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propranolol and Bone Loss, Osteoclastic

propranolol has been researched along with Bone Loss, Osteoclastic in 15 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"Hydroxyproline excretion was increased by hyperthyroid patients."9.05[Effects of propranolol and indomethacin upon urinary hydroxyproline in hyperthyroid patients (author's transl)]. ( Benzoni, D; Beylot, M; Bodson, A; Mornex, R; Riou, JP; Vincent, M, 1982)
"Low doses of propranolol suppress bone resorption by inhibiting RANKL-mediated osteoclastogenesis as well as inflammatory markers without affecting haemodynamic parameters."5.38Low dose of propranolol down-modulates bone resorption by inhibiting inflammation and osteoclast differentiation. ( Barbosa-Neto, O; Clemente-Napimoga, JT; da Silva, TA; Dias-da-Silva, VJ; Lopes, AH; Madeira, MF; Miguel, CB; Napimoga, MH; Rodrigues, WF, 2012)
"The incidence of bone resorption evaluated on X-ray findings and on bone biopsy specimens was of a comparable degree in the two groups."5.26Effect of chronic propranolol treatment on bone changes of secondary hyperparathyroidism in dialysis patients. ( Ballanti, P; Bonucci, E; Ciccarelli, C; Maggiore, Q; Pizzarelli, F; Zoccali, C, 1982)
"Hydroxyproline excretion was increased by hyperthyroid patients."5.05[Effects of propranolol and indomethacin upon urinary hydroxyproline in hyperthyroid patients (author's transl)]. ( Benzoni, D; Beylot, M; Bodson, A; Mornex, R; Riou, JP; Vincent, M, 1982)
"Low doses of propranolol suppress bone resorption by inhibiting RANKL-mediated osteoclastogenesis as well as inflammatory markers without affecting haemodynamic parameters."1.38Low dose of propranolol down-modulates bone resorption by inhibiting inflammation and osteoclast differentiation. ( Barbosa-Neto, O; Clemente-Napimoga, JT; da Silva, TA; Dias-da-Silva, VJ; Lopes, AH; Madeira, MF; Miguel, CB; Napimoga, MH; Rodrigues, WF, 2012)
"Propranolol-treated animals drank significantly less water, but did not differ in daily chow consumption or body weight gain."1.37The effects of systemic chemical sympathectomy on local bone loss induced by sciatic neurectomy. ( Chen, HI; Huang, TH; Lin, HS; Yang, RS, 2011)
"placebo, P = 0."1.35Low dose beta-blocker prevents ovariectomy-induced bone loss in rats without affecting heart functions. ( Benhamou, CL; Bonnet, N; Courteix, D; Eder, V; Goncalves, C; Malaval, L; Pichon, C; Vico, L, 2008)
"The incidence of bone resorption evaluated on X-ray findings and on bone biopsy specimens was of a comparable degree in the two groups."1.26Effect of chronic propranolol treatment on bone changes of secondary hyperparathyroidism in dialysis patients. ( Ballanti, P; Bonucci, E; Ciccarelli, C; Maggiore, Q; Pizzarelli, F; Zoccali, C, 1982)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's6 (40.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Treyball, A1
Bergeron, AC1
Brooks, DJ1
Langlais, AL1
Hashmi, H1
Nagano, K1
Barlow, D1
Neilson, RJ1
Roy, TA1
Nevola, KT1
Houseknecht, KL1
Baron, R1
Bouxsein, ML1
Guntur, AR1
Motyl, KJ1
Uchibori, S1
Sekiya, T1
Sato, T2
Hayashi, K1
Takeguchi, A1
Muramatsu, R1
Ishizuka, K1
Kondo, H1
Miyazawa, K1
Togari, A2
Goto, S2
Baek, K2
Hwang, HR1
Park, HJ1
Kwon, A1
Qadir, AS1
Baek, JH1
Ortuño, MJ1
Robinson, ST1
Subramanyam, P1
Paone, R1
Huang, YY1
Guo, XE1
Colecraft, HM1
Mann, JJ1
Ducy, P1
Bonnet, N2
Benhamou, CL2
Malaval, L1
Goncalves, C1
Vico, L2
Eder, V1
Pichon, C1
Courteix, D2
Arai, M1
Huang, TH1
Lin, HS1
Chen, HI1
Yang, RS1
Rodrigues, WF1
Madeira, MF1
da Silva, TA1
Clemente-Napimoga, JT1
Miguel, CB1
Dias-da-Silva, VJ1
Barbosa-Neto, O1
Lopes, AH1
Napimoga, MH1
Bloomfield, SA1
sseur, R1
Sabatier, JP1
Potrel-Burgot, C1
Lecoq, B1
Creveuil, C1
Marcelli, C1
Laroche, N1
Dolleans, E1
Beylot, M1
Vincent, M1
Benzoni, D1
Bodson, A1
Riou, JP1
Mornex, R1
Pizzarelli, F1
Zoccali, C1
Ciccarelli, C1
Maggiore, Q1
Bonucci, E1
Ballanti, P1
Dietrich, JW1
Mundy, GR1
Raisz, LG1
Herrmann-Erlee, MP1

