Page last updated: 2024-11-03

propranolol and Angina at Rest

propranolol has been researched along with Angina at Rest in 34 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"To characterize the potential of nifedipine in the therapy of unstable angina pectoris we implemented a blinded, randomly assigned, titrated schedule of conventional therapy (propranolol, if not contraindicated, and isosorbide dinitrate) or nifedipine for 14 days in 126 patients hospitalized in a coronary care unit for ischemic chest pain of less than 45 min duration."9.05Nifedipine and conventional therapy for unstable angina pectoris: a randomized, double-blind comparison. ( Morrison, J; Muller, JE; Pearle, DL; Rosner, B; Rude, RE; Schneider, JF; Serfas, DH; Sobel, BE; Stone, PH; Turi, ZG, 1984)
"The propranolol dose was increased every 6 hours by 50 to 100% to achieve a similar reduction in heart rate and blood pressure."6.66Safety and efficacy of esmolol for unstable angina pectoris. ( Littman, WJ; Pope, C; Scanlon, PJ; Wallis, DE, 1988)
"The propranolol group had a lower cumulative probability of experiencing recurrent resting angina than the placebo group (p = ."6.66Effect of the addition of propranolol to therapy with nifedipine for unstable angina pectoris: a randomized, double-blind, placebo-controlled trial. ( Achuff, SC; Baughman, KL; Brinker, JA; Chandra, NC; Gottlieb, SO; Mellits, ED; Ouyang, P; Shapiro, EP; Traill, TA; Weisfeldt, ML, 1986)
"To characterize the potential of nifedipine in the therapy of unstable angina pectoris we implemented a blinded, randomly assigned, titrated schedule of conventional therapy (propranolol, if not contraindicated, and isosorbide dinitrate) or nifedipine for 14 days in 126 patients hospitalized in a coronary care unit for ischemic chest pain of less than 45 min duration."5.05Nifedipine and conventional therapy for unstable angina pectoris: a randomized, double-blind comparison. ( Morrison, J; Muller, JE; Pearle, DL; Rosner, B; Rude, RE; Schneider, JF; Serfas, DH; Sobel, BE; Stone, PH; Turi, ZG, 1984)
" Although nifedipine is highly effective against vasospastic angina, its use in threatened myocardial infarction or severe unstable angina is not supported by recent studies, unless combined with a beta-blocker."4.77Calcium channel antagonists. Part II: Use and comparative properties of the three prototypical calcium antagonists in ischemic heart disease, including recommendations based on an analysis of 41 trials. ( Opie, LH, 1988)
"Altogether 75 patients (males aged 31 to 67 years) with unstable angina pectoris were subjected to transcutaneous pacing to measure the coronary reserve level before and after administration of obsidan (propranolol) in a dose of 40 mg."3.67[Evaluation of obzidan efficacy in patients with unstable stenocardia]. ( Gvatua, NA; Malinovskaia, IE; Pliska, AI; SHumakov, VA; Tashchuk, VK, 1989)
"A trend toward decreased recurrence of unstable angina was present in the surgery group at 1 year (six of 168 [3."2.67Quality of life after bypass surgery for unstable angina. 5-year follow-up results of a Veterans Affairs Cooperative Study. ( Booth, DC; DeMaria, AN; Deupree, RH; Hultgren, HN; Luchi, RJ; Scott, SM, 1991)
