Page last updated: 2024-11-03

propranolol and Chemical Dependence

propranolol has been researched along with Chemical Dependence in 57 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"Delirium in 3 elderly patients with recent cerebral infarction and pre-existing brain dysfunction receiving low dose propranolol is described."7.69Low dose propranolol-induced delirium: 3 cases report and a review of literature. ( Chang, YY; Chen, WH; Liu, JS, 1994)
"On 51 of 53 occasions, sudden withdrawal of propranolol from patients with angina pectoris produced no substantial adverse effects."7.65Sudden withdrawal of propranolol in patients with angina pectoris. ( Myers, MG; Wisenberg, G, 1977)
" Clinically, propranolol, an agent of this group, has been investigated in the treatment of various clinical disorders including schizophrenia, other psychoses, anxiety disorders, and stress reactions."6.15Propranolol in psychiatry. Therapeutic uses and side effects. ( Ananth, J; Lin, KM, 1986)
"Both patients experienced generalized seizures and had a transient intraventricular conduction defect on electrocardiogram."5.26Seizures and intraventricular conduction defect in propranolol poisoning. A report of two cases. ( Bock, J; Buiumsohn, A; Eisenberg, ES; Frishman, WH; Jacob, H; Rosen, N, 1979)
"Delirium in 3 elderly patients with recent cerebral infarction and pre-existing brain dysfunction receiving low dose propranolol is described."3.69Low dose propranolol-induced delirium: 3 cases report and a review of literature. ( Chang, YY; Chen, WH; Liu, JS, 1994)
"On 51 of 53 occasions, sudden withdrawal of propranolol from patients with angina pectoris produced no substantial adverse effects."3.65Sudden withdrawal of propranolol in patients with angina pectoris. ( Myers, MG; Wisenberg, G, 1977)
"Barbital was applied on a schedule of gradually increasing dosages from 0."1.27Effects of propranolol on barbital dependence formation and withdrawal signs. ( Hiramori, T; Nakao, K; Tagashira, E; Urano, T; Yanaura, S, 1983)
" These patients are best managed as outpatients with gradual dosage reduction over 4-12 weeks."1.27Management of benzodiazepine dependence. ( Lader, M; Moodley, P, 1986)
"Both patients experienced generalized seizures and had a transient intraventricular conduction defect on electrocardiogram."1.26Seizures and intraventricular conduction defect in propranolol poisoning. A report of two cases. ( Bock, J; Buiumsohn, A; Eisenberg, ES; Frishman, WH; Jacob, H; Rosen, N, 1979)
"The ventricular arrhythmias caused in well oxygenated monkeys by fluoroalkane gases may either be mediated through beta adrenergic receptors, since propranolol abolished these arrhythmias, or result from a nonadrenergic, direct, toxic effect of these gases on the heart."1.25Ventricular arrhythmias induced in monkeys by the inhalation of aerosol propellants. ( Bogdonoff, MD; Harris, WS; Taylor, GJ, 1971)

