Page last updated: 2024-11-03

propranolol and Aneurysm, Aortic

propranolol has been researched along with Aneurysm, Aortic in 48 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"Twenty-five patients, 16 men and 9 women, 5-59 years of age with the Marfan syndrome and cardiac complications were started on propranolol over a 6-year period."7.65Prophylactiv use of propranolol in the Marfan syndrome to prevent aortic dissection. ( McKusick, VA; Ose, L, 1977)
" Early work with experimental animal models of aortic aneurysms showed that Propranolol has a protective effect on extension and rupture of these aneurysms."3.69[Medical treatment of aortic aneurysms using beta-blockers]. ( Chakkour, K; Gouny, P; Nussaume, O; Vayssairat, M, 1995)
"Propranolol prevents or delays the formation of aortic aneurysms in both the lathyritic turkey and the Blotchy mouse models."3.67Propranolol stimulates the crosslinking of matrix components in skin from the aneurysm-prone blotchy mouse. ( Brophy, CM; Tilson, JE; Tilson, MD, 1989)
"Propranolol has been reported to prevent aortic aneurysms in the beta-aminoproprionitrile-fed broad-breasted white turkey model."3.67Propranolol delays the formation of aneurysms in the male blotchy mouse. ( Brophy, C; Tilson, JE; Tilson, MD, 1988)
"A regimen consisting of chlorthalidone, hydralazine and propranolol would be useful in some hypertensive patients with coronary artery disease or aortic dissection if it could be shown that reflex cardiac stimulation induced by hydralazine is completely neutralized by propranolol."3.66Echocardiographic assessment of the effect of an antihypertensive regimen on left ventricular performance. ( Belasco, RN; Moyer, JP; Pittman, AW; Woods, JW, 1979)
"Twenty-five patients, 16 men and 9 women, 5-59 years of age with the Marfan syndrome and cardiac complications were started on propranolol over a 6-year period."3.65Prophylactiv use of propranolol in the Marfan syndrome to prevent aortic dissection. ( McKusick, VA; Ose, L, 1977)
"The 3 patients in group I with aortic dissection had an aortic root diameter greater than or equal to 5."1.27Anuloaortic ectasia: a clinical and echocardiographic study. ( Fox, R; Kotler, MN; Mintz, GS; Panidis, IP; Ren, JF; Ross, J, 1984)
"When controlled hypotension is added to myocardial depression, aortic dissection is inhibited completely."1.25Control of acute aortic dissection. ( Carney, WI; Cleveland, RJ; Rheinlander, HF, 1975)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199040 (83.33)18.7374
1990's5 (10.42)18.2507
2000's3 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bayles, J1
Habashi, JP1
Judge, DP1
Holm, TM1
Cohn, RD1
Loeys, BL1
Cooper, TK1
Myers, L1
Klein, EC1
Liu, G1
Calvi, C1
Podowski, M1
Neptune, ER1
Halushka, MK1
Bedja, D1
Gabrielson, K1
Rifkin, DB1
Carta, L1
Ramirez, F1
Huso, DL1
Dietz, HC1
Peña, JJ1
Marqués, JI1
Mateo, E1
Llagunes, J1
Aguar, F1
de Andrés, J1
Fox, R1
Ren, JF1
Panidis, IP1
Kotler, MN1
Mintz, GS1
Ross, J1
Simpson, CF2
Boucek, RJ1
Hashimoto, M1
Goda, T1
Aoki, H1
Takeda, T1
Moriyama, H1
Wheat, MW3
Lieberman, A1
Kronzon, I1
Colvin, S1
Lowenstein, J1
Lieberman, I1
Goldman, L1
Moursi, MM1
Beebe, HG1
Messina, LM1
Welling, TH1
Stanley, JC1
Shores, J1
Berger, KR1
Murphy, EA1
Pyeritz, RE1
Chakkour, K1
Gouny, P1
Nussaume, O1
Vayssairat, M1
Ose, L1
McKusick, VA2
Moran, JF1
Derkac, WM1
Conkle, DM1
Moyer, JP1
Pittman, AW1
Belasco, RN1
Woods, JW1
Roan, P1
Parish, S1
Buja, LM1
Estrera, A1
Mills, L1
Atkins, J1
Willerson, J1
Wood, AJ1
Shand, DG1
Parker, FB1
Neville, JF1
Hanson, EL1
Mohiuddin, S1
Webb, WR1
Carney, WI1
Rheinlander, HF1
Cleveland, RJ1
Deeg, P1
Schneider, KW1
Jesse, R1
Palmer, RF4
Lasseter, KC1
Tilson, MD4
Walker, WA1
Pate, JW1
Brophy, CM1
Tilson, JE2
Leach, SD1
Toole, AL1
Stern, H1
DeNatale, RW1
Grajek, S1
Pyda, M1
Kmiecik-Kaźmierczak, E1
Brocki, Z1
Nikisch, B1
Brophy, C1
Cola, LM1
Lavin, JP1
Lawrence, T1
Frankl, WS1
Strong, WW1
Moggio, RA1
Stansel, HC1
Dalen, JE1
Alpert, JS1
Cohn, LH1
Black, H1
Collins, JJ1
Heinrich, F3
Fernandes, M1
Kim, KE1
Moyer, JH1
Dollery, CT1
George, C1
Castan, R1
Conn, RD1
McFarland, J1
Willerson, JT1
Dinsmore, RE1
Austen, WG1
Buckley, MJ1
Sanders, CA1
DeSanctis, RW1
Rothlin, ME1
Meier, WE1
Lindsay, J2
Hurst, JW2
Halpern, BL1
Char, F1
Murdoch, JL1
Horton, WB1
Attar, S1
Fardin, R1
Ayella, R1
McLaughlin, JS1
Kling, JM1
Rosenblum, R1
Delman, AJ1
Harris, PD1
Malm, JR1
Kaiser, G1
Bowman, FO1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Losartan vs. Nebivolol vs. the Association of Both on the Progression of Aortic Root Dilation in Marfan Syndrome (MFS) With FBN1 Gene Mutations.[NCT00683124]Phase 3291 participants (Anticipated)Interventional2008-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for propranolol and Aneurysm, Aortic

