Page last updated: 2024-11-03

propranolol and Brain Neoplasms

propranolol has been researched along with Brain Neoplasms in 27 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
"In has been found that sphingosine, propranolol, imipramine and phorbol ester (12-O-tetradecanoylphorbol-13-acetate, TPA) have a stimulatory effect on phospholipase D activity in glioma C6 cells."7.70Different regulation of phospholipase D activity in glioma C6 cells by sphingosine, propranolol, imipramine and phorbol ester. ( Barańska, J; Bobeszko, M; Dygas, A; Nalepa, I, 2000)
"Malignant gliomas have a highly immune suppressive tumor microenvironment (TME) which renders them largely unresponsive to conventional therapeutics."5.72Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses. ( Ammons, DT; Boss, MK; Chow, L; Dow, S; Frank, C; Griffin, JF; Guth, A; Kurihara, J; MacQuiddy, B; Makii, R; Marolf, AJ; McGrath, S; Packer, RA; Regan, DP; Rozental, AJ, 2022)
"We present a one-month old boy with an intracranial infantile hemangioma treated with propranolol."4.93Beta Blockade as Treatment for Intracranial Infantile Hemangioma: Case Report and Literature Review. ( Friedman, N; Golden, A; Kang, E; Mamoun, I; Tamburro, J, 2016)
" Rat C6 glioma cells were stimulated with isoproterenol and the protein lysates were resolved by 2-DGE."3.70Probing for drug-induced multiplex signal transduction pathways using high resolution two-dimensional gel electrophoresis: application to beta-adrenoceptor stimulation in the rat C6 glioma cell. ( Khawaja, XZ; Storm, SM, 1999)
"In has been found that sphingosine, propranolol, imipramine and phorbol ester (12-O-tetradecanoylphorbol-13-acetate, TPA) have a stimulatory effect on phospholipase D activity in glioma C6 cells."3.70Different regulation of phospholipase D activity in glioma C6 cells by sphingosine, propranolol, imipramine and phorbol ester. ( Barańska, J; Bobeszko, M; Dygas, A; Nalepa, I, 2000)
"Fetal brain tumors are rare."2.53A case of giant fetal intracranial capillary hemangioma cured with propranolol. ( Campos, HG; Cavalheiro, S; Silva da Costa, MD, 2016)
"Malignant gliomas have a highly immune suppressive tumor microenvironment (TME) which renders them largely unresponsive to conventional therapeutics."1.72Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses. ( Ammons, DT; Boss, MK; Chow, L; Dow, S; Frank, C; Griffin, JF; Guth, A; Kurihara, J; MacQuiddy, B; Makii, R; Marolf, AJ; McGrath, S; Packer, RA; Regan, DP; Rozental, AJ, 2022)
"Propranolol has recently been shown to be effective in the treatment of infantile hemangioma, a close pathologic counterpart of cavernous malformations."1.43Propranolol Treatment of Cavernous Malformations with Symptomatic Hemorrhage. ( Filippidis, AS; Kalani, MYS; Spetzler, RF; Zabramski, JM, 2016)
"Two case reports are described, both breast carcinoma patients with metastatic disease."1.27A call for caution in the use of aminoglutethimide: negative interactions with dexamethasone and beta blocker treatment. ( Baerwald, H; Catane, R; Halpern, J, 1984)
"The atropine test was found to be an efficient and simple diagnostic aid in cases of brain death."1.25Electrocardiographic findings in brain death; description and presumed mechanism. ( Drory, Y; Kellermann, JJ; Kosary, IZ; Ouaknine, G, 1975)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.93)18.7374
1990's4 (14.81)18.2507
2000's3 (11.11)29.6817
2010's9 (33.33)24.3611
2020's4 (14.81)2.80

