propranolol has been researched along with Aortic Coarctation in 26 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Aortic Coarctation: A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of the nonselective beta blocker, propranolol, on coarctectomy-induced hypertension were evaluated relative to changes in cardiac function, sympathetic tone, and plasma renin activity (PRA)." | 9.06 | Postoperative hypertension after repair of coarctation of aorta in children: protective effect of propranolol? ( Balfe, JA; Balfe, JW; Barker, GA; Leenen, FH; Olley, PM; Pelech, AN, 1987) |
| "The effects of the nonselective beta blocker, propranolol, on coarctectomy-induced hypertension were evaluated relative to changes in cardiac function, sympathetic tone, and plasma renin activity (PRA)." | 5.06 | Postoperative hypertension after repair of coarctation of aorta in children: protective effect of propranolol? ( Balfe, JA; Balfe, JW; Barker, GA; Leenen, FH; Olley, PM; Pelech, AN, 1987) |
| "Oral propranolol is widely considered to be first-line therapy for complicated infantile hemangioma, but its use in patients with PHACE (posterior fossa malformations, hemangioma, arterial anomalies, cardiac defects, eye anomalies) syndrome has been debated owing to concerns that the cardiovascular effects of the drug may increase the risk for arterial ischemic stroke." | 3.96 | Evaluating the Safety of Oral Propranolol Therapy in Patients With PHACE Syndrome. ( Adams, D; Baselga, E; Chamlin, S; Drolet, BA; Frieden, IJ; Frommelt, P; Garzon, MC; Gupta, D; Hansen, LM; Horii, K; Klajn, J; Lauren, C; Maheshwari, M; Mancini, AJ; Mathes, E; McCuaig, CC; Newell, B; Nguyen, HL; Nopper, A; Olsen, GM; Powell, J; Puttgen, KB; Siegel, DH; Stefanko, NS; Tollefson, MM, 2020) |
| "Eight patients with aortic coarctation were studied at rest and during supine bicycle exercise before and after intravenous propranolol 0." | 3.65 | Exercise haemodynamics of coarctation of the aorta. Acute effects of propranolol. ( Cumming, GR; Mir, GH, 1970) |
| "Propranolol treatment was safe in our patients who did not show signs of perfusion changes." | 1.38 | Brain perfusion SPECT in patients with PHACES syndrome under propranolol treatment. ( Coya, J; Hernandez-Martin, S; Lopez-Fernandez, S; Lopez-Gutierrez, JC; Marin, D; Miguel, M; Ramírez, M; Tovar, JA, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (26.92) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 1 (3.85) | 29.6817 |
| 2010's | 12 (46.15) | 24.3611 |
| 2020's | 4 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Kleinman, EP | 1 |
| Blei, F | 1 |
| Adams, D | 2 |
| Greenberger, S | 1 |
| Lim, TH | 1 |
| Yap, E | 1 |
| Norhatizah, BS | 1 |
| Olsen, GM | 1 |
| Hansen, LM | 1 |
| Stefanko, NS | 1 |
| Mathes, E | 1 |
| Puttgen, KB | 1 |
| Tollefson, MM | 1 |
| Lauren, C | 1 |
| Mancini, AJ | 1 |
| McCuaig, CC | 1 |
| Frieden, IJ | 3 |
| Baselga, E | 2 |
| Chamlin, S | 1 |
| Gupta, D | 1 |
| Frommelt, P | 1 |
| Garzon, MC | 1 |
| Horii, K | 1 |
| Klajn, J | 1 |
| Maheshwari, M | 1 |
| Newell, B | 1 |
| Nguyen, HL | 1 |
| Nopper, A | 1 |
| Powell, J | 1 |
| Siegel, DH | 1 |
| Drolet, BA | 1 |
| Sazali, HB | 1 |
| Allen, NM | 1 |
| Murphy, A | 1 |
| Czechowicz, JA | 1 |
| Benjamin, T | 1 |
| Bly, RA | 1 |
| Ganti, SN | 1 |
| Balkin, DM | 1 |
| Perkins, JA | 1 |
| Rosbe, KW | 2 |
| Goldberg, V | 1 |
| Martinez, B | 1 |
| Cnop, K | 1 |
| Rohloff, P | 1 |
