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propranolol and Cardiomyopathy, Congestive

propranolol has been researched along with Cardiomyopathy, Congestive in 33 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"Propranolol in dilated cardiomyopathy is associated with significant intolerance."2.68Hemodynamic predictors of early intolerance and long-term effects of propranolol in dilated cardiomyopathy. ( Bhargava, B; Chopra, P; Kamlakar, T; Talwar, KK; Upasani, PT; Verma, S, 1996)
"In patients with dilated cardiomyopathy the beta-adrenergic responsiveness of the myocardium is diminished."2.41The beta-adrenergic receptors. ( Wallukat, G, 2002)
"Volume reduction surgery for dilated cardiomyopathy has not yielded predictable outcomes."1.32Importance of preserving the apex and plication of the base in left ventricular volume reduction surgery. ( Komeda, M; Koyama, T; Nishimura, K; Soga, Y; Ueyama, K; Unimonh, O, 2003)
"Pretreatment with propranolol almost completely inhibited increased plasma free fatty acid and NA levels associated with adrenaline infusion, suggesting that adrenaline increases plasma free fatty acid and NA levels via the stimulation of beta-adrenoceptors in vehicle-treated rabbits."1.30Effects of adrenaline infusion on plasma lipids and noradrenaline levels in rabbits with adriamycin-induced cardiomyopathy. ( Fujiwara, H; Ito, H; Kakami, M; Koshiji, M; Minatoguchi, S; Seishima, M; Uno, Y; Yokoyama, H, 1997)
"This child developed significant acute dilated cardiomyopathy and severe CNS depression 2 hours after ingesting 3200 mg of propranolol."1.30Acute dilated cardiomyopathy and central nervous system toxicity following propranolol intoxication. ( Lifshitz, M; Zalzstein, E; Zucker, N, 1999)
"Propranolol treatment, which can induce cardiac depression in the normal heart, actually prevented cardiac dilation and the depressed left ventricular function characteristic of older TG mice, and abolished premature mortality."1.30Beta-adrenergic receptor blockade arrests myocyte damage and preserves cardiac function in the transgenic G(salpha) mouse. ( Asai, K; Bishop, S; Geng, YJ; Homcy, CJ; Ishikawa, Y; Shannon, RP; Takagi, G; Vatner, DE; Vatner, SF; Wagner, TE; Yang, GP, 1999)
"Carvedilol is a high-affinity, slightly beta 1-selective competitive beta-blocking agent, with a KD for beta 1-receptors of approximately 4-5 nM and a selectivity of sixfold to 39-fold for beta 1-receptors rather than beta 2-receptors, depending on the method used to assess subtype potency."1.28Receptor pharmacology of carvedilol in the human heart. ( Bristow, MR; Handwerger, D; Klein, J; Larrabee, P; Minobe, W; Müller-Beckmann, B; Port, JD; Roden, R; Skerl, L, 1992)
"In furazolidone-treated birds with resultant cardiac dilation there was myocyte hypertrophy, enlargement of nuclei and reorientation of subepicardial myocardial fibres."1.28Morphological changes associated with furazolidone-induced cardiomyopathy: effects of digoxin and propranolol. ( Gwathmey, JK, 1991)
"Two cases of dilated cardiomyopathy with incessant supraventricular tachycardia were treated with beta-blockade."1.28Two cases of dilated cardiomyopathy associated with incessant supraventricular tachycardia who showed a favorable response to beta-blockade. ( Ishii, M; Ishikawa, T; Kimura, K; Kobayashi, K; Kuji, N; Sano, T; Sugimoto, K; Yoshimura, H, 1990)
