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propranolol and Cardiac Remodeling, Ventricular

propranolol has been researched along with Cardiac Remodeling, Ventricular in 20 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"193 patients with their first non-Q-wave myocardial infarction (NQMI) were examined with the aim of studying the functional features of NQMI and estimate the influence of pre-hospital treatment with propranalol (PP), heparin and aspirin."7.73[Functional features of acute non-Q-wave myocardial infarction and the influence of pre-hospital treatment with propranalol, heparin and aspirin on the prognosis of the disease]. ( Baltabaev, TB; Beĭshenkulov, MT; Kudaĭbergenova, NT, 2005)
"Although carvedilol attenuates left ventricular (LV) remodeling in coronary occlusion-reperfusion, it is not known whether it attenuates ischemic LV remodeling because of coronary stenosis (CS) or permanent coronary occlusion (CO)."7.71Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats. ( Maehara, K; Maruyama, Y; Sakabe, A; Yaoita, H, 2002)
"The effects of propranolol and verapamil on contractile dysfunction, subcellular remodeling and changes in gene expression in cardiac hypertrophy due to pressure overload were examined."7.70Attenuation of changes in sarcoplasmic reticular gene expression in cardiac hypertrophy by propranolol and verapamil. ( Dhalla, NS; Elmoselhi, AB; Goel, R; Sentex, E; Takeo, S; Wang, J, 2000)
"Insulin resistance was induced by HFrHFD feeding for 16 weeks."5.62Propranolol and low-dose isoproterenol ameliorate insulin resistance, enhance β-arrestin2 signaling, and reduce cardiac remodeling in high-fructose, high-fat diet-fed mice: Comparative study with metformin. ( Ahmed, HMS; Ibrahim, IAAE; Ibrahim, WS; Mahmoud, AAA; Mahmoud, MF, 2021)
"In propranolol-treated rats, hypertrophy of the LV septum, papillary muscle, and right ventricle were similar to those of the infarcted control."5.31Effects of prolonged propranolol treatment on left ventricular remodeling and oxidative stress after myocardial infarction in rats. ( Bonnefont-Rousselot, D; Komajda, M; Lechat, P; Mansuy, P; Mougenot, N; Raillecove, F; Ramirez-Gil, JF, 2000)
" We compared the data from 8 infants with severe congestive heart failure due to left-to-right shunts, who received digoxin and diuretics alone, to 9 infants who received additional treatment with propranolol."5.10Effects of therapeutic beta blockade on myocardial function and cardiac remodelling in congenital cardiac disease. ( Buchhorn, R; Fielitz, J; Hetzer, R; Hulpke-Wette, M; Pregla, R; Regitz-Zagrosek, V; Ross, RD; Ruschewski, W, 2003)
" A rat model of thyrotoxicosis was established by daily intraperitoneal injections of L-thyroxine (T(4), 100 μg/kg) for 4 weeks."3.78Irbesartan prevents myocardial remodeling in experimental thyrotoxic cardiomyopathy. ( Cho, KI; Choi, BG; Jeon, YK; Kang, JH; Kim, BH; Kim, IJ; Kim, JY; Kim, SJ; Kim, SM; Kim, SS; Kim, YK, 2012)
" Three weeks after inducing myocardial infarction (MI), rats were treated daily with or without 20 and 75 mg/kg atenolol, a selective β(1) -AR antagonist, or propranolol, a non-selective β-AR antagonist, for 5 weeks."3.77β-adrenergic blockade attenuates cardiac dysfunction and myofibrillar remodelling in congestive heart failure. ( Dhalla, NS; Elimban, V; Machackova, J; Sanganalmath, SK, 2011)
"193 patients with their first non-Q-wave myocardial infarction (NQMI) were examined with the aim of studying the functional features of NQMI and estimate the influence of pre-hospital treatment with propranalol (PP), heparin and aspirin."3.73[Functional features of acute non-Q-wave myocardial infarction and the influence of pre-hospital treatment with propranalol, heparin and aspirin on the prognosis of the disease]. ( Baltabaev, TB; Beĭshenkulov, MT; Kudaĭbergenova, NT, 2005)
"Although carvedilol attenuates left ventricular (LV) remodeling in coronary occlusion-reperfusion, it is not known whether it attenuates ischemic LV remodeling because of coronary stenosis (CS) or permanent coronary occlusion (CO)."3.71Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats. ( Maehara, K; Maruyama, Y; Sakabe, A; Yaoita, H, 2002)
