( Black, M; Humphries, WC; Kessler, KM; Spann, JF, 1978)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Dawson, S1
Stahl, S1
Paul, N1
Barber, J1
Kenna, JG1
Kim, YH1
Lee, YA1
Shin, CH1
Hong, KT1
Kim, GB1
Ko, JS1
Lee, YJ1
Regelmann, MO1
Miloh, T1
Arnon, R1
Morotti, R1
Kerkar, N1
Rapaport, R1
Soysal, D1
Tatar, E1
Solmaz, S1
Kabayeğit, O1
Tunakan, M1
Unsal, B1
Cevik, C1
Thevenin, M1
Warnet, JM1
Jacqueson, A1
Claude, JR1
Oberti, F1
Rifflet, H1
Maïga, MY1
Pilette, C1
Gallois, Y1
Douay, O1
Le Jeune, JJ1
Saumet, JL1
Calès, P1
Kessler, KM1
Humphries, WC1
Black, M1
Spann, JF1

Other Studies

7 other studies available for propranolol and Cholestasis

ArticleYear
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas.
    Journal of Korean medical science, 2020, Jun-08, Volume: 35, Issue:22

    Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Cholestasis; Drug Therapy, Combination; Heart

2020
Graves' disease presenting with severe cholestasis.
    Thyroid : official journal of the American Thyroid Association, 2012, Volume: 22, Issue:4

    Topics: Adolescent; Adrenergic beta-Antagonists; Antithyroid Agents; Bilirubin; Cholestasis; Female; Graves

2012
A case of severe cholestatic jaundice associated with Graves' disease.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2008, Volume: 19, Issue:1

    Topics: Adrenergic beta-Antagonists; Antithyroid Agents; Cholangiopancreatography, Magnetic Resonance; Chole

2008
Phalloidin hepatotoxicity in rats in vivo. Effect of a sympatholytic agent: propranolol.
    Toxicology letters, 1981, Volume: 7, Issue:6

    Topics: Animals; Bile; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Lipid Metabolism; Liver;

1981
Prevention of portal hypertension by propranolol and spironolactone in rats with bile duct ligation.
    Journal of hepatology, 1997, Volume: 26, Issue:1

    Topics: Animals; Antihypertensive Agents; Cholestasis; Drug Evaluation, Preclinical; Drug Therapy, Combinati

1997
Quinidine pharmacokinetics in patients with cirrhosis or receiving propranolol.
    American heart journal, 1978, Volume: 96, Issue:5

    Topics: Adult; Aged; Blood Proteins; Cholestasis; Drug Interactions; Female; Half-Life; Humans; Intestinal A

1978
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