Authors

AuthorsStudies
Haugaard-Kedström, LM1
Clemmensen, LS1
Sereikaite, V1
Jin, Z1
Fernandes, EFA1
Wind, B1
Abalde-Gil, F1
Daberger, J1
Vistrup-Parry, M1
Aguilar-Morante, D1
Leblanc, R1
Egea-Jimenez, AL1
Albrigtsen, M1
Jensen, KE1
Jensen, TMT1
Ivarsson, Y1
Vincentelli, R1
Hamerlik, P1
Andersen, JH1
Zimmermann, P1
Lee, W1
Strømgaard, K1
Shenkar, R1
Moore, T1
Benavides, C1
Lightle, R1
Detter, MR1
Hobson, N1
Girard, R1
DeBiasse, D1
Patrucco, M1
Gallione, C1
Zabramski, JM2
Marchuk, DA1
Awad, IA1
Zamil, DH1
Fernandez, JK1
Brown, DN1
Kralik, SF1
Herd, TJ1
Ammons, DT1
Guth, A1
Rozental, AJ1
Kurihara, J1
Marolf, AJ1
Chow, L1
Griffin, JF1
Makii, R1
MacQuiddy, B1
Boss, MK1
Regan, DP1
Frank, C1
McGrath, S1
Packer, RA1
Dow, S1
Kaliaperumal, C1
Apra, C1
Dumot, C1
Bourdillon, P1
Pelissou-Guyotat, I1
Berti, I1
Marchetti, F1
Skabar, A1
Zennaro, F1
Zanon, D1
Ventura, A1
Miquel, J1
Bruneau, B1
Dupuy, A1
Kalani, MYS1
Filippidis, AS1
Spetzler, RF1
Cavalheiro, S1
Campos, HG1
Silva da Costa, MD1
Choy, C1
Raytis, JL1
Smith, DD1
Duenas, M1
Neman, J1
Jandial, R1
Lew, MW1
Kang, E1
Friedman, N1
Mamoun, I1
Tamburro, J1
Golden, A1
Annabi, B1
Lachambre, MP1
Plouffe, K1
Moumdjian, R1
Béliveau, R1
Moschovi, M1
Alexiou, GA1
Stefanaki, K1
Tourkantoni, N1
Prodromou, N1
Oh, SJ1
Hong, YK1
Song, EK1
Halpern, J1
Catane, R1
Baerwald, H1
Caciagli, F1
Ciccarelli, R1
Ciancetta, S1
Di Iorio, P1
Caciagli, P1
Eggers, C1
Felice, KJ1
Grunnet, ML1
Canova, C1
Baudet, C1
Chevalier, G1
Brachet, P1
Wion, D1
Woiciechowsky, C1
Asadullah, K1
Nestler, D1
Eberhardt, B1
Platzer, C1
Schöning, B1
Glöckner, F1
Lanksch, WR1
Volk, HD1
Döcke, WD1
Storm, SM1
Khawaja, XZ1
Bobeszko, M1
Dygas, A1
Nalepa, I1
Barańska, J1
Perkins, JP1
Moore, MM1
Kalisker, A1
Su, YF1
Oey, J1
Drory, Y1
Ouaknine, G1
Kosary, IZ1
Kellermann, JJ1
Uchida, M1
Yamaoka, H1

Reviews

4 reviews available for propranolol and Brain Neoplasms

ArticleYear
Could propranolol be beneficial in adult cerebral cavernous malformations?
    Neurosurgical review, 2019, Volume: 42, Issue:2

    Topics: Adrenergic beta-Antagonists; Brain Neoplasms; Cardiovascular Agents; Hemangioma, Cavernous, Central

2019
A case of giant fetal intracranial capillary hemangioma cured with propranolol.
    Journal of neurosurgery. Pediatrics, 2016, Volume: 17, Issue:6

    Topics: Adrenergic beta-Antagonists; Brain Neoplasms; Female; Fetal Diseases; Hemangioma, Capillary; Humans;

2016
Beta Blockade as Treatment for Intracranial Infantile Hemangioma: Case Report and Literature Review.
    Pediatric neurology, 2016, Volume: 59

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Antineoplastic Agents; Brain Neoplasms; Hemangiom

2016
Regulation of cyclic AMP content in normal and malignant brain cells.
    Advances in cyclic nucleotide research, 1975, Volume: 5

    Topics: Adenosine; Animals; Brain; Brain Neoplasms; Cerebral Cortex; Cyclic AMP; Hydroxydopamines; Isoproter

1975

Other Studies

23 other studies available for propranolol and Brain Neoplasms

ArticleYear
A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma.
    Journal of medicinal chemistry, 2021, 02-11, Volume: 64, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioblasto

2021
Propranolol as therapy for cerebral cavernous malformations: a cautionary note.
    Journal of translational medicine, 2022, 04-05, Volume: 20, Issue:1

    Topics: Brain Neoplasms; Hemangioma, Cavernous, Central Nervous System; Humans; Magnetic Resonance Imaging;

2022
Intracranial hemangioma-associated cranial nerve VII palsy treated with propranolol in an infant with possible PHACE syndrome.
    Pediatric dermatology, 2022, Volume: 39, Issue:6

    Topics: Brain Neoplasms; Facial Nerve; Facial Paralysis; Female; Hemangioma; Humans; Infant; Propranolol; Sy

2022
Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses.
    Cancer research communications, 2022, Volume: 2, Issue:12

    Topics: Animals; Brain Neoplasms; Cancer Vaccines; Dogs; Glioma; Losartan; Propranolol; Prospective Studies;

2022
Letter to the Editor. Propranolol for pediatric intracerebral cavernomas: unanswered questions.
    Journal of neurosurgery. Pediatrics, 2018, Volume: 21, Issue:2

    Topics: Brain Neoplasms; Child; Hemangioma, Cavernous; Humans; Propranolol

2018
Propranolol for cerebral cavernous angiomatosis: a magic bullet.
    Clinical pediatrics, 2014, Volume: 53, Issue:2

    Topics: Adrenergic beta-Antagonists; Antineoplastic Agents; Brain Neoplasms; Female; Hemangioma, Cavernous,