"The propranolol dose was increased every 6 hours by 50 to 100% to achieve a similar reduction in heart rate and blood pressure."2.66Safety and efficacy of esmolol for unstable angina pectoris. ( Littman, WJ; Pope, C; Scanlon, PJ; Wallis, DE, 1988)
"The propranolol group had a lower cumulative probability of experiencing recurrent resting angina than the placebo group (p = ."2.66Effect of the addition of propranolol to therapy with nifedipine for unstable angina pectoris: a randomized, double-blind, placebo-controlled trial. ( Achuff, SC; Baughman, KL; Brinker, JA; Chandra, NC; Gottlieb, SO; Mellits, ED; Ouyang, P; Shapiro, EP; Traill, TA; Weisfeldt, ML, 1986)
"Unstable angina is a common ischemic syndrome that is characterized by chest pain occurring at rest often with transient ischemic electrocardiographic changes."2.37Assessing the total ischemic burden in the management of unstable angina. A review. ( Gerstenblith, G; Gottlieb, SO, 1986)
"Propranolol was the only intervention that produced a significant decrease in diastolic pulmonary artery pressure (16 +/- 5 to 11 +/- 3 mmHg, P < 0."1.33Different effects of propranolol, phenylephrine, and saline volume loading on catecholamine-induced left ventricular outflow tract obstruction in acute coronary syndrome. ( Hamasaki, S; Minagoe, S; Ohba, I; Otsuji, Y; Shiki, K; Tei, C, 2006)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199024 (70.59)18.7374
1990's9 (26.47)18.2507
2000's1 (2.94)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ohba, I1
Otsuji, Y1
Shiki, K1
Hamasaki, S1
Minagoe, S1
Tei, C1
Andre-Fouet, X1
Usdin, JP1
Gayet, C1
Wilner, C1
Thizy, JF1
Viallet, M1
Apoil, E1
Vernant, P1
Pont, M1
Muller, JE1
Turi, ZG1
Pearle, DL1
Schneider, JF1
Serfas, DH1
Morrison, J1
Stone, PH1
Rude, RE1
Rosner, B1
Sobel, BE1
Rankin, JS1
Newton, JR1
Califf, RM1
Jones, RH1
Wechsler, AS1
Oldham, HN1
Wolfe, WG1
Lowe, JE1
Hugenholtz, PG1
Michels, R1
Serruys, PW1
Simoons, ML1
Capucci, A2
Bracchetti, D2
Carini, G2
Di Ciò, G2
Maresta, A2
Magnani, B2
Forfang, K1
Gullestad, L1
Cleophas, TJ2
van 't Leven, M2
Kauw, FH2
Remmert, HP2
Kuijper, A2
Zwinderman, K2
Nozawa, T1
Inoue, H1
Morelli, S1
Gurgo, AM1
Martocchia, A1
Falaschi, P1
Ramires, JA1
Mansur, Ade P1
César, LA1
Piegas, LS1
Timerman, A1
Nonohay, NC1
Azevedo, AR1
Vaz, R1
da Luz, PL1
Kubyshkin, VF1
Koryt'ko, IN1
Booth, DC1
Deupree, RH1
Hultgren, HN1
DeMaria, AN1
Scott, SM1
Luchi, RJ1
Shibleva, VV1
Rubanovich, AI1
Karpov, IuA2
Podinovskaia, IaA1
Ruda, MIa1
De Servi, S1
Berzuini, C1
Poma, E1
Ferrario, M1
Ghio, S1
Sciré, A1
Cioffi, P1
Ardissino, D1
Montemartini, C1
Specchia, G1
Brunke, W1
Anders, G1
Müller, JH1
Abet, U1
Bodammer, M1
Gvatua, NA1
SHumakov, VA1
Tashchuk, VK2
Malinovskaia, IE1
Pliska, AI1
Gottlieb, SO3
Gerstenblith, G2
Wallis, DE1
Pope, C1
Littman, WJ1
Scanlon, PJ1
Opie, LH1
Sclarovsky, S1
Bassevich, R1
Klainman, E1
Rechavia, E1
Sagie, A1
Agmon, J1
Pustovoĭt, GD1
Kukharchuk, VV1
Kutsenko, AI1
Noeva, EA1
Zaruba, AIu1
Weisfeldt, ML1
Ouyang, P1
Achuff, SC1
Baughman, KL1
Traill, TA1
Brinker, JA1
Shapiro, EP1
Chandra, NC1
Mellits, ED1
Nicolas, G1
Witchitz, S1
Beaufils, P1
Bory, M1
Bourdarias, JP1
Gilgenkrantz, JM1
Guize, L1
Kolsky, H1
Letac, B1
Sellier, P1
Orlov, VA1
Iakunin, GA2
Khishtovani, AI2
Dmitriev, AA1
Kormer, AIa1
von Arnim, T1
Reuschel-Janetschek, E1
Werdan, K1
Erdmann, E1
Autenrieth, G1
Théroux, P1
Taeymans, Y1
Morissette, D1
Bosch, X1
Pelletier, GB1
Waters, DD1

