Page last updated: 2024-11-03

propranolol and Ascites

propranolol has been researched along with Ascites in 50 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Ascites: Accumulation or retention of free fluid within the peritoneal cavity.

Research Excerpts

ExcerptRelevanceReference
"In recent years, concerns have been raised on the potential adverse effects of nonselective beta-blockers, and particularly carvedilol, on renal perfusion and survival in decompensated cirrhosis with ascites."9.41Conversion of Propranolol to Carvedilol Improves Renal Perfusion and Outcome in Patients With Cirrhosis and Ascites. ( Aggelis, N; Baltayiannis, G; Christaki, M; Christodoulou, D; Despotis, G; Fillipas-Ntekouan, S; Fotopoulos, A; Kalambokis, GN; Koustousi, C; Lakkas, L; Michalis, LK; Milionis, H; Pappas, K; Sergianiti, F; Tsiakas, I; Tsiouris, S; Xourgia, X, 2021)
"The effect of spironolactone on esophageal variceal pressure (VP) in patients without ascites was investigated."9.08The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites. ( Fevery, J; Lijnen, P; Nevens, F; VanBilloen, H, 1996)
"It has been suggested that propranolol may have a protective effect on the development of spontaneous bacterial peritonitis by increasing the motility of the bowel and lowering the pressure of the portal vein."7.73Spontaneous bacterial peritonitis in cirrhotic patients: Is prophylactic propranolol therapy beneficial? ( Archimandritis, AJ; Burroughs, AK; Cholongitas, E; Manesis, EK; Papatheodoridis, GV, 2006)
"Propranolol hydrochloride is reported to lower portal pressure and inhibit renin secretion in patients with chronic liver disease, actions that might lessen the tendency to ascites formation."7.67Propranolol in the treatment of cirrhotic ascites. ( Rector, WG; Reynolds, TB, 1984)
"To determine the effect of massive cocaine intoxication on lung water and ascites accumulation and the effect of beta- and alpha-adrenergic blockade on survival in massive cocaine intoxication in the mouse."7.67Increased lung water and ascites after massive cocaine overdosage in mice and improved survival related to beta-adrenergic blockage. ( Ptashne, KA; Robin, ED; Wong, RJ, 1989)
"Propranolol has been used as prophylaxis for variceal bleeding in patients with cirrhosis."6.82A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis. ( Baik, SK; Jang, JY; Jeong, SW; Kim, DJ; Kim, MY; Kim, SG; Kim, TY; Kim, YS; Lee, B; Seo, YS; Sohn, JH; Suk, KT; Um, SH, 2016)
" First-line therapies include carvedilol or propranolol to prevent variceal bleeding, lactulose for hepatic encephalopathy, combination aldosterone antagonists and loop diuretics for ascites, and terlipressin for hepatorenal syndrome."5.41Diagnosis and Management of Cirrhosis and Its Complications: A Review. ( Parikh, ND; Tapper, EB, 2023)
"In recent years, concerns have been raised on the potential adverse effects of nonselective beta-blockers, and particularly carvedilol, on renal perfusion and survival in decompensated cirrhosis with ascites."5.41Conversion of Propranolol to Carvedilol Improves Renal Perfusion and Outcome in Patients With Cirrhosis and Ascites. ( Aggelis, N; Baltayiannis, G; Christaki, M; Christodoulou, D; Despotis, G; Fillipas-Ntekouan, S; Fotopoulos, A; Kalambokis, GN; Koustousi, C; Lakkas, L; Michalis, LK; Milionis, H; Pappas, K; Sergianiti, F; Tsiakas, I; Tsiouris, S; Xourgia, X, 2021)
