Page last updated: 2024-11-03

propranolol and Airway Obstruction

propranolol has been researched along with Airway Obstruction in 40 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.

Research Excerpts

ExcerptRelevanceReference
"1) Describe the origins of the use of propranolol in the treatment of subglottic hemangiomas, 2) Perform meta-analysis of all case reports and series in which propranolol was used to treat subglottic hemangiomas."8.93The use of propranolol in the treatment of subglottic hemangiomas: A literature review and meta-analysis. ( Dodson, KM; Hardison, S; Wan, W, 2016)
"To evaluate the effectiveness of systemic propranolol in airway infantile hemangioma (AIH) treatment."7.81Multicenter Evaluation of the Effectiveness of Systemic Propranolol in the Treatment of Airway Hemangiomas. ( Darrow, DH; Elluru, RG; Friess, MR; Grimmer, JF; Perkins, JA; Richter, GT; Shin, JJ, 2015)
"Four children with haemangiomas of the head and neck were treated with propranolol at a tertiary referral centre."7.77Failure of propranolol in the treatment of childhood haemangiomas of the head and neck. ( Bruce, IA; Goswamy, J; Rothera, MP, 2011)
"Prior to propranolol treatment, laryngotracheobronchoscopy revealed an extensive haemangioma extending from the posterior pharyngeal wall to the subglottis."7.76Use of propranolol to treat multicentric airway haemangioma. ( Mistry, N; Tzifa, K, 2010)
" She was given propranolol after her tracheotomy and had a significant reduction in her subglottic airway obstruction."7.76Propranolol in the management of airway infantile hemangiomas. ( Frieden, IJ; Maguiness, SM; Meyer, AK; Rosbe, KW; Suh, KY, 2010)
"Seven patients presenting with airway obstruction were treated with propranolol."7.76Propranolol for the treatment of airway hemangiomas: a case series and treatment algorithm. ( Chang, KW; Messner, AH; Perkins, JA; Truong, MT, 2010)
" Mean percentage of airway obstruction was 68% (15-90) before propranolol introduction."7.76Propranolol in the therapeutic strategy of infantile laryngotracheal hemangioma: A preliminary retrospective study of French experience. ( Ayari, S; Carrabin, L; Couloigner, V; Cox, A; Denoyelle, F; Fayoux, P; Froehlich, P; Garabédian, EN; Leboulanger, N; Lescanne, E; Marianowski, R; Marie, JP; Mom, T; Mondain, M; Nicollas, R; Roger, G; Teissier, N; Triglia, JM; Van Den Abbeele, T, 2010)
"In the isolated guinea-pig right atria and tracheal strips, both propranolol and YM-09538 caused a parallel shift of the dose-response curve for isoproterenol to the right, indicating that these two drugs block nonselectively the beta 1 1- and beta 2-adrenoceptors."5.26Comparison of airway obstruction induced by propranolol and YM-09538 (a combined alpha- and beta-adrenoceptor blocking drug). ( Takenaka, T; Tomioka, K; Yamada, T, 1982)
"1) Describe the origins of the use of propranolol in the treatment of subglottic hemangiomas, 2) Perform meta-analysis of all case reports and series in which propranolol was used to treat subglottic hemangiomas."4.93The use of propranolol in the treatment of subglottic hemangiomas: A literature review and meta-analysis. ( Dodson, KM; Hardison, S; Wan, W, 2016)
"Cervicofacial segmental infantile hemangiomas (IH) may result in airway obstruction requiring use of propranolol to induce hemangioma regression and reestablish the airway."3.83Use of intravenous propranolol for control of a large cervicofacial hemangioma in a critically ill neonate. ( Fernando, SJ; Krol, A; Leitenberger, S; MacArthur, CJ; Majerus, M, 2016)
"To evaluate the effectiveness of systemic propranolol in airway infantile hemangioma (AIH) treatment."3.81Multicenter Evaluation of the Effectiveness of Systemic Propranolol in the Treatment of Airway Hemangiomas. ( Darrow, DH; Elluru, RG; Friess, MR; Grimmer, JF; Perkins, JA; Richter, GT; Shin, JJ, 2015)
"Four children with haemangiomas of the head and neck were treated with propranolol at a tertiary referral centre."3.77Failure of propranolol in the treatment of childhood haemangiomas of the head and neck. ( Bruce, IA; Goswamy, J; Rothera, MP, 2011)
"Prior to propranolol treatment, laryngotracheobronchoscopy revealed an extensive haemangioma extending from the posterior pharyngeal wall to the subglottis."3.76Use of propranolol to treat multicentric airway haemangioma. ( Mistry, N; Tzifa, K, 2010)
" She was given propranolol after her tracheotomy and had a significant reduction in her subglottic airway obstruction."3.76Propranolol in the management of airway infantile hemangiomas. ( Frieden, IJ; Maguiness, SM; Meyer, AK; Rosbe, KW; Suh, KY, 2010)
