propranolol has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bozik, ME | 1 |
| Mitsumoto, H | 1 |
| Brooks, BR | 1 |
| Rudnicki, SA | 1 |
| Moore, DH | 1 |
| Zhang, B | 1 |
| Ludolph, A | 1 |
| Cudkowicz, ME | 1 |
| van den Berg, LH | 1 |
| Mather, J | 1 |
| Petzinger, T | 1 |
| Archibald, D | 1 |
| Il'ina, NA | 1 |
| Poliakova, NF | 1 |
| Khokhlov, AP | 1 |
1 trial available for propranolol and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
A post hoc analysis of subgroup outcomes and creatinine in the phase III clinical trial (EMPOWER) of dexpramipexole in ALS.
Topics: Adrenergic beta-Antagonists; Amyotrophic Lateral Sclerosis; Clinical Trials, Phase II as Topic; Crea | 2014 |
1 other study available for propranolol and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
[Pathogenesis of creatinuria and aminoaciduria in neuromuscular diseases].
Topics: Adolescent; Adult; Amino Acids; Amyotrophic Lateral Sclerosis; Caffeine; Child; Child, Preschool; Cr | 1977 |