propranolol has been researched along with Astrocytoma in 16 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of mastoparan on phosphatidylcholine hydrolysis was examined in 1321N1 human astrocytoma cells." | 7.69 | Mastoparan-induced phosphatidylcholine hydrolysis by phospholipase D activation in human astrocytoma cells. ( Mizuno, K; Nakahata, N; Ohizumi, Y, 1995) |
| "In an inositol-depleted 1321 N1 astrocytoma cell line, propranolol at 0." | 7.68 | Subcellular distribution of agonist-stimulated phosphatidylinositol synthesis in 1321 N1 astrocytoma cells. ( Downes, CP; Sillence, DJ, 1993) |
| "Norepinephrine, epinephrine, and histamine cause a rapid increase in the concentration of adenosine 3':5'-cyclic monophosphate (cAMP) in a tumor astrocyte cell line derived from a primary culture of a human glioblastoma multiforme." | 7.65 | Regulation of adenosine 3':5'-cyclic monophosphate concentration in cultured human astrocytoma cells by catecholamines and histamine. ( Clark, RB; Perkins, JP, 1971) |
| " The effect of mastoparan on phosphatidylcholine hydrolysis was examined in 1321N1 human astrocytoma cells." | 3.69 | Mastoparan-induced phosphatidylcholine hydrolysis by phospholipase D activation in human astrocytoma cells. ( Mizuno, K; Nakahata, N; Ohizumi, Y, 1995) |
| "In an inositol-depleted 1321 N1 astrocytoma cell line, propranolol at 0." | 3.68 | Subcellular distribution of agonist-stimulated phosphatidylinositol synthesis in 1321 N1 astrocytoma cells. ( Downes, CP; Sillence, DJ, 1993) |
| "We have shown previously that the major source of diglyceride (DG) formed following muscarinic receptor (mAChR) stimulation of 1321N1 astrocytoma cells is phosphatidylcholine (PC) rather than the phosphoinositides (Martinson, E." | 3.68 | Rapid protein kinase C-dependent activation of phospholipase D leads to delayed 1,2-diglyceride accumulation. ( Brown, JH; Martinson, EA; Trilivas, I, 1990) |
| "C6-2B rat astrocytoma cells were used to test whether the increase of cellular nerve growth factor (NGF) content and secretion induced by isoproterenol treatment are associated with an increase in the content of mRNA that encodes NGF (NGF mRNA)." | 3.67 | Beta adrenergic and prostaglandin receptor activation increases nerve growth factor mRNA content in C6-2B rat astrocytoma cells. ( Brooker, G; Costa, E; Dal Toso, R; De Bernardi, MA; Mocchetti, I, 1988) |
| "The characteristics of the effects of catecholamines, prostaglandins, and adenosine on the adenosine 3',5'-monophosphate (cAMP) content of human astrocytoma cells are described." | 3.65 | Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells. ( Clark, RB; Cubeddu, L; Johnson, GL; Ortmann, R; Perkins, JP; Su, YF, 1975) |
| "Norepinephrine, epinephrine, and histamine cause a rapid increase in the concentration of adenosine 3':5'-cyclic monophosphate (cAMP) in a tumor astrocyte cell line derived from a primary culture of a human glioblastoma multiforme." | 3.65 | Regulation of adenosine 3':5'-cyclic monophosphate concentration in cultured human astrocytoma cells by catecholamines and histamine. ( Clark, RB; Perkins, JP, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (81.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barovsky, K | 1 |
| Brooker, G | 3 |
| McKenzie, RC | 1 |
| Brophy, PJ | 1 |
| Sillence, DJ | 1 |
| Downes, CP | 1 |
| Mizuno, K | 1 |
| Nakahata, N | 1 |
| Ohizumi, Y | 1 |
| Nickols, GA | 1 |
| Clark, RB | 3 |
| Su, YF | 2 |
| Ortmann, R | 1 |
| Cubeddu, L | 1 |
| Johnson, GL | 3 |
| Perkins, JP | 5 |
| Oey, J | 1 |
| Harden, TK | 2 |
| Wolfe, BB | 1 |
| Molinoff, PB | 1 |
| Martinson, EA | 1 |
| Trilivas, I | 1 |
| Brown, JH | 1 |
| Dal Toso, R | 1 |
| De Bernardi, MA | 1 |
| Costa, E | 1 |
| Mocchetti, I | 1 |
| Balmforth, AJ | 1 |
| Ball, SG | 1 |
| Freshney, RI | 1 |
| Graham, DI | 1 |
| McNamee, HB | 1 |
| Vaughan, PF | 1 |
| Opler, LA | 1 |
| Makman, MH | 1 |
| Uzunov, P | 1 |
| Shein, HM | 1 |
| Weiss, B | 1 |
| Gross, R | 1 |
16 other studies available for propranolol and Astrocytoma
| Article | Year |
|---|---|
(-)-[125I]-iodopindolol, a new highly selective radioiodinated beta-adrenergic receptor antagonist: measurement of beta-receptors on intact rat astrocytoma cells.
