Page last updated: 2024-11-03

propranolol and Bilharziasis

propranolol has been researched along with Bilharziasis in 13 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"To compare the effects of propranolol (PR) to that of PR plus isosorbide-5-mononitrate (ISMN) on variceal pressure in patients with schistosomiasis."9.17Effects of propranolol or propranolol plus isosorbide-5-mononitrate on variceal pressure in schistosomiasis. ( Chen, C; Hao, JH; Kong, DR; Li, P; Ma, C; Wang, JG; Wang, M; Xu, JM; Zhang, L, 2013)
" Forty consecutive patients with bleeding oesophageal varices underwent either injection sclerotherapy only or injection sclerotherapy with an adjuvant fixed daily dose of propranolol (40 mg tds) in a single-blind randomized controlled trial."9.11Endoscopic sclerotherapy of oesophageal varices due to hepatosplenic schistosomiasis. A randomized controlled trial evaluating the effect of adjuvant propranolol therapy. ( Abdel Baki, M; Dowidar, N; Hafez, A, 2005)
" In the present, double-blind, 24-month, prospective study of patients with endoscopically-proven varices and ultrasonographically-confirmed hepatic fibrosis, the effects of propranolol 160 mg LA and placebo on the incidence of rebleeding and mortality were compared in 82 patients with portal hypertension secondary to schistosomiasis."9.07Propranolol reduces mortality in patients with portal hypertension secondary to schistosomiasis. ( el Amin, AA; el Tourabi, H; Harron, DW; Homeida, M; Shaheen, M; Woda, SA, 1994)
"Eight Sudanese patients with hepatosplenic schistosomiasis and seven Sudanese controls were administered a single oral dose of long acting (LA), propranolol 160 mg; blood propranolol levels were measured at regular intervals for 12 h using g."7.67Propranolol disposition in patients with hepatosplenic schistosomiasis. ( Ali, HM; Arbab, BM; Harron, DW; Homeida, MM, 1987)
"Propranolol is a non-selective beta-blocker used as secondary prophylaxis for UVB, but no previous studies have addressed carvedilol effects in rebleeding prevention."5.72Carvedilol as secondary prophylaxis for variceal bleeding in hepatosplenic schistosomiasis. ( Cançado, GGL; Cardoso, JB; Couto, CA; de Abreu, ES; Faria, LC; Ferrari, TCA; Lima, AMC; Nardelli, MJ; Osório, FMF, 2022)
"To compare the effects of propranolol (PR) to that of PR plus isosorbide-5-mononitrate (ISMN) on variceal pressure in patients with schistosomiasis."5.17Effects of propranolol or propranolol plus isosorbide-5-mononitrate on variceal pressure in schistosomiasis. ( Chen, C; Hao, JH; Kong, DR; Li, P; Ma, C; Wang, JG; Wang, M; Xu, JM; Zhang, L, 2013)
" Forty consecutive patients with bleeding oesophageal varices underwent either injection sclerotherapy only or injection sclerotherapy with an adjuvant fixed daily dose of propranolol (40 mg tds) in a single-blind randomized controlled trial."5.11Endoscopic sclerotherapy of oesophageal varices due to hepatosplenic schistosomiasis. A randomized controlled trial evaluating the effect of adjuvant propranolol therapy. ( Abdel Baki, M; Dowidar, N; Hafez, A, 2005)
" In the present, double-blind, 24-month, prospective study of patients with endoscopically-proven varices and ultrasonographically-confirmed hepatic fibrosis, the effects of propranolol 160 mg LA and placebo on the incidence of rebleeding and mortality were compared in 82 patients with portal hypertension secondary to schistosomiasis."5.07Propranolol reduces mortality in patients with portal hypertension secondary to schistosomiasis. ( el Amin, AA; el Tourabi, H; Harron, DW; Homeida, M; Shaheen, M; Woda, SA, 1994)
"This study evaluates systemic and splanchnic haemodynamics and the effect of propranolol in 15 patients with presinusoidal portal hypertension (portal vein obstruction, n = 11; schistosomiasis, n = 4)."3.67Hyperkinetic circulatory syndrome in patients with presinusoidal portal hypertension. Effect of propranolol. ( Braillon, A; Hadengue, A; Lebrec, D; Moreau, R; Roulot, D; Sayegh, R, 1989)
"Eight Sudanese patients with hepatosplenic schistosomiasis and seven Sudanese controls were administered a single oral dose of long acting (LA), propranolol 160 mg; blood propranolol levels were measured at regular intervals for 12 h using g."3.67Propranolol disposition in patients with hepatosplenic schistosomiasis. ( Ali, HM; Arbab, BM; Harron, DW; Homeida, MM, 1987)
"Propranolol is a non-selective beta-blocker used as secondary prophylaxis for UVB, but no previous studies have addressed carvedilol effects in rebleeding prevention."1.72Carvedilol as secondary prophylaxis for variceal bleeding in hepatosplenic schistosomiasis. ( Cançado, GGL; Cardoso, JB; Couto, CA; de Abreu, ES; Faria, LC; Ferrari, TCA; Lima, AMC; Nardelli, MJ; Osório, FMF, 2022)
"Schistosomiasis is a chronic parasitic disease affecting hundreds of millions of individuals worldwide."1.35Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis. ( Arnér, ES; Austin, CP; Chakrapani, H; Inglese, J; Jadhav, A; Keefer, L; Lea, WA; Leister, W; Luecke, HF; Maloney, DJ; Prast-Nielsen, S; Rai, G; Sayed, AA; Shen, M; Simeonov, A; Thomas, CJ; Williams, DL, 2009)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's3 (23.08)18.2507
2000's3 (23.08)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Rai, G1
Sayed, AA1
Lea, WA1
Luecke, HF1
Chakrapani, H1
Prast-Nielsen, S1
Jadhav, A1
Leister, W1
Shen, M1
Inglese, J1
Austin, CP1
Keefer, L1
Arnér, ES1
Simeonov, A1
Maloney, DJ1
Williams, DL1
Thomas, CJ1
de Abreu, ES1
Nardelli, MJ1
Lima, AMC1
Cardoso, JB1
Osório, FMF1
Ferrari, TCA1
Faria, LC1
Couto, CA1
Cançado, GGL1
Kong, DR1
Ma, C1
Wang, M1
Wang, JG1
Chen, C1
Zhang, L1
Hao, JH1
Li, P1
Xu, JM1
Juraschek, SP1
Bankova, L1
Falade, O1
Chow, G1
McKenzie, R1
Bhogal, HK1
Dowidar, N1
Hafez, A1
Abdel Baki, M1
el Tourabi, H1
el Amin, AA1
Shaheen, M1
Woda, SA1
Homeida, M1
Harron, DW2
Ferraz, AA1
Wanderley, GJ1
Santos, MA1
Mathias, CA1
Araújo, JG1
Ferraz, EM1
Fayez, MA1
Aziz, S1
el-Gengehy, MT1
Othman, A1
Blendis, LM1
Conn, HO1
Braillon, A1
Moreau, R1
Hadengue, A1
Roulot, D1
Sayegh, R1
Lebrec, D1
el-Hawy, A1
el Nasr, MS1
Hussein, T1
el-Sayed, AA1
Homeida, MM1
Ali, HM1
Arbab, BM1