Reviews

4 reviews available for propranolol and Angina at Rest

ArticleYear
[Treatment with beta-blockers in patients with acute coronary syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:10

    Topics: Acute Disease; Adrenergic beta-Antagonists; Angina, Unstable; Atenolol; Clinical Trials as Topic; Co

1998
Thyrotoxicosis, unstable angina and normal coronary angiogram.
    Giornale italiano di cardiologia, 1999, Volume: 29, Issue:11

    Topics: Angina, Unstable; Anti-Arrhythmia Agents; Chest Pain; Combined Modality Therapy; Coronary Angiograph

1999
Assessing the total ischemic burden in the management of unstable angina. A review.
    The American journal of medicine, 1986, Oct-20, Volume: 81, Issue:4A

    Topics: Adrenergic beta-Antagonists; Angina, Unstable; Coronary Artery Bypass; Coronary Disease; Drug Therap

1986
Calcium channel antagonists. Part II: Use and comparative properties of the three prototypical calcium antagonists in ischemic heart disease, including recommendations based on an analysis of 41 trials.
    Cardiovascular drugs and therapy, 1988, Volume: 1, Issue:5

    Topics: Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Thera

1988

Trials

12 trials available for propranolol and Angina at Rest

ArticleYear
Comparison of short-term efficacy of diltiazem and propranolol in unstable angina at rest--a randomized trial in 70 patients.
    European heart journal, 1983, Volume: 4, Issue:10

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Benzazepines; Clinical Trials as Topic; Coronary Ang

1983
Nifedipine and conventional therapy for unstable angina pectoris: a randomized, double-blind comparison.
    Circulation, 1984, Volume: 69, Issue:4

    Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ma

1984
[Double-blind comparison of verapamil and propranolol in the therapy of unstable angina].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:5

    Topics: Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Female; Huma

1982
Celiprolol vs propranolol in unstable angina pectoris: a double-blind, randomized, parallel-group study.
    Angiology, 1995, Volume: 46, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Celiprolol; Chi-Square Distribution; Double-Blind

1995
Celiprolol and propranolol for unstable angina pectoris.
    Clinical pharmacology and therapeutics, 1995, Volume: 57, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Angina, Unstable; Celiprolol; Coronary Disease

1995
[Unstable angina: comparison of the effects of diltiazem and propranolol].
    Arquivos brasileiros de cardiologia, 1992, Volume: 58, Issue:1

    Topics: Angina, Unstable; Cineangiography; Diltiazem; Double-Blind Method; Electrocardiography; Female; Huma

1992
Quality of life after bypass surgery for unstable angina. 5-year follow-up results of a Veterans Affairs Cooperative Study.
    Circulation, 1991, Volume: 83, Issue:1

    Topics: Angina, Unstable; Coronary Artery Bypass; Exercise Test; Follow-Up Studies; Humans; Male; Middle Age

1991
Therapeutic choices in unstable angina.
    The American journal of medicine, 1986, Apr-30, Volume: 80, Issue:4C

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon; Anticoagulants

1986
Safety and efficacy of esmolol for unstable angina pectoris.
    The American journal of cardiology, 1988, Nov-15, Volume: 62, Issue:16

    Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Angina, Unstable; Blood Pressure; Female; Heart

1988
Effect of the addition of propranolol to therapy with nifedipine for unstable angina pectoris: a randomized, double-blind, placebo-controlled trial.
    Circulation, 1986, Volume: 73, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Femal

1986
[Treatment of unstable angina. A randomized double-blind study of propranolol, diltiazem and molsidomine].
    Annales de cardiologie et d'angeiologie, 1986, Oct-30, Volume: 35, Issue:8

    Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Female;

1986
A randomized study comparing propranolol and diltiazem in the treatment of unstable angina.
    Journal of the American College of Cardiology, 1985, Volume: 5, Issue:3

    Topics: Aged; Angina Pectoris; Angina, Unstable; Benzazepines; Clinical Trials as Topic; Coronary Disease; D

1985

Other Studies

18 other studies available for propranolol and Angina at Rest

ArticleYear
Different effects of propranolol, phenylephrine, and saline volume loading on catecholamine-induced left ventricular outflow tract obstruction in acute coronary syndrome.
    International heart journal, 2006, Volume: 47, Issue:2

    Topics: Adrenergic beta-Antagonists; Angina, Unstable; Animals; Coronary Artery Disease; Dobutamine; Dogs; H

