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propranolol and Autoimmune Diabetes

propranolol has been researched along with Autoimmune Diabetes in 37 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"The insulin resistance is due to beta-adrenergic stimulation and can be prevented by propranolol."2.66Insulin resistance in type 1 (insulin-dependent) diabetes following hypoglycaemia--evidence for the importance of beta-adrenergic stimulation. ( Attvall, S; Fowelin, J; Lager, I; Smith, U; von Schenck, H, 1987)
"Of 15 patients with clinical diabetic autonomic neuropathy, SPR wave forms were bizarre or absent in 5 patients compared with 18 of 121 patients' without clinical autonomic neuropathy (chi 2 = 3."1.28Validation and evaluation of test for sympathetic cholinergic function in diabetes mellitus. ( Best, JD; Kirsner, RL; Pestell, RG, 1991)
"Diabetic nephropathy is the dominant cause of hypertension in insulin-dependent diabetics, and long-term rigid antihypertensive treatment inhibits the progression of nephropathy, probably even when there is renal insufficiency."1.28The effect of antihypertensive treatment on kidney function in insulin-dependent (type I) diabetics with renal failure. ( Conde, N; Gums, G; Heinke, P; Schulz, B; Strese, J; Zander, E; Zander, G, 1990)
"However, in IDDM with blunted plasma glucagon responses, postnadir plasma glucose recovery was further decreased by propranolol (14 +/- 0."1.27The adrenergic contribution to glucose counterregulation in type I diabetes mellitus. Dependency on A-cell function and mediation through beta 2-adrenergic receptors. ( Angeletti, G; Bolli, G; Brunetti, P; Compagnucci, P; De Cosmo, S; De Feo, P; Gerich, JE; Motolese, M; Perriello, G; Santeusanio, F, 1983)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199023 (62.16)18.7374
1990's10 (27.03)18.2507
2000's2 (5.41)29.6817
2010's1 (2.70)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Cui, P1
Macdonald, TL1
Chen, M1
Nadler, JL1
Cardinez, N1
Bakhsh, A1
Perkins, BA1
Kose, S1
Gozaydin, A1
Akkoclu, G1
Ece, G1
Lager, I2
Ostman, J1
De Feo, P1
Bolli, G1
Perriello, G1
De Cosmo, S1
Compagnucci, P1
Angeletti, G1
Santeusanio, F1
Gerich, JE3
Motolese, M1
Brunetti, P1
Simonson, DC2
Koivisto, V1
Sherwin, RS2
Ferrannini, E1
Hendler, R1
Juhlin-Dannfelt, A1
DeFronzo, RA2
Gray, RS1
Borsey, DQ1
Irvine, WJ1
Duncan, LJ1
Clarke, BF1
Shamoon, H2
Sherwin, R1
Jacob, R1
Marfella, R1
Giugliano, D1
di Maro, G1
Acampora, R1
Giunta, R1
D'Onofrio, F1
Bolinder, J1
Sjöberg, S1
Arner, P1
Cooper, JW1
Chalon, S1
Berlin, I1
Sachon, C1
Bosquet, F2
Grimaldi, A2
Sigal, RJ1
Fisher, SJ1
Halter, JB2
Vranic, M1
Marliss, EB1
Gallego, M1
Casis, E1
Izquierdo, MJ1
Casis, O1
Saiki, S1
Lorenzi, M1
Tsalikian, E1
Karam, JH1
Sperling, MA1
Voina, S1
Benn, JJ1
Brown, PM1
Beckwith, LJ1
Farebrother, M1
Sönksen, PH1
Hirsch, IB1
Boyle, PJ1
Craft, S1
Cryer, PE2
Pestell, RG1
Kirsner, RL1
Best, JD1
Diem, P1
Redmon, JB1
Abid, M1
Moran, A1
Sutherland, DE1
Robertson, RP1
Zander, E1
Conde, N1
Heinke, P1
Zander, G1
Strese, J1
Gums, G1
Schulz, B1
Succi, E1
Albanesi Filho, FM1
Gomes, MB1
Gomes Filho, JB1
Attvall, S1
Fowelin, J1
von Schenck, H1
Smith, U1
Krone, W1
Naegele, H1
Behnke, B1
Greten, H1
Campbell, PJ1
Bolli, GB1
McClure, AD1
Beylot, M1
Sautot, G1
Dechaud, H1
Cohen, R1
Riou, JP1
Serusclat, P1
Mornex, R1
Castellino, P1
Kotler, MN1
Berman, L1
Rubenstein, AH1
Hansen, AP1
Loggie, JM1
Van Maanen, EF1
Lundbaek, K1
Avruskin, TW1
Tang, SC1
Juan, CS1