"100) rebled from esophageal varices within a mean time of 8."5.27[Propranolol prevention of hemorrhagic recurrence caused by rupture of esophageal varices: worsened prognosis in ascites and jaundice]. ( Attali, P; Buffet, C; Etienne, JP; Ink, O; Pelletier, G; Servent, L, 1985)
"The effect of spironolactone on esophageal variceal pressure (VP) in patients without ascites was investigated."5.08The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites. ( Fevery, J; Lijnen, P; Nevens, F; VanBilloen, H, 1996)
"It has been suggested that propranolol may have a protective effect on the development of spontaneous bacterial peritonitis by increasing the motility of the bowel and lowering the pressure of the portal vein."3.73Spontaneous bacterial peritonitis in cirrhotic patients: Is prophylactic propranolol therapy beneficial? ( Archimandritis, AJ; Burroughs, AK; Cholongitas, E; Manesis, EK; Papatheodoridis, GV, 2006)
"Propranolol hydrochloride is reported to lower portal pressure and inhibit renin secretion in patients with chronic liver disease, actions that might lessen the tendency to ascites formation."3.67Propranolol in the treatment of cirrhotic ascites. ( Rector, WG; Reynolds, TB, 1984)
"To determine the effect of massive cocaine intoxication on lung water and ascites accumulation and the effect of beta- and alpha-adrenergic blockade on survival in massive cocaine intoxication in the mouse."3.67Increased lung water and ascites after massive cocaine overdosage in mice and improved survival related to beta-adrenergic blockage. ( Ptashne, KA; Robin, ED; Wong, RJ, 1989)
"Carvedilol is a non-selective beta-blocker (NSBB) acting on hyperdynamic circulation/splanchnic vasodilation and on intrahepatic resistance."3.01Carvedilol as the new non-selective beta-blocker of choice in patients with cirrhosis and portal hypertension. ( La Mura, V; Reiberger, T; Turco, L; Vitale, G, 2023)
"Propranolol has been used as prophylaxis for variceal bleeding in patients with cirrhosis."2.82A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis. ( Baik, SK; Jang, JY; Jeong, SW; Kim, DJ; Kim, MY; Kim, SG; Kim, TY; Kim, YS; Lee, B; Seo, YS; Sohn, JH; Suk, KT; Um, SH, 2016)
"Pregnancy is rare in women with decompensated chronic liver disease."2.47Successful pregnancy outcome in decompensated chronic liver disease with portal vein thrombosis: case report and review of literature. ( Hussain, R; Kamani, L; Kumar, M; Siddique, S, 2011)
"Carvedilol is a potent noncardioselective beta-blocker, with weak vasodilating properties because of alpha 1 blockade."2.46The role of carvedilol in the management of portal hypertension. ( Hayes, PC; Tripathi, D, 2010)
"Ascites, variceal bleeding, hepatic encephalopathy, and hepatorenal syndrome are among the complications you are likely to encounter when caring for a patient with cirrhosis."1.42Cirrhosis complications: keeping them under control. ( Eliacin, I; Kashan, S; Minor, SE; Whisenant, EB, 2015)
"The so-called "low T3 syndrome" has frequently been reported in patients with cirrhosis."1.28"Low T3 syndrome" in cirrhosis: effect of beta-blockade. ( Bellanova, B; Bernardi, M; De Palma, R; Gasbarrini, G; Pesa, O; Tame, MR; Trevisani, F; Vecchi, F, 1989)
"100) rebled from esophageal varices within a mean time of 8."1.27[Propranolol prevention of hemorrhagic recurrence caused by rupture of esophageal varices: worsened prognosis in ascites and jaundice]. ( Attali, P; Buffet, C; Etienne, JP; Ink, O; Pelletier, G; Servent, L, 1985)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199015 (30.00)18.7374
1990's3 (6.00)18.2507
2000's4 (8.00)29.6817
2010's22 (44.00)24.3611
2020's6 (12.00)2.80