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-199047 (82.46)18.7374
1990's4 (7.02)18.2507
2000's2 (3.51)29.6817
2010's4 (7.02)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ronan, GP1
Ronan, N1
McGettigan, S1
Browne, G1
Cummins Jacklin, E1
Boughner, E1
Kent, K1
Kwiatkowski, D1
MacDonald, T1
Leri, F1
Lonergan, M1
Saumier, D1
Tremblay, J1
Kieffer, B1
Brown, TG1
Brunet, A1
Mao, Y1
Yang, SC1
Liu, C1
Ma, YY1
Hu, XT1
Sugiyama, T1
Fontanella, BJ1
Obukhov, GA1
Peet, M1
Urquhart, J1
Fara, JW1
Willis, KL1
Mittleman, HS1
Mittleman, RE1
Elser, B1
Tagashira, E1
Hiramori, T1
Urano, T1
Nakao, K1
Yanaura, S1
Gay, GR1
Abrams, J1
Tikare, SK1
Bandisode, MS1
Waddingham, S2
Belknap, JK2
Collier, HO1
Cuthbert, NJ1
Francis, DL1
Harris, GC1
Aston-Jones, G1
Chen, WH1
Liu, JS1
Chang, YY1
Berkowitz, BA1
Snyder, SH1
Resnick, RB1
Kestenbaum, RS1
Schwartz, LK2
Smith, A1
Swartz, C1
Riffee, WR1
Sheppard, JR1
Buiumsohn, A1
Eisenberg, ES1
Jacob, H1
Rosen, N1
Bock, J1
Frishman, WH1
Myers, MG1
Wisenberg, G1
Klimek, A2
Poźniak-Patewicz, E2
Rappolt, RT1
Gray, GR1
Inaba, DS1
Simpson, LL1
Jacob, RG1
Holmstrand, J1
Eriksson, JH1
Anggård, E1
Retterstol, N1
Hage, J1
Jensen, K1
Aviado, DM1
Smith, DE1
Landry, MJ1
Cantopher, T1
Cleave, N1
Edwards, G1
Olivieri, S1
Weinstein, RS1
Cole, S1
Knaster, HB1
Dahlbert, T1
Noyes, R1
Lasek, R1
Müller, M1
Lennane, KJ1
Crouch, G2
Robson, M2
Hallstrom, C2
Shine, P1
Moodley, P2
Araya, R1
Gwinup, GR1
Ananth, J1
Lin, KM1
Kaneto, H1
Kaneda, H1
Kawatani, S1
Lader, M1
Silverstein, W1
Lewin, NA1
Goldfrank, L1
Taylor, GJ1
Harris, WS1
Bogdonoff, MD1
Grosz, HJ3
Lowenstein, H1
Whitlock, FA1
Price, J1
Beaconsfield, P1
Ginsburg, J1
Rainsbury, R1
Friedman, AP1
Kersh, ES1
Castan, R1

Reviews

13 reviews available for propranolol and Chemical Dependence

ArticleYear
[Benzodiazepine-related disorders].
    Ryoikibetsu shokogun shirizu, 2003, Issue:40

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Benzodiazepines; Cognitive Behavioral

2003
[Use of beta-adrenergic blockers in neurologic and psychiatric clinical practice].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:5

    Topics: Adrenergic beta-Antagonists; Alcoholism; Anti-Anxiety Agents; Cardiovascular Diseases; Humans; Hyper

1981
Rate-controlled delivery systems in drug and hormone research.
    Annual review of pharmacology and toxicology, 1984, Volume: 24

    Topics: Animals; Antihypertensive Agents; Circadian Rhythm; Drug Implants; Drug Tolerance; Drug-Related Side

1984
Clinical management of acute and chronic cocaine poisoning.
    Annals of emergency medicine, 1982, Volume: 11, Issue:10

    Topics: Brain; California; Cardiovascular System; Chemical Phenomena; Chemistry; Cocaine; Diazepam; Humans;

1982
Nitrate tolerance and dependence.
    American heart journal, 1980, Volume: 99, Issue:1

    Topics: Ambulatory Care; Angina Pectoris; Animals; Cardiovascular Diseases; Dogs; Drug Tolerance; Heart Fail

1980
The relationship of pharmacokinetics to pharmacological activity: morphine, methadone and naloxone.
    Clinical pharmacokinetics, 1976, Volume: 1, Issue:3

    Topics: Absorption; Aging; Aspirin; Blood Proteins; Dose-Response Relationship, Drug; Drug Interactions; Fem

1976
Receptors, neurotransmitters and drug responses.
    The New England journal of medicine, 1979, Mar-01, Volume: 300, Issue:9

    Topics: Animals; Antipsychotic Agents; Behavior; Brain Chemistry; Cyclic AMP; Dyskinesia, Drug-Induced; Enke

1979
Benzodiazepine dependency discontinuation: focus on the chemical dependency detoxification setting and benzodiazepine-polydrug abuse.
    Journal of psychiatric research, 1990, Volume: 24 Suppl 2

    Topics: Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Drug Administration Schedule

