propranolol has been researched along with Brain Ischemia in 11 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propranolol has been shown to exert a protective effect in experimental myocardial, renal, and early acute focal cerebral ischemia." | 7.67 | Improved neurological outcome in experimental focal cerebral ischemia treated with propranolol. ( Little, JR; Standefer, M, 1986) |
| "Propranolol has been shown to exert a protective effect in experimental myocardial, renal, and early acute focal cerebral ischemia." | 3.67 | Improved neurological outcome in experimental focal cerebral ischemia treated with propranolol. ( Little, JR; Standefer, M, 1986) |
| "Stroke was induced in mice by middle cerebral artery occlusion for 90 minutes, followed by reperfusion." | 1.46 | Hepatic Ketogenesis Induced by Middle Cerebral Artery Occlusion in Mice. ( Berressem, D; Eckert, GP; Klein, J; Koch, K; Konietzka, J; Thinnes, A, 2017) |
| "Rats with cerebral ischemia developed higher blood glucose, and insulin levels, and insulin resistance index, as well as hepatic gluconeogenic enzyme expression compared with the sham-treated group." | 1.40 | Activation of hepatic inflammatory pathways by catecholamines is associated with hepatic insulin resistance in male ischemic stroke rats. ( Chen, CJ; Chuang, YH; Lin, SY; Sheu, WH; Tung, KC; Wang, YY, 2014) |
| "Syncope of patients with bradyarrhythmia is perceived as severe sign of low cardiac output caused by bradycardia and as a major criteria for pacemaker implantation (PMI)." | 1.30 | [Possible contribution of alpha-adrenergic abnormalities to cerebral ischemia in the patients with sinus bradycardia. Analysis by pharmacologic autonomic nervous test]. ( Atarashi, H; Hayakawa, H; Nomura, A; Saitoh, H, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koch, K | 1 |
| Berressem, D | 1 |
| Konietzka, J | 1 |
| Thinnes, A | 1 |
| Eckert, GP | 1 |
| Klein, J | 1 |
| Wang, YY | 1 |
| Lin, SY | 1 |
| Chuang, YH | 1 |
| Sheu, WH | 1 |
| Tung, KC | 1 |
| Chen, CJ | 1 |
| Wong, CH | 1 |
| Jenne, CN | 1 |
| Lee, WY | 1 |
| Léger, C | 1 |
| Kubes, P | 1 |
| Richter, F | 1 |
| Mikulik, O | 1 |
| Ebersberger, A | 1 |
| Schaible, HG | 1 |
| Gupta, MC | 1 |
| Dhamija, JP | 1 |
| Mathur, DS | 1 |
| Sharma, BM | 1 |
| Nomura, A | 1 |
| Saitoh, H | 1 |
| Atarashi, H | 1 |
| Hayakawa, H | 1 |
| Kramer, K | 1 |
| Voss, HP | 1 |
| Grimbergen, JA | 1 |
| Smink, C | 1 |
| Timmerman, H | 1 |
| Bast, A | 1 |
| Shibata, S | 1 |
| Kodama, K | 1 |
| Tominaga, K | 1 |
| Ueki, S | 1 |
| Watanabe, S | 1 |
| O'Shaughnessy, CT | 1 |
| Rothwell, NJ | 1 |
| Shrewsbury-Gee, J | 1 |
| Aleksandrov, PN | 1 |
| Khugaeva, VK | 1 |
| Aleksandrin, VV | 1 |
| Standefer, M | 1 |
| Little, JR | 1 |
11 other studies available for propranolol and Brain Ischemia
| Article | Year |
|---|---|
Hepatic Ketogenesis Induced by Middle Cerebral Artery Occlusion in Mice.
Topics: 3-Hydroxybutyric Acid; Adrenergic beta-Antagonists; Animals; Brain; Brain Ischemia; Citric Acid; Die | 2017 |
Activation of hepatic inflammatory pathways by catecholamines is associated with hepatic insulin resistance in male ischemic stroke rats.
Topics: Adipose Tissue; Alanine Transaminase; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocyt | 2014 |
Functional innervation of hepatic iNKT cells is immunosuppressive following stroke.
Topics: Adrenergic Agents; Animals; Anti-Bacterial Agents; Bacterial Infections; Brain Ischemia; Cell Moveme | 2011 |
Noradrenergic agonists and antagonists influence migration of cortical spreading depression in rat-a possible mechanism of migraine prophylaxis and prevention of postischemic neuronal damage.
Topics: Adrenergic alpha-Agonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Animals; Blood Press | 2005 |
Role of propranolol and aspirin in decreasing platelet aggregation in occlusive cerebrovascular diseases.
Topics: Aspirin; Brain Ischemia; Humans; Platelet Aggregation; Platelet Count; Propranolol | 1983 |
[Possible contribution of alpha-adrenergic abnormalities to cerebral ischemia in the patients with sinus bradycardia. Analysis by pharmacologic autonomic nervous test].
Topics: Adolescent; Adult; Aged; Arrhythmia, Sinus; Atropine; Autonomic Nervous System; Bradycardia; Brain I | 1999 |
Glutathione mobilization during cerebral ischemia and reperfusion in the rat.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Down-Regulation; Erythrocytes; Glutathione; Male; Phentola | 1992 |
Assessment of the role of adrenoceptor function in ischemia-induced impairment of 2-deoxyglucose uptake and CA1 field potential in rat hippocampal slices.
Topics: Action Potentials; Animals; Brain Ischemia; Deoxyglucose; Hippocampus; In Vitro Techniques; Male; Ph | 1992 |
Sympathetically mediated hypermetabolic response to cerebral ischemia in the rat.
Topics: Adipose Tissue, Brown; Animals; Body Temperature; Brain Ischemia; Cerebral Arteries; Ibuprofen; Male | 1990 |
[Obzidan modification of the reaction of the cerebral arterioles to bilateral occlusion of the common carotid arteries].
Topics: Animals; Arterioles; Brain Ischemia; Carotid Arteries; Drug Evaluation, Preclinical; Ligation; Male; | 1988 |
Improved neurological outcome in experimental focal cerebral ischemia treated with propranolol.
Topics: Anesthesia, General; Animals; Brain; Brain Ischemia; Catecholamines; Cats; Cerebrovascular Circulati | 1986 |