Page last updated: 2024-11-03

propranolol and Cardiovascular Pregnancy Complications

propranolol has been researched along with Cardiovascular Pregnancy Complications in 72 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"We compared propranolol with methyldopa in a randomized prospective study of 28 women with pregnancy associated hypertension."9.05Propranolol in pregnancy three year prospective study. ( Bevan, EB; Craswell, PW; Eadie, MJ; Livingstone, I; Smith, MT, 1983)
"The treatment of the mentioned forms of hypertension with propranolol during pregnancy either as monotherapy or in combination with dihydralazine and after careful exclusion of the contraindications described represents a further effective therapy."7.67[Experiences with propranolol (Obsidan25) in hypertension therapy in pregnancy]. ( Glöckner, R; Peiker, G; Siegert, C; Traeger, A; Völkner, E, 1985)
"A hypertensive women was treated throughout pregnancy with propranolol 40 mg daily without complication."7.66Anti-hypertensive therapy with propranolol during pregnancy and lactation. ( Taylor, EA; Turner, P, 1981)
"A combination of propranolol and hydrallazine was administered to 13 patients with longstanding hypertension during 15 pregnancies."7.66Propranolol and hydrallazine in the management of essential hypertension in pregnancy. ( Bott-Kanner, G; Joel-Cohen, SJ; Reisner, SH; Rosenfeld, JB; Schweitzer, A, 1980)
"A case is presented of a low birth weight infant born prematurely with depressed respiration, sinus bradycardia, and hypoglycemia associated with maternal propranolol therapy during pregnancy and up until labor and delivery."7.66Propranolol therapy during pregnancy in a patient with idiopathic hypertrophic subaortic stenosis: is it safe? ( Curry, RC; Sabom, MB; Wise, DE, 1978)
"Twenty-five women were treated with propranolol during 26 pregnancies complicated by hypertension."7.66Propranolol for the treatment of hypertension in pregnancy. ( Eliahou, HE; Mashiach, S; Reisin, E; Romem, I; Serr, DM; Silverberg, DS, 1978)
"A retrospective study is presented of the effect of propranolol on fetal outcome in pregnancies complicated by maternal hypertension."7.66The possible adverse effect of propranolol on the fetus in pregnancies complicated by severe hypertension. ( Beard, RW; Belsey, E; Cohen, SL; Lieberman, BA; Pinker, GD; Stirrat, GM, 1978)
"Ten hypertensive patients were treated with propranolol throughout pregnancy."7.65[Treatment of arterial hypertension with propranolol in pregnant women. 10 cases]. ( Kreft, C; Tcherdakoff, Ph, 1977)
"The administration of 160 mg of propranolol during pregnancy, labor, and delivery was associated with profound hypoglycemia and respiratory depression in a newborn infant."7.65Propranolol therapy during pregnancy, labor, and delivery: evidence for transplacental drug transfer and impaired neonatal drug disposition. ( Cottrill, CM; Gettes, L; McAllister, RG; Noonan, JA, 1977)
"Treatment with propranolol and hydralazine was effective in controlling her blood pressure and was continued throughout her next two pregnancies, both of which were successful."5.26Treatment with propranolol and hydralazine throughout pregnancy in a hypertensive patient. A case report. ( Bott-Kanner, G; Joel-Cohen, J; Rosenfeld, JB; Schoenfeld, A; Schweitzer, A, 1978)
"Fifty-one women with pregnancy-induced hypertension (PIH) were randomly allocated to one of three treatment groups: A: hydralazine (13); B: hydralazine and propranolol (17); and C: hydralazine and pindolol (19)."5.08Beta-adrenergic blocking agents in the treatment of pregnancy-induced hypertension. ( Holzberg, G; Insler, V; Mazor, M; Paran, E; Zmora, E, 1995)
"We compared propranolol with methyldopa in a randomized prospective study of 28 women with pregnancy associated hypertension."5.05Propranolol in pregnancy three year prospective study. ( Bevan, EB; Craswell, PW; Eadie, MJ; Livingstone, I; Smith, MT, 1983)
"The treatment of the mentioned forms of hypertension with propranolol during pregnancy either as monotherapy or in combination with dihydralazine and after careful exclusion of the contraindications described represents a further effective therapy."3.67[Experiences with propranolol (Obsidan25) in hypertension therapy in pregnancy]. ( Glöckner, R; Peiker, G; Siegert, C; Traeger, A; Völkner, E, 1985)