Trials

4 trials available for propranolol and Bilharziasis

ArticleYear
Effects of propranolol or propranolol plus isosorbide-5-mononitrate on variceal pressure in schistosomiasis.
    World journal of gastroenterology, 2013, Jul-14, Volume: 19, Issue:26

    Topics: Adult; China; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Gastrointestinal He

2013
Endoscopic sclerotherapy of oesophageal varices due to hepatosplenic schistosomiasis. A randomized controlled trial evaluating the effect of adjuvant propranolol therapy.
    Journal of the Egyptian Society of Parasitology, 2005, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Chemotherapy, Adjuvant; Esophageal and Gastric Varices; Female; Humans; Mal

2005
Propranolol reduces mortality in patients with portal hypertension secondary to schistosomiasis.
    Annals of tropical medicine and parasitology, 1994, Volume: 88, Issue:5

    Topics: Adult; Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hum

1994
Effects of propranolol on human postoperative ileus.
    Digestive surgery, 2001, Volume: 18, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Colon; Electromyography; Female; Gastrointestinal Motility

2001

Other Studies

9 other studies available for propranolol and Bilharziasis

ArticleYear
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Biological Availability; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentratio

2009
Carvedilol as secondary prophylaxis for variceal bleeding in hepatosplenic schistosomiasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2022, 07-06, Volume: 116, Issue:7

    Topics: Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Ligation; Propranol

2022
An uncommon cause of portal hypertension: schistosomiasis.
    The American journal of medicine, 2011, Volume: 124, Issue:2

    Topics: Adult; Animals; Anthelmintics; Antihypertensive Agents; Hepatomegaly; Humans; Hypertension, Portal;

2011
Effect of B-blockers on the hepatic blood flow in bilharzial hepatosplenomegaly.
    The Journal of the Egyptian Medical Association, 1975, Volume: 58, Issue:1-2

    Topics: Adolescent; Adult; Female; Hepatomegaly; Humans; Liver Circulation; Male; Propranolol; Schistosomias

1975
The influence of propanolol on portosystemic shunting.
    Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:5

    Topics: Animals; Blood Circulation; Hypertension, Portal; Mice; Mice, Inbred C3H; Portal System; Propranolol

1991
Propranolol-induced reduction in recurrent variceal hemorrhage in schistosomiasis.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:6

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Propranolol; Recurrence; Schist

1990
Hyperkinetic circulatory syndrome in patients with presinusoidal portal hypertension. Effect of propranolol.
    Journal of hepatology, 1989, Volume: 9, Issue:3

    Topics: Adult; Collateral Circulation; Female; Gastrointestinal Hemorrhage; Heart Rate; Hemodynamics; Hepati

1989
Comparative study between propranolol and sclerotherapy in prophylactic treatment of oesophageal varices and prevention of recurrent bleeding attacks.
    Journal of the Egyptian Society of Parasitology, 1987, Volume: 17, Issue:2

    Topics: Adult; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Propr

1987
Propranolol disposition in patients with hepatosplenic schistosomiasis.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Female; Humans; Liver Diseases, Parasitic; Male; Middle Aged; Propranolol; Schist

1987