2014
Successful treatment of multifocal intracerebral and spinal hemangiomas with propranolol.
    Journal of the American Academy of Dermatology, 2014, Volume: 70, Issue:4

    Topics: Brain Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies;

2014
Propranolol Treatment of Cavernous Malformations with Symptomatic Hemorrhage.
    World neurosurgery, 2016, Volume: 88

    Topics: Adrenergic beta-Antagonists; Adult; Brain Neoplasms; Cerebral Hemorrhage; Female; Hemangioma, Cavern

2016
Inhibition of β2-adrenergic receptor reduces triple-negative breast cancer brain metastases: The potential benefit of perioperative β-blockade.
    Oncology reports, 2016, Volume: 35, Issue:6

    Topics: Adrenergic beta-2 Receptor Antagonists; Adult; Aged; Aged, 80 and over; Animals; Brain Neoplasms; Ce

2016
Propranolol adrenergic blockade inhibits human brain endothelial cells tubulogenesis and matrix metalloproteinase-9 secretion.
    Pharmacological research, 2009, Volume: 60, Issue:5

    Topics: Adrenergic beta-Antagonists; Angiogenesis Inhibitors; Animals; Brain; Brain Neoplasms; Cell Line; En

2009
Propranolol treatment for a giant infantile brain cavernoma.
    Journal of child neurology, 2010, Volume: 25, Issue:5

    Topics: Antigens, CD34; Antineoplastic Agents; Blood Vessels; Brain; Brain Neoplasms; Hemangioma, Cavernous,

2010
Paroxysmal autonomic dysregulation with fever that was controlled by propranolol in a brain neoplasm patient.
    The Korean journal of internal medicine, 2007, Volume: 22, Issue:1

    Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Autonomic Nervous System Diseases; Body Temperatur

2007
A call for caution in the use of aminoglutethimide: negative interactions with dexamethasone and beta blocker treatment.
    Journal of medicine, 1984, Volume: 15, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aminoglutethimide; Brain Neoplasms; Breast Neoplasms; Dexamethaso

1984
Adenosine--norepinephrine interactions on cyclic AMP generating system in human tumoral brain slices.
    International journal of tissue reactions, 1982, Volume: 4, Issue:3

    Topics: Adenosine; Adult; Aged; Brain Neoplasms; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug;

1982
[Headache in children].
    Deutsche medizinische Wochenschrift (1946), 1984, Dec-14, Volume: 109, Issue:50

    Topics: Brain Neoplasms; Child; Child, Preschool; Contusions; Dihydroergotamine; Ergotamine; Headache; Human

1984
Inclusion body myositis associated with a severe unilateral levodopa-responsive upper extremity tremor.
    Muscle & nerve, 1996, Volume: 19, Issue:6

    Topics: Action Potentials; Anti-Dyskinesia Agents; Brain Neoplasms; Electromyography; Hand; Humans; Inclusio

1996
Noradrenaline inhibits the programmed cell death induced by 1,25-dihydroxyvitamin D3 in glioma.
    European journal of pharmacology, 1997, Jan-29, Volume: 319, Issue:2-3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Apoptosis; Brain Neoplasms; Calcitri

1997
Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury.
    Nature medicine, 1998, Volume: 4, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Animals; Brain; Brain Injuries; Brain Neoplasms; Brain Ste

1998
Probing for drug-induced multiplex signal transduction pathways using high resolution two-dimensional gel electrophoresis: application to beta-adrenoceptor stimulation in the rat C6 glioma cell.
    Brain research. Molecular brain research, 1999, Jul-23, Volume: 71, Issue:1

    Topics: Animals; Brain Neoplasms; Cyclic AMP; Electrophoresis, Gel, Two-Dimensional; Glioma; Isoproterenol;

1999
Different regulation of phospholipase D activity in glioma C6 cells by sphingosine, propranolol, imipramine and phorbol ester.
    Cellular signalling, 2000, Volume: 12, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Compartmentation; Drug Interactions; Enzyme Activation; Enzyme Inhibi

2000
Noradrenaline-refractoriness in cultured glioma cells.
    Experimental brain research, 1976, Jun-30, Volume: 25, Issue:4

    Topics: Animals; Astrocytoma; Brain Neoplasms; Cells, Cultured; Cyclic AMP; Glioma; Neoplasms, Experimental;

1976
Electrocardiographic findings in brain death; description and presumed mechanism.
    Chest, 1975, Volume: 67, Issue:4

    Topics: Adolescent; Adult; Aged; Atropine; Brain Death; Brain Neoplasms; Child; Child, Preschool; Craniocere

1975
[Effect of beta adrenergic blocking agents on the changes of the ST segment and T wave observed in patients with brain-stem damage].
    Kokyu to junkan. Respiration & circulation, 1972, Volume: 20, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Brain Injuries; Brain Neoplasms; Brain Ste

1972