"A hypertensive women was treated throughout pregnancy with propranolol 40 mg daily without complication."3.66Anti-hypertensive therapy with propranolol during pregnancy and lactation. ( Taylor, EA; Turner, P, 1981)
"A combination of propranolol and hydrallazine was administered to 13 patients with longstanding hypertension during 15 pregnancies."3.66Propranolol and hydrallazine in the management of essential hypertension in pregnancy. ( Bott-Kanner, G; Joel-Cohen, SJ; Reisner, SH; Rosenfeld, JB; Schweitzer, A, 1980)
"A case is presented of a low birth weight infant born prematurely with depressed respiration, sinus bradycardia, and hypoglycemia associated with maternal propranolol therapy during pregnancy and up until labor and delivery."3.66Propranolol therapy during pregnancy in a patient with idiopathic hypertrophic subaortic stenosis: is it safe? ( Curry, RC; Sabom, MB; Wise, DE, 1978)
"Twenty-five women were treated with propranolol during 26 pregnancies complicated by hypertension."3.66Propranolol for the treatment of hypertension in pregnancy. ( Eliahou, HE; Mashiach, S; Reisin, E; Romem, I; Serr, DM; Silverberg, DS, 1978)
"A retrospective study is presented of the effect of propranolol on fetal outcome in pregnancies complicated by maternal hypertension."3.66The possible adverse effect of propranolol on the fetus in pregnancies complicated by severe hypertension. ( Beard, RW; Belsey, E; Cohen, SL; Lieberman, BA; Pinker, GD; Stirrat, GM, 1978)
"Ten hypertensive patients were treated with propranolol throughout pregnancy."3.65[Treatment of arterial hypertension with propranolol in pregnant women. 10 cases]. ( Kreft, C; Tcherdakoff, Ph, 1977)
"The administration of 160 mg of propranolol during pregnancy, labor, and delivery was associated with profound hypoglycemia and respiratory depression in a newborn infant."3.65Propranolol therapy during pregnancy, labor, and delivery: evidence for transplacental drug transfer and impaired neonatal drug disposition. ( Cottrill, CM; Gettes, L; McAllister, RG; Noonan, JA, 1977)
"Pregnancy in the Marfan syndrome is associated with two primary problems: potential catastrophic aortic dissection and the risk for having a child with the syndrome."2.39Cardiovascular problems in pregnant women with the Marfan syndrome. ( Elkayam, U; Mehra, A; Ostrzega, E; Shotan, A, 1995)
"During evaluation for palpitations, presyncope, or syncope, seven pregnant women had documented ventricular tachycardia."2.38New-onset ventricular tachycardia during pregnancy. ( Allen, B; Brodsky, M; Doria, R; Sada, M; Sato, D; Thomas, G, 1992)
"The use of beta blockers during treatment of mitral stenosis is discussed on four cases involving females patients who are symptomatic."1.30[Role of beta-blockers in the treatment of mitral stenosis, apropos of 4 cases]. ( Ba, SA; Diop, IB; Diouf, SM; Fall, MD; Hane, L; Kane, A; Sarr, M, 1997)
"Supraventricular tachycardia is relatively common in pregnancy, and is related to the normal physiologic changes of the cardiovascular system in the gravid state."1.28Supraventricular tachycardia resistant to treatment in a pregnant woman. ( Hulkower, S; Kostic, B; Treakle, K, 1992)
"Renal hypertension was induced by clamping both renal arteries 4 weeks before pregnancy."1.27The acute effects of a non-selective beta-adrenergic blocking agent in hypertensive pregnant rats. ( Karlsson, K; Ljungblad, U; Lundgren, Y, 1984)
"Propranolol is a beta-adrenergic blocking drug with a wide spectrum of use and may diverse pharmacologic effects."1.26Propranolol and parturition. ( Datta, S; Kitzmiller, JL; Ostheimer, GW; Schoenbaum, SC, 1978)
"Treatment with propranolol and hydralazine was effective in controlling her blood pressure and was continued throughout her next two pregnancies, both of which were successful."1.26Treatment with propranolol and hydralazine throughout pregnancy in a hypertensive patient. A case report. ( Bott-Kanner, G; Joel-Cohen, J; Rosenfeld, JB; Schoenfeld, A; Schweitzer, A, 1978)

