Page last updated: 2024-11-03

propranolol and Alcohol Drinking

propranolol has been researched along with Alcohol Drinking in 34 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.

Research Excerpts

ExcerptRelevanceReference
"Alcohol drinking following propranolol treatment was variable, but the combination of propranolol + prazosin consistently suppressed alcohol drinking during both alcohol withdrawal and following prolonged imposed abstinence, and the combination of these 2 drugs was more effective than was treatment with either drug alone."7.80Combining the α1 -adrenergic receptor antagonist, prazosin, with the β-adrenergic receptor antagonist, propranolol, reduces alcohol drinking more effectively than either drug alone. ( Beckwith, LE; Froehlich, JC; Kincaid, CL; Rasmussen, DD, 2014)
"Alcohol drinking following propranolol treatment was variable, but the combination of propranolol + prazosin consistently suppressed alcohol drinking during both alcohol withdrawal and following prolonged imposed abstinence, and the combination of these 2 drugs was more effective than was treatment with either drug alone."3.80Combining the α1 -adrenergic receptor antagonist, prazosin, with the β-adrenergic receptor antagonist, propranolol, reduces alcohol drinking more effectively than either drug alone. ( Beckwith, LE; Froehlich, JC; Kincaid, CL; Rasmussen, DD, 2014)
"Nonselective β-blockers (NSBBs), such as propranolol, reportedly exert a pleiotropic effect in liver cirrhosis."3.78Is there any vindication for low dose nonselective β-blocker medication in patients with liver cirrhosis? ( Cho, YK; Chon, CU; Jeon, WK; Kim, BI; Kim, HJ; Kim, TW; Park, DI; Park, JH; Sohn, CI; Won, HS, 2012)
"Profound hypothermia lowers the ethanol disappearance rate when both S-propranolol and ethanol are given."3.72Interaction between S-propranolol and ethanol in mice selectively bred for ethanol sensitivity: the inbred short- and long-sleep mice. ( Bludeau, P; Deitrich, RA, 2003)
" The other cases published are: 1) 10 cases with oxprenolol (including 5 cases of coma and 4 deaths), 2) 9 cases with acebutolol (2 deaths) including 5 with studies of the kinetics of the product (1 personal case), 3) 7 cases with pindolol (no bradycardia, good prognosis), 4) 6 cases (1 personal) with metoprolol (4 cases of massive ingestion with 1 death), 5) 3 cases with alprenolol (1 death), 6) 4 cases with sotalol (2 cases of turned apex, 1 death), 7) 1 case with atenolol."3.66[Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases]. ( Auzépy, P; Boukara, N; Giudicelli, JF; Richard, C, 1983)
"Propranolol is a widely used drug for prophylaxis of variceal bleeding in patients with cirrhosis, but not all patients show an adequate clinical response."2.72Functional status of beta-2-adrenoceptor in isolated membranes of mature erythrocytes from patients with cirrhosis and oesophageal varices. ( De-Madaria, E; Hernández, FT; Horga, JF; Irurzun, J; Palazón, JM; Pascual, S; Perez-Mateo, M; Such, J; Zapater, P, 2006)
"Treatment with propranolol significantly decreased BP and HR for 24 h."2.69Effects of propranolol on cardiovascular and neurohumoral actions of alcohol in hypertensive patients. ( Abe, H; Kawano, Y; Kojima, S; Omae, T; Takishita, S, 1999)
"Atenolol was given at a fixed dose of 100 mg per day."2.66Beta-blockade prevents recurrent gastrointestinal bleeding in well-compensated patients with alcoholic cirrhosis: a multicenter randomized controlled trial. ( Colombo, M; de Franchis, R; Dioguardi, N; Sangiovanni, A; Tommasini, M, 1989)