ArticleYear
Beta-adrenergic receptor blocking drugs.
    The Medical clinics of North America, 1973, Volume: 57, Issue:4

    Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Aortic Aneurysm; Aortic Valve; Arrhythmias

1973
Hypertensive emergencies.
    Pennsylvania medicine, 1974, Volume: 77, Issue:7

    Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Antihypertensive Agents; Aortic Aneurysm; Blood Volume

1974
Propranolol--ten years from introduction.
    Cardiovascular clinics, 1974, Volume: 6, Issue:2

    Topics: Angina Pectoris; Antihypertensive Agents; Anxiety; Aortic Aneurysm; Arrhythmias, Cardiac; Cardiomyop

1974
Management of impending rupture of the aorta with dissection.
    Advances in internal medicine, 1971, Volume: 17

    Topics: Aminopropionitrile; Animals; Aortic Aneurysm; Aortic Rupture; Blood Pressure; Electrocardiography; F

1971

Trials

2 trials available for propranolol and Aneurysm, Aortic

ArticleYear
Progression of aortic dilatation and the benefit of long-term beta-adrenergic blockade in Marfan's syndrome.
    The New England journal of medicine, 1994, May-12, Volume: 330, Issue:19

    Topics: Adolescent; Adult; Aorta; Aortic Aneurysm; Aortic Dissection; Aortic Valve Insufficiency; Dilatation

1994
Propranolol versus placebo for small abdominal aortic aneurysms.
    Journal of vascular surgery, 1992, Volume: 15, Issue:5

    Topics: Aorta, Abdominal; Aortic Aneurysm; Clinical Trials as Topic; Humans; Propranolol; Research Design