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-199061 (84.72)18.7374
1990's8 (11.11)18.2507
2000's1 (1.39)29.6817
2010's2 (2.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duan, L1
Ng, A1
Chen, W1
Spencer, HT1
Nguyen, J1
Shen, AY1
Lee, MS1
Habashi, JP1
MacFarlane, EG1
Bagirzadeh, R1
Bowen, C1
Huso, N1
Chen, Y1
Bedja, D1
Creamer, TJ1
Rykiel, G1
Manning, M1
Huso, D1
Dietz, HC1
Tang, RA1
Dorotheo, EU1
Schiffman, JS1
Bahrani, HM1
Moses, JW1
Borer, JS1
Karlsson, K1
Lundgren, Y1
Ljungblad, U1
Halawa, B1
Mazurek, W1
Margulis, E1
Binder, D1
Cohen, AW1
Bruner, JP1
Barry, MJ1
Elliott, JP1
Livingstone, I1
Craswell, PW1
Bevan, EB1
Smith, MT1
Eadie, MJ1
Berkowitz, RL1
Ueland, K1
McAnulty, JH1
Ueland, FR1
Metcalfe, J1
Alpert, BS1
Boineau, J1
Strong, WB1
Boice, JL1
Silas, JH1
Woods, HF1
Singer, A1
Brown, VA1
Taylor, EA1
Turner, P1
Bott-Kanner, G2
Schweitzer, A2
Reisner, SH1
Joel-Cohen, SJ1
Rosenfeld, JB2
Paran, E1
Holzberg, G1
Mazor, M1
Zmora, E1
Insler, V1
Elkayam, U1
Ostrzega, E1
Shotan, A1
Mehra, A1
Cheng, TO1
Kam, RM1
Lee, CY1
Teo, WS1
McCurdy, CM1
Rutherford, SE1
Coddington, CC1
Kane, A1
Ba, SA1
Fall, MD1
Sarr, M1
Diop, IB1
Hane, L1
Diouf, SM1
Tcherdakoff, P3
Dubois, D1
Petitcolas, J1
Monnier, JC1
Honore, P1
Lanciaux, B1
Boulogne, M1
Greer, M1
Serup, J2
Sachs, BP1
Van Iddekinge, B1
Tcherdakoff, Ph2
Kreft, C3
Sabom, MB1
Curry, RC1
Wise, DE1
Datta, S1
Kitzmiller, JL1
Ostheimer, GW2
Schoenbaum, SC1
Oakley, GD1
McGarry, K1
Limb, DG1
Oakley, CM3
Pruyn, SC1
Phelan, JP1
Buchanan, GC1
Eliahou, HE1
Silverberg, DS1
Reisin, E1
Romem, I1
Mashiach, S1
Serr, DM1
Schoenfeld, A1
Joel-Cohen, J1
Lieberman, BA1
Stirrat, GM1
Cohen, SL1
Beard, RW1
Pinker, GD1
Belsey, E1
Colliard, M1
Berrard, E1
Dupay, A1
Bernaille, JM1
Cottrill, CM1
McAllister, RG1
Gettes, L1
Noonan, JA1
Alper, MH1
Kolibash, AJ1
Ruiz, DE1
Lewis, RP1
Woods, JR1
Brinkman, CR1
Tymieniecka-Iwanik, J1
Wszelaki-Lass, E1
Treakle, K1
Kostic, B1
Hulkower, S1
Brodsky, M1
Doria, R1
Allen, B1
Sato, D1
Thomas, G1
Sada, M1
Fogari, R1
Zoppi, A1
Kawecka-Jaszcz, K1
Skoczeń, M1
Norès, JM1
Lignières, G1
Hoffmann-Traeger, A1
Peiker, G2
Glöckner, R2
Wittmann, I1
Balogh, A1
Henschel, L1
Rubin, PC1
Butters, L1
McCabe, R1
Kelman, A1
Cola, LM1
Lavin, JP1
Bergmans, MG1
Jonker, GJ1
Kock, HC1
Schalm, SW1
van Buuren, HR1
Redgrave, JE1
Swartz, SL1
Campbell, JW1
Siegert, C1
Völkner, E1
Traeger, A1
Requena Laviña, M1
Cosío, FG1
Fernández-Yáñez, J1
García Alarilla, M1
Bajo Arenas, J1
Fiddler, GI1
Goodwin, JF2
Perrotin, M1
Pauly-Laubry, C1
Forman, J1
Maurice, P1
Turner, GM1
Dixon, HG1
Fernandes, M1
Kim, KE1
Moyer, JH1
Levitan, AA1
Manion, JC1
Maljar, L1
Sakson, N1
Szwarc, B1
Morín, T1
Aitken, RR1
Drake, CG1
Batts, JA1
Tchilinguirian, NG1
Passmore, J1
Schroeder, JS1
Harrison, DC1
Ledwich, JR1
Fay, JE1
Seaton, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Propranolol Versus Placebo for Induction of Labor in Nulliparous Patients: a Double-blind Randomized Controlled Trial[NCT03348683]Phase 2240 participants (Actual)Interventional2017-12-11Completed
Propranolol for Prolonged Labor: A Randomized Controlled Trial (PRO-Labor Trial)[NCT04741698]Phase 180 participants (Actual)Interventional2021-07-27Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration of Latent