1990
Beta-adrenergic blocking drugs in anxiety and stress.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Asthma; Benzodiazepine

1985
Treatment of benzodiazepine dependence.
    The Medical journal of Australia, 1986, May-26, Volume: 144, Issue:11

    Topics: Aged; Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Cats; Drug Tolerance; Epilepsy; Female

1986
[Practical aspects of the clinical management of benzodiazepine dependence].
    Revista medica de Chile, 1988, Volume: 116, Issue:5

    Topics: Antipsychotic Agents; Benzodiazepines; Clonixin; Humans; Propranolol; Psychotherapy; Substance Withd

1988
Propranolol in psychiatry. Therapeutic uses and side effects.
    Neuropsychobiology, 1986, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Anxiety Disorders; Central Nervous System Diseases; Child; Clinical Trials as Top

1986
Use of beta-adrenergic receptor blocking drugs in psychiatry.
    Drugs, 1974, Volume: 8, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Anxiety; Chlordiazepoxide; Di

1974

Trials

8 trials available for propranolol and Chemical Dependence

ArticleYear
Reactivating addiction-related memories under propranolol to reduce craving: A pilot randomized controlled trial.
    Journal of behavior therapy and experimental psychiatry, 2016, Volume: 50

    Topics: Adolescent; Adult; Aged; Craving; Double-Blind Method; Female; Humans; Male; Mental Recall; Middle A

2016
Evaluation of propranolol in opiate dependence.
    Archives of general psychiatry, 1976, Volume: 33, Issue:8

    Topics: Adult; Clinical Trials as Topic; Heroin; Heroin Dependence; Humans; Hydromorphone; Male; Propranolol

1976
Propranolol in the treatment of opiate dependence -- a controlled study.
    Psychopharmacologia, 1975, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Clinical Trials as Topic; Euphoria; Female; Heart Rate; Humans; Male; Methadone;

1975
Beta-adrenergic blocking drugs in anxiety and stress.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Asthma; Benzodiazepine

1985
The treatment of tranquilizer dependence by propranolol.
    Postgraduate medical journal, 1988, Volume: 64 Suppl 2

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Female;

1988
Propranolol in psychiatry. Therapeutic uses and side effects.
    Neuropsychobiology, 1986, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Anxiety Disorders; Central Nervous System Diseases; Child; Clinical Trials as Top

1986
Narcotic withdrawal symptoms in heroin users treated with propranolol.
    Lancet (London, England), 1972, Sep-16, Volume: 2, Issue:7777

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Female; Heroin; Hu

1972
Effect of propranolol on active users of heroin.
    Lancet (London, England), 1973, Sep-15, Volume: 2, Issue:7829

    Topics: Adult; Clinical Trials as Topic; Heroin; Heroin Dependence; Humans; Placebos; Propranolol; Substance

1973

Other Studies

38 other studies available for propranolol and Chemical Dependence

ArticleYear
Serotonin syndrome unmasking thyrotoxicosis.
    BMJ case reports, 2019, Mar-07, Volume: 12, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Aftercare; Anti-Arrhythmia Agents; Antithyroid Agents; Carbima

2019
Memory of a drug lapse: Role of noradrenaline.
    Neuropharmacology, 2015, Volume: 99

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Animals; Basolateral

2015
[Effects of propranolol on acquisition and retrieval of morphine- induced conditioned place preference memories in ICR mice].
    Dong wu xue yan jiu = Zoological research, 2011, Volume: 32, Issue:6

    Topics: Animals; Conditioning, Psychological; Extinction, Psychological; Humans; Male; Memory; Mice; Mice, I

2011
[Social anxiety and propranolol abuse: a case study].
    Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2003, Volume: 25, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; F

2003
Beta-blockade in anxiety.
    Postgraduate medical journal, 1984, Volume: 60 Suppl 2

    Topics: Adrenergic beta-Antagonists; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Humans; Oxpren

1984
Cocaine.
    The American journal of nursing, 1984, Volume: 84, Issue:9

    Topics: Cocaine; Emergencies; Fever; Humans; Hypertension; Propranolol; Seizures; Substance-Related Disorder