Reviews

3 reviews available for propranolol and Autoimmune Diabetes

ArticleYear
beta-adrenergic blockade and diabetes mellitus. A review.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 672

    Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; D

1983
[Blood glucose counter-regulation].
    Annales de medecine interne, 1985, Volume: 136, Issue:2

    Topics: Adrenergic beta-Antagonists; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids; Glu

1985
The autonomic nervous system and some aspects of the use of autonomic drugs in children. II.
    The Journal of pediatrics, 1972, Volume: 81, Issue:3

    Topics: Adrenergic beta-Antagonists; Aortic Valve Stenosis; Asthma; Autonomic Agents; Bronchitis; Cardiomyop

1972

Trials

3 trials available for propranolol and Autoimmune Diabetes

ArticleYear
Propranolol in hypoglycaemia unawareness.
    Diabetes & metabolism, 1999, Volume: 25, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Humans;

1999
Insulin resistance in type 1 (insulin-dependent) diabetes following hypoglycaemia--evidence for the importance of beta-adrenergic stimulation.
    Diabetologia, 1987, Volume: 30, Issue:9

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Heart Rate; Humans; Hyperglycemia; Hypoglyc

1987
The effect of adrenergic receptor blockade on the exercise-induced serum growth hormone rise in normals and juvenile diabetics.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 33, Issue:5

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Glucose; Clinica

1971

Other Studies

31 other studies available for propranolol and Autoimmune Diabetes

ArticleYear
Synthesis and biological evaluation of lisofylline (LSF) analogs as a potential treatment for Type 1 diabetes.
    Bioorganic & medicinal chemistry letters, 2006, Jul-01, Volume: 16, Issue:13

    Topics: Animals; Apoptosis; Cell Line; Chemoprevention; Cytokines; Diabetes Mellitus, Type 1; Drug Evaluatio

2006
Propranolol-induced Pancreatitis After Treatment for Graves' Disease in an Adult With Type 1 Diabetes.
    Canadian journal of diabetes, 2023, Volume: 47, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 1; Graves Disease; Humans; Pancreatitis; Propranolol

2023
Chronic hepatitis B with type I diabetes mellitus and autoimmune thyroiditis development during interferon alpha therapy.
    Journal of infection in developing countries, 2012, Apr-13, Volume: 6, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Antiviral Agents; Diabetes Mellitus, Type 1; Hepatitis B, Chroni

2012
Adrenergic blockade and hypoglycaemia.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 672

    Topics: Adrenergic beta-Antagonists; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Glucag

1983
The adrenergic contribution to glucose counterregulation in type I diabetes mellitus. Dependency on A-cell function and mediation through beta 2-adrenergic receptors.
    Diabetes, 1983, Volume: 32, Issue:10

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Hemodynamics; Humans; Insulin; Metoprol

1983
Adrenergic blockade alters glucose kinetics during exercise in insulin-dependent diabetics.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:6

    Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; I

1984
Non-insulin-treated ICA positive and negative diabetics are equally insulin resistant.
    Diabete & metabolisme, 1983, Volume: 9, Issue:4

    Topics: Adult; Antibodies; Autoantibodies; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type

1983
Beta-adrenergic blockade is more effective in suppressing adrenaline-induced glucose production in Type 1 (insulin-dependent) diabetes.
    Diabetologia, 1984, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucose; Humans; I

1984
Epinephrine-induced hypoaminoacidemia in normal and diabetic human subjects: effect of beta blockade.
    Diabetes, 1980, Volume: 29, Issue:11

    Topics: Adult; Amino Acids; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans;

1980
The squatting test. A useful tool to assess both parasympathetic and sympathetic involvement of the cardiovascular autonomic neuropathy in diabetes.
    Diabetes, 1994, Volume: 43, Issue:4

    Topics: Adult; Age Factors; Aged; Atropine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic N

1994
Stimulation of adipose tissue lipolysis following insulin-induced hypoglycaemia: evidence of increased beta-adrenoceptor-mediated lipolytic response in IDDM.
    Diabetologia, 1996, Volume: 39, Issue:7

    Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Analysis of Varian

1996
Fatal asymptomatic hypoglycemia in an elderly insulin-dependent diabetic patient taking an oral beta-blocking medication.
    Diabetes care, 1998, Volume: 21, Issue:12

    Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Diabetes Mellitus, Type 1; Diabetic Angiopathies

1998
Glucoregulation during and after intense exercise: effects of beta-adrenergic blockade in subjects with type 1 diabetes mellitus.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:11

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrin

1999
Restoration of cardiac transient outward potassium current by norepinephrine in diabetic rats.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 441, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Nervous System Disease