Time of latent labor defined as <6cm of cervical dilation. (NCT03348683)
Timeframe: average of 24 hours

Interventionhours (Mean)
Propranolol11.0
Placebo11.2

Number of Fetus With Fetal Bradycardia

Count of fetus with fetal bradycardia (<110bpm for >10 minutes within 30 minutes of study drug administration) (NCT03348683)
Timeframe: 30 minutes from drug administration

InterventionParticipants (Count of Participants)
Propranolol1
Placebo0

Number of Fetus With Heart Rate Decelerations

Count of fetus with fetal heart rate decelerations within 30 minutes of study drug administration (NCT03348683)
Timeframe: 30 minutes from drug administration

InterventionParticipants (Count of Participants)
Propranolol15
Placebo13

Number of Neonates With Hypoglycemia

"Neonatal outcome - Number of neonates with hypoglycemia (blood glucose <50).~This population includes only the neonates who had heelsticks to check their blood glucose, which is not a universal practice and was not required by the protocol or IRB. The neonates included were those who met the nursery's risk-based protocol to check blood glucose after birth (ex: infants of diabetic mothers, fetal growth restriction, macrosomia, or symptoms suggestive of hypoglycemia)" (NCT03348683)
Timeframe: Day 1

InterventionParticipants (Count of Participants)
Propranolol11
Placebo8

Number of Neonates With Neonatal Outcome Composite Score = 1

"Composite neonatal outcome score was for any of the following morbidity: Neonatal Intensive Care Unit (NICU) admission, respiratory support (CPAP, nasal cannula, intubation), culture proven sepsis, radiographically proven intracranial hemorrhage, necrotizing enterocolitis, hypoglycemia (for those infants who had sugar checked), and neonatal death.~The composite score was computed as a score of 1 for any indication of neonatal morbidity - neonates who experienced at least one morbidity and the components are given equal weights. Patients who had no evidence of the predefined neonatal morbidities are subsequently given a score of 0. The minimum is 0 and maximum is 1." (NCT03348683)
Timeframe: Day 1

InterventionParticipants (Count of Participants)
Propranolol21
Placebo28

Number of Participants With Maternal Morbidity Composite Score = 1

"Composite maternal morbidity score consists of a count of postpartum hemorrhage, transfusion, hysterectomy, placental abruption, chorioamnionitis, shoulder dystocia, episiotomy, higher order laceration, and ICU admission.~The composite score was computed as a score of 1 for any indication of maternal morbidity, that is the participant experienced at least one maternal morbidity, and the components are given equal weights. Participants who had no evidence of the predefined maternal morbidities are subsequently given a score of 0. The minimum is 0 and maximum is 1." (NCT03348683)
Timeframe: average of 24 hours

InterventionParticipants (Count of Participants)
Propranolol35
Placebo49

Number of Participants With Postpartum Hemorrhage

Greater than 500cc of blood expelled during a vaginal delivery or greater than 1000cc of blood expelled during a cesarean section (NCT03348683)
Timeframe: 30 minutes from drug administration

InterventionParticipants (Count of Participants)
Propranolol15
Placebo26

Time From Beginning of Induction to Delivery

The time of induction (based on time of foley balloon placement for cervical ripening or misoprostol administration) to the time of delivery of the infant. (NCT03348683)
Timeframe: average of 24 hours

Interventionhours (Mean)
Propranolol13.8
Placebo14.3

Number of Participants With Various Mode of Delivery

Number of various mode of delivery - count of Vaginal delivery, vacuum assisted vaginal delivery, forceps assisted vaginal delivery, cesarean section (NCT03348683)
Timeframe: average of 24 hours

,
InterventionParticipants (Count of Participants)
Spontaneous vaginal deliveryVacuum assisted vaginal deliveryForceps assisted vaginal deliveryCesarean section
Placebo6110840
Propranolol643846

Reviews

12 reviews available for propranolol and Cardiovascular Pregnancy Complications

ArticleYear
Beta-adrenergic antagonists in the treatment of patients with heart disease.
    Disease-a-month : DM, 1981, Volume: 27, Issue:9

    Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca

1981
[Cardiomyopathies and their treatment].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1980, May-01, Volume: 33, Issue:9

    Topics: Adult; Aged; Aortic Stenosis, Subvalvular; Cardiomegaly; Cardiomyopathies; Cardiomyopathy, Alcoholic

1980
Anti-hypertensive drugs in the pregnant patient.
    Obstetrical & gynecological survey, 1980, Volume: 35, Issue:4

    Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide

1980
Special considerations in the use of cardiovascular drugs.
    Clinical obstetrics and gynecology, 1981, Volume: 24, Issue:3

    Topics: Anti-Arrhythmia Agents; Anticoagulants; Cardiac Glycosides; Cardiovascular Agents; Disopyramide; Diu

1981
Cardiovascular problems in pregnant women with the Marfan syndrome.
    Annals of internal medicine, 1995, Jul-15, Volume: 123, Issue:2

    Topics: Delivery, Obstetric; Female; Genetic Counseling; Humans; Labor, Obstetric; Marfan Syndrome; Pregnanc