Authors

AuthorsStudies
Singh, V1
Kumar, P1
Verma, N1
Vijayvergiya, R1
Singh, A1
Bhalla, A1
Turco, L1
Reiberger, T2
Vitale, G1
La Mura, V1
Tapper, EB1
Parikh, ND1
Danielsen, KV1
Nabilou, P1
Wiese, SS1
Hove, JD1
Bendtsen, F4
Møller, S4
Yoo, JJ1
Kim, SG2
Kim, YS2
Lee, B2
Jeong, SW2
Jang, JY2
Lee, SH1
Kim, HS1
Jun, BG1
Kim, YD1
Cheon, GJ1
Kalambokis, GN3
Christaki, M1
Tsiakas, I1
Despotis, G1
Fillipas-Ntekouan, S1
Fotopoulos, A1
Tsiouris, S1
Xourgia, X1
Lakkas, L1
Pappas, K1
Michalis, LK1
Sergianiti, F1
Baltayiannis, G3
Christodoulou, D3
Koustousi, C1
Aggelis, N1
Milionis, H1
Villanueva, C1
Albillos, A1
Genescà, J1
Garcia-Pagan, JC2
Calleja, JL1
Aracil, C1
Bañares, R1
Morillas, RM1
Poca, M1
Peñas, B1
Augustin, S1
Abraldes, JG2
Alvarado, E1
Torres, F1
Bosch, J2
Hsu, SJ1
Huang, HC1
Robins, A1
Bowden, A1
Watson, W1
Smith, F1
Gelson, W1
Griffiths, W1
Kimer, N1
Feineis, M1
Celtik, C1
Durmaz, O1
Oner, N1
Yavuz, T1
Gökce, S1
Aydogan, A1
Nisli, K1
Emiroglu, HH1
Ömeroglu, RE1
Sökücü, S1
Minor, SE1
Eliacin, I1
Kashan, S1
Whisenant, EB1
Christou, L2
Mandorfer, M1
Kim, TY1
Sohn, JH1
Um, SH1
Seo, YS1
Baik, SK1
Kim, MY1
Suk, KT1
Kim, DJ1
Shukla, R1
Kramer, J1
Cao, Y1
Ying, J1
Tansel, A1
Walder, A1
Advani, S1
El-Serag, HB1
Kanwal, F1
Tripathi, D1
Hayes, PC1
Sersté, T2
Melot, C2
Francoz, C2
Durand, F2
Rautou, PE2
Valla, D2
Moreau, R2
Lebrec, D3
Thevenot, T1
Cervoni, JP1
Monnet, E1
Sheppard, F1
Martino, VD1
Krag, A2
Kurt, M1
Lo, GH1
Angeli, P1
Agustín, A1
Javier, Z1
Kumar, M1
Kamani, L1
Hussain, R1
Siddique, S1
Burroughs, AK2
Tarantino, I1
Turnes, J1
Rodés, J1
Soylu, AR1
Dökmeci, G1
Tezel, A1
Amuca, H1
Umit, H1
Nidegger, D1
Ragot, S1
Berthelémy, P1
Masliah, C1
Pilette, C1
Martin, T1
Bianchi, A1
Paupard, T1
Silvain, C1
Beauchant, M1
Cholongitas, E1
Papatheodoridis, GV1
Manesis, EK1
Archimandritis, AJ1
Rector, WG1
Reynolds, TB1
Eisenburg, J1
Nevens, F1
Lijnen, P1
VanBilloen, H1
Fevery, J1
Klein, AM1
Holzman, IR1
Austin, EM1
Levy, M1
Sabbah, A1
Poynard, T1
Calès, P2
Pasta, L1
Ideo, G1
Pascal, JP1
Pagliaro, L1
Bondarenko, IP1
Dubinskiĭ, AA1
Tereshkin, IG1
Bernardi, M1
De Palma, R1
Trevisani, F1
Pesa, O1
Tame, MR1
Bellanova, B1
Vecchi, F1
Gasbarrini, G1
Robin, ED1
Wong, RJ1
Ptashne, KA1
Kandel, G1
Diamant, NE1
Braillon, A1
Tribout, B1
Reix, N1
Capron, JP1
Scheurlen, M1
Egberts, EH1
Dölle, W1
Ink, O1
Servent, L1
Attali, P1
Pelletier, G1
Buffet, C1
Etienne, JP1
Witty, RT1
Davis, JO1
Shade, RE1
Johnson, JA1
Prewitt, RL1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites[NCT02649335]Phase 3190 participants (Actual)Interventional2015-07-01Completed
A Novel Algorithm to Stratify Clinical Decompensation Risk in Patients With Compensated Advanced Chronic Liver Disease (CHESS2108)[NCT05100485]1,000 participants (Actual)Observational2022-01-01Completed
Multicenter, Randomized, Double-blind, Placebo-controlled Study on the Effectiveness of Treatment With Beta-blockers to Prevent Decompensation of Cirrhosis With Portal Hypertension[NCT01059396]Phase 4201 participants (Actual)Interventional2010-01-28Completed
CHESS-SAVE Score to Stratify Decompensation Risk in Compensated Advanced Chronic Liver Disease: an International Multicenter Study (CHESS2102)[NCT04975477]1,000 participants (Anticipated)Observational2021-07-16Not yet recruiting
The Effect of Preoperative Beta Blocker Use on Intraoperative Hemodynamics and Postoperative Renal Function in End-stage Liver Disease Patients Undergoing Liver Transplantation[NCT03633812]477 participants (Anticipated)Observational [Patient Registry]2016-10-28Recruiting
Treatment of Type I Hepatorenal Syndrome (HRS) With Pentoxyfylline: A Placebo Controlled, Blinded Pilot Study[NCT02123576]12 participants (Actual)Interventional2014-04-30Terminated (stopped due to Poor enrollment of study population)
Pilot Study to Evaluate the Correlation Between ¹³C Methacetin Breath Test (MBT) and HVPG Measurement as a Tool for Identifying Responders to Portal Hypertension Therapy[NCT01851252]Phase 119 participants (Actual)Interventional2013-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Serum Creatinine From Baseline