"Chronic treatment of heart failure patients with beta-adrenoceptor antagonists leads to an up-regulation of cardiac beta-adrenoceptors, but in a subtype-selective fashion: beta 1-selective antagonists increase only cardiac beta 1-adrenoceptors, whereas non-selective antagonists increase both beta 1- and beta 2-adrenoceptors."1.28Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors. ( Borst, HG; Brodde, OE; Maier, W; Michel, MC; Zerkowski, HR, 1989)
"Young turkeys inbred for congestive cardiomyopathy (CCM) were treated with propranolol prior to the development of cardiac enlargement."1.27Effect of early propranolol treatment in an animal model of congestive cardiomyopathy. II. beta-adrenergic receptors and left ventricular function. ( Einzig, S; Noren, GR; Rublein, TG; Staley, NA, 1984)
"Propranolol treated inbred birds showed a significantly reduced mortality from 5 to 15 days of age when compared with untreated inbred birds."1.27Effect of early propranolol treatment in an animal model of congestive cardiomyopathy: I Mortality and Ca2+ transport in sarcoplasmic reticulum. ( Einzig, S; Noren, GR; Rublein, TG; Staley, NA, 1984)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199010 (30.30)18.7374
1990's12 (36.36)18.2507
2000's8 (24.24)29.6817
2010's3 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vikhorev, PG1
Song, W1
Wilkinson, R1
Copeland, O1
Messer, AE1
Ferenczi, MA1
Marston, SB1
Mascaro-Blanco, A1
Alvarez, K1
Yu, X1
Lindenfeld, J2
Olansky, L1
Lyons, T1
Duvall, D1
Heuser, JS1
Gosmanova, A1
Rubenstein, CJ1
Cooper, LT1
Kem, DC1
Cunningham, MW1
Tan, F1
Thai, AC1
Cheah, WK1
Mukherjee, JJ1
Isserlin, R1
Merico, D1
Alikhani-Koupaei, R1
Gramolini, A1
Bader, GD1
Emili, A1
McEntee, RK1
Coyle, D1
Meyer, M1
Wallukat, G1
Koyama, T1
Nishimura, K1
Soga, Y1
Unimonh, O1
Ueyama, K1
Komeda, M1
Tidholm, A1
Falk, T1
Gundler, S1
Svensson, H1
Ablad, B1
Sylvén, C1
Preobrazhenskiĭ, DV1
Staley, NA2
Noren, GR2
Einzig, S2
Rublein, TG2
Sato, H1
Hori, M1
Ozaki, H1
Yokoyama, H2
Imai, K1
Morikawa, M1
Takeda, H1
Inoue, M1
Kamada, T1
Erlebacher, JA1
Bhardwaj, M1
Suresh, A1
Leber, GB1
Goldweit, RS1
Koumi, S1
Backer, CL1
Arentzen, CE1
Sato, R1
Talwar, KK1
Bhargava, B1
Upasani, PT1
Verma, S1
Kamlakar, T1
Chopra, P1
Minatoguchi, S1
Uno, Y1
Seishima, M1
Koshiji, M1
Kakami, M1
Ito, H1
Fujiwara, H1
Lifshitz, M1
Zucker, N1
Zalzstein, E1
Asai, K1
Yang, GP1
Geng, YJ1
Takagi, G1
Bishop, S1
Ishikawa, Y1
Shannon, RP1
Wagner, TE1
Vatner, DE1
Homcy, CJ1
Vatner, SF1
Noori, A1
Wolfel, E1
Ferguson, D1
Bristow, MR2
Lowes, BD1
Khalil, A1
Chawla, K1
Chakravarti, A1
Chiale, PA1
Ferrari, I1
Mahler, E1
Vallazza, MA1
Elizari, MV1
Rosenbaum, MB1
Levin, MJ1
Yamashita, T1
Gasilin, VS1
Piskareva, IN1
Rozova, NK1
Potapkina, IN1
Bubnov, IuP1
Zvereva, LV1
Larrabee, P1
Minobe, W1
Roden, R1
Skerl, L1
Klein, J1
Handwerger, D1
Port, JD1
Müller-Beckmann, B1
Gwathmey, JK1
Yoshimura, H1
Ishikawa, T1
Kuji, N1
Sugimoto, K1
Kimura, K1
Sano, T1
Kobayashi, K1
Ishii, M1
Brodde, OE1
Zerkowski, HR1
Borst, HG1
Maier, W1
Michel, MC1
Popov, VG1
Sidorenko, BA1
Gruzdev, AK1
Sadowski, D1
Cujec, B1
McMeekin, JD1
Wilson, TW1
Ruth-Maurin, A1
Bilińska, ZT1
Golf, S1
Jahnsen, T1
Simonsen, S1
Attramadal, A1
Hansson, V1
Shanes, JG1
Wolfkiel, C1
Ghali, J1
Dierenfeldt, BJ1
Kondos, GT1
Bauman, JL1
Chopra, A1
Chib, P1
Singh, RP1
Prabhakaran, SN1