1995
[Propranolol in treatment of hypertension in pregnancy].
    Ugeskrift for laeger, 1979, Dec-03, Volume: 141, Issue:49

    Topics: Female; Hemodynamics; Humans; Hypertension; Infant, Newborn; Pregnancy; Pregnancy Complications; Pre

1979
New-onset ventricular tachycardia during pregnancy.
    American heart journal, 1992, Volume: 123, Issue:4 Pt 1

    Topics: Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Exercise Test; Female; Follo

1992
[Beta-blockers in the therapy of arterial hypertension in pregnancy].
    Minerva ginecologica, 1985, Volume: 37, Issue:5

    Topics: Adrenergic beta-Antagonists; Diuretics; Female; Humans; Hypertension; Methyldopa; Oxprenolol; Pre-Ec

1985
[Beta-blockaders in the treatment of hypertension in pregnancy].
    Kardiologia polska, 1985, Volume: 28, Issue:5

    Topics: Adrenergic beta-Antagonists; Atenolol; Drug Evaluation; Female; Humans; Hypertension; Metoprolol; Ox

1985
Fetal supraventricular tachycardia. Review of the literature.
    Obstetrical & gynecological survey, 1985, Volume: 40, Issue:2

    Topics: Adult; Cesarean Section; Digitalis; Drug Therapy, Combination; Electric Countershock; Electrocardiog

1985
The cardiomyopathies.
    British heart journal, 1972, Volume: 34, Issue:6

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Anticoagulants; Atrial Fibrillation; Cardiomegaly; Car

1972
Hypertensive emergencies.
    Pennsylvania medicine, 1974, Volume: 77, Issue:7

    Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Antihypertensive Agents; Aortic Aneurysm; Blood Volume

1974

Trials

3 trials available for propranolol and Cardiovascular Pregnancy Complications

ArticleYear
Propranolol in pregnancy three year prospective study.
    Clinical and experimental hypertension. Part B, Hypertension in pregnancy, 1983, Volume: 2, Issue:2

    Topics: Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Kinetics; Lactates;

1983
Beta-adrenergic blocking agents in the treatment of pregnancy-induced hypertension.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Blood Pressure; Drug Therapy, Combination; Female

1995
Prevention of recurrent variceal bleeding: non-surgical procedures.
    Clinics in gastroenterology, 1985, Volume: 14, Issue:1

    Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Humans; Liver Circulation; Liver C

1985

Other Studies

57 other studies available for propranolol and Cardiovascular Pregnancy Complications

ArticleYear
β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies.
    JAMA internal medicine, 2017, 06-01, Volume: 177, Issue:6

    Topics: Adrenergic beta-Antagonists; Age Factors; Arrhythmias, Cardiac; Atenolol; Body Mass Index; Californi

2017
Oxytocin antagonism prevents pregnancy-associated aortic dissection in a mouse model of Marfan syndrome.
    Science translational medicine, 2019, 05-01, Volume: 11, Issue:490

    Topics: Adrenergic beta-Antagonists; Animals; Aorta; Aortic Dissection; Disease Models, Animal; Female; Hydr

2019
Medical and surgical management of idiopathic intracranial hypertension in pregnancy.
    Current neurology and neuroscience reports, 2004, Volume: 4, Issue:5

    Topics: Adolescent; Adult; Anticonvulsants; Antihypertensive Agents; Diagnosis, Differential; Diuretics; Fem

2004
Beta-blockers in pregnancy.
    The New England journal of medicine, 1982, Apr-01, Volume: 306, Issue:13

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Female; Fetus; Humans; Hypertension; In

1982
The acute effects of a non-selective beta-adrenergic blocking agent in hypertensive pregnant rats.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 118

    Topics: Adrenergic beta-Antagonists; Animals; Cardiac Output; Female; Heart Rate; Hemodynamics; Hypertension

1984
The effect of propranolol on the nonstress test.
    American journal of obstetrics and gynecology, 1984, Feb-01, Volume: 148, Issue:3

    Topics: Adolescent; Adult; Female; Fetal Monitoring; Fetus; Humans; Hypertension; Pregnancy; Pregnancy Compl

1984
Pregnancy in a patient with idiopathic long QT syndrome.
    American journal of obstetrics and gynecology, 1984, Jul-15, Volume: 149, Issue:6

    Topics: Adult; Arrhythmias, Cardiac; Autonomic Nerve Block; Electrocardiography; Female; Heart; Humans; Preg

1984
Exercise-induced ventricular tachycardia.
    Pediatric cardiology, 1982, Volume: 2, Issue:1

    Topics: Adolescent; Child; Electrocardiography; Exercise Test; Female; Heart Rate; Heart Ventricles; Humans;