Trials

1 trial available for propranolol and Bone Loss, Osteoclastic

ArticleYear
[Effects of propranolol and indomethacin upon urinary hydroxyproline in hyperthyroid patients (author's transl)].
    La Nouvelle presse medicale, 1982, Mar-20, Volume: 11, Issue:13

    Topics: Adult; Aged; Bone Resorption; Calcium; Female; Humans; Hydroxyproline; Hyperthyroidism; Indomethacin

1982

Other Studies

14 other studies available for propranolol and Bone Loss, Osteoclastic

ArticleYear
Propranolol Promotes Bone Formation and Limits Resorption Through Novel Mechanisms During Anabolic Parathyroid Hormone Treatment in Female C57BL/6J Mice.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2022, Volume: 37, Issue:5

    Topics: Animals; Bone and Bones; Bone Resorption; Female; Humans; Mice; Mice, Inbred C57BL; Osteoblasts; Ost

2022
Suppression of tooth movement-induced sclerostin expression using β-adrenergic receptor blockers.
    Oral diseases, 2020, Volume: 26, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Bone Morphogenetic Proteins; Bone Remodeling; Bone R

2020
Propranolol, a β-adrenergic antagonist, attenuates the decrease in trabecular bone mass in high calorie diet fed growing mice.
    BMB reports, 2014, Volume: 47, Issue:9

    Topics: Adrenergic Antagonists; Animals; Body Weight; Bone Density; Bone Marrow Cells; Bone Resorption; Diet

2014
Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect.
    Nature medicine, 2016, Volume: 22, Issue:10

    Topics: Adrenergic beta-Antagonists; Animals; Bone and Bones; Bone Remodeling; Bone Resorption; Calcium; Flu

2016
Low dose beta-blocker prevents ovariectomy-induced bone loss in rats without affecting heart functions.
    Journal of cellular physiology, 2008, Volume: 217, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Biomechanical Phenomena; Blood Pressure; Bone Density; Bone Re

2008
Effects of propranolol on bone metabolism in spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 334, Issue:1

    Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Bone D

2010
The effects of systemic chemical sympathectomy on local bone loss induced by sciatic neurectomy.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2011, Volume: 16, Issue:5

    Topics: Activating Transcription Factor 4; Adrenergic beta-Antagonists; Animals; Bone and Bones; Bone Diseas

2011
Low dose of propranolol down-modulates bone resorption by inhibiting inflammation and osteoclast differentiation.
    British journal of pharmacology, 2012, Volume: 165, Issue:7

    Topics: Acid Phosphatase; Alveolar Bone Loss; Animals; Bone Resorption; Cathepsin K; Cell Differentiation; C

2012
Blocking β-adrenergic signaling attenuates reductions in circulating leptin, cancellous bone mass, and marrow adiposity seen with dietary energy restriction.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Dec-01, Volume: 113, Issue:11

    Topics: Adaptation, Physiological; Adipocytes; Adiposity; Adrenergic beta-Antagonists; Animals; Biomarkers;

2012
Sympathetic nervous system as transmitter of mechanical loading in bone.
    Joint bone spine, 2003, Volume: 70, Issue:6

    Topics: Absorptiometry, Photon; Adrenergic beta-Antagonists; Animals; Biomechanical Phenomena; Bone and Bone

2003
Dose effects of propranolol on cancellous and cortical bone in ovariectomized adult rats.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:3

    Topics: Animals; Bone and Bones; Bone Density; Bone Resorption; Dose-Response Relationship, Drug; Female; Fe

2006
Effect of chronic propranolol treatment on bone changes of secondary hyperparathyroidism in dialysis patients.
    Nephron, 1982, Volume: 32, Issue:1

    Topics: Bone Resorption; Chronic Kidney Disease-Mineral and Bone Disorder; Humans; Hyperparathyroidism, Seco

1982
Inhibition of bone resorption in tissue culture by membrane-stabilizing drugs.
    Endocrinology, 1979, Volume: 104, Issue:6

    Topics: Animals; Bone and Bones; Bone Resorption; Calcium; DNA; Fetus; Kinetics; Lidocaine; Parathyroid Horm

1979
The effects of dibutyryl cyclic AMP, aminophylline and propranolol on PTE-induced bone resorption in vitro.
    Endocrinology, 1974, Volume: 94, Issue:2

    Topics: Aminophylline; Animals; Bone and Bones; Bone Resorption; Bucladesine; Calcium; Dose-Response Relatio

1974