propranolol has been researched along with Autism Spectrum Disorder in 4 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The beta-adrenergic antagonist propranolol benefits some social and communication domains affected in autism spectrum disorder (ASD), and these benefits appear to be associated with increased functional connectivity (FC) in the brain during task performance." | 3.85 | Beta-adrenergic antagonism modulates functional connectivity in the default mode network of individuals with and without autism spectrum disorder. ( Beversdorf, DQ; Christ, SE; Ferguson, BJ; Hegarty, JP; Johnson, JD; Rohowetz, LJ; Zamzow, RM, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sagar-Ouriaghli, I | 1 |
| Lievesley, K | 1 |
| Santosh, PJ | 1 |
| Zamzow, RM | 3 |
| Ferguson, BJ | 3 |
| Stichter, JP | 1 |
| Porges, EC | 1 |
| Ragsdale, AS | 2 |
| Lewis, ML | 2 |
| Beversdorf, DQ | 3 |
| Hegarty, JP | 1 |
| Rohowetz, LJ | 1 |
| Johnson, JD | 1 |
| Christ, SE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Trial of Propranolol in Older Adults With Primary Progressive Aphasia[NCT06066710] | Early Phase 1 | 20 participants (Anticipated) | Interventional | 2024-01-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for propranolol and Autism Spectrum Disorder
| Article | Year |
|---|---|
Propranolol for treating emotional, behavioural, autonomic dysregulation in children and adolescents with autism spectrum disorders.
Topics: Adolescent; Adrenergic beta-Antagonists; Aggression; Autism Spectrum Disorder; Autonomic Nervous Sys | 2018 |
2 trials available for propranolol and Autism Spectrum Disorder
| Article | Year |
|---|---|
Effects of propranolol on conversational reciprocity in autism spectrum disorder: a pilot, double-blind, single-dose psychopharmacological challenge study.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aggression; Anxiety; Autism Spectrum Disorder; Auton | 2016 |
Effects of acute beta-adrenergic antagonism on verbal problem solving in autism spectrum disorder and exploration of treatment response markers.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Anxiety; Autism Spectrum Disorder; Autonomic Nervous | 2017 |
1 other study available for propranolol and Autism Spectrum Disorder
| Article | Year |
|---|---|
Beta-adrenergic antagonism modulates functional connectivity in the default mode network of individuals with and without autism spectrum disorder.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Autism Spectrum Disorder; Brain; Brain Mapping; Fema | 2017 |