2000
Preclinical abnormality of cardiac function in juvenile-onset type diabetics: the effects of autonomic nervous blocking and dynamic exercise on cardiac function.
    Japanese circulation journal, 1978, Volume: 42, Issue:12

    Topics: Adolescent; Adult; Atropine; Autonomic Nervous System; Diabetes Mellitus, Type 1; Echocardiography;

1978
Studies on the mechanism of epinephrine-induced hyperglycemia in man. Evidence for participation of pancreatic glucagon secretion.
    Diabetes, 1976, Volume: 25, Issue:1

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Synergism; Epinephrine; Fatty Acids, Nonesteri

1976
Effect of adrenergic blockade on glucagon and growth hormone secretion in normal and diabetic children.
    Pediatric research, 1975, Volume: 9, Issue:9

    Topics: Adolescent; Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Horm

1975
Glucose turnover in type I diabetic subjects during exercise. Effect of selective and nonselective beta-blockade and insulin withdrawal.
    Diabetes care, 1992, Volume: 15, Issue:11

    Topics: Adult; Atenolol; Betaxolol; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Glucose; Glycated He

1992
Higher glycemic thresholds for symptoms during beta-adrenergic blockade in IDDM.
    Diabetes, 1991, Volume: 40, Issue:9

    Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glucose Clam

1991
Validation and evaluation of test for sympathetic cholinergic function in diabetes mellitus.
    Diabetes, 1991, Volume: 40, Issue:7

    Topics: Adult; Age Factors; Aged; Atropine; Autonomic Nervous System; Diabetes Mellitus; Diabetes Mellitus,

1991
Glucagon, catecholamine and pancreatic polypeptide secretion in type I diabetic recipients of pancreas allografts.
    The Journal of clinical investigation, 1990, Volume: 86, Issue:6

    Topics: Arginine; Catecholamines; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Humans; Hypog

1990
The effect of antihypertensive treatment on kidney function in insulin-dependent (type I) diabetics with renal failure.
    Experimental and clinical endocrinology, 1990, Volume: 95, Issue:1

    Topics: Acute Kidney Injury; Antihypertensive Agents; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1;

1990
[Diabetic cardiac dysautonomia. Clinical and pharmacologic evaluation].
    Arquivos brasileiros de cardiologia, 1989, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Atropine; Autonomic Nervous System Diseases; Blood Pressure; Child; Diabetes Mell

1989
Opposite effects of insulin and catecholamines on LDL-receptor activity in human mononuclear leukocytes.
    Diabetes, 1988, Volume: 37, Issue:10

    Topics: Catecholamines; Diabetes Mellitus, Type 1; Epinephrine; Humans; In Vitro Techniques; Insulin; Isopro

1988
Pathogenesis of the dawn phenomenon in patients with insulin-dependent diabetes mellitus. Accelerated glucose production and impaired glucose utilization due to nocturnal surges in growth hormone secretion.
    The New England journal of medicine, 1985, Jun-06, Volume: 312, Issue:23

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hype

1985
Mrs. McGiver's collapse--unmasking the true cause.
    Nursing, 1989, Volume: 19, Issue:3

    Topics: Aged; Diabetes Mellitus, Type 1; Female; Humans; Hypertension; Hypoglycemia; Propranolol; Syncope

1989
Lack of beta-adrenergic role for catecholamines in the development of hyperglycemia and ketonaemia following acute insulin withdrawal in type I diabetic patients.
    Diabete & metabolisme, 1985, Volume: 11, Issue:2

    Topics: Adult; Catecholamines; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Glucagon;

1985
Adrenergic modulation of potassium metabolism during exercise in normal and diabetic humans.
    The American journal of physiology, 1987, Volume: 252, Issue:1 Pt 1

    Topics: Adult; Bicarbonates; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Insulin; Kine

1987
Hypoglycaemia precipitated by propranolol.
    Lancet (London, England), 1966, Dec-24, Volume: 2, Issue:7478

    Topics: Adult; Aged; Diabetes Mellitus, Type 1; Female; Gastrectomy; Humans; Hypoglycemia; Insulin; Male; Pr

1966
Growth hormoe and diabetic angiopathy.
    Advances in metabolic disorders, 1973, Volume: 2

    Topics: Adolescent; Blood Glucose; Capillary Permeability; Child; Diabetes Mellitus; Diabetes Mellitus, Type

1973
Glucagon mediation of growth hormone secretion in juvenile diabetes mellitus.
    The American journal of the medical sciences, 1974, Volume: 267, Issue:6

    Topics: Adolescent; Blood Glucose; Body Weight; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Growth H

1974