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propranolol and Central Nervous System Diseases

propranolol has been researched along with Central Nervous System Diseases in 14 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.

Research Excerpts

ExcerptRelevanceReference
" Clinically, propranolol, an agent of this group, has been investigated in the treatment of various clinical disorders including schizophrenia, other psychoses, anxiety disorders, and stress reactions."6.15Propranolol in psychiatry. Therapeutic uses and side effects. ( Ananth, J; Lin, KM, 1986)
"This child developed significant acute dilated cardiomyopathy and severe CNS depression 2 hours after ingesting 3200 mg of propranolol."1.30Acute dilated cardiomyopathy and central nervous system toxicity following propranolol intoxication. ( Lifshitz, M; Zalzstein, E; Zucker, N, 1999)
"In talinolol were in the first place dysrhythmias, hypotension and vomiting and nausea, respectively, in propranolol central-nervous symptoms and hypotension."1.27[Acute beta blocker poisoning]. ( Haustein, KO; Knappe, J; Kulick, B; Oltmanns, G; Schmidt, H; Schwela, H, 1985)
"The hypotension was not affected by pretreatment with propranolol."1.27Insulin-induced hypotension and neurogenic orthostatic hypotension. ( Brown, RT; Deeter, JA; Lee, GK; Polinsky, RJ, 1986)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199010 (71.43)18.7374
1990's3 (21.43)18.2507
2000's0 (0.00)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
El-Shabrawi, M1
Hassanin, F1
Taylor, EA1
Jefferson, D1
Carroll, JD1
Turner, P1
Hale, WE1
Stewart, RB1
Marks, RG1
Lifshitz, M1
Zucker, N1
Zalzstein, E1
Conway, J1
Greenwood, DT1
Middlemiss, DN1
Frishman, W1
Silverman, R1
Strom, J1
Elkayam, U1
Sonnenblick, E1
Dahlöf, C1
Kostis, JB1
Rosen, RC1
Holzer, BC1
Randolph, C1
Taska, LS1
Miller, MH1
Conant, J1
Engler, R1
Janowsky, D1
Maisel, A1
Gilpin, E1
LeWinter, M1
Oltmanns, G1
Schwela, H1
Kulick, B1
Knappe, J1
Haustein, KO1
Schmidt, H1
Ananth, J1
Lin, KM1
Brown, RT1
Polinsky, RJ1
Lee, GK1
Deeter, JA1
Watanabe, T1
Matsuhashi, K1
Takayama, S1
Imura, H1
Nakai, Y1
Matsukura, S1
Matsuyama, H1

Reviews

3 reviews available for propranolol and Central Nervous System Diseases

ArticleYear
Propranolol safety profile in children.
    Current drug safety, 2011, Sep-01, Volume: 6, Issue:4

    Topics: Adrenergic beta-Antagonists; Age Factors; Angina Pectoris; Central Nervous System Diseases; Child; D

2011
Central nervous actions of beta-adrenoreceptor antagonists.
    Clinical science and molecular medicine, 1978, Volume: 54, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Anxiety; Behavior; Central Nervous System; Central Nervous Sys

1978
Propranolol in psychiatry. Therapeutic uses and side effects.
    Neuropsychobiology, 1986, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Anxiety Disorders; Central Nervous System Diseases; Child; Clinical Trials as Top

1986

Trials

3 trials available for propranolol and Central Nervous System Diseases

ArticleYear
CNS side effects of centrally-active antihypertensive agents: a prospective, placebo-controlled study of sleep, mood state, and cognitive and sexual function in hypertensive males.
    Psychopharmacology, 1990, Volume: 102, Issue:2

    Topics: Adult; Affect; Aged; Antihypertensive Agents; Central Nervous System Diseases; Clonidine; Cognition;

1990
Central nervous system side effects of beta-adrenergic blocking agents with high and low lipid solubility.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:4

    Topics: Adult; Affect; Aged; Atenolol; Central Nervous System Diseases; Humans; Lipids; Male; Middle Aged; M

1989
Propranolol in psychiatry. Therapeutic uses and side effects.
    Neuropsychobiology, 1986, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Anxiety Disorders; Central Nervous System Diseases; Child; Clinical Trials as Top

1986

Other Studies

9 other studies available for propranolol and Central Nervous System Diseases

ArticleYear
Cerebrospinal fluid concentrations of propranolol, pindolol and atenolol in man: evidence for central actions of beta-adrenoceptor antagonists.
    British journal of clinical pharmacology, 1981, Volume: 12, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Central Nervous System; Central Nervous System D

1981
Central nervous system symptoms of elderly subjects using antihypertensive drugs.
    Journal of the American Geriatrics Society, 1984, Volume: 32, Issue:1

    Topics: Aged; Antihypertensive Agents; Central Nervous System Diseases; Diuretics; Dizziness; Drug Combinati

1984
Acute dilated cardiomyopathy and central nervous system toxicity following propranolol intoxication.
    Pediatric emergency care, 1999, Volume: 15, Issue:4

    Topics: Acute Disease; Adolescent; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Antidotes; Cardiom

1999
Clinical pharmacology of the new beta-adrenergic blocking drugs. Part 4. Adverse effects. Choosing a beta-adrenoreceptor blocker.
    American heart journal, 1979, Volume: 98, Issue:2

    Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bronchi; Central Nervous System Diseases; Deafnes

1979
Minor Symptoms Evaluation (MSE) Profile--a questionnaire for assessment of subjective CNS-related symptoms.
    Scandinavian journal of primary health care. Supplement, 1990, Volume: 1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzodiazepines; Central Nervous System Diseas

1990
[Acute beta blocker poisoning].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1985, Sep-15, Volume: 40, Issue:18

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Alcohol Drinking; Cardiovascular Diseases; Central N

1985
Insulin-induced hypotension and neurogenic orthostatic hypotension.
    Neurology, 1986, Volume: 36, Issue:10

    Topics: Aged; Blood Glucose; Blood Pressure; Central Nervous System Diseases; Epinephrine; Female; Heart Rat

1986
[Study on the postnatal neuro-behavioral development in rats treated prenatally with drugs acting on the autonomic nervous systems].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:2

    Topics: Animals; Atropine; Autonomic Agents; Central Nervous System Diseases; Chlorpromazine; Epinephrine; F

1985
Effect of intravenous infusion of L-DOPA on plasma growth hormone levels in man.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1973, Volume: 5, Issue:1

    Topics: Adult; Aged; Anorexia Nervosa; Blood Glucose; Central Nervous System Diseases; Dihydroxyphenylalanin

1973