"Caffeine 2."1.62A MULTIFACTORIAL APPROACH FOR IMPROVING THE SURGICAL PERFORMANCE OF NOVICE VITREORETINAL SURGEONS. ( Belfort Junior, R; Dias Gomes Barrios Marin, V; Eid Farah, M; Gehlbach, PL; Jiramongkolchai, K; Maia, M; Muralha, F; Roizenblatt, M; Treiger Grupenmacher, A, 2021)
"Following development of alcohol dependence, rats exhibit hypersensitivity to the suppressive effects of propranolol on operant alcohol-reinforced responding."1.36Effects of β-adrenoceptor antagonists on alcohol drinking by alcohol-dependent rats. ( Gilpin, NW; Koob, GF, 2010)
"Pretreatment with allopurinol (146 mumols/kg, i."1.28Disturbances in myocardial creatine kinase following ethanol administration to rats--trials of prevention by allopurinol, desferrioxamine and propranolol. ( Hininger, I; Nordmann, R; Ribiere, C, 1991)
" After chronic administration of glucocorticoids, the rate of ethanol elimination was significantly increased, whereas blood acetate concentration showed a tendency to increase, but did not reach statistical significance."1.28The effect of glucocorticoids, beta-2-adrenoceptor agonists, theophylline and propranolol on the rate of ethanol elimination and blood acetate concentration in humans. ( Korri, UM, 1990)
"In talinolol were in the first place dysrhythmias, hypotension and vomiting and nausea, respectively, in propranolol central-nervous symptoms and hypotension."1.27[Acute beta blocker poisoning]. ( Haustein, KO; Knappe, J; Kulick, B; Oltmanns, G; Schmidt, H; Schwela, H, 1985)
"Essential tremor is less incapacitating than parkinsonism and less inexorably progressive."1.26Benign essential tremor: features that aid in diagnosis. ( Paulson, GW, 1982)
"Coexisting cardiac arrhythmia had no influence on prognosis and an arrhythmia only was benign in most patients."1.26Primary myocardial disease. Correlation with clinical findings, angiographic and biopsy diagnosis. Follow-up of 139 patients. ( Hawk, WA; Proudfit, WL; Shirey, EK, 1980)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199019 (55.88)18.7374
1990's5 (14.71)18.2507
2000's2 (5.88)29.6817
2010's6 (17.65)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Roizenblatt, M1
Jiramongkolchai, K1
Gehlbach, PL1
Dias Gomes Barrios Marin, V1
Treiger Grupenmacher, A1
Muralha, F1
Eid Farah, M1
Belfort Junior, R1
Maia, M1
De Oliveira Sergio, T1
Wean, S1
Katner, SN1
Hopf, FW1
Williams, KL1
Harding, KM1
Lee, TH1
Lee, RT1
Rasmussen, DD1
Beckwith, LE1
Kincaid, CL1
Froehlich, JC1
Skelly, MJ1
Chappell, AE1
Carter, E1
Weiner, JL1
Gilpin, NW1
Koob, GF1
Kim, TW1
Kim, HJ1
Chon, CU1
Won, HS1
Park, JH1
Park, DI1
Cho, YK1
Sohn, CI1
Jeon, WK1
Kim, BI1
Deitrich, RA1
Bludeau, P1
Hernández, FT1
Zapater, P1
De-Madaria, E1
Palazón, JM1
Pascual, S1
Irurzun, J1
Such, J1
Perez-Mateo, M1
Horga, JF1
Merker, R1
Schwittek, W1
Kladetzky, RG1
Kuhn, H1
Auzépy, P1
Boukara, N1
Richard, C1
Giudicelli, JF1
Andreas, K1
Fischer, HD1
Schmidt, J1
Kupari, M1
Lindros, K1
Hillbom, M1
Heikkilä, J1
Ylikahri, R1
Ward, K1
Potamianos, G1
Peters, TJ1
Guevara, F1
Orme, ML1
Paulson, GW1
Shirey, EK1
Proudfit, WL1
Hawk, WA1
Sotaniemi, EA1
Anttila, M1
Rautio, A1
Stengård, J1
Saukko, P1
Järvensivu, P1
Kawano, Y1
Abe, H1
Kojima, S1
Takishita, S1
Omae, T1
Simons, LA1
Myant, NB1
Davis, FT1
Chapman, JH1
Schrank, JP1
Crampton, RS1
Luthy, S1
Martinez, TT1
Hininger, I1
Ribiere, C1
Nordmann, R1
Lou, JS1
Jankovic, J1
Korri, UM1
Colombo, M1
de Franchis, R1
Tommasini, M1
Sangiovanni, A1
Dioguardi, N1
Nixon, JV1
Klein, K1
Smucker, MW1
Raven, PB1
Oltmanns, G1
Schwela, H1
Kulick, B1
Knappe, J1
Haustein, KO1
Schmidt, H1
Hilakivi, LA1
Taira, T1
Hilakivi, I1
MacDonald, E1
Tuomisto, L1
Hellevuo, K1
Begleiter, H1
Wigle, ED1
Adelman, AG1
Felderhof, CH1