(NCT02123576)
Timeframe: baseline and 14 days

Interventiong/dL (Mean)
Treatment0.48
Placebo0.03

Incidence of Treatment Failure

Defined as creatinine level above baseline value after day 7, dialysis or death (NCT02123576)
Timeframe: up to day 14

InterventionParticipants (Count of Participants)
Treatment3
Placebo3

Number of Participants With Combined Outcome of Treatment Success and Partial Response

We define as serum creatinine level decreased by >50% from baseline but not to <1.5 mg/dL, without dialysis or HRS recurrence (NCT02123576)
Timeframe: 14 days

InterventionParticipants (Count of Participants)
Treatment1
Placebo2

Number of Participants With Treatment Success

We define this as a decrease in serum creatinine level to <1.5 mg/dL without dialysis or death (NCT02123576)
Timeframe: 14 days

InterventionParticipants (Count of Participants)
Treatment1
Placebo1

Overall Survival

This will be the combination of transplant free survival and those patients who received liver transplant (NCT02123576)
Timeframe: up to 1 year

Interventiondays (Mean)
Treatment102
Placebo59

Transplant Free Survival

(NCT02123576)
Timeframe: day 30 and 180

Interventiondays (Mean)
Treatment80
Placebo36

Reviews

9 reviews available for propranolol and Ascites

ArticleYear
Carvedilol as the new non-selective beta-blocker of choice in patients with cirrhosis and portal hypertension.
    Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:6

    Topics: Adrenergic beta-Antagonists; Ascites; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal H

2023
Diagnosis and Management of Cirrhosis and Its Complications: A Review.
    JAMA, 2023, 05-09, Volume: 329, Issue:18

    Topics: Adult; Ascites; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hepatic Enc

2023
Management of ascites in patients with liver cirrhosis: recent evidence and controversies.
    Journal of the Chinese Medical Association : JCMA, 2013, Volume: 76, Issue:3

    Topics: Ascites; Hepatorenal Syndrome; Humans; Liver Cirrhosis; Lypressin; Midodrine; Portasystemic Shunt, T

2013
Beta-blockers in cirrhosis and refractory ascites: a retrospective cohort study and review of the literature.
    Scandinavian journal of gastroenterology, 2015, Volume: 50, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Ascites; Case-Control Studies; Esophageal and Gastric Varices; Fe

2015
The role of carvedilol in the management of portal hypertension.
    European journal of gastroenterology & hepatology, 2010, Volume: 22, Issue:8

    Topics: Antihypertensive Agents; Ascites; Benzopyrans; Carbazoles; Carvedilol; Drug Therapy, Combination; Et

2010
Successful pregnancy outcome in decompensated chronic liver disease with portal vein thrombosis: case report and review of literature.
    European journal of gastroenterology & hepatology, 2011, Volume: 23, Issue:7