1992

Other Studies

42 other studies available for propranolol and Aneurysm, Aortic

ArticleYear
Sounding the alarm. If undetected, Marfan syndrome can be a silent killer.
    The Journal of the Arkansas Medical Society, 2002, Volume: 99, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aortic Aneurysm; Aortic Dissection; Chest Pain; Female; Humans;

2002
Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.
    Science (New York, N.Y.), 2006, Apr-07, Volume: 312, Issue:5770

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies; Aorta; Ao

2006
[Perioperative management of a ruptured sinus of Valsalva aneurysm].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:3

    Topics: Anesthesia, General; Antithyroid Agents; Aortic Aneurysm; Aortic Rupture; Atrial Premature Complexes

2008
Anuloaortic ectasia: a clinical and echocardiographic study.
    The American journal of cardiology, 1984, Jul-01, Volume: 54, Issue:1

    Topics: Adult; Aged; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Dilatation, Pathologic; Echocardio

1984
The B-aminopropionitrile-fed turkey: a model for detecting potential drug action on arterial tissue.
    Cardiovascular research, 1983, Volume: 17, Issue:1

    Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Diseases; Disease Models, Ani

1983
[Surgical treatment of experimental dissecting aneurysm].
    Rinsho kyobu geka = Japanese annals of thoracic surgery, 1981, Volume: 1, Issue:2

    Topics: Animals; Aortic Aneurysm; Aortic Dissection; Dogs; Prognosis; Propranolol; Trimethaphan

1981
Current status of medical therapy of acute dissecting aneurysms of the aorta.
    World journal of surgery, 1980, Volume: 4, Issue:5

    Topics: Acute Disease; Aorta; Aortic Aneurysm; Aortic Dissection; Follow-Up Studies; Humans; Methyldopa; Nit

1980
Propranolol: an unrecognized cause of central nervous system dysfunction in patients undergoing cardiopulmonary bypass.
    The Annals of thoracic surgery, 1980, Volume: 29, Issue:4

    Topics: Aortic Aneurysm; Aortic Dissection; Cardiopulmonary Bypass; Humans; Hypertension; Male; Middle Aged;

1980
Noncardiac surgery in patients receiving propranolol. Case reports and recommended approach.
    Archives of internal medicine, 1981, Volume: 141, Issue:2

    Topics: Anesthesia, General; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm; Cardiovascular Diseases; Hu

1981
Inhibition of aortic aneurysm development in blotchy mice by beta adrenergic blockade independent of altered lysyl oxidase activity.
    Journal of vascular surgery, 1995, Volume: 21, Issue:5

    Topics: Animals; Aorta, Thoracic; Aortic Aneurysm; Atenolol; Blood Pressure; Heart Rate; Male; Mice; Mice, M

1995
[Medical treatment of aortic aneurysms using beta-blockers].
    Journal des maladies vasculaires, 1995, Volume: 20, Issue:4

    Topics: Adrenergic beta-Antagonists; Aortic Aneurysm; Humans; Propranolol

1995
Prophylactiv use of propranolol in the Marfan syndrome to prevent aortic dissection.
    Birth defects original article series, 1977, Volume: 13, Issue:3C

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aorta, Thoracic; Aortic Aneurysm; Child, Preschool;

1977
Pharmacologic control of acute aortic dissection in hypertensive dogs.
    Surgical forum, 1978, Volume: 29

    Topics: Animals; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Dogs; Drug Therapy, Combination; Ferric

1978
Echocardiographic assessment of the effect of an antihypertensive regimen on left ventricular performance.
    The American journal of cardiology, 1979, Volume: 43, Issue:3

    Topics: Adult; Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Chlorthalidone; Coronary Disease

1979
Dissecting aortic aneurysm involving a right-sided aortic arch.
    The American journal of cardiology, 1979, Volume: 44, Issue:2

    Topics: Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Autopsy; Female; Humans; Middle Aged; Propranol