2006
A 66-year-old man has an unexpected low cardiac output syndrome during repeat myocardial revascularization.
    Journal of cardiothoracic anesthesia, 1988, Volume: 2, Issue:3

    Topics: Aged; Angina, Unstable; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Output, Low; Cardiotonic Age

1988
Clinical characteristics and current management of medically refractory unstable angina.
    Annals of surgery, 1984, Volume: 200, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Blood Pressure; Coronary Artery Bypass; Female; Foll

1984
Treatment of unstable angina with emphasis on calcium antagonists.
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:11

    Topics: Angina Pectoris; Angina, Unstable; Anticoagulants; Coronary Circulation; Coronary Disease; Electroca

1984
[Double-blind comparison between verapamil and propranolol in the therapy of unstable angina].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:5

    Topics: Aged; Angina Pectoris; Angina, Unstable; Double-Blind Method; Drug Evaluation; Female; Humans; Male;

1982
[Drug therapy of angina pectoris. Are the possibilities exploited well enough?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1995, Aug-10, Volume: 115, Issue:18

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Angina, Unstable; Female; Humans; Isosorb

1995
[Lipid peroxidation in patients with unstable stenocardia treated with adrenergic beta blockers].
    Sovetskaia meditsina, 1991, Issue:1

    Topics: Angina, Unstable; Erythrocyte Membrane; Humans; Lipid Peroxidation; Pindolol; Propranolol

1991
[Immediate and late prognosis in patients with unstable angina under medical treatment].
    Kardiologiia, 1990, Volume: 30, Issue:10

    Topics: Adult; Aged; Angina, Unstable; Calcium Channel Blockers; Death, Sudden; Electrocardiography; Female;

1990
Long-term survival and risk stratification in patients with angina at rest undergoing medical treatment.
    International journal of cardiology, 1989, Volume: 22, Issue:1

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Coronary Angiography; Electrocardiography; Female; H

1989
[The significance of a staged diagnostic-therapeutic program for the disease course in patients following unstable angina pectoris during a follow-up period of 3 1/2 years].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1989, Jun-01, Volume: 44, Issue:11

    Topics: Angina Pectoris; Angina, Unstable; Angioplasty, Balloon; Combined Modality Therapy; Coronary Disease

1989
[Evaluation of obzidan efficacy in patients with unstable stenocardia].
    Terapevticheskii arkhiv, 1989, Volume: 61, Issue:8

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Cardiac Pacing, Artificial; Coronary Disease; Drug E

1989
Unstable angina with tachycardia: clinical and therapeutic implications.
    American heart journal, 1988, Volume: 116, Issue:5 Pt 1

    Topics: Aged; Amiodarone; Angina Pectoris; Angina, Unstable; Electrocardiography; Female; Heart Rate; Humans

1988
[Use of decimeter microwaves and drugs in patients with unstable stenocardia].
    Vrachebnoe delo, 1987, Issue:9

    Topics: Angina Pectoris; Angina, Unstable; Combined Modality Therapy; Delayed-Action Preparations; Drug Ther

1987
[Clinical effectiveness of plasmapheresis in patients with unstable stenocardia refractory to drug therapy].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1987, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Angina Pectoris; Angina, Unstable; Humans; Middle Aged; Nitrates; Plasmaphe

1987
[Effect of various drugs on rheological properties of the blood and hemostasis in patients with unstable stenocardia].
    Klinicheskaia meditsina, 1987, Volume: 65, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Aspirin; Blood Viscosity; Female; Hemostasis; Humans

1987
[Effect of hemosorption and the separate and combined use of obsidan, trental and colpharit on rheological and hemostatic properties of the blood in patients with unstable stenocardia].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:5

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Aspirin; Blood Viscosity; Combined Modality Therapy;

1986
[Conservative therapy of unstable angina pectoris].
    Fortschritte der Medizin, 1986, Jul-10, Volume: 104, Issue:26

    Topics: Angina Pectoris; Angina, Unstable; Drug Therapy, Combination; Humans; Isosorbide Dinitrate; Nifedipi

1986
[Intracardiac hemodynamics in unstable stenocardia patients performing a test with transesophageal frequency-increasing cardiac stimulation].
    Vrachebnoe delo, 1986, Issue:9

    Topics: Angina Pectoris; Angina, Unstable; Cardiac Pacing, Artificial; Drug Evaluation; Echocardiography; El

1986