propranolol has been researched along with Bacterial Disease in 12 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been suggested that propranolol may have a protective effect on the development of spontaneous bacterial peritonitis by increasing the motility of the bowel and lowering the pressure of the portal vein." | 7.73 | Spontaneous bacterial peritonitis in cirrhotic patients: Is prophylactic propranolol therapy beneficial? ( Archimandritis, AJ; Burroughs, AK; Cholongitas, E; Manesis, EK; Papatheodoridis, GV, 2006) |
| " The beta-blocker propranolol, known for its effectiveness on cutaneous hemangiomas, is also proving useful for the treatment of subglottic or visceral hemangiomas." | 3.78 | [Pediatrics]. ( Chevallay, M; de Buys Roessingh, A; El Ezzi, O; Fischer, CJ; Gehri, M; Giannoni, E; Hauschild, M; Hohlfeld, J; Pauchard, JY; Seneggen, E; Tolsa, JF; Truttmann, AC, 2012) |
| "It has been suggested that propranolol may have a protective effect on the development of spontaneous bacterial peritonitis by increasing the motility of the bowel and lowering the pressure of the portal vein." | 3.73 | Spontaneous bacterial peritonitis in cirrhotic patients: Is prophylactic propranolol therapy beneficial? ( Archimandritis, AJ; Burroughs, AK; Cholongitas, E; Manesis, EK; Papatheodoridis, GV, 2006) |
| "Bacterial infections have been hypothetized to be a trigger of variceal bleeding in cirrhotic patients and beta-blockers may have a protective effect by decreasing bacterial translocation, reducing portal pressure." | 2.45 | beta-Blockers protect against spontaneous bacterial peritonitis in cirrhotic patients: a meta-analysis. ( Burra, P; Burroughs, AK; Cholongitas, E; Leandro, G; Patch, D; Senzolo, M; Thalheimer, U, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Senzolo, M | 2 |
| Cholongitas, E | 3 |
| Burra, P | 1 |
| Leandro, G | 1 |
| Thalheimer, U | 2 |
| Patch, D | 2 |
| Burroughs, AK | 3 |
| Angeli, P | 1 |
| Wong, CH | 1 |
| Jenne, CN | 1 |
| Lee, WY | 1 |
| Léger, C | 1 |
| Kubes, P | 1 |
| Fischer, CJ | 1 |
| Giannoni, E | 1 |
| Truttmann, AC | 1 |
| Tolsa, JF | 1 |
| Chevallay, M | 1 |
| El Ezzi, O | 1 |
| Seneggen, E | 1 |
| Hohlfeld, J | 1 |
| de Buys Roessingh, A | 1 |
| Pauchard, JY | 1 |
| Gehri, M | 1 |
| Hauschild, M | 1 |
| Abraldes, JG | 1 |
| Tarantino, I | 1 |
| Turnes, J | 1 |
| Garcia-Pagan, JC | 1 |
| Rodés, J | 1 |
| Bosch, J | 1 |
| Prass, K | 1 |
| Meisel, C | 1 |
| Höflich, C | 1 |
| Braun, J | 1 |
| Halle, E | 1 |
| Wolf, T | 1 |
| Ruscher, K | 1 |
| Victorov, IV | 1 |
| Priller, J | 1 |
| Dirnagl, U | 1 |
| Volk, HD | 1 |
| Meisel, A | 1 |
| Papatheodoridis, GV | 1 |
| Manesis, EK | 1 |
| Archimandritis, AJ | 1 |
| Marelli, L | 1 |
| Men'shikov, DD | 1 |
| Vasina, TA | 1 |
| Volenko, AV | 1 |
| Zalogueva, GV | 1 |
| Vasil'ev, VA | 1 |
| Babb, J | 1 |
| Bishop, H | 1 |
| Schneider, RE | 1 |
| Hawkins, CF | 1 |
| Hoare, AM | 1 |
| Kandel, G | 1 |
| Diamant, NE | 1 |
| Chachaj, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Type I Hepatorenal Syndrome (HRS) With Pentoxyfylline: A Placebo Controlled, Blinded Pilot Study[NCT02123576] | 12 participants (Actual) | Interventional | 2014-04-30 | Terminated (stopped due to Poor enrollment of study population) | |||
| Pilot Study to Evaluate the Correlation Between ¹³C Methacetin Breath Test (MBT) and HVPG Measurement as a Tool for Identifying Responders to Portal Hypertension Therapy[NCT01851252] | Phase 1 | 19 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| Role of Th1-lymphocytes in the Development of Vascular Cognitive Impairment in Young Stroke Patients[NCT03725137] | 77 participants (Anticipated) | Observational | 2020-01-31 | Not yet recruiting | |||
| Predictors of Early Chest Infection in Acute Ischemic Stroke[NCT00906542] | 530 participants (Actual) | Observational | 2009-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT02123576)
Timeframe: baseline and 14 days
| Intervention | g/dL (Mean) |
|---|---|
| Treatment | 0.48 |
| Placebo | 0.03 |
