propranolol has been researched along with Chagas Disease in 16 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chagas' disease is an important cause of heart disfunction in Latin America." | 5.30 | Experimental Chagas' disease: effects of propranolol upon cardiac beta-receptors. ( Enders, J; Fernández, R; Paglini, P; Palma, J; Rivarola, W, 1998) |
| "Chagas' disease is an important cause of heart disfunction in Latin America." | 1.30 | Experimental Chagas' disease: effects of propranolol upon cardiac beta-receptors. ( Enders, J; Fernández, R; Paglini, P; Palma, J; Rivarola, W, 1998) |
| "Patients with Chagas' disease with sole involvement of hollow viscera were also included." | 1.26 | Chagas' heart disease as an experimental model for studies of cardiac autonomic function in man. ( Amorim, DS; Gallo, L; Manço, JC; Marin Neto, JA, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (50.00) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Papadopoulou, MV | 2 |
| Bloomer, WD | 2 |
| Rosenzweig, HS | 2 |
| O'Shea, IP | 2 |
| Wilkinson, SR | 2 |
| Kaiser, M | 2 |
| Chatelain, E | 1 |
| Ioset, JR | 1 |
| Machado, MP | 1 |
| Rocha, AM | 1 |
| de Oliveira, LF | 1 |
| de Cuba, MB | 1 |
| de Oliveira Loss, I | 1 |
| Castellano, LR | 1 |
| Silva, MV | 1 |
| Machado, JR | 1 |
| Nascentes, GA | 1 |
| Paiva, LH | 1 |
| Savino, W | 1 |
| Junior, VR | 1 |
| Brum, PC | 1 |
| Prado, VF | 1 |
| Prado, MA | 1 |
| Silva, EL | 1 |
| Montano, N | 1 |
| Ramirez, LE | 1 |
| Dias da Silva, VJ | 1 |
| Amorim, DS | 3 |
| Manço, JC | 3 |
| Gallo, L | 3 |
| Marin Neto, JA | 1 |
| Sterin-Borda, L | 3 |
| Fink, S | 1 |
| Diez, C | 1 |
| Cossio, P | 1 |
| DeBracco, MD | 1 |
| Caeiro, T | 1 |
| Iosa, D | 1 |
| Tanowitz, HB | 1 |
| Wittner, M | 1 |
| Chen, B | 1 |
| Huang, H | 1 |
| Weiss, LM | 1 |
| Christ, GJ | 1 |
| Braunstein, V | 1 |
| Bilezikian, JP | 1 |
| Morris, SA | 1 |
| Mitelman, J | 1 |
| Gimenez, L | 1 |
| Aparicio, NJ | 1 |
| Fernández, R | 1 |
| Enders, J | 1 |
| Rivarola, W | 1 |
| Palma, J | 1 |
| Paglini, P | 1 |
| Goin, JC | 1 |
| Borda, E | 2 |
| Segovia, A | 1 |
| Pascual, J | 1 |
| Alves, JB | 1 |
| Machado, CR | 1 |
| Zavala Jurado, A | 1 |
| Gonzalez Martin, A | 1 |
| De Feuillade, ND | 1 |
| Liñan, JM | 1 |
| Luquez, HA | 1 |
| Madoery, R | 1 |
| Amuchastegui, SR | 1 |
| Patrignani, JA | 1 |
| Godoy, RA | 2 |
| Tanaka, A | 1 |
2 trials available for propranolol and Chagas Disease
| Article | Year |
|---|---|
Chronic Chagas' disease: possible mechanism of sinus bradycardia.
Topics: Adult; Analysis of Variance; Atropine; Bradycardia; Chagas Disease; Chronic Disease; Cohort Studies; | 1994 |
Long-term effects of a ganglioside mixture on chronic chagasic cardioneuropathy. Preliminary results.
Topics: Adult; Atropine; Blood Pressure; Bradycardia; Chagas Disease; Electrocardiography; Female; Follow-Up | 1998 |
14 other studies available for propranolol and Chagas Disease
| Article | Year |
|---|---|
Discovery of potent nitrotriazole-based antitrypanosomal agents: In vitro and in vivo evaluation.
Topics: Animals; Binding Sites; Cell Line; Chagas Disease; Disease Models, Animal; Leishmania donovani; Mice | 2015 |
3-Nitrotriazole-based piperazides as potent antitrypanosomal agents.
Topics: Animals; Cell Line; Chagas Disease; Dose-Response Relationship, Drug; Humans; Leishmania donovani; M | 2015 |
Autonomic nervous system modulation affects the inflammatory immune response in mice with acute Chagas disease.
Topics: Acute Disease; Animals; Atenolol; Chagas Disease; Electrocardiography; Heart Rate; Inflammation; Mal | 2012 |
Chagas' heart disease as an experimental model for studies of cardiac autonomic function in man.
Topics: Adult; Atropine; Autonomic Nerve Block; Autonomic Nervous System; Blood Pressure; Chagas Cardiomyopa | 1982 |
beta-Adrenergic effect of antibodies from chagasic patients and normal human lymphocytes on isolated rat atria.
Topics: Animals; Antibodies; Chagas Disease; Heart Atria; Heart Rate; Hot Temperature; Humans; Immunoglobuli | 1982 |
Effects of verapamil on acute murine Chagas' disease.
Topics: Acute Disease; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals | 1996 |
Experimental Chagas' disease: effects of propranolol upon cardiac beta-receptors.
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Chagas Disease; Heart Ventricles; Male; Mice; P | 1998 |
Distribution of antibodies against beta-adrenoceptors in the course of human Trypanosoma cruzi infection.
Topics: Acute Disease; Adult; Age Factors; Binding, Competitive; Chagas Disease; Child; Cyclic AMP; Dihydroa | 1991 |
Chagasic IgG modifies the activity of sarcolemmal ATPases through a beta adrenergic mechanism.
Topics: Adrenergic beta-Agonists; Adult; Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Chagas | 1987 |
Effect of adrenoceptor blockers on the acinar enlargement induced by Chagas' disease in the rat submandibular glands.
Topics: Animals; Chagas Disease; Hypertrophy; Phenoxybenzamine; Propranolol; Rats; Submandibular Gland | 1986 |
[Use of propranolol in coronary insufficiency and in some cardiac arrhythmias].
Topics: Adult; Aged; Arrhythmias, Cardiac; Chagas Disease; Coronary Disease; Heart Diseases; Humans; Hyperth | 1968 |
[Symptomatic management of Chagas' heart disease using a beta-adrenergic blocking agent].
Topics: Adult; Cardiomyopathies; Chagas Disease; Electrocardiography; Female; Humans; Male; Middle Aged; Pro | 1968 |
Autonomic blockade in chronic Chagas' heart disease. Heart rate response at rest and during upright exercise. A preliminary report.
Topics: Adult; Atropine; Autonomic Nervous System; Chagas Disease; Female; Heart Diseases; Heart Rate; Human | 1969 |
Hemodynamics in Chagas' disease. A preliminary report.
Topics: Adult; Blood Pressure; Chagas Disease; Dysautonomia, Familial; Exercise Test; Female; Heart Conducti | 1968 |