1984
Effects of propranolol on barbital dependence formation and withdrawal signs.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:1

    Topics: Animals; Anticonvulsants; Barbital; Barbiturates; Drug Interactions; Humans; Male; Propranolol; Rats

1983
Central nervous system side effects of propranolol.
    Journal of the Medical Association of Georgia, 1982, Volume: 71, Issue:11

    Topics: Aged; Delusions; Dreams; Hallucinations; Humans; Male; Propranolol; Substance-Related Disorders

1982
Barbiturate dependence in mice: effects of propranolol on the withdrawal syndrome.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1980, Volume: 163, Issue:4

    Topics: Animals; Barbiturates; Disease Models, Animal; Humans; Isomerism; Male; Mice; Mice, Inbred C57BL; Pr

1980
Clonidine dependence in the guinea-pig isolated ileum.
    British journal of pharmacology, 1981, Volume: 73, Issue:2

    Topics: Animals; Clonidine; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Morphine Derivatives; Mus

1981
Beta-adrenergic antagonists attenuate withdrawal anxiety in cocaine- and morphine-dependent rats.
    Psychopharmacology, 1993, Volume: 113, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Anxiety; Atenolol; Cocaine; Injections, Intraperitoneal; Male;

1993
Low dose propranolol-induced delirium: 3 cases report and a review of literature.
    Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences, 1994, Volume: 10, Issue:1

    Topics: Aged; Delirium; Electrocardiography; Female; Humans; Male; Propranolol; Substance-Related Disorders

1994
Propranolol abuse or performer's maturation?
    Lancet (London, England), 1978, Nov-18, Volume: 2, Issue:8099

    Topics: Fear; Humans; Music; Panic; Propranolol; Stress, Psychological; Substance-Related Disorders

1978
Barbiturate dependence in mice: evidence for beta-adrenergic receptor proliferation in brain.
    Research communications in chemical pathology and pharmacology, 1978, Volume: 20, Issue:2

    Topics: Alprenolol; Animals; Barbiturates; Brain; Cell Membrane; Cerebral Cortex; Humans; Mice; Mice, Inbred

1978
Seizures and intraventricular conduction defect in propranolol poisoning. A report of two cases.
    Annals of internal medicine, 1979, Volume: 91, Issue:6

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Bradycardia; Female; Humans; Propranolol; Seizures; Substan

1979
Sudden withdrawal of propranolol in patients with angina pectoris.
    Chest, 1977, Volume: 71, Issue:1

    Topics: Adult; Aged; Angina Pectoris; Cardiovascular Diseases; Coronary Disease; Female; Humans; Male; Middl

1977
The phenomenon of "drug dependency" in the treatment of migraine with propranolol.
    Headache, 1977, Volume: 17, Issue:2

    Topics: Adult; Female; Humans; Migraine Disorders; Propranolol; Substance-Related Disorders

1977
[Drug dependence in propranolol treatment of migraine].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1977, May-15, Volume: 30, Issue:10

    Topics: Female; Humans; Migraine Disorders; Propranolol; Substance-Related Disorders

1977
Letter: Propranolol in the treatment of cardiopressor effects of cocaine.
    The New England journal of medicine, 1976, 08-19, Volume: 295, Issue:8

    Topics: Cocaine; Humans; Hypertension; Propranolol; Substance-Related Disorders; Tachycardia

1976
The effect of behavioral stimulant doses of amphetamine on blood pressure.
    Archives of general psychiatry, 1976, Volume: 33, Issue:6

    Topics: Amphetamine; Animals; Blood Pressure; Drug Interactions; Humans; Male; Motor Activity; Norepinephrin

1976
[Propranolol in treatment of opiate drug addicts].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Sep-10, Volume: 95, Issue:25

    Topics: Humans; Opium; Propranolol; Substance-Related Disorders

1975
[Propranolol in the treatment of withdrawal symptoms].
    Ugeskrift for laeger, 1975, Mar-10, Volume: 137, Issue:11