| Disse, SC | 1 |
| Zemlin, M | 1 |
| Mueller, C | 1 |
| Meyer, S | 1 |
| Bangiyev, JN | 1 |
| Gurgel, R | 1 |
| Vanderhooft, SL | 1 |
| Grimmer, JF | 1 |
| Solman, L | 1 |
| Glover, M | 1 |
| Beattie, PE | 1 |
| Buckley, H | 1 |
| Clark, S | 1 |
| Gach, JE | 1 |
| Giardini, A | 1 |
| Helbling, I | 1 |
| Hewitt, RJ | 1 |
| Laguda, B | 1 |
| Langan, SM | 1 |
| Martinez, AE | 1 |
| Murphy, R | 1 |
| Proudfoot, L | 1 |
| Ravenscroft, J | 1 |
| Shahidullah, H | 1 |
| Shaw, L | 1 |
| Syed, SB | 1 |
| Wells, L | 1 |
| Flohr, C | 1 |
| Rotter, A | 1 |
| Samorano, LP | 1 |
| Rivitti-Machado, MC | 1 |
| Oliveira, ZNP | 1 |
| Gontijo, B | 1 |
| Rokugo, Y | 1 |
| Ota, C | 1 |
| Kimura, M | 1 |
| Sasahara, Y | 1 |
| Bellaud, G | 1 |
| Puzenat, E | 1 |
| Billon-Grand, NC | 1 |
| Humbert, P | 1 |
| Aubin, F | 1 |
| Hoeger, PH | 1 |
| Harper, JI | 1 |
| Bonnet, D | 1 |
| Boon, LM | 1 |
| Ciofi Degli Atti, M | 1 |
| El Hachem, M | 1 |
| Oranje, AP | 1 |
| Rubin, AT | 1 |
| Weibel, L | 1 |
| Léauté-Labrèze, C | 1 |
| El Rassi, E | 1 |
| MacArthur, CJ | 1 |
| Hernandez-Martin, S | 1 |
| Lopez-Gutierrez, JC | 1 |
| Lopez-Fernandez, S | 1 |
| Ramírez, M | 1 |
| Miguel, M | 1 |
| Coya, J | 1 |
| Marin, D | 1 |
| Tovar, JA | 1 |
| Durr, ML | 1 |
| Meyer, AK | 1 |
| Huoh, KC | 1 |
| Höcht, C | 1 |
| Opezzo, JA | 1 |
| Taira, CA | 1 |
| Amaral, FT | 1 |
| Salgado, HC | 1 |
| Ostman-Smith, I | 1 |
| Will, RJ | 1 |
| Walker, OM | 1 |
| Traugott, RC | 1 |
| Treasure, RL | 1 |
| Zhivoderov, VM | 1 |
| Beliakov, KF | 1 |
| Knyzhov, VV | 1 |
| Leenen, FH | 1 |
| Balfe, JA | 1 |
| Pelech, AN | 1 |
| Barker, GA | 1 |
| Balfe, JW | 1 |
| Olley, PM | 1 |
| Gidding, SS | 1 |
| Rocchini, AP | 1 |
| Beekman, R | 1 |
| Szpunar, CA | 1 |
| Moorehead, C | 1 |
| Behrendt, D | 1 |
| Rosenthal, A | 1 |
| Cumming, GR | 1 |
| Mir, GH | 1 |
| Goodkind, MJ | 1 |
| Chidichimo, G | 1 |
| Marsocci, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Systemic Propranolol Treatment on the Physical Development of Paediatric Patients With Infantile Hemangiomas[NCT04651049] | 128 participants (Actual) | Observational | 2010-07-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for propranolol and Aortic Coarctation
| Article | Year |
|---|---|
Sirolimus for diffuse intestinal infantile hemangioma with PHACE features: systematic review.
Topics: Aortic Coarctation; Eye Abnormalities; Female; Hemangioma; Hemangioma, Capillary; Humans; Infant; Pr | 2023 |
PHACE syndrome: clinical manifestations, diagnostic criteria, and management.
Topics: Aortic Coarctation; Brain; Eye Abnormalities; Face; Facial Neoplasms; Hemangioma; Humans; Infant; Ma | 2018 |
Treatment of infantile haemangiomas: recommendations of a European expert group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aortic Coarctation; Cryotherapy; Diagnosis, Di | 2015 |
[Arterial hypertension following aortic coarctation correction].
Topics: Age Factors; Aortic Coarctation; Humans; Hypertension; Postoperative Complications; Propranolol | 1993 |
2 trials available for propranolol and Aortic Coarctation
| Article | Year |
|---|---|
Postoperative hypertension after repair of coarctation of aorta in children: protective effect of propranolol?
Topics: Adolescent; Aortic Coarctation; Blood Pressure; Catecholamines; Child; Child, Preschool; Clinical Tr | 1987 |
Therapeutic effect of propranolol on paradoxical hypertension after repair of coarctation of the aorta.