    Topics: Adult; Antiviral Agents; Ascites; Blood Transfusion; Esophageal and Gastric Varices; Female; Hepatit

2011
[Typical risks in the treatment of acute and chronic liver diseases].
    Der Internist, 1982, Volume: 23, Issue:3

    Topics: Androgens; Ascites; Cholestyramine Resin; Cimetidine; Disseminated Intravascular Coagulation; Diuret

1982
Beta-adrenergic-antagonist drugs in the prevention of gastrointestinal bleeding in patients with cirrhosis and esophageal varices. An analysis of data and prognostic factors in 589 patients from four randomized clinical trials. Franco-Italian Multicenter
    The New England journal of medicine, 1991, May-30, Volume: 324, Issue:22

    Topics: Adrenergic beta-Antagonists; Ascites; Esophageal and Gastric Varices; Female; Gastrointestinal Hemor

1991
A clinical view of recent advances in ascites.
    Journal of clinical gastroenterology, 1986, Volume: 8, Issue:1

    Topics: Animals; Ascites; Ascitic Fluid; Bacterial Infections; Blood Volume; Body Water; Extracellular Space

1986

Trials

9 trials available for propranolol and Ascites

ArticleYear
Propranolol vs. band ligation for primary prophylaxis of variceal hemorrhage in cirrhotic patients with ascites: a randomized controlled trial.
    Hepatology international, 2022, Volume: 16, Issue:4

    Topics: Acute Kidney Injury; Ascites; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; L

2022
Conversion of Propranolol to Carvedilol Improves Renal Perfusion and Outcome in Patients With Cirrhosis and Ascites.
    Journal of clinical gastroenterology, 2021, 09-01, Volume: 55, Issue:8

    Topics: Ascites; Carvedilol; Humans; Kidney; Liver Cirrhosis; Perfusion; Propranolol

2021
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:11

    Topics: Adult; Antihypertensive Agents; Ascites; Carbazoles; Carvedilol; End Stage Liver Disease; Esophageal

2016
Beta-blockers cause paracentesis-induced circulatory dysfunction in patients with cirrhosis and refractory ascites: a cross-over study.
    Journal of hepatology, 2011, Volume: 55, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Ascites; Blood Pressure; Cardiovascular Diseases; Combined Modali

2011
Cirrhosis and bleeding: the need for very early management.
    Journal of hepatology, 2003, Volume: 39, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Ascites; Double-Blind Method; Esophageal and Gastric Varic

2003
The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Ascites; Atrial Natriuretic Factor;

1996
Beta-adrenergic-antagonist drugs in the prevention of gastrointestinal bleeding in patients with cirrhosis and esophageal varices. An analysis of data and prognostic factors in 589 patients from four randomized clinical trials. Franco-Italian Multicenter
    The New England journal of medicine, 1991, May-30, Volume: 324, Issue:22

    Topics: Adrenergic beta-Antagonists; Ascites; Esophageal and Gastric Varices; Female; Gastrointestinal Hemor

1991
Propranolol prevents first gastrointestinal bleeding in non-ascitic cirrhotic patients. Final report of a multicenter randomized trial. The Italian Multicenter Project for Propranolol in Prevention of Bleeding.
    Journal of hepatology, 1989, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Aged; Ascites; Clinical Trials as Topic; Female; Follow-Up Studies; Gastrointesti

1989

Other Studies

33 other studies available for propranolol and Ascites

ArticleYear
Effect of beta-blockers on multiple haemodynamics in cirrhosis: A cross-over study by MR-imaging and hepatic vein catheterization.
    Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:10

    Topics: Adrenergic beta-Antagonists; Ascites; Catheterization; Cross-Over Studies; Hemodynamics; Hepatic Vei

2023
Propranolol plus endoscopic ligation for variceal bleeding in patients with significant ascites: Propensity score matching analysis.
    Medicine, 2020, Volume: 99, Issue:5

    Topics: Adrenergic beta-Antagonists; Ascites; Combined Modality Therapy; Endoscopy; Esophageal and Gastric V