"Seven patients presenting with airway obstruction were treated with propranolol."3.76Propranolol for the treatment of airway hemangiomas: a case series and treatment algorithm. ( Chang, KW; Messner, AH; Perkins, JA; Truong, MT, 2010)
" Mean percentage of airway obstruction was 68% (15-90) before propranolol introduction."3.76Propranolol in the therapeutic strategy of infantile laryngotracheal hemangioma: A preliminary retrospective study of French experience. ( Ayari, S; Carrabin, L; Couloigner, V; Cox, A; Denoyelle, F; Fayoux, P; Froehlich, P; Garabédian, EN; Leboulanger, N; Lescanne, E; Marianowski, R; Marie, JP; Mom, T; Mondain, M; Nicollas, R; Roger, G; Teissier, N; Triglia, JM; Van Den Abbeele, T, 2010)
"We examined the response of five ponies with recurrent airway obstruction (principals) and five age- and gender-matched controls to the aerosol alpha-adrenergic agonist phenylephrine after blockade with propranolol and atropine."3.67Alpha 1-adrenergic-induced airway obstruction in ponies with recurrent pulmonary disease. ( Broadstone, RV; Derksen, FJ; Garon, H; Robinson, NE; Scott, JS, 1988)
"Propranolol treatment (2."2.49Propranolol treatment in life-threatening airway hemangiomas: a case series and review of literature. ( Broeks, IJ; Dassel, AC; Hermans, DJ; van Beynum, IM; van der Vleuten, CJ, 2013)
"Bleeding from esophageal varices remains a difficult clinical problem, carrying a high likelihood both of rebleeding and of mortality."2.37Management of the patient with hemorrhaging esophageal varices. ( Cello, JP; Crass, RA; Grendell, JH; Trunkey, DD, 1986)
"In the isolated guinea-pig right atria and tracheal strips, both propranolol and YM-09538 caused a parallel shift of the dose-response curve for isoproterenol to the right, indicating that these two drugs block nonselectively the beta 1 1- and beta 2-adrenoceptors."1.26Comparison of airway obstruction induced by propranolol and YM-09538 (a combined alpha- and beta-adrenoceptor blocking drug). ( Takenaka, T; Tomioka, K; Yamada, T, 1982)
" With the use of semilogarithmic dose-response curves they have shown that 80 mg oral propranolol augmented, whereas oral pretreatment with 400 mg W10294A (an experimental bronchodilator) decreased, histamine and methacholine-induced airway constriction."1.26Modification of induced airway constriction in healthy subjects. ( Bouhuys, A; Littner, MR; Schachter, EN, 1979)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199021 (52.50)18.7374
1990's2 (5.00)18.2507
2000's0 (0.00)29.6817
2010's16 (40.00)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Liang, Y1
Pu, R1
Huang, X1
Li, S1
Chen, Y1
Tang, W1
Darrow, DH2
Rokugo, Y1
Ota, C1
Kimura, M1
Sasahara, Y1
Mendiratta, V1
Varghese, B1
Chander, R1
Parakh, A1
Solanki, RS1
Broeks, IJ1
Hermans, DJ1
Dassel, AC1
van der Vleuten, CJ1
van Beynum, IM1
Lockman, JL1
Schwartz, AJ1
Elluru, RG1
Friess, MR1
Richter, GT1
Grimmer, JF1
Shin, JJ1
Perkins, JA2
Fernando, SJ1
Leitenberger, S1
Majerus, M1
Krol, A1
MacArthur, CJ1
Cheng, CE1
Friedlander, SF1
Hardison, S1
Wan, W1
Dodson, KM1
Truong, MT2
Chang, KW2
Berk, DR1
Heerema-McKenney, A1
Bruckner, AL1
Mistry, N1
Tzifa, K1
Rosbe, KW1
Suh, KY1
Meyer, AK1
Maguiness, SM1
Frieden, IJ1
Messner, AH1
Leboulanger, N1
Fayoux, P1
Teissier, N1
Cox, A1
Van Den Abbeele, T1
Carrabin, L1
Couloigner, V1
Nicollas, R1
Triglia, JM1
Ayari, S1
Froehlich, P1
Lescanne, E1
Marianowski, R1
Mom, T1
Mondain, M1
Marie, JP1
Roger, G1
Garabédian, EN1
Denoyelle, F1
El-Hashim, AZ1
Edafiogho, IO1
Jaffal, SM1
Yousif, MH1
Ezeamuzie, CI1
Kombian, SB1
Goswamy, J1
Rothera, MP1
Bruce, IA1
Newman, BR1
Schultz, LK1
Tomioka, K1
Yamada, T1
Takenaka, T1
Koëter, GH2
Meurs, H1
Jonkman, JH1
de Vries, K1
Kawikova, I1
Arakawa, H1
Petersson, M1
Löfdahl, CG1
Skoogh, BE1
Lötvall, J1
Zinkovska, S1
Kirby, DA1
Turner, P1
Anderson, SD1
Silverman, M1
König, P1
Godfrey, S1
Gayrard, P1
Orehek, J1
Charpin, J1
McGavin, CR1
Williams, IP1
Sinclair, DJ1
Littner, MR1
Schachter, EN1
Bouhuys, A2
Myhre, L1
Röed, A1
Aars, H1
Skinner, C1
Gaddie, J1
Palmer, KN1
Scott, JS1
Garon, H1
Broadstone, RV1
Derksen, FJ1
Robinson, NE1
Cello, JP1
Crass, RA1
Grendell, JH1
Trunkey, DD1
Schaper, M1
Thompson, RD1
Alarie, Y1
Hirschler-Schulte, CJ1
Hylkema, BS1
Coleman, AJ1
Leary, WP1
Hansson, L1
Malmcrona, R1
Olander, R1
Rosenhall, L1
Westerlund, A1
Aberg, H1
Hood, B1
Bengtsson, C1
Souquet, R1
Martoia, R1
Morlain, B1
Nicol, G1
Petiot, JL1
Jacq, J1
Zuskin, E1
Lewis, AJ1
Azarnoff, DL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II, Randomized, Double-Blind Comparison of Corticosteroid and Corticosteroids With Propranolol Treatment of Infantile Hemangiomas (IH)[NCT01074437]Phase 29 participants (Actual)Interventional2010-02-28Terminated (stopped due to Insufficient enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for propranolol and Airway Obstruction