1982
Propranolol during pregnancy.
    JAMA, 1982, Oct-15, Volume: 248, Issue:15

    Topics: Female; Fetus; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications, Cardiovascular;

1982
Successful pregnancy soon after oral contraceptive-associated malignant hypertension.
    Postgraduate medical journal, 1980, Volume: 56, Issue:661

    Topics: Adult; Contraceptives, Oral; Female; Humans; Hypertension, Malignant; Pregnancy; Pregnancy Complicat

1980
Anti-hypertensive therapy with propranolol during pregnancy and lactation.
    Postgraduate medical journal, 1981, Volume: 57, Issue:669

    Topics: Breast Feeding; Female; Humans; Hypertension; Infant, Newborn; Lactation; Milk, Human; Pregnancy; Pr

1981
Propranolol and hydrallazine in the management of essential hypertension in pregnancy.
    British journal of obstetrics and gynaecology, 1980, Volume: 87, Issue:2

    Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Hypoglycemia; Infant, N

1980
Caution in use of beta blockers during pregnancy.
    Catheterization and cardiovascular diagnosis, 1995, Volume: 34, Issue:2

    Topics: Adrenergic beta-Antagonists; Catheterization; Female; Heart Rate; Humans; Infant, Newborn; Maternal-

1995
A pregnant lady with narrow complex tachycardia.
    Singapore medical journal, 1994, Volume: 35, Issue:1

    Topics: Adult; Diagnosis, Differential; Digoxin; Drug Therapy, Combination; Electrocardiography; Female; Hum

1994
Syncope and sudden arrhythmic death complicating pregnancy. A case report of Romano-Ward syndrome.
    The Journal of reproductive medicine, 1993, Volume: 38, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Bradycardia; Cesarean Section; Death, Sudden, Cardiac; Electric

1993
[Role of beta-blockers in the treatment of mitral stenosis, apropos of 4 cases].
    Dakar medical, 1997, Volume: 42, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Anemia; Anti-Arrhythmia Agents; Digitalis Glycosides; Diuretics;

1997
[Beta-blockers and arterial hypertension in the pregnant woman].
    La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31

    Topics: Adrenergic beta-Antagonists; Female; Fetal Heart; Humans; Hypertension; Maternal-Fetal Exchange; Pre

1978
[beta-blockers and high risk pregnancies. Viewpoint of the nephrologist and the obstetrician].
    La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31

    Topics: Acebutolol; Adrenergic beta-Antagonists; Female; Humans; Hypertension; Pindolol; Pregnancy; Pregnanc

1978
[Value of hydralazine-beta blockader association in hypertension of pregnancy].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1978, Volume: 23, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Drug Therapy, Combination; Female; Fetus; Humans; Hydralazine; H

1978
Pre-term baby: an inheritance of a different kind.
    Nursing mirror, 1979, Dec-06, Volume: 149, Issue:23

    Topics: Adult; Female; Humans; Hypertension; Infant, Newborn; Infant, Premature, Diseases; Male; Pregnancy;

1979
Successful pregnancy in a patient with autosomal dominant ventricular dysrhythmia.
    American journal of obstetrics and gynecology, 1979, Apr-15, Volume: 133, Issue:8

    Topics: Adult; Arrhythmias, Cardiac; Chromosome Aberrations; Chromosome Disorders; Female; Fetal Death; Gene

1979
Propranolol for the treatment of hypertension in pregnancy.
    Acta medica Scandinavica, 1979, Volume: 206, Issue:4

    Topics: Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Propranolol

1979
[Treatment of arterial hypertension with propranolol in pregnant women. 10 cases].
    La Nouvelle presse medicale, 1977, Feb-26, Volume: 6, Issue:8

    Topics: Adult; Birth Weight; Blood Pressure; Cesarean Section; Delivery, Obstetric; Female; Humans; Hyperten

1977
Propranolol therapy during pregnancy in a patient with idiopathic hypertrophic subaortic stenosis: is it safe?
    Southern medical journal, 1978, Volume: 71, Issue:3

    Topics: Adult; Aortic Stenosis, Subvalvular; Cardiomyopathy, Hypertrophic; Female; Fetus; Heart Rate; Humans

1978
Propranolol and parturition.
    Obstetrics and gynecology, 1978, Volume: 51, Issue:5

    Topics: Adult; Anesthesia, Local; Anesthesia, Obstetrical; Aortic Stenosis, Subvalvular; Cardiomyopathy, Hyp

1978
Management of pregnancy in patients with hypertrophic cardiomyopathy.
    British medical journal, 1979, Jun-30, Volume: 1, Issue:6180

    Topics: Adult; Cardiomyopathy, Hypertrophic; Delivery, Obstetric; Depression, Chemical; Female; Fetal Heart;

1979
Long-term propranolol therapy in pregnancy: maternal and fetal outcome.
    American journal of obstetrics and gynecology, 1979, Oct-15, Volume: 135, Issue:4