2020
Beta-blockers in cirrhosis patients with refractory ascites.
    Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:5

    Topics: Adrenergic beta-Antagonists; Ascites; Contraindications; Female; Humans; Liver Cirrhosis; Male; Prop

2014
Investigation of cardiomyopathy in children with cirrhotic and noncirrhotic portal hypertension.
    Journal of pediatric gastroenterology and nutrition, 2015, Volume: 60, Issue:2

    Topics: Adolescent; Antihypertensive Agents; Ascites; Blood Pressure; Cardiomyopathies; Case-Control Studies

2015
Cirrhosis complications: keeping them under control.
    The Journal of family practice, 2015, Volume: 64, Issue:6

    Topics: Antihypertensive Agents; Ascites; Diuretics; Furosemide; Hemorrhage; Hepatic Encephalopathy; Humans;

2015
Red signs and not severity of cirrhosis should determine non-selective β-blocker treatment in Child-Pugh C cirrhosis with small varices: increased risk of hepatorenal syndrome and death beyond 6 months of propranolol use.
    Gut, 2016, Volume: 65, Issue:7

    Topics: Adrenergic beta-Antagonists; Ascites; Child; Esophageal and Gastric Varices; Hepatorenal Syndrome; H

2016
Propranolol use beyond 6 months increases mortality in patients with Child-Pugh C cirrhosis and ascites.
    Hepatology (Baltimore, Md.), 2016, Volume: 64, Issue:5

    Topics: Ascites; Child; Fibrosis; Humans; Liver Cirrhosis; Propranolol

2016
Nonselective beta blockers in patients with ascites: implications of a nationwide study.
    Liver international : official journal of the International Association for the Study of the Liver, 2016, Volume: 36, Issue:9

    Topics: Adrenergic beta-Antagonists; Ascites; Humans; Propranolol

2016
Risk and Predictors of Variceal Bleeding in Cirrhosis Patients Receiving Primary Prophylaxis With Non-Selective Beta-Blockers.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:12

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Ascites; Cohort Studies; Comorbidity; Dose-Response

2016
Deleterious effects of beta-blockers on survival in patients with cirrhosis and refractory ascites.
    Hepatology (Baltimore, Md.), 2010, Volume: 52, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Ascites; Contraindications; Female; Follow-Up Studies; Humans; Hy

2010
Is this really the end of beta-blockers in patients with cirrhosis and refractory ascites?
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:2

    Topics: Adrenergic beta-Antagonists; Ascites; Contraindications; Humans; Hypertension, Portal; Liver Cirrhos

2011
Does cardiac dysfunction explain deleterious effects of beta-blockers in cirrhosis and refractory ascites?
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:1

    Topics: Adrenergic beta-Antagonists; Ascites; Cardiac Output; Heart Diseases; Humans; Liver Cirrhosis; Propr

2011
Deleterious effects of beta-blockers on survival in patients with cirrhosis and refractory ascites.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:4

    Topics: Adrenergic beta-Antagonists; Ascites; Humans; Liver Cirrhosis; Propranolol; Treatment Outcome

2011
Effects of beta-blockers on survival for patients with cirrhosis and refractory ascites.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:3

    Topics: Adrenergic beta-Antagonists; Ascites; Contraindications; Esophageal and Gastric Varices; Gastrointes

2011
β-blockers and refractory ascites in cirrhosis: the message of a team of true scientists.
    Journal of hepatology, 2011, Volume: 55, Issue:4

    Topics: Adrenergic beta-Antagonists; Ascites; Bacterial Infections; Cardiovascular Diseases; Female; Hepator

2011
Beta-blockers in patients with cirrhosis and refractory ascites.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:5

    Topics: Adrenergic beta-Antagonists; Ascites; Contraindications; Humans; Liver Cirrhosis; Propranolol

2011
Betablockers induce cardiac chronotropic incompetence.
    Journal of hepatology, 2012, Volume: 56, Issue:1

    Topics: Adrenergic beta-Antagonists; Ascites; Cardiovascular Diseases; Female; Humans; Liver Cirrhosis; Male

2012
Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis.
    Hepatology (Baltimore, Md.), 2003, Volume: 37, Issue:4