"The effects of propranolol and verapamil on contractile dysfunction, subcellular remodeling and changes in gene expression in cardiac hypertrophy due to pressure overload were examined."3.70Attenuation of changes in sarcoplasmic reticular gene expression in cardiac hypertrophy by propranolol and verapamil. ( Dhalla, NS; Elmoselhi, AB; Goel, R; Sentex, E; Takeo, S; Wang, J, 2000)
"To investigate the effects of perindopril, propranolol, and dihydrochlorothiazide on artery wall thickening, left ventricular hypertrophy, and cardiac fibrosis in spontaneously hypertensive rats (SHR)."3.70Effects of perindopril, propranolol, and dihydrochlorothiazide on cardiovascular remodelling in spontaneously hypertensive rats. ( Chen, DG; Chen, SC; Rui, HB; Su, JZ; Wang, HJ; Wang, XY; Wu, KG, 1999)
"Insulin resistance was induced by HFrHFD feeding for 16 weeks."1.62Propranolol and low-dose isoproterenol ameliorate insulin resistance, enhance β-arrestin2 signaling, and reduce cardiac remodeling in high-fructose, high-fat diet-fed mice: Comparative study with metformin. ( Ahmed, HMS; Ibrahim, IAAE; Ibrahim, WS; Mahmoud, AAA; Mahmoud, MF, 2021)
"Propranolol treatment normalized also the prolongation of the action potential in papillary muscles from the diabetic rat hearts."1.37Cardioprotective effect of propranolol on diabetes-induced altered intracellular Ca2+ signaling in rat. ( Tuncay, E; Turan, B; Zeydanli, EN, 2011)
"The role of the adrenergic system on ventricular remodeling induced by cigarette smoking is unknown."1.35Effects of the administration of beta-blockers on ventricular remodeling induced by cigarette smoking in rats. ( Azevedo, PS; Campana, AO; Duarte, DR; Matsubara, BB; Matsubara, LS; Minicucci, MF; Oliveira, LC; Paiva, SA; Zornoff, LA, 2009)
"Propranolol treatment of TOT mice reversed the alterations in SERCA and NCX protein levels but not potassium channels."1.32Calcium dynamics in the failing heart: restoration by beta-adrenergic receptor blockade. ( Benkusky, N; Fiset, C; Glascock, B; Lalli, MJ; Periasamy, M; Plank, DM; Ritsu, H; Sussman, MA; Valdivia, HH; Witt, S; Yatani, A, 2003)
"In propranolol-treated rats, hypertrophy of the LV septum, papillary muscle, and right ventricle were similar to those of the infarcted control."1.31Effects of prolonged propranolol treatment on left ventricular remodeling and oxidative stress after myocardial infarction in rats. ( Bonnefont-Rousselot, D; Komajda, M; Lechat, P; Mansuy, P; Mougenot, N; Raillecove, F; Ramirez-Gil, JF, 2000)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.00)18.2507
2000's11 (55.00)29.6817
2010's7 (35.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Ibrahim, WS1
Ahmed, HMS1
Mahmoud, AAA1
Mahmoud, MF1
Ibrahim, IAAE1
Duarte, DR1
Oliveira, LC1
Minicucci, MF1
Azevedo, PS1
Matsubara, BB1
Matsubara, LS1
Campana, AO1
Paiva, SA1
Zornoff, LA1
Machackova, J2
Sanganalmath, SK2
Barta, J1
Dhalla, KS1
Dhalla, NS3
Elimban, V1
Chen, WQ1
Cai, H1
Zhang, C1
Ji, XP1
Zhang, Y1
O-Uchi, J1
Lopes, CM1
Guo, D1
Kassiri, Z1
Basu, R1
Chow, FL1
Kandalam, V1
Damilano, F1
Liang, W1
Izumo, S1
Hirsch, E1
Penninger, JM1
Backx, PH1
Oudit, GY1
Tuncay, E1
Zeydanli, EN1
Turan, B1
Kim, BH1
Cho, KI1
Kim, SM1
Kim, JY1
Choi, BG1
Kang, JH1
Jeon, YK1
Kim, SS1
Kim, SJ1
Kim, YK1
Kim, IJ1
Plank, DM1
Yatani, A1
Ritsu, H1
Witt, S1
Glascock, B1
Lalli, MJ1
Periasamy, M1
Fiset, C1
Benkusky, N1
Valdivia, HH1
Sussman, MA1
Buchhorn, R1
Hulpke-Wette, M1
Ruschewski, W1
Ross, RD1
Fielitz, J1
Pregla, R1
Hetzer, R1
Regitz-Zagrosek, V1
Marano, G1
Palazzesi, S1
Vergari, A1
Catalano, L1
Gaudi, S1
Testa, C1
Canese, R1
Carpinelli, G1
Podo, F1
Ferrari, AU1
Hardt, SE1
Tomita, H1
Katus, HA1
Sadoshima, J1
Beĭshenkulov, MT1
Kudaĭbergenova, NT1
Baltabaev, TB1
Takahashi, T1
Tang, T1
Lai, NC1
Roth, DM1
Rebolledo, B1
Saito, M1
Lew, WY1
Clopton, P1
Hammond, HK1
Mansuy, P1
Mougenot, N1
Ramirez-Gil, JF1
Bonnefont-Rousselot, D1
Raillecove, F1
Komajda, M1
Lechat, P1
Takeo, S1
Elmoselhi, AB1
Goel, R1
Sentex, E1
Wang, J1
Su, JZ1
Chen, SC1
Wu, KG1
Chen, DG1
Rui, HB1
Wang, XY1
Wang, HJ1
Yaoita, H1
Sakabe, A1
Maehara, K1
Maruyama, Y1
Doi, M1
Yano, M1
Kobayashi, S1
Kohno, M2
Tokuhisa, T1
Okuda, S1
Suetsugu, M1
Hisamatsu, Y1
Ohkusa, T1
Matsuzaki, M1

