propranolol has been researched along with Aortic Diseases in 15 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Aortic Diseases: Pathological processes involving any part of the AORTA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the tolerability and efficacy of the investigational use of the angiotensin II receptor blocker losartan added to β-blockade (BB) to prevent progressive aortic root dilation in patients with Marfan syndrome (MFS)." | 9.17 | Losartan added to β-blockade therapy for aortic root dilation in Marfan syndrome: a randomized, open-label pilot study. ( Chen, CA; Chiu, HH; Chiu, SN; Hu, FC; Lin, MT; Lu, CW; Wang, JK; Wu, MH, 2013) |
| "To assess the tolerability and efficacy of the investigational use of the angiotensin II receptor blocker losartan added to β-blockade (BB) to prevent progressive aortic root dilation in patients with Marfan syndrome (MFS)." | 5.17 | Losartan added to β-blockade therapy for aortic root dilation in Marfan syndrome: a randomized, open-label pilot study. ( Chen, CA; Chiu, HH; Chiu, SN; Hu, FC; Lin, MT; Lu, CW; Wang, JK; Wu, MH, 2013) |
| "The effect of the beta-blocker propranolol and of bensonal, a barbituric acid derivative stimulating microsomal oxidation of the liver monooxygenase, was evaluated using the model of experimental myocardial infarction (EMI) in the presence of 3-month cholesterol atherosclerosis." | 3.67 | [Experimental myocardial infarction in atherosclerosis--various methods of pharmacological correction]. ( Irgashev, ShB, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lampropoulos, KM | 1 |
| Sokolis, DP | 1 |
| Dimitriou, CA | 1 |
| Katsimpoulas, M | 1 |
| Balafas, E | 1 |
| Agapaki, A | 1 |
| Karayannacos, PE | 1 |
| Boudoulas, H | 1 |
| Chiu, HH | 1 |
| Wu, MH | 1 |
| Wang, JK | 1 |
| Lu, CW | 1 |
| Chiu, SN | 1 |
| Chen, CA | 1 |
| Lin, MT | 1 |
| Hu, FC | 1 |
| Makhmudov, RM | 1 |
| Dolgov, VV | 1 |
| Voĭno-Iasenetskaia, TA | 1 |
| Ivanov, VO | 1 |
| Preobrazhenskiĭ, SN | 1 |
| Crozatier, B | 1 |
| Caillet, D | 1 |
| Bical, O | 1 |
| Spence, JD | 1 |
| Perkins, DG | 1 |
| Kline, RL | 1 |
| Adams, MA | 1 |
| Haust, MD | 1 |
| Simpson, CF | 1 |
| Boucek, RJ | 1 |
| Holdaas, H | 1 |
| DiBona, GF | 1 |
| Kiil, F | 1 |
| Tahernia, AC | 1 |
| Tachibana, H | 1 |
| Takaki, M | 1 |
| Lee, S | 1 |
| Ito, H | 1 |
| Yamaguchi, H | 1 |
| Suga, H | 1 |
| Thorén, PN | 1 |
| Irgashev, ShB | 1 |
| Potier, JC | 1 |
| Strong, WW | 1 |
| Moggio, RA | 1 |
| Stansel, HC | 1 |
| Murdoch, JL | 1 |
| Walker, BA | 1 |
| Halpern, BL | 1 |
| Kuzma, JW | 1 |
| McKusick, VA | 1 |
| Grassi, T | 1 |
| Tardito, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Open-label, Active Control Trial to Evaluate the Effect of LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan Syndrome[NCT00651235] | Phase 2 | 44 participants (Anticipated) | Interventional | 2007-02-28 | Recruiting | ||
| Thoracic Aortic Dilatation Syndromes - Diagnostic, Incidences, Morbidity, Mortality and Socioeconomical Observations.[NCT02111668] | 120 participants (Actual) | Observational [Patient Registry] | 2013-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for propranolol and Aortic Diseases
| Article | Year |
|---|---|
Cardiovascular anomalies in Marfan's syndrome: the role of echocardiography and beta-blockers.
Topics: Adolescent; Aortic Diseases; Auscultation; Child; Child, Preschool; Dilatation, Pathologic; Echocard | 1993 |
2 trials available for propranolol and Aortic Diseases
| Article | Year |
|---|---|
Losartan added to β-blockade therapy for aortic root dilation in Marfan syndrome: a randomized, open-label pilot study.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Angiotensin II Type 1 Receptor Blockers; Aortic | 2013 |
Cardiovascular anomalies in Marfan's syndrome: the role of echocardiography and beta-blockers.
Topics: Adolescent; Aortic Diseases; Auscultation; Child; Child, Preschool; Dilatation, Pathologic; Echocard | 1993 |
13 other studies available for propranolol and Aortic Diseases
| Article | Year |
|---|---|
The effect of propranolol on aortic structure and function in normotensive rats.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Aortic Diseases; Blood | 2012 |
[Effect of adrenaline on incorporation of 125I-LDL into the aorta].
Topics: Animals; Aorta; Aortic Diseases; Arteriosclerosis; Chinchilla; Epinephrine; Lipoproteins, LDL; Male; | 1984 |
Left ventricular adaptation to sustained pressure overload in the conscious dog.
Topics: Animals; Aortic Diseases; Arterial Occlusive Diseases; Blood Pressure; Dogs; Hemodynamics; Myocardia | 1984 |
Hemodynamic modification of aortic atherosclerosis. Effects of propranolol vs hydralazine in hypertensive hyperlipidemic rabbits.
Topics: Animals; Aortic Diseases; Arteriosclerosis; Cholesterol; Hemodynamics; Hydralazine; Hyperlipidemias; | 1984 |
The B-aminopropionitrile-fed turkey: a model for detecting potential drug action on arterial tissue.
Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Diseases; Disease Models, Ani | 1983 |
Effect of low-level renal nerve stimulation on renin release from nonfiltering kidneys.
Topics: Animals; Aortic Diseases; Constriction, Pathologic; Dogs; Female; Filtration; Kidney; Male; Metoprol | 1981 |
New mechanoenergetic evaluation of left ventricular contractility in in situ rat hearts.
Topics: Animals; Aortic Diseases; Cardiotonic Agents; Constriction, Pathologic; Dobutamine; Energy Metabolis | 1997 |
Characteristics of left ventricular receptors with nonmedullated vagal afferents in cats.
Topics: Animals; Aortic Diseases; Arterial Occlusive Diseases; Blood Pressure; Blood Transfusion; Cats; Hear | 1977 |
[Experimental myocardial infarction in atherosclerosis--various methods of pharmacological correction].
Topics: Administration, Oral; Animals; Aortic Diseases; Arteriosclerosis; Barbiturates; Coronary Disease; Dr | 1985 |
[Preventive action of an inhibitor of beta adrenergic receptors in the experimental aortic dissections induced in rats by penicillamine].
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Aortic Diseases; Penicillamine; Propranolol; Rats | 1969 |
Acute aortic dissection. Twelve-year medical and surgical experience.
Topics: Adult; Aged; Antihypertensive Agents; Aorta, Thoracic; Aortic Aneurysm; Aortic Diseases; Connecticut | 1974 |
Life expectancy and causes of death in the Marfan syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aortic Diseases; Cardiovascular Diseases; Child; Female; Human | 1972 |
[On the possibility of comparative measurement of peripheral blood flow. Analysis made on the first lead of the peripheral segmental plethysmogram].
Topics: Adult; Aged; Aortic Diseases; Axillary Artery; Female; Femoral Artery; Humans; Male; Middle Aged; Pl | 1970 |