propranolol has been researched along with Brain Edema in 6 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesized that early and unselective beta-blockade with propranolol alone or in combination with the alfa2-agonist clonidine would decrease brain edema, blood-brain barrier permeability, and glycocalyx disruption at 24 hours after trauma." | 7.88 | Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat. ( Bentzer, P; Genét, GF; Hansen, MB; Johansson, PI; Ostrowski, SR, 2018) |
| " We hypothesized that early and unselective beta-blockade with propranolol alone or in combination with the alfa2-agonist clonidine would decrease brain edema, blood-brain barrier permeability, and glycocalyx disruption at 24 hours after trauma." | 3.88 | Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat. ( Bentzer, P; Genét, GF; Hansen, MB; Johansson, PI; Ostrowski, SR, 2018) |
| "Brain edema was determined by hemispheric wet-to-dry ratios." | 1.72 | Beta blockade in TBI: Dose-dependent reductions in BBB leukocyte mobilization and permeability in vivo. ( Ahmed, S; Culkin, MC; ElSaadani, M; Georges, A; Jacovides, CL; Kaplan, LJ; Kumar, MA; Lopez, AJ; Pascual, JL; Smith, DH, 2022) |
| "Catecholaminergic polymorphic ventricular tachycardia (VT) is a rare arrhythmogenic disorder, which may cause sudden death and whose relationships with mutations in cardiac ryanodine receptor gene have been recently established." | 1.32 | Catecholaminergic polymorphic ventricular tachycardia: successful emergency treatment with intravenous propranolol. ( Bloise, R; Chiaretti, A; De Rosa, G; Delogu, AB; Piastra, M; Priori, SG, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lopez, AJ | 2 |
| ElSaadani, M | 2 |
| Jacovides, CL | 2 |
| Georges, A | 1 |
| Culkin, MC | 2 |
| Ahmed, S | 1 |
| Kumar, MA | 2 |
| Kaplan, LJ | 2 |
| Smith, DH | 2 |
| Pascual, JL | 2 |
| Georges, AP | 1 |
| Song, H | 1 |
| Genét, GF | 1 |
| Bentzer, P | 1 |
| Hansen, MB | 1 |
| Ostrowski, SR | 1 |
| Johansson, PI | 1 |
| De Rosa, G | 1 |
| Delogu, AB | 1 |
| Piastra, M | 1 |
| Chiaretti, A | 1 |
| Bloise, R | 1 |
| Priori, SG | 1 |
| Ram, Z | 1 |
| Spiegelman, R | 1 |
| Findler, G | 1 |
| Hadani, M | 1 |
| Casacchia, M | 1 |
| Camera, R | 1 |
| Passero, S | 1 |
| Fieschi, C | 1 |
6 other studies available for propranolol and Brain Edema
| Article | Year |
|---|---|
Beta blockade in TBI: Dose-dependent reductions in BBB leukocyte mobilization and permeability in vivo.
Topics: Animals; Blood-Brain Barrier; Body Weight; Brain Edema; Brain Injuries, Traumatic; Chronic Traumatic | 2022 |
Persistent Blunting of Penumbral Leukocyte Mobilization by Beta Blockade Administered for Two Weeks After Traumatic Brain Injury.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries, Traumatic; Disease Models, Animal; Leukoc | 2022 |
Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Blood-Brain Barrier; Bra | 2018 |
Catecholaminergic polymorphic ventricular tachycardia: successful emergency treatment with intravenous propranolol.
Topics: Adrenergic beta-Antagonists; Brain Edema; Catecholamines; Child; Decerebrate State; Electrocardiogra | 2004 |
Delayed postoperative neurological deterioration from prolonged sodium nitroprusside administration. Case report.
Topics: Brain Edema; Cerebral Hemorrhage; Coma; Craniotomy; Cyanides; Ferricyanides; Hematoma; Humans; Hyper | 1989 |
[Study of the protective effect of propranolol in anoxic ischemia in rats].
Topics: Animals; Brain Edema; Female; Hypoxia, Brain; Ischemic Attack, Transient; Male; Propranolol; Rats; S | 1973 |