Reviews

3 reviews available for propranolol and Cardiomyopathy, Congestive

ArticleYear
The beta-adrenergic receptors.
    Herz, 2002, Volume: 27, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Arrhythmias, Cardiac; Autoantibodies; Calciu

2002
[New therapeutic possibilities of propranolol].
    Terapevticheskii arkhiv, 1984, Volume: 56, Issue:12

    Topics: Antithyroid Agents; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases;

1984
[Adrenergic beta receptor blockaders in congestive heart failure: potential mechanisms of their action].
    Kardiologia polska, 1988, Volume: 31, Issue:6

    Topics: Cardiomyopathy, Dilated; Heart Ventricles; Humans; Metoprolol; Propranolol; Receptors, Adrenergic, b

1988

Trials

3 trials available for propranolol and Cardiomyopathy, Congestive

ArticleYear
Effect of thyroid hormone supplementation on survival of euthyroid dogs with congestive heart failure due to systolic myocardial dysfunction: a double-blind, placebo-controlled trial.
    Research in veterinary science, 2003, Volume: 75, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Cardiotonic Agents; Digoxin; Diuretics; Do

2003
Hemodynamic predictors of early intolerance and long-term effects of propranolol in dilated cardiomyopathy.
    Journal of cardiac failure, 1996, Volume: 2, Issue:4

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Cardiomyopathy, Dilated; Chi-Square Distributi

1996
Acute hemodynamic effects of pindolol and propranolol in patients with dilated cardiomyopathy: relevance of intrinsic sympathomimetic activity.
    American heart journal, 1988, Volume: 116, Issue:5 Pt 1

    Topics: Adult; Cardiac Catheterization; Cardiomyopathy, Dilated; Double-Blind Method; Female; Hemodynamics;

1988

Other Studies

27 other studies available for propranolol and Cardiomyopathy, Congestive

ArticleYear
The dilated cardiomyopathy-causing mutation ACTC E361G in cardiac muscle myofibrils specifically abolishes modulation of Ca(2+) regulation by phosphorylation of troponin I.
    Biophysical journal, 2014, Nov-18, Volume: 107, Issue:10

    Topics: Actins; Animals; Calcium; Cardiomyopathy, Dilated; Carrier Proteins; Cyclic AMP-Dependent Protein Ki

2014
Consequences of unlocking the cardiac myosin molecule in human myocarditis and cardiomyopathies.
    Autoimmunity, 2008, Volume: 41, Issue:6

    Topics: Adrenergic beta-2 Receptor Antagonists; Amino Acid Sequence; Autoantibodies; Cardiac Myosins; Cardio

2008
Unusual presentation of pheochromocytoma with ischemic sigmoid colitis and stenosis.
    Southern medical journal, 2009, Volume: 102, Issue:10

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; C

2009
Pathway analysis of dilated cardiomyopathy using global proteomic profiling and enrichment maps.
    Proteomics, 2010, Volume: 10, Issue:6

    Topics: Animals; Apoptosis; Cardiomyopathy, Dilated; Caspase 3; Databases, Protein; Gelsolin; Gene Expressio

2010
Severe dilated cardiomyopathy after propranolol treatment in an undiagnosed adrenal pheochromocytoma.
    Circulation. Heart failure, 2011, Volume: 4, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Adult; Cardiomyopathy, Dilated; Diagnostic Err

2011
Importance of preserving the apex and plication of the base in left ventricular volume reduction surgery.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 125, Issue:3

    Topics: Acute Disease; Animals; Cardiac Output; Cardiac Volume; Cardiomyopathy, Dilated; Diastole; Dogs; Ech

2003
Effect of early propranolol treatment in an animal model of congestive cardiomyopathy. II. beta-adrenergic receptors and left ventricular function.
    Cardiovascular research, 1984, Volume: 18, Issue:9

    Topics: Animals; Cardiomyopathy, Dilated; Disease Models, Animal; Heart; Heart Failure; Heart Ventricles; Pr

1984
Effect of early propranolol treatment in an animal model of congestive cardiomyopathy: I Mortality and Ca2+ transport in sarcoplasmic reticulum.
    Cardiovascular research, 1984, Volume: 18, Issue:6

    Topics: Animals; Biological Transport, Active; Calcium; Cardiomyopathy, Dilated; Disease Models, Animal; Hea

1984
Exercise-induced upward shift of diastolic left ventricular pressure-volume relation in patients with dilated cardiomyopathy. Effects of beta-adrenoceptor blockade.
    Circulation, 1993, Volume: 88, Issue:5 Pt 1

    Topics: Adrenergic beta-Antagonists; Adult; Aortic Valve Insufficiency; Blood Pressure; Blood Volume; Cardia

1993
Beta-blocker treatment of idiopathic and ischemic dilated cardiomyopathy in patients with ejection fractions < or = 20%.
    The American journal of cardiology, 1993, Jun-15, Volume: 71, Issue:16

    Topics: Aged; Cardiomyopathy, Dilated; Female; Humans; Male; Metoprolol; Middle Aged; Propranolol; Stroke Vo