Trials

1 trial available for propranolol and Cardiac Remodeling, Ventricular

ArticleYear
Effects of therapeutic beta blockade on myocardial function and cardiac remodelling in congenital cardiac disease.
    Cardiology in the young, 2003, Volume: 13, Issue:1

    Topics: Adrenergic beta-Antagonists; Digoxin; Diuretics; Dose-Response Relationship, Drug; Drug Administrati

2003

Other Studies

19 other studies available for propranolol and Cardiac Remodeling, Ventricular

ArticleYear
Propranolol and low-dose isoproterenol ameliorate insulin resistance, enhance β-arrestin2 signaling, and reduce cardiac remodeling in high-fructose, high-fat diet-fed mice: Comparative study with metformin.
    Life sciences, 2021, Dec-01, Volume: 286

    Topics: Animals; beta-Arrestin 2; Blood Glucose; Diet, High-Fat; Fructose; Glucose; Heart; Insulin; Insulin

2021
Effects of the administration of beta-blockers on ventricular remodeling induced by cigarette smoking in rats.
    Arquivos brasileiros de cardiologia, 2009, Volume: 92, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Inhalation Exposure; Male; Models, Animal; Propranolol; Rats;

2009
Amelioration of cardiac remodeling in congestive heart failure by beta-adrenoceptor blockade is associated with depression in sympathetic activity.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Depression, Chemical; Electrocardiog

2010
β-adrenergic blockade attenuates cardiac dysfunction and myofibrillar remodelling in congestive heart failure.
    Journal of cellular and molecular medicine, 2011, Volume: 15, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blotting, Northern; Ca(2+) Mg(2+)-ATPase; Dose-Respo