    Topics: Asphyxia Neonatorum; Bradycardia; Female; Fetal Growth Retardation; Fetus; Humans; Hypertension; Hyp

1979
Long-term propranolol therapy in pregnancy: maternal and fetal outcome.
    American journal of obstetrics and gynecology, 1979, Oct-15, Volume: 135, Issue:4

    Topics: Asphyxia Neonatorum; Bradycardia; Female; Fetal Growth Retardation; Fetus; Humans; Hypertension; Hyp

1979
Long-term propranolol therapy in pregnancy: maternal and fetal outcome.
    American journal of obstetrics and gynecology, 1979, Oct-15, Volume: 135, Issue:4

    Topics: Asphyxia Neonatorum; Bradycardia; Female; Fetal Growth Retardation; Fetus; Humans; Hypertension; Hyp

1979
Long-term propranolol therapy in pregnancy: maternal and fetal outcome.
    American journal of obstetrics and gynecology, 1979, Oct-15, Volume: 135, Issue:4

    Topics: Asphyxia Neonatorum; Bradycardia; Female; Fetal Growth Retardation; Fetus; Humans; Hypertension; Hyp

1979
Propranolol for the treatment of hypertension in pregnancy.
    British journal of obstetrics and gynaecology, 1978, Volume: 85, Issue:6

    Topics: Adult; Apgar Score; Chlorthalidone; Female; Fetal Death; Humans; Hypertension; Infant, Newborn; Infa

1978
Treatment with propranolol and hydralazine throughout pregnancy in a hypertensive patient. A case report.
    Israel journal of medical sciences, 1978, Volume: 14, Issue:4

    Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Pregnancy; Pregnancy Co

1978
The possible adverse effect of propranolol on the fetus in pregnancies complicated by severe hypertension.
    British journal of obstetrics and gynaecology, 1978, Volume: 85, Issue:9

    Topics: Birth Weight; Female; Fetal Death; Humans; Hypertension; Infant, Newborn; Pregnancy; Pregnancy Compl

1978
Propranolol in hypertension during pregnancy.
    British medical journal, 1978, Sep-02, Volume: 2, Issue:6138

    Topics: Adult; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Propranolol

1978
Propranolol therapy during pregnancy, labor, and delivery: evidence for transplacental drug transfer and impaired neonatal drug disposition.
    The Journal of pediatrics, 1977, Volume: 91, Issue:5

    Topics: Adult; Apnea; Female; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Male; Matern

1977
[Use of beta blockers (propranolol) in the treatment of arterial hypertension during pregnancy].
    Acquisitions medicales recentes, 1977

    Topics: Drug Evaluation; Female; Fetus; Humans; Hypertension; Infant, Newborn; Pregnancy; Pregnancy Complica

1977
Intrapartum anesthetic management of the pregnant patient with heart disease.
    Clinical obstetrics and gynecology, 1975, Volume: 18, Issue:3

    Topics: Anesthesia, Epidural; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Local; Anesthesia, Ob

1975
Idiopathic hypertrophic subaortic stenosis in pregnancy.
    Annals of internal medicine, 1975, Volume: 82, Issue:6

    Topics: Adult; Aortic Stenosis, Subvalvular; Cardiac Catheterization; Cardiomyopathy, Hypertrophic; Cineangi

1975
The treatment of gestational hypertension.
    The Journal of reproductive medicine, 1975, Volume: 15, Issue:5

    Topics: Antihypertensive Agents; Chronic Disease; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hype

1975
[Evaluation of the action of Polfa propranolol administered to women with various pathological conditions].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1976, Apr-15, Volume: 29, Issue:8

    Topics: Female; Humans; Hyperthyroidism; Pregnancy; Pregnancy Complications; Pregnancy Complications, Cardio

1976
Supraventricular tachycardia resistant to treatment in a pregnant woman.
    The Journal of family practice, 1992, Volume: 35, Issue:5

    Topics: Adult; Anti-Arrhythmia Agents; Drug Therapy, Combination; Electric Countershock; Female; Flecainide;

1992
[Hypertension in pregnant women and beta-blockers. Follow-up of 31 pregnancies].
    Revue francaise de gynecologie et d'obstetrique, 1988, Volume: 83, Issue:10

    Topics: Adult; Blood Pressure; Embryonic and Fetal Development; Female; Follow-Up Studies; Humans; Hypertens

1988
The influence of phenobarbital on the pharmacokinetics of propranolol in pregnancy.
    Biological research in pregnancy and perinatology, 1987, Volume: 8, Issue:2 2D Half

    Topics: Drug Interactions; Female; Half-Life; Humans; Hypertension; Phenobarbital; Pregnancy; Pregnancy Comp