1979
Propranolol in the treatment of cardiovascular disease.
    Southern medical journal, 1978, Volume: 71, Issue:5

    Topics: Angina Pectoris; Aortic Aneurysm; Aortic Dissection; Arrhythmias, Cardiac; Cardiomyopathies; Cardiov

1978
Management of acute aortic dissection.
    The Annals of thoracic surgery, 1975, Volume: 19, Issue:4

    Topics: Antihypertensive Agents; Aortic Aneurysm; Aortography; Blood Pressure Determination; Central Venous

1975
Control of acute aortic dissection.
    Surgery, 1975, Volume: 78, Issue:1

    Topics: Animals; Aorta; Aortic Aneurysm; Blood Pressure; Depression, Chemical; Disease Models, Animal; Dogs;

1975
[Dissecting, nondissecting aortic aneurysm: surgical or conservative treatment].
    Medizinische Monatsschrift, 1975, Volume: 29, Issue:7

    Topics: Aged; Aortic Aneurysm; Guanethidine; Humans; Male; Methyldopa; Middle Aged; Propranolol; Reserpine

1975
Letter: Nitroprusside and aortic dissecting aneurysm.
    The New England journal of medicine, 1976, Jun-17, Volume: 294, Issue:25

    Topics: Animals; Aortic Aneurysm; Dogs; Drug Therapy, Combination; Ferricyanides; Humans; Nitroprusside; Pro

1976
Medical management of acute traumatic rupture of the aorta.
    The Annals of thoracic surgery, 1990, Volume: 50, Issue:6

    Topics: Abdominal Injuries; Acute Disease; Adult; Aortic Aneurysm; Aortic Rupture; Cardiac Catheterization;

1990
Propranolol stimulates the crosslinking of matrix components in skin from the aneurysm-prone blotchy mouse.
    The Journal of surgical research, 1989, Volume: 46, Issue:4

    Topics: Animals; Aortic Aneurysm; Collagen; Connective Tissue; Elastin; Male; Mice; Mice, Mutant Strains; Pr

1989
Effect of beta-adrenergic blockade on the growth rate of abdominal aortic aneurysms.
    Archives of surgery (Chicago, Ill. : 1960), 1988, Volume: 123, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Aorta, Abdominal; Aortic Aneurysm; Atenolol; Female; Humans; Male

1988
[3 cases of conservatively treated aortic dissecting aneurysm in patients with arterial hypertension. Results of a long-term ambulatory observation].
    Polskie Archiwum Medycyny Wewnetrznej, 1988, Volume: 80, Issue:6

    Topics: Aged; Ambulatory Care; Antihypertensive Agents; Aorta, Abdominal; Aortic Aneurysm; Aortic Dissection

1988
Propranolol delays the formation of aneurysms in the male blotchy mouse.
    The Journal of surgical research, 1988, Volume: 44, Issue:6

    Topics: Animals; Aorta; Aortic Aneurysm; Male; Mice; Mice, Mutant Strains; Propranolol

1988
Pregnancy complicated by Marfan's syndrome with aortic arch dissection, subsequent aortic arch replacement and triple coronary artery bypass grafts.
    The Journal of reproductive medicine, 1985, Volume: 30, Issue:9

    Topics: Adult; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Cesarean Section; Coronary Artery Bypass

1985
Acute aortic dissection. Twelve-year medical and surgical experience.
    The Journal of thoracic and cardiovascular surgery, 1974, Volume: 68, Issue:5

    Topics: Adult; Aged; Antihypertensive Agents; Aorta, Thoracic; Aortic Aneurysm; Aortic Diseases; Connecticut

1974
Dissection of the thoracic aorta. Medical or surgical therapy?
    The American journal of cardiology, 1974, Volume: 34, Issue:7

    Topics: Adult; Aged; Aorta, Thoracic; Aortic Aneurysm; Aortic Valve Insufficiency; Autonomic Agents; Blood P

1974
[Problems in the establishment of indications for treatment of aortic (thoracic and abdominal) aneurysms, from a medical viewpoint (author's transl)].
    Langenbecks Archiv fur Chirurgie, 1974, Volume: 337