2011
Is overall blockade superior to selective blockade of adrenergic receptor subtypes in suppressing left ventricular remodeling in spontaneously hypertensive rats?
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:10

    Topics: Adrenergic Antagonists; Animals; Apoptosis; Bisoprolol; Blood Pressure; Carbazoles; Carvedilol; Dise

2010
Combined blockade of β- and α₁-adrenoceptors in left ventricular remodeling induced by hypertension: beneficial or not?
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:10

    Topics: Adrenergic Antagonists; Animals; Bisoprolol; Carbazoles; Carvedilol; Disease Models, Animal; Humans;

2010
Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress.
    Circulation research, 2010, Nov-12, Volume: 107, Issue:10

    Topics: Adrenergic beta-Antagonists; Animals; Antigens, CD; beta Catenin; Biomechanical Phenomena; Cadherins

2010
Cardioprotective effect of propranolol on diabetes-induced altered intracellular Ca2+ signaling in rat.
    Journal of bioenergetics and biomembranes, 2011, Volume: 43, Issue:6

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Antibiotics, Antineoplastic; Calcium Signaling;

2011
Irbesartan prevents myocardial remodeling in experimental thyrotoxic cardiomyopathy.
    Endocrine journal, 2012, Volume: 59, Issue:10

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Cardiomyopathies; Echocardiogr

2012
Calcium dynamics in the failing heart: restoration by beta-adrenergic receptor blockade.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:1

    Topics: Adrenergic beta-Antagonists; Aniline Compounds; Animals; Blotting, Western; Calcium; Calcium Signali

2003
Inhibition of left ventricular remodelling preserves chamber systolic function in pressure-overloaded mice.
    Pflugers Archiv : European journal of physiology, 2003, Volume: 446, Issue:4

    Topics: Animals; Aorta; Echocardiography; Hemodynamics; Hypertrophy, Left Ventricular; Magnetic Resonance Im

2003
Phosphorylation of eukaryotic translation initiation factor 2Bepsilon by glycogen synthase kinase-3beta regulates beta-adrenergic cardiac myocyte hypertrophy.
    Circulation research, 2004, Apr-16, Volume: 94, Issue:7

    Topics: Adenoviridae; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Atri

2004
[Functional features of acute non-Q-wave myocardial infarction and the influence of pre-hospital treatment with propranalol, heparin and aspirin on the prognosis of the disease].
    Klinicheskaia meditsina, 2005, Volume: 83, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Anticoagulants; Aspirin; Data Interpretation, Statistical; Elect

2005
Increased cardiac adenylyl cyclase expression is associated with increased survival after myocardial infarction.
    Circulation, 2006, Aug-01, Volume: 114, Issue:5

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Apoptosis; Calcium; Cyclic AMP; Female; Gen

2006
Effects of prolonged propranolol treatment on left ventricular remodeling and oxidative stress after myocardial infarction in rats.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Heart Failure; Male; Muscle Contraction; Myocardial Infarction; Oxi

2000
Attenuation of changes in sarcoplasmic reticular gene expression in cardiac hypertrophy by propranolol and verapamil.
    Molecular and cellular biochemistry, 2000, Volume: 213, Issue:1-2

    Topics: Adenosine Triphosphatases; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blotting,

2000
Effects of perindopril, propranolol, and dihydrochlorothiazide on cardiovascular remodelling in spontaneously hypertensive rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:10

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Age

1999
Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats.
    Circulation, 2002, Feb-26, Volume: 105, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Ascorbic Acid; Carbazoles; Cardi

2002
Propranolol prevents the development of heart failure by restoring FKBP12.6-mediated stabilization of ryanodine receptor.
    Circulation, 2002, Mar-19, Volume: 105, Issue:11

    Topics: Adrenergic beta-Antagonists; Animals; Calcium; Cardiac Pacing, Artificial; Diastole; Disease Models,

2002