propranolol has been researched along with Asymmetric Septal Hypertrophy, Familial in 6 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Troponin T (TnT) mutations that cause familial hypertrophic cardiomyopathy (FHC) and sudden cardiac death frequently increase myofilament Ca2+ sensitivity, suggesting that their Ca2+-sensitizing effect contributes importantly to the FHC pathogenesis." | 1.33 | Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts--role of myofilament Ca2+ sensitivity increase. ( Knollmann, BC; Potter, JD; Sirenko, SG, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bratt, EL | 1 |
| Östman-Smith, I | 1 |
| Hill, MG | 1 |
| Sekhon, MK | 1 |
| Reed, KL | 1 |
| Anderson, CF | 1 |
| Borjon, ND | 1 |
| Tardiff, JC | 1 |
| Barber, BJ | 1 |
| Wang, Y | 1 |
| Pinto, JR | 1 |
| Solis, RS | 1 |
| Dweck, D | 1 |
| Liang, J | 1 |
| Diaz-Perez, Z | 1 |
| Ge, Y | 1 |
| Walker, JW | 1 |
| Potter, JD | 2 |
| Michele, DE | 1 |
| Gomez, CA | 1 |
| Hong, KE | 1 |
| Westfall, MV | 1 |
| Metzger, JM | 1 |
| Thaman, R | 1 |
| Elliott, PM | 1 |
| Shah, JS | 1 |
| Mist, B | 1 |
| Williams, L | 1 |
| Murphy, RT | 1 |
| McKenna, WJ | 1 |
| Frenneaux, MP | 1 |
| Sirenko, SG | 1 |
| Knollmann, BC | 1 |
1 trial available for propranolol and Asymmetric Septal Hypertrophy, Familial
| Article | Year |
|---|---|
Reversal of inappropriate peripheral vascular responses in hypertrophic cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiomyopathy, Hypertrophic, Familial; Clonidin | 2005 |
5 other studies available for propranolol and Asymmetric Septal Hypertrophy, Familial
| Article | Year |
|---|---|
Effects of lifestyle changes and high-dose β-blocker therapy on exercise capacity in children, adolescents, and young adults with hypertrophic cardiomyopathy.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aging; Blood Pressure; Cardiomyopathy, Hypertrophic, | 2015 |
Intrauterine Treatment of a Fetus with Familial Hypertrophic Cardiomyopathy Secondary to MYH7 Mutation.
Topics: Adrenergic beta-Antagonists; Adult; Cardiac Myosins; Cardiomyopathy, Hypertrophic, Familial; Echocar | 2015 |
Generation and functional characterization of knock-in mice harboring the cardiac troponin I-R21C mutation associated with hypertrophic cardiomyopathy.
Topics: Amino Acid Substitution; Animals; Anti-Arrhythmia Agents; Calcium; Cardiomyopathy, Hypertrophic, Fam | 2012 |
Cardiac dysfunction in hypertrophic cardiomyopathy mutant tropomyosin mice is transgene-dependent, hypertrophy-independent, and improved by beta-blockade.
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Cardiomyopathy, Hypertrophic, Familial; Cells, Cultur | 2002 |
Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts--role of myofilament Ca2+ sensitivity increase.
Topics: Actin Cytoskeleton; Adrenergic beta-Antagonists; Animals; Calcium; Cardiomyopathy, Hypertrophic, Fam | 2006 |