    Topics: Antihypertensive Agents; Ascites; Bacterial Infections; Cohort Studies; Drug Therapy, Combination; F

2003
Propranolol does not affect incidence of spontaneous bacterial peritonitis in cirrhotic patients with ascites.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Ascites; Bacterial Translocation; Esophageal and Gastric V

2003
Spontaneous bacterial peritonitis in cirrhotic patients: Is prophylactic propranolol therapy beneficial?
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Ascites; Ascitic Fluid; Bacterial Infections; Chi-Square Distribu

2006
Propranolol in the treatment of cirrhotic ascites.
    Archives of internal medicine, 1984, Volume: 144, Issue:9

    Topics: Ascites; Furosemide; Humans; Liver Cirrhosis; Natriuresis; Propranolol; Triamterene

1984
Fetal tachycardia prior to the development of hydrops--attempted pharmacologic cardioversion: case report.
    American journal of obstetrics and gynecology, 1979, Jun-01, Volume: 134, Issue:3

    Topics: Ascites; Digoxin; Edrophonium; Female; Fetal Diseases; Humans; Infant, Newborn; Male; Maternal-Fetal

1979
Sodium retention in dogs with cirrhosis and ascites: efferent mechanisms.
    The American journal of physiology, 1977, Volume: 233, Issue:6

    Topics: Aldosterone; Animals; Ascites; Blood Pressure; Cardiac Output; Denervation; Dogs; Estrogens; Female;

1977
[Letter: action of beta-blocking agents in decompensated cirrhosis].
    La Nouvelle presse medicale, 1976, Jan-10, Volume: 5, Issue:2

    Topics: Ascites; Drug Evaluation; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Propranolol; Water-Ele

1976
Propranolol in the prevention of ascites.
    Lancet (London, England), 1991, Aug-24, Volume: 338, Issue:8765

    Topics: Ascites; Follow-Up Studies; Humans; Liver Diseases; Propranolol

1991
[The use of anaprilin for the correction of portal hypertension in liver cirrhosis].
    Vrachebnoe delo, 1989, Issue:11

    Topics: Adult; Aged; Ascites; Drug Evaluation; Female; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hy

1989
"Low T3 syndrome" in cirrhosis: effect of beta-blockade.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:7

    Topics: Adult; Aged; Ascites; Euthyroid Sick Syndromes; Female; Gastrointestinal Hemorrhage; Humans; Liver C

1989
Increased lung water and ascites after massive cocaine overdosage in mice and improved survival related to beta-adrenergic blockage.
    Annals of internal medicine, 1989, Feb-01, Volume: 110, Issue:3

    Topics: Animals; Ascites; Cocaine; Extracellular Space; Lung; Male; Mice; Phentolamine; Propranolol; Pulmona

1989
[Are metoclopramide and propranolol contraindicated, like nonsteroidal anti-inflammatory agents, in patients with cirrhosis and ascites?].
    Gastroenterologie clinique et biologique, 1986, Volume: 10, Issue:3

    Topics: Anti-Inflammatory Agents; Ascites; Diuretics; Drug Therapy, Combination; Humans; Liver Cirrhosis; Me

1986
[Indications for surgery in portal hypertension from the internist's viewpoint].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1985, Volume: 56, Issue:7

    Topics: Ascites; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal;

1985
[Propranolol prevention of hemorrhagic recurrence caused by rupture of esophageal varices: worsened prognosis in ascites and jaundice].
    Gastroenterologie clinique et biologique, 1985, Volume: 9, Issue:11

    Topics: Ascites; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Jaundice; Live

1985
Mechanisms regulating renin release in dogs with thoracic caval constriction.
    Circulation research, 1972, Volume: 31, Issue:3

    Topics: Angiotensin II; Animals; Ascites; Blood Pressure; Constriction; Creatinine; Disease Models, Animal;

1972
[Therapeutic methods].
    Arquivos brasileiros de cardiologia, 1966, Volume: 19

    Topics: Amidohydrolases; Ascites; Diuretics; Edema; Heart Diseases; Humans; Hypertension; Propranolol; Water

1966