Trials

3 trials available for propranolol and Alcohol Drinking

ArticleYear
Functional status of beta-2-adrenoceptor in isolated membranes of mature erythrocytes from patients with cirrhosis and oesophageal varices.
    Vascular pharmacology, 2006, Volume: 44, Issue:6

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alcohol Drinking; Cyclic A

2006
Effects of propranolol on cardiovascular and neurohumoral actions of alcohol in hypertensive patients.
    Blood pressure, 1999, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Alcohol Drinking; Asian People; Blood Pressure; Cardiac Ou

1999
Beta-blockade prevents recurrent gastrointestinal bleeding in well-compensated patients with alcoholic cirrhosis: a multicenter randomized controlled trial.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:3

    Topics: Actuarial Analysis; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Atenolol; Clinical Trials a

1989

Other Studies

31 other studies available for propranolol and Alcohol Drinking

ArticleYear
A MULTIFACTORIAL APPROACH FOR IMPROVING THE SURGICAL PERFORMANCE OF NOVICE VITREORETINAL SURGEONS.
    Retina (Philadelphia, Pa.), 2021, Oct-01, Volume: 41, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Alcohol Drinking; Blood Alcohol Content; Caffeine; Central Nervo

2021
The role of beta- and alpha-adrenergic receptors on alcohol drinking.
    Neuropharmacology, 2023, 08-15, Volume: 234

    Topics: Alcohol Drinking; Alcoholism; Animals; Betaxolol; Humans; Male; Norepinephrine; Propranolol; Rats; R

2023
Repeated alcohol extinction sessions in conjunction with MK-801, but not yohimbine or propranolol, reduces subsequent alcohol cue-induced responding in rats.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 116

    Topics: Alcohol Drinking; Animals; Dizocilpine Maleate; Male; Propranolol; Rats; Rats, Long-Evans; Yohimbine

2014
Ask the doctors. I take the beta blocker propranolol twice a day, once in the morning and again in the evening. The drug information label says I should not take propranolol with alcohol. But I like to have two glasses of wine in the evening. Do I nee
    Harvard heart letter : from Harvard Medical School, 2013, Volume: 24, Issue:1

    Topics: Adrenergic beta-Antagonists; Alcohol Drinking; Drug Interactions; Health Behavior; Health Knowledge,

2013
Combining the α1 -adrenergic receptor antagonist, prazosin, with the β-adrenergic receptor antagonist, propranolol, reduces alcohol drinking more effectively than either drug alone.
    Alcoholism, clinical and experimental research, 2014, Volume: 38, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Alcohol Drinking; Alcoholism;

2014
Adolescent social isolation increases anxiety-like behavior and ethanol intake and impairs fear extinction in adulthood: Possible role of disrupted noradrenergic signaling.
    Neuropharmacology, 2015, Volume: 97

    Topics: Aging; Alcohol Drinking; Animals; Anti-Anxiety Agents; Anxiety; Central Nervous System Depressants;

2015
Effects of β-adrenoceptor antagonists on alcohol drinking by alcohol-dependent rats.
    Psychopharmacology, 2010, Volume: 212, Issue:3

    Topics: Adrenergic beta-Antagonists; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Conditioning,

2010
Is there any vindication for low dose nonselective β-blocker medication in patients with liver cirrhosis?
    Clinical and molecular hepatology, 2012, Volume: 18, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Alcohol Drinking; Carcinoma, Hepatocellular; Female; Follo

2012
Interaction between S-propranolol and ethanol in mice selectively bred for ethanol sensitivity: the inbred short- and long-sleep mice.
    Alcoholism, clinical and experimental research, 2003, Volume: 27, Issue:8

    Topics: Alcohol Drinking; Animals; Drug Interactions; Ethanol; Female; Hypothermia; Male; Mice; Mice, Inbred

2003
[Serum lipid levels under chronical treatment with beta-receptor blocking agents in patients with coronary artery disease (author's transl)].
    Zeitschrift fur Kardiologie, 1981, Volume: 70, Issue:6

    Topics: Adrenergic beta-Antagonists; Alcohol Drinking; Cholesterol; Coronary Disease; Diabetes Mellitus; Hum

1981
[Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases].
    Annales de cardiologie et d'angeiologie, 1983, Volume: 32, Issue:4

    Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Alcohol Drinking; Bradycardia; Coma; Dos

1983
[Effect of central effective substances on alcohol preference].
    Biomedica biochimica acta, 1983, Volume: 42, Issue:4

    Topics: Alcohol Drinking; Alcoholism; Animals; Arecoline; Atropine; Central Nervous System Stimulants; Cypro

1983
Cardiovascular effects of acetaldehyde accumulation after ethanol ingestion: their modification by beta-adrenergic blockade and alcohol dehydrogenase inhibition.
    Alcoholism, clinical and experimental research, 1983,Summer, Volume: 7, Issue:3

    Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcohol Drinking; Alcohol Oxidoreductases; Alcoholic Int

1983
Essential tremor: a risk factor for alcoholism?
    British journal of addiction, 1984, Volume: 79, Issue:4

    Topics: Alcohol Drinking; Alcoholism; Humans; Male; Middle Aged; Propranolol; Risk; Tremor

1984
[Behavior of the arterial pressure in patients taking atenolol and propranolol under the influence of alcohol].
    Revista medica de Panama, 1983, Volume: 8, Issue:3

    Topics: Alcohol Drinking; Atenolol; Blood Pressure; Female; Humans; Hypertension; Male; Propranolol

1983
Social drinking and drugs.
    British medical journal (Clinical research ed.), 1981, Dec-05, Volume: 283, Issue:6305

    Topics: Alcohol Drinking; Drug Interactions; Ethanol; Humans; Propranolol; Sotalol

1981
Benign essential tremor: features that aid in diagnosis.
    Postgraduate medicine, 1982, Volume: 71, Issue:1

    Topics: Adolescent; Adult; Aged; Alcohol Drinking; Child; Diagnosis, Differential; Female; Head; Humans; Mal

1982
Primary myocardial disease. Correlation with clinical findings, angiographic and biopsy diagnosis. Follow-up of 139 patients.
    American heart journal, 1980, Volume: 99, Issue:2

    Topics: Alcohol Drinking; Arrhythmias, Cardiac; Biopsy; Cardiac Catheterization; Cardiomyopathies; Cardiomyo

1980
Propranolol and sotalol metabolism after a drinking party.
    Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:6

    Topics: Adult; Alcohol Drinking; Alcoholic Beverages; Blood Pressure; Female; Heart Rate; Humans; Liver; Mal

1981
Cholesterol metabolism in hypertriglyceridaemia and the effects of treatment.
    Clinica chimica acta; international journal of clinical chemistry, 1975, Nov-15, Volume: 65, Issue:1

    Topics: Adult; Alcohol Drinking; Bile Acids and Salts; Cholesterol; Chylomicrons; Diabetes Complications; Di

1975
Proceedings: Abstinence: goal for rehabilitation.
    The American journal of drug and alcohol abuse, 1976, Volume: 3, Issue:1

    Topics: Alcohol Drinking; Alcoholism; Compulsive Behavior; Ethanol; Goals; Humans; Motivation; Propranolol;

1976
Idiopathic ventricular tachycardia. An intracardiac electrical, hemodynamic and angiographic assessment of six patients.
    The American journal of medicine, 1975, Volume: 59, Issue:4

    Topics: Adult; Alcohol Drinking; Angiocardiography; Cardiac Catheterization; Coffee; Diet; Electric Stimulat

1975
Comparison of the effect of isoquinoline analogs and propranolol on voluntary ethanol ingestion.
    Proceedings of the Western Pharmacology Society, 1992, Volume: 35

    Topics: Alcohol Drinking; Animals; Isoquinolines; Propranolol; Rats; Rats, Inbred Strains

1992
Disturbances in myocardial creatine kinase following ethanol administration to rats--trials of prevention by allopurinol, desferrioxamine and propranolol.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1991, Volume: 26, Issue:3

    Topics: Alcohol Drinking; Alcoholic Intoxication; Allopurinol; Animals; Creatine Kinase; Deferoxamine; Dose-

1991
Essential tremor: clinical correlates in 350 patients.
    Neurology, 1991, Volume: 41, Issue:2 ( Pt 1)

    Topics: Adult; Aged; Aging; Alcohol Drinking; Female; Humans; Male; Middle Aged; Movement Disorders; Primido

1991
The effect of glucocorticoids, beta-2-adrenoceptor agonists, theophylline and propranolol on the rate of ethanol elimination and blood acetate concentration in humans.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1990, Volume: 25, Issue:5

    Topics: Acetates; Adolescent; Adult; Albuterol; Alcohol Drinking; Ethanol; Humans; Male; Metabolic Clearance

1990
Effects of acute alcohol ingestion on the left ventricular performance of normal subjects before and after incomplete autonomic blockade.
    The American journal of the medical sciences, 1989, Volume: 298, Issue:3

    Topics: Adult; Alcohol Drinking; Atropine; Autonomic Nerve Block; Heart; Heart Ventricles; Hemodynamics; Hum

1989
[Acute beta blocker poisoning].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1985, Sep-15, Volume: 40, Issue:18

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Alcohol Drinking; Cardiovascular Diseases; Central N

1985
Early postnatal treatment with propranolol affects development of brain amines and behavior.
    Psychopharmacology, 1988, Volume: 96, Issue:3

    Topics: Acoustic Stimulation; Aging; Alcohol Drinking; Animals; Animals, Newborn; Behavior, Animal; Biogenic

1988
Propranolol and alcohol consumption in the rat.
    The American journal of drug and alcohol abuse, 1974, Volume: 1, Issue:1

    Topics: Administration, Oral; Alcohol Drinking; Animals; Behavior, Animal; Ethanol; Food Preferences; Inject

1974
Medical and surgical treatment of the cardiomyopathies.
    Circulation research, 1974, Volume: 35, Issue:2

    Topics: Alcohol Drinking; Anticoagulants; Cardiomyopathies; Cardiomyopathy, Hypertrophic; Diet, Sodium-Restr

1974