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propranolol and Autistic Disorder

propranolol has been researched along with Autistic Disorder in 5 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)

Research Excerpts

ExcerptRelevanceReference
"A sample of 14 high-functioning adolescent and adult participants with autism and 14 matched controls were given letter and category word fluency tasks on 2 separate testing sessions; 1 test was given 60 minutes after the administration of 40 mg propranolol orally, and 1 test was given after placebo, administered in a double-blinded, counterbalanced manner."9.15Effect of propranolol on word fluency in autism. ( Beversdorf, DQ; Bodner, KE; Christ, SE; Higgins, KF; Kanne, SM; Saklayen, S, 2011)
"To report a case of an adolescent with autism with clinically significant hypersexual behaviors in whom a trial of low-dose propranolol led to major clinical improvement."7.80Use of propranolol for hypersexual behavior in an adolescent with autism. ( Agrawal, M, 2014)
"A sample of 14 high-functioning adolescent and adult participants with autism and 14 matched controls were given letter and category word fluency tasks on 2 separate testing sessions; 1 test was given 60 minutes after the administration of 40 mg propranolol orally, and 1 test was given after placebo, administered in a double-blinded, counterbalanced manner."5.15Effect of propranolol on word fluency in autism. ( Beversdorf, DQ; Bodner, KE; Christ, SE; Higgins, KF; Kanne, SM; Saklayen, S, 2011)
"To report a case of an adolescent with autism with clinically significant hypersexual behaviors in whom a trial of low-dose propranolol led to major clinical improvement."3.80Use of propranolol for hypersexual behavior in an adolescent with autism. ( Agrawal, M, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agrawal, M1
Beversdorf, DQ2
Carpenter, AL1
Miller, RF1
Cios, JS1
Hillier, A1
Saklayen, S1
Higgins, KF1
Bodner, KE1
Kanne, SM1
Christ, SE1
Gualtieri, CT1
Golden, RN1
Fahs, JJ1
Ratey, JJ1
Bemporad, J1
Sorgi, P1
Bick, P1
Polakoff, S1
O'Driscoll, G1
Mikkelsen, E1

Reviews

1 review available for propranolol and Autistic Disorder

ArticleYear
New developments in pediatric psychopharmacology.
    Journal of developmental and behavioral pediatrics : JDBP, 1983, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Aggression; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Autistic Disorder

1983

Trials

3 trials available for propranolol and Autistic Disorder

ArticleYear
Effect of propranolol on verbal problem solving in autism spectrum disorder.
    Neurocase, 2008, Volume: 14, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Asperger Syndrome; Autistic Disorder; Behavior; Child, Preschool

2008
Effect of propranolol on word fluency in autism.
    Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 2011, Volume: 24, Issue:1

    Topics: Adolescent; Adrenergic beta-Antagonists; Autistic Disorder; Female; Humans; Language Disorders; Male

2011
New developments in pediatric psychopharmacology.
    Journal of developmental and behavioral pediatrics : JDBP, 1983, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Aggression; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Autistic Disorder

1983

Other Studies

2 other studies available for propranolol and Autistic Disorder

ArticleYear
Use of propranolol for hypersexual behavior in an adolescent with autism.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:10

    Topics: Adolescent; Adrenergic beta-Antagonists; Autistic Disorder; Humans; Male; Propranolol; Sexual Behavi

2014
Open trial effects of beta-blockers on speech and social behaviors in 8 autistic adults.
    Journal of autism and developmental disorders, 1987, Volume: 17, Issue:3

    Topics: Adult; Autistic Disorder; Humans; Male; Propranolol; Social Behavior; Speech

1987