Topics: Adrenergic beta-Antagonists; Animals; Astrocytoma; Binding Sites; Cells, Cultured; Iodine Radioisoto | 1980 |
Isoproterenol stimulates lipid methylation in C6 cells without affecting membrane fluidity.
Topics: Animals; Astrocytoma; Cyclic AMP; Electron Spin Resonance Spectroscopy; Isoproterenol; Lipid Metabol | 1983 |
Subcellular distribution of agonist-stimulated phosphatidylinositol synthesis in 1321 N1 astrocytoma cells.
Topics: Astrocytoma; Carbachol; Humans; Inositol; Lithium; Phosphatidylinositols; Propranolol; Tumor Cells, | 1993 |
Mastoparan-induced phosphatidylcholine hydrolysis by phospholipase D activation in human astrocytoma cells.
Topics: Animals; Astrocytoma; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Hydrolysis; Inter | 1995 |
Induction of refractoriness to isoproterenol by prior treatment of C6-2B rat astrocytoma cells with cholera toxin.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Astrocytoma; Cell Line; Cholera Toxin; Cycl | 1979 |
Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Astrocytoma; Catecholamines; Cells, Cultured; Cyclic AM | 1975 |
Noradrenaline-refractoriness in cultured glioma cells.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cells, Cultured; Cyclic AMP; Glioma; Neoplasms, Experimental; | 1976 |
Regulation of adenosine 3':5'-monophosphate content of rous sarcoma virus-transformed human astrocytoma cells. Effects of cholera toxin on the responsiveness to catecholamines and prostaglandins.
Topics: Adenylyl Cyclases; Astrocytoma; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Choler | 1978 |
Role of beta-adrenergic receptors in catecholamine-induced desensitization of adenylate cyclase in human astrocytoma cells.
Topics: Adenylyl Cyclases; Astrocytoma; Cell Line; Cyclic AMP; Humans; Isoproterenol; Kinetics; Propranolol; | 1978 |
Rapid protein kinase C-dependent activation of phospholipase D leads to delayed 1,2-diglyceride accumulation.
Topics: Animals; Astrocytoma; Carbachol; Cell Line; Choline; Diglycerides; Enzyme Activation; Kinetics; Phos | 1990 |
Beta adrenergic and prostaglandin receptor activation increases nerve growth factor mRNA content in C6-2B rat astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Astrocytoma; Cell Line; Isoproterenol; Male; Mice | 1988 |
D-1 dopaminergic and beta-adrenergic stimulation of adenylate cyclase in a clone derived from the human astrocytoma cell line G-CCM.
Topics: Adenylyl Cyclases; Astrocytoma; Cell Line; Clone Cells; Cyclic AMP; Dopamine; Flupenthixol; Humans; | 1986 |
Regulation of adenosine 3':5'-cyclic monophosphate concentration in cultured human astrocytoma cells by catecholamines and histamine.
Topics: Astrocytoma; Cells, Cultured; Clone Cells; Cyclic AMP; Depression, Chemical; Epinephrine; Glioblasto | 1971 |
Mediation by cyclic AMP of hormone-stimulated glycogenolysis in cultured rat astrocytoma cells.
Topics: Adenosine Triphosphate; Animals; Astrocytoma; Butyrates; Clone Cells; Cyclic AMP; Drug Antagonism; E | 1972 |
Cyclic AMP phosphodiesterase in cloned astrocytoma cells: norepinephrine induces a specific enzyme form.
Topics: Animals; Astrocytoma; Cell Line; Clone Cells; Cyclic AMP; Cycloheximide; Electrophoresis, Polyacryla | 1973 |
Regulation of adenosine 3':5'-monophosphate content in human astrocytoma cells by adenosine and the adenine nucleotides.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Astrocyt | 1974 |