Defined as creatinine level above baseline value after day 7, dialysis or death (NCT02123576)
Timeframe: up to day 14
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment | 3 |
| Placebo | 3 |
We define as serum creatinine level decreased by >50% from baseline but not to <1.5 mg/dL, without dialysis or HRS recurrence (NCT02123576)
Timeframe: 14 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment | 1 |
| Placebo | 2 |
We define this as a decrease in serum creatinine level to <1.5 mg/dL without dialysis or death (NCT02123576)
Timeframe: 14 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment | 1 |
| Placebo | 1 |
This will be the combination of transplant free survival and those patients who received liver transplant (NCT02123576)
Timeframe: up to 1 year
| Intervention | days (Mean) |
|---|---|
| Treatment | 102 |
| Placebo | 59 |
(NCT02123576)
Timeframe: day 30 and 180
| Intervention | days (Mean) |
|---|---|
| Treatment | 80 |
| Placebo | 36 |
3 reviews available for propranolol and Bacterial Disease
| Article | Year |
|---|---|
beta-Blockers protect against spontaneous bacterial peritonitis in cirrhotic patients: a meta-analysis.
Topics: Adrenergic beta-Antagonists; Bacterial Infections; Bacterial Translocation; Databases, Bibliographic | 2009 |
A clinical view of recent advances in ascites.
Topics: Animals; Ascites; Ascitic Fluid; Bacterial Infections; Blood Volume; Body Water; Extracellular Space | 1986 |
[Clinical forms and physiopathology of bronchial asthma in the light of present-day views].
Topics: Age Factors; Asthma; Bacterial Infections; Bronchi; Chronic Disease; Histamine; Humans; Immunoglobul | 1971 |
9 other studies available for propranolol and Bacterial Disease
| Article | Year |
|---|---|
β-blockers and refractory ascites in cirrhosis: the message of a team of true scientists.
Topics: Adrenergic beta-Antagonists; Ascites; Bacterial Infections; Cardiovascular Diseases; Female; Hepator | 2011 |
Functional innervation of hepatic iNKT cells is immunosuppressive following stroke.
Topics: Adrenergic Agents; Animals; Anti-Bacterial Agents; Bacterial Infections; Brain Ischemia; Cell Moveme | 2011 |
[Pediatrics].
Topics: Adrenergic beta-Agonists; Bacterial Infections; Breast Feeding; Enterocolitis, Necrotizing; Fever; G | 2012 |
Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis.
Topics: Antihypertensive Agents; Ascites; Bacterial Infections; Cohort Studies; Drug Therapy, Combination; F | 2003 |
Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation.
Topics: Animals; Bacteremia; Bacterial Infections; Disease Models, Animal; Female; Humans; Immunization; Imm | 2003 |
Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation.
Topics: Animals; Bacteremia; Bacterial Infections; Disease Models, Animal; Female; Humans; Immunization; Imm | 2003 |
Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation.
Topics: Animals; Bacteremia; Bacterial Infections; Disease Models, Animal; Female; Humans; Immunization; Imm | 2003 |
Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation.
Topics: Animals; Bacteremia; Bacterial Infections; Disease Models, Animal; Female; Humans; Immunization; Imm | 2003 |
Spontaneous bacterial peritonitis in cirrhotic patients: Is prophylactic propranolol therapy beneficial?
Topics: Adrenergic beta-Antagonists; Aged; Ascites; Ascitic Fluid; Bacterial Infections; Chi-Square Distribu | 2006 |
The low incidence of bacterial infections could be a protective factor against variceal bleeding per se in hemodynamic responders to propranolol.
Topics: Antihypertensive Agents; Bacterial Infections; Esophageal and Gastric Varices; Gastrointestinal Hemo | 2006 |
[Effect of drugs of various groups on the course of experimental local pyo-inflammatory processes].
Topics: Adrenergic Agents; Adrenergic beta-Antagonists; Animals; Anti-Bacterial Agents; Anticoagulants; Bact | 1995 |
Letter: Plasma-propranolol levels in inflammation disease.
Topics: Bacterial Infections; Blood Sedimentation; Humans; Inflammation; Propranolol | 1976 |