    Topics: Aged; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm; Aortic Rupture; Guanethidine; Humans; Hypo

1974
[Clinical use of propranolol].
    L'union medicale du Canada, 1974, Volume: 103, Issue:8

    Topics: Alcoholism; Angina Pectoris; Aortic Aneurysm; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flut

1974
Clinical usefulness of beta-adrenergic blocking agents.
    Postgraduate medicine, 1974, Volume: 55, Issue:2

    Topics: Administration, Oral; Angina Pectoris; Aortic Aneurysm; Arrhythmias, Cardiac; Cardiomyopathy, Hypert

1974
The medical treatment of dissecting aortic aneurysms.
    The New England journal of medicine, 1972, Jan-20, Volume: 286, Issue:3

    Topics: Acute Disease; Adult; Aged; Aortic Aneurysm; Aortic Rupture; Aortography; Chronic Disease; Female; F

1972
[Dissecting aortic aneurysm].
    Therapeutische Umschau. Revue therapeutique, 1972, Volume: 29, Issue:2

    Topics: Aortic Aneurysm; Aortic Rupture; Guanethidine; Humans; Propranolol; Reserpine; Trimethaphan

1972
[Therapy of dissecting aneurysm of the aorta].
    Minerva medica, 1972, Apr-25, Volume: 63, Issue:31

    Topics: Aortic Aneurysm; Aortography; Guanethidine; Humans; Propranolol; Trimethaphan

1972
Management of dissecting aneurysm of the aorta.
    Postgraduate medicine, 1972, Volume: 51, Issue:4

    Topics: Aorta, Thoracic; Aortic Aneurysm; Guanethidine; Humans; Hypertension; Methyldopa; Propranolol; Trime

1972
Dissecting aneurysm of the aorta.
    JAMA, 1971, Sep-13, Volume: 217, Issue:11

    Topics: Acute Disease; Administration, Oral; Aortic Aneurysm; Aortic Rupture; Aortography; Guanethidine; Hum

1971
A prospectus on the prevention of aortic rupture in the Marfan syndrome with data on survivorship without treatment.
    The Johns Hopkins medical journal, 1971, Volume: 129, Issue:3

    Topics: Adolescent; Adult; Aortic Aneurysm; Aortic Rupture; Child; Electrocardiography; Female; Follow-Up St

1971
Medical vs surgical treatment of acute dissecting aneurysms.
    Archives of surgery (Chicago, Ill. : 1960), 1971, Volume: 103, Issue:5

    Topics: Acute Disease; Acute Kidney Injury; Adult; Aged; Aortic Aneurysm; Aortic Rupture; Aortography; Blood

1971
Beta-aminopropionitrile-induced dissecting aneurysms of turkeys: treatment with propranolol.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:1

    Topics: Aminopropionitrile; Animals; Aorta; Aorta, Abdominal; Aortic Aneurysm; Aortic Rupture; Blood Pressur

1970
Propranolol in the treatment of hyperkinetic heart syndrome, idiopathic hypertrophic subaortic stenosis, and systemic hypertension.
    American heart journal, 1970, Volume: 79, Issue:1

    Topics: Aortic Aneurysm; Cardiomyopathy, Hypertrophic; Coronary Vessels; Heart Diseases; Humans; Hypertensio

1970
[Therapy of aneurysma dissecans aortae].
    Deutsche medizinische Wochenschrift (1946), 1971, Apr-09, Volume: 96, Issue:15

    Topics: Antihypertensive Agents; Aorta; Aortic Aneurysm; Aortic Rupture; Aortic Valve; Aortography; Diuretic

1971
Acute dissecting aneurysms of the aorta. Treatment of results in 64 patients.
    The Journal of thoracic and cardiovascular surgery, 1969, Volume: 58, Issue:3

    Topics: Acute Disease; Adult; Aged; Aortic Aneurysm; Aortic Valve Insufficiency; Female; Follow-Up Studies;

1969