    Topics: Adult; Alcoholism; Female; Humans; Male; Propranolol; Substance Withdrawal Syndrome; Substance-Relat

1975
Drug action, reaction, and interaction. II. Iatrogenic cardiopathies.
    Journal of clinical pharmacology, 1975, Volume: 15, Issue:10

    Topics: Anesthetics; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Arrhythmias, Cardiac; Barbit

1975
Benzodiazepine withdrawal.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 157

    Topics: Anti-Anxiety Agents; Benzodiazepines; Humans; Propranolol; Substance Withdrawal Syndrome; Substance-

1990
Beta blocker overdose with propranolol and with atenolol.
    Annals of emergency medicine, 1985, Volume: 14, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Female; Glucagon; Humans; Poisoning; Propr

1985
[The neuropharmacology of beta adrenolytics].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1985, Volume: 37, Issue:7

    Topics: Adrenergic beta-Agonists; Animals; Brain; Epilepsy; Humans; Mental Disorders; Migraine Disorders; Ne

1985
Benzodiazepine dependent patients and their psychological treatment.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12, Issue:4

    Topics: Adaptation, Psychological; Adult; Anti-Anxiety Agents; Behavior Therapy; Combined Modality Therapy;

1988
Propranolol toxicity presenting with early repolarization, ST segment elevation, and peaked T waves on the ECG.
    Annals of emergency medicine, 1988, Volume: 17, Issue:2

    Topics: Bradycardia; Charcoal; Citrates; Citric Acid; Electrocardiography; Humans; Male; Middle Aged; Propra

1988
Pharmacological characterization of alcohol and barbital physical dependence in mice.
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1987, Volume: 7, Issue:2

    Topics: Animals; Atropine; Barbital; Barbiturates; Clonidine; Ethanol; Male; Mice; Muscimol; Propranolol; Su

1987
Management of benzodiazepine dependence.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1986, Apr-26, Volume: 69, Issue:9

    Topics: Barbiturates; Benzodiazepines; Clonidine; Humans; Prognosis; Propranolol; Substance Withdrawal Syndr

1986
Management of the cocaine-intoxicated patient.
    Annals of emergency medicine, 1987, Volume: 16, Issue:2

    Topics: Cocaine; Humans; Hypertension; Propranolol; Substance-Related Disorders

1987
Ventricular arrhythmias induced in monkeys by the inhalation of aerosol propellants.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:7

    Topics: Aerosols; Alkanes; Animals; Arrhythmias, Cardiac; Carbon Dioxide; Cardiac Complexes, Premature; Elec

1971
Propranolol as a psychotropic agent.
    Lancet (London, England), 1973, Mar-10, Volume: 1, Issue:7802

    Topics: Adolescent; Adult; Aged; Female; Humans; Mental Disorders; Propranolol; Substance Withdrawal Syndrom

1973
Marihuana smoking. Cardiovascular effects in man and possible mechanisms.
    The New England journal of medicine, 1972, Aug-03, Volume: 287, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Anesthetics; Atropine; Blood Circulation; Blood Pressure; Cannab

1972
Reflections on the treatment of headache.
    Headache, 1972, Volume: 11, Issue:4

    Topics: Animals; Aspirin; Cyproheptadine; Ergotamine; Haplorhini; Headache; Hormones; Humans; Methysergide;

1972
Successful treatment of a heroin addict with propranolol: implications for opiate addiction, treatment and research.
    The Journal of the Indiana State Medical Association, 1972, Volume: 65, Issue:6

    Topics: Adult; Heroin; Humans; Male; Propranolol; Research; Substance-Related Disorders

1972
Narcotic poisoning: an epidemic disease.
    American family physician, 1973, Volume: 8, Issue:6

    Topics: Diazepam; Glucose; Hospitalization; Humans; Hyperglycemia; Methadone; Myelitis, Transverse; Myoglobi

1973
[Clinical use of propranolol].
    L'union medicale du Canada, 1974, Volume: 103, Issue:8

    Topics: Alcoholism; Angina Pectoris; Aortic Aneurysm; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flut

1974