1987
The influence of pregnancy on drug action: concentration-effect modelling with propranolol.
    Clinical science (London, England : 1979), 1987, Volume: 73, Issue:1

    Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Kinetics; Pregnancy; Pregnancy Comp

1987
Pregnancy complicated by Marfan's syndrome with aortic arch dissection, subsequent aortic arch replacement and triple coronary artery bypass grafts.
    The Journal of reproductive medicine, 1985, Volume: 30, Issue:9

    Topics: Adult; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Cesarean Section; Coronary Artery Bypass

1985
Diagnosis and management of malignant hypertension.
    Comprehensive therapy, 1985, Volume: 11, Issue:3

    Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Malignant; Kidney Function Tests

1985
A possible teratogenic effect of propranolol.
    The New England journal of medicine, 1985, Aug-22, Volume: 313, Issue:8

    Topics: Abnormalities, Drug-Induced; Adult; Female; Humans; Hypertension; Infant, Newborn; Pregnancy; Pregna

1985
[Experiences with propranolol (Obsidan25) in hypertension therapy in pregnancy].
    Die Pharmazie, 1985, Volume: 40, Issue:9

    Topics: Blood Pressure; Dihydralazine; Female; Heart Rate; Humans; Hypertension; Infant, Newborn; Kinetics;

1985
[Treatment of mitral stenosis with propranolol in pregnancy and the puerperium].
    Medicina clinica, 1985, Oct-05, Volume: 85, Issue:10

    Topics: Adult; Diuretics; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Mitral Valve Stenosis;

1985
Letter: Propranolol and pregnancy.
    Lancet (London, England), 1974, Sep-21, Volume: 2, Issue:7882

    Topics: Adult; Birth Weight; Cardiomegaly; Female; Fetus; Humans; Hypoglycemia; Infant, Newborn; Infant, New

1974
Congestive and hypertrophic cardiomyopathies. A decade of study.
    Lancet (London, England), 1970, Apr-11, Volume: 1, Issue:7650

    Topics: Blood Pressure; Cardiomegaly; Coronary Disease; Death, Sudden; Dilatation; Female; Heart Diseases; H

1970
[Obstructive cardiomyopathy and atrio-ventricular conduction disorder].
    Archives des maladies du coeur et des vaisseaux, 1973, Volume: 66, Issue:6

    Topics: Adult; Cardiac Catheterization; Cardiomyopathy, Hypertrophic; Electrocardiography; Electrodes, Impla

1973
Management of pregnancy complicated by hypertrophic obstructive cardiomyopathy.
    British medical journal, 1968, Nov-02, Volume: 4, Issue:5626

    Topics: Adolescent; Adult; Blood Transfusion; Cardiomegaly; Cardiomyopathy, Hypertrophic; Cesarean Section;

1968
Propranolol therapy during pregnancy and lactation.
    The American journal of cardiology, 1973, Volume: 32, Issue:2

    Topics: Female; Humans; Lactation; Milk, Human; Pregnancy; Pregnancy Complications, Cardiovascular; Proprano

1973
[Thyrotoxic cardiopathy in pregnancy].
    Revista clinica espanola, 1973, Jun-15, Volume: 129, Issue:5

    Topics: Administration, Oral; Adult; Female; Humans; Hyperthyroidism; Injections, Intravenous; Potassium Iod

1973
A technique of anesthesia with induced hypotension for surgical correction of intracranial aneurysms.
    Clinical neurosurgery, 1974, Volume: 21

    Topics: Anesthesia, General; Blood Pressure Determination; Female; Halothane; Humans; Hypotension, Controlle

1974
Pheochromocytoma in pregnancy: a case report and review of the pathophysiology.
    American journal of obstetrics and gynecology, 1974, Feb-15, Volume: 118, Issue:4

    Topics: Adrenal Gland Neoplasms; Adult; Catecholamines; Cesarean Section; Epinephrine; Female; Heart Arrest;

1974
Repeated cardioversion during pregnancy. Treatment of refractory paroxysmal atrial tachycardia during 3 successive pregnancies.
    The American journal of cardiology, 1971, Volume: 27, Issue:4

    Topics: Adult; Electric Countershock; Electrocardiography; Female; Humans; Pregnancy; Pregnancy Complication

1971
Idiopathic recurrent ventricular fibrillation.
    The American journal of cardiology, 1969, Volume: 24, Issue:2

    Topics: Adult; Electrocardiography; Female; Humans; Injections, Intravenous; Pregnancy; Pregnancy Complicati

1969
Quinidine-induced paroxysmal ventricular fibrillation treated with propranolol.
    British medical journal, 1966, Jun-18, Volume: 1, Issue:5502

    Topics: Adult; Atrial Fibrillation; Female; Humans; Mitral Valve Stenosis; Pregnancy; Pregnancy Complication

1966