Topics: Aortic Coarctation; Blood Pressure; Child; Clinical Trials as Topic; Female; Heart Rate; Humans; Hyp | 1985 |
20 other studies available for propranolol and Aortic Coarctation
| Article | Year |
|---|---|
Facial segmental haemangioma with PHACE Syndrome successfully treated with oral propranolol.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aortic Coarctation; Disease Progression; Eye Abno | 2019 |
Evaluating the Safety of Oral Propranolol Therapy in Patients With PHACE Syndrome.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aortic Coarctation; Cohort Studies; Eye Abnormali | 2020 |
PHACE syndrome: importance of distinguishing infantile haemangioma from capillary malformation.
Topics: Adrenergic beta-Antagonists; Aortic Coarctation; Diagnosis, Differential; Eye Abnormalities; Female; | 2020 |
Airway Hemangiomas in PHACE Syndrome: A Multicenter Experience.
Topics: Aortic Coarctation; Eye Abnormalities; Female; Hemangioma; Humans; Infant; Infant, Newborn; Male; Ne | 2021 |
Use of propranolol in a remote region of rural Guatemala to treat a large facial infantile haemangioma.
Topics: Aortic Coarctation; Diagnosis, Differential; Eye Abnormalities; Face; Female; Guatemala; Hemangioma; | 2017 |
PHACE Syndrome-before and after Propranolol Therapy.
Topics: Adrenergic beta-Antagonists; Aortic Coarctation; Eye Abnormalities; Female; Humans; Infant; Neurocut | 2018 |
Reversible profound sensorineural hearing loss due to propranolol sensitive hemangioma in an infant with PHACE syndrome.
Topics: Adrenergic beta-Antagonists; Aortic Coarctation; Eye Abnormalities; Hearing Loss, Sensorineural; Hem | 2017 |
Oral propranolol in the treatment of proliferating infantile haemangiomas: British Society for Paediatric Dermatology consensus guidelines.
Topics: Administration, Oral; Aortic Coarctation; Clinical Decision-Making; Consensus; Delphi Technique; Der | 2018 |
Preoperative administration of propranolol reduced the surgical risks of PHACES syndrome in a 14-month-old girl.
Topics: Abnormalities, Multiple; Administration, Oral; Adrenergic beta-Antagonists; Airway Obstruction; Aort | 2019 |
PHACE syndrome, a series of six patients: clinical and morphological manifestations, propranolol efficacy, and safety.
Topics: Aortic Coarctation; Child; Child, Preschool; Eye Abnormalities; Facial Neoplasms; Female; Hemangioma | 2015 |
Propranolol-responsive cranial nerve palsies in a patient with PHACES syndrome.
Topics: Aortic Coarctation; Bell Palsy; Eye Abnormalities; Hemangioma; Humans; Infant; Neurocutaneous Syndro | 2015 |
Brain perfusion SPECT in patients with PHACES syndrome under propranolol treatment.
Topics: Adrenergic beta-Antagonists; Aortic Coarctation; Brain; Eye Abnormalities; Female; Humans; Infant; I | 2012 |
Airway hemangiomas in PHACE syndrome.
Topics: Aortic Coarctation; Bronchoscopy; Disease-Free Survival; Eye Abnormalities; Female; Follow-Up Studie | 2012 |
Anterior hypothalamic beta-adrenergic activity in the maintenance of hypertension in aortic coarctated rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anterior Hypothalamic Nucleus; Aorti | 2004 |
Reduction by oral propranolol treatment of left ventricular hypertrophy secondary to pressure-overload in the rat.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Aorta, Abdominal; Aortic Coarctation; Bo | 1995 |
Sodium nitroprusside and propranolol therapy for management of postcoarctectomy hypertension.
Topics: Administration, Oral; Adolescent; Adult; Aortic Coarctation; Blood Vessel Prosthesis; Child; Child, | 1978 |
[Functional heterogeneity of the myocardium and its significance in the processes of compensation of cardiac activity in different hemodynamic disorders].
Topics: Animals; Aorta, Thoracic; Aortic Coarctation; Benzilates; Choline; Coronary Circulation; Coronary Di | 1977 |
Exercise haemodynamics of coarctation of the aorta. Acute effects of propranolol.
Topics: Adolescent; Adult; Aorta; Aortic Coarctation; Blood Pressure; Brachial Artery; Cardiac Output; Child | 1970 |
Left ventricular myocardial contractile response to aortic constriction in the hyperthyroid guinea pig.
Topics: Animals; Aortic Coarctation; Blood Pressure; Guinea Pigs; Heart; Heart Rate; Hemodynamics; Hyperthyr | 1968 |
[Sinus tachycardia with high frequency after surgical correction of congenital malformations of the aortic arch; effect of beta-blocking agents. Observations on 2 cases].
Topics: Adolescent; Adult; Aorta; Aortic Coarctation; Arrhythmia, Sinus; Ductus Arteriosus, Patent; Female; | 1968 |