1993
beta-Adrenergic modulation of the inwardly rectifying potassium channel in isolated human ventricular myocytes. Alteration in channel response to beta-adrenergic stimulation in failing human hearts.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:6

    Topics: Adrenergic beta-Agonists; Adult; Alkaline Phosphatase; Analysis of Variance; Barium; Bucladesine; Ca

1995
Effects of adrenaline infusion on plasma lipids and noradrenaline levels in rabbits with adriamycin-induced cardiomyopathy.
    Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:7

    Topics: Animals; Blood Pressure; Cardiomyopathy, Dilated; Cholesterol; Cholesterol, HDL; Doxorubicin; Epinep

1997
Acute dilated cardiomyopathy and central nervous system toxicity following propranolol intoxication.
    Pediatric emergency care, 1999, Volume: 15, Issue:4

    Topics: Acute Disease; Adolescent; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Antidotes; Cardiom

1999
Beta-adrenergic receptor blockade arrests myocyte damage and preserves cardiac function in the transgenic G(salpha) mouse.
    The Journal of clinical investigation, 1999, Volume: 104, Issue:5

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiomyopathy, Dilated; Cy

1999
Beta-blockade in adriamycin-induced cardiomyopathy.
    Journal of cardiac failure, 2000, Volume: 6, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antineoplastic Agents; Carbazoles; Cardiomyopathies; Cardi

2000
Dilated cardiomyopathy : clinical profile and treatment.
    Indian pediatrics, 2000, Volume: 37, Issue:11

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiomyopathy, Di

2000
Differential profile and biochemical effects of antiautonomic membrane receptor antibodies in ventricular arrhythmias and sinus node dysfunction.
    Circulation, 2001, Apr-03, Volume: 103, Issue:13

    Topics: Adult; Aged; Amino Acid Sequence; Animals; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atropine; Autoan

2001
[Electromechanical responsiveness to alpha 1-adrenoceptor and angiotensin II receptor stimulation in the ventricular myocardium of hypertrophied and dilated cardiomyopathic Syrian hamsters].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1992, Volume: 67, Issue:6

    Topics: Action Potentials; Angiotensin II; Animals; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; C

1992
[Several aspects of the diagnosis of cardiomyopathies and patient management policy].
    Rossiiskii meditsinskii zhurnal : organ Ministerstva zdravookhraneniia RSFSR, 1992, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Cardiomyopathie

1992
Receptor pharmacology of carvedilol in the human heart.
    Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Binding, Competitive; Carbazoles; Cardiomyopat

1992
Morphological changes associated with furazolidone-induced cardiomyopathy: effects of digoxin and propranolol.
    Journal of comparative pathology, 1991, Volume: 104, Issue:1

    Topics: Animals; Cardiomyopathy, Dilated; Digoxin; Furazolidone; Heart; Propranolol; Turkeys

1991
Two cases of dilated cardiomyopathy associated with incessant supraventricular tachycardia who showed a favorable response to beta-blockade.
    Heart and vessels. Supplement, 1990, Volume: 5

    Topics: Adult; Cardiomyopathy, Dilated; Humans; Male; Propranolol; Tachycardia, Supraventricular

1990
Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors.
    European heart journal, 1989, Volume: 10 Suppl B

    Topics: Adolescent; Adult; Cardiomyopathy, Dilated; Child; Child, Preschool; Coronary Disease; Heart Failure

1989
[Actual problems of the treatment of acute myocardial infarction].
    Kardiologiia, 1989, Volume: 29, Issue:10

    Topics: Aged; Cardiomyopathy, Dilated; Drug Evaluation; Drug Therapy, Combination; Hemodynamics; Humans; Mid

1989
Reversibility of catecholamine-induced cardiomyopathy in a woman with pheochromocytoma.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1989, Nov-01, Volume: 141, Issue:9

    Topics: Cardiomyopathy, Dilated; Catecholamines; Female; Humans; Middle Aged; Phenoxybenzamine; Pheochromocy

1989
Catecholamine-responsive adenylate cyclase activity in human endomyocardial biopsies. Individual sensitivity to isoproterenol stimulation and propranolol inhibition.
    Scandinavian journal of clinical and laboratory investigation, 1985, Volume: 45, Issue:1

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Cardiomyopathy, Dil

1985
Beta-blockade-vasodilator therapy in peripartum cardiomyopathy.
    The Journal of the Association of Physicians of India, 1986, Volume: 34, Issue:7

    Topics: Adolescent; Cardiomyopathy, Dilated; Female; Humans; Hydralazine; Pregnancy; Propranolol

1986