ArticleYear
Management of Infantile Hemangiomas of the Airway.
    Otolaryngologic clinics of North America, 2018, Volume: 51, Issue:1

    Topics: Airway Obstruction; Hemangioma; Humans; Infant; Laser Therapy; Propranolol; Respiratory Tract Neopla

2018
Propranolol treatment in life-threatening airway hemangiomas: a case series and review of literature.
    International journal of pediatric otorhinolaryngology, 2013, Volume: 77, Issue:11

    Topics: Administration, Oral; Airway Obstruction; Biopsy, Needle; Critical Illness; Dose-Response Relationsh

2013
Infantile hemangiomas, complications and treatments.
    Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Airway Obstruction; Drug Therapy, Combination;

2016
The use of propranolol in the treatment of subglottic hemangiomas: A literature review and meta-analysis.
    International journal of pediatric otorhinolaryngology, 2016, Volume: 90

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Airway Obstruction; Endoscopy; Hemangioma; Hum

2016
Management of the patient with hemorrhaging esophageal varices.
    JAMA, 1986, Sep-19, Volume: 256, Issue:11

    Topics: Airway Obstruction; Catheterization; Esophageal and Gastric Varices; Fluid Therapy; Gastrointestinal

1986

Trials

9 trials available for propranolol and Airway Obstruction

ArticleYear
Protective effect of choline theophyllinate on histamine, acetylcholine, and propranolol-induced airflow obstruction.
    Respiration; international review of thoracic diseases, 1984, Volume: 45, Issue:2

    Topics: Acetylcholine; Adolescent; Adult; Airway Obstruction; Bronchodilator Agents; Choline; Female; Forced

1984
The effects of oral propranolol and metoprolol on lung function and exercise performance in chronic airways obstruction.
    British journal of diseases of the chest, 1978, Volume: 72, Issue:4

    Topics: Administration, Oral; Aged; Airway Obstruction; Chronic Disease; Clinical Trials as Topic; Double-Bl

1978
Comparison of effects of propranolol and metoprolol on airways obstruction in chronic bronchitis.
    British medical journal, 1979, Jan-20, Volume: 1, Issue:6157

    Topics: Airway Obstruction; Bronchitis; Clinical Trials as Topic; Double-Blind Method; Forced Expiratory Vol

1979
Comparison of effects of metoprolol and propranolol on asthmatic airway obstruction.
    British medical journal, 1976, Feb-28, Volume: 1, Issue:6008

    Topics: Adult; Airway Obstruction; Airway Resistance; Asthma; Forced Expiratory Volume; Humans; Middle Aged;

1976
Cardiovascular effects of acebutolol (M & B 17803A), in exercising man; a comparative study with practolol and propranolol.
    Current therapeutic research, clinical and experimental, 1972, Volume: 14, Issue:10

    Topics: Acetanilides; Adrenergic beta-Antagonists; Adult; Airway Obstruction; Amino Alcohols; Anilides; Arrh

1972
Propranolol in hypertension. Report on 158 patients treated up to one year.
    Klinische Wochenschrift, 1972, Apr-01, Volume: 50, Issue:7

    Topics: Adult; Aged; Airway Obstruction; Blood Pressure; Bradycardia; Clinical Trials as Topic; Creatinine;

1972
Long-term effect of alprenolol as antihypertensive agent.
    Acta medica Scandinavica. Supplementum, 1974, Volume: 554

    Topics: Adult; Airway Obstruction; Alprenolol; Blood Pressure; Body Weight; Chlorthalidone; Clinical Trials

1974
[Propranolol test in asthmatic patients (apropos of 102 cases)].
    Le Poumon et le coeur, 1974, Volume: 30, Issue:3

    Topics: Acetylcholine; Adult; Aerosols; Airway Obstruction; Asthma; Bronchitis; Clinical Trials as Topic; Dr

1974
Inhibition of histamine-induced airway constriction by ascorbic acid.
    The Journal of allergy and clinical immunology, 1973, Volume: 51, Issue:4

    Topics: Airway Obstruction; Animals; Ascorbic Acid; Constriction; Guinea Pigs; Histamine; Humans; Placebos;

1973

Other Studies

26 other studies available for propranolol and Airway Obstruction

ArticleYear
Airway obstruction as the primary manifestation of infantile thyroid hemangioma.
    Italian journal of pediatrics, 2020, Oct-19, Volume: 46, Issue:1

    Topics: Adrenergic beta-Antagonists; Airway Obstruction; Diagnosis, Differential; Diagnostic Imaging; Female

2020
Preoperative administration of propranolol reduced the surgical risks of PHACES syndrome in a 14-month-old girl.
    BMJ case reports, 2019, Apr-29, Volume: 12, Issue:4

    Topics: Abnormalities, Multiple; Administration, Oral; Adrenergic beta-Antagonists; Airway Obstruction; Aort

2019
Successful management of airway hemangioma with propranolol.
    International journal of dermatology, 2013, Volume: 52, Issue:6

    Topics: Adrenergic beta-Antagonists; Airway Obstruction; Epiglottis; Female; Head and Neck Neoplasms; Hemang

2013
Infantile Hemangioma in the Airway.
    Anesthesiology, 2015, Volume: 123, Issue:6

    Topics: Airway Obstruction; Biopsy; Hemangioma; Humans; Infant; Laryngoscopy; Propranolol; Respiratory Sound

2015
Multicenter Evaluation of the Effectiveness of Systemic Propranolol in the Treatment of Airway Hemangiomas.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2015, Volume: 153, Issue:3

    Topics: Airway Obstruction; Endoscopy; Female; Hemangioma; Humans; Infant; Infant, Newborn; Laryngeal Neopla

2015
Use of intravenous propranolol for control of a large cervicofacial hemangioma in a critically ill neonate.
    International journal of pediatric otorhinolaryngology, 2016, Volume: 84

    Topics: Airway Obstruction; Critical Illness; Enterocolitis, Necrotizing; Female; Hemangioma, Capillary; Hum

2016
Propranolol for the treatment of a life-threatening subglottic and mediastinal infantile hemangioma.
    The Journal of pediatrics, 2010, Volume: 156, Issue:2

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Airway Obstruction; Antineoplastic Agents, Hormon

2010
Use of propranolol to treat multicentric airway haemangioma.
    The Journal of laryngology and otology, 2010, Volume: 124, Issue:12

    Topics: Adrenergic beta-Antagonists; Airway Obstruction; Anti-Inflammatory Agents; Dexamethasone; Endoscopy;

2010
Propranolol in the management of airway infantile hemangiomas.
    Archives of otolaryngology--head & neck surgery, 2010, Volume: 136, Issue:7

    Topics: Adrenal Cortex Hormones; Airway Obstruction; Combined Modality Therapy; Drug Therapy, Combination; F

2010
Propranolol for the treatment of airway hemangiomas: a case series and treatment algorithm.
    International journal of pediatric otorhinolaryngology, 2010, Volume: 74, Issue:9

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Airway Obstruction; Female; Hemangioma; Humans; I

2010
Propranolol in the therapeutic strategy of infantile laryngotracheal hemangioma: A preliminary retrospective study of French experience.
    International journal of pediatric otorhinolaryngology, 2010, Volume: 74, Issue:11

    Topics: Adrenergic beta-Antagonists; Airway Obstruction; Drug Resistance; Hemangioma; Humans; Infant; Infant

2010
Anti-tussive and bronchodilator mechanisms of action for the enaminone E121.
    Life sciences, 2011, Sep-12, Volume: 89, Issue:11-12

    Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Airway Obstruction; Aniline Compounds; Anim

2011
Failure of propranolol in the treatment of childhood haemangiomas of the head and neck.
    The Journal of laryngology and otology, 2011, Volume: 125, Issue:11

    Topics: Adrenal Cortex Hormones; Airway Obstruction; Anti-Inflammatory Agents; Combined Modality Therapy; Co

2011
Epinephrine-resistant anaphylaxis in a patient taking propranolol hydrochloride.
    Annals of allergy, 1981, Volume: 47, Issue:1

    Topics: Adrenergic beta-Antagonists; Airway Obstruction; Anaphylaxis; Drug Resistance; Epinephrine; Female;

1981
Comparison of airway obstruction induced by propranolol and YM-09538 (a combined alpha- and beta-adrenoceptor blocking drug).
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 256, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Airway Obstruction; Airway Resistance; An

1982
Bradykinin-induced release of thromboxane B2 into bronchoalveolar lavage fluid of guinea pigs: relationship to airflow obstruction.
    European journal of pharmacology, 1995, Jul-14, Volume: 280, Issue:3

    Topics: Airway Obstruction; Animals; Azepines; Bradykinin; Bronchoalveolar Lavage Fluid; Dioxanes; Guinea Pi

1995
Intracerebroventricular propranolol prevented vascular resistance increases on arousal from sleep apnea.
    Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 82, Issue:5

    Topics: Adrenergic beta-Antagonists; Airway Obstruction; Animals; Arousal; Endothelium, Vascular; Hemodynami

1997
Relative importance of cardioselectivity and partial agonism in the treatment of hypertension in the patient with air-flow obstruction.
    Cardiology, 1979, Volume: 64 Suppl 1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Airway Obstruction; Heart; Humans; Hypertensi

1979
Exercise-induced asthma.
    British journal of diseases of the chest, 1975, Volume: 69, Issue:1

    Topics: Acidosis, Respiratory; Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Airway Obstruction; Air

1975
[Induced beta-adrenergic stimulation and blockade in asthma bronchomotor effects (author's transl)].
    Respiration; international review of thoracic diseases, 1975, Volume: 32, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Airway Obstruction; Airway Resistance; Albute

1975
Modification of induced airway constriction in healthy subjects.
    Annals of allergy, 1979, Volume: 43, Issue:3

    Topics: Adult; Aerosols; Airway Obstruction; Bronchodilator Agents; Dose-Response Relationship, Drug; Female

1979
Inhibitory effect of propranolol on tetanic contraction in rabbit.
    European journal of pharmacology, 1977, Apr-21, Volume: 42, Issue:4

    Topics: Airway Obstruction; Animals