propranolol has been researched along with Cell Transformation, Neoplastic in 7 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Angiosarcomas are rare malignant tumors of vascular origin that represent a genuine therapeutic challenge." | 5.43 | Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study. ( André, N; Banavali, SD; Chougule, A; Ghosh, J; Kavallaris, M; MacKenzie, KL; Meurer, M; Pasquier, E; Philip, DSJ; Rekhi, B; Street, J, 2016) |
| "Treatment of multiple types of oral cancer cells with isoxsuprine led to the downregulation of mesenchymal cell markers that was accompanied by reduced cell motility." | 1.62 | Activation of β2-adrenergic receptor signals suppresses mesenchymal phenotypes of oral squamous cell carcinoma cells. ( Harada, H; Ishigami-Yuasa, M; Kagechika, H; Podyma-Inoue, KA; Sakakitani, S; Takahashi, K; Takayama, R; Watabe, T, 2021) |
| "Angiosarcomas are rare malignant tumors of vascular origin that represent a genuine therapeutic challenge." | 1.43 | Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study. ( André, N; Banavali, SD; Chougule, A; Ghosh, J; Kavallaris, M; MacKenzie, KL; Meurer, M; Pasquier, E; Philip, DSJ; Rekhi, B; Street, J, 2016) |
| " Long exposures (24 h) in dose-response experiments with norepinephrine or epinephrine induced significant increases in DNA damage in treated cells compared to that of untreated controls as measured by the alkaline comet assay." | 1.39 | Chronic exposure to stress hormones promotes transformation and tumorigenicity of 3T3 mouse fibroblasts. ( Baum, A; Chambers, WH; Episcopo, B; Flint, MS; Jenkins, FJ; Knickelbein, KZ; Liegey Dougall, AJ, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Sakakitani, S | 1 |
| Podyma-Inoue, KA | 1 |
| Takayama, R | 1 |
| Takahashi, K | 1 |
| Ishigami-Yuasa, M | 1 |
| Kagechika, H | 1 |
| Harada, H | 1 |
| Watabe, T | 1 |
| Pasquier, E | 1 |
| André, N | 1 |
| Street, J | 1 |
| Chougule, A | 1 |
| Rekhi, B | 1 |
| Ghosh, J | 1 |
| Philip, DSJ | 1 |
| Meurer, M | 1 |
| MacKenzie, KL | 1 |
| Kavallaris, M | 1 |
| Banavali, SD | 1 |
| Flint, MS | 1 |
| Baum, A | 1 |
| Episcopo, B | 1 |
| Knickelbein, KZ | 1 |
| Liegey Dougall, AJ | 1 |
| Chambers, WH | 1 |
| Jenkins, FJ | 1 |
| Brightling, CE | 1 |
| Baker, AJ | 1 |
| Fuller, RW | 1 |
| Gurkalo, VK | 1 |
| Zabezhinskiĭ, MA | 1 |
| Lopez-Barahona, M | 1 |
| Kaplan, PL | 1 |
| Cornet, ME | 1 |
| Diaz-Meco, MT | 1 |
| Larrodera, P | 1 |
| Diaz-Laviada, I | 1 |
| Municio, AM | 1 |
| Moscat, J | 1 |
| Grzanna, R | 1 |
| Frondoza, CG | 1 |
| Hung, GL | 1 |
| Sastre, A | 1 |
7 other studies available for propranolol and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Activation of β2-adrenergic receptor signals suppresses mesenchymal phenotypes of oral squamous cell carcinoma cells.
Topics: Androgen Receptor Antagonists; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; C | 2021 |
Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study.
Topics: Administration, Metronomic; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy | 2016 |
Chronic exposure to stress hormones promotes transformation and tumorigenicity of 3T3 mouse fibroblasts.
Topics: Adrenergic beta-Antagonists; Animals; Carcinogenicity Tests; Cell Transformation, Neoplastic; Comet | 2013 |
Isoprenaline inhibits thromboxane B2 release from U937 cells.
Topics: Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Isoproteren | 1993 |
[Modification of chemical carcinogenesis with adrenergic compounds].
Topics: Adrenergic alpha-Antagonists; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Ant | 1978 |
Kinetic evidence of a rapid activation of phosphatidylcholine hydrolysis by Ki-ras oncogene. Possible involvement in late steps of the mitogenic cascade.
Topics: Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Diglycerides; Enzyme Activation; G | 1990 |
In vivo administration of propranolol delays development of a murine plasmacytoma tumor.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Female; Immunoglobulin G; Mice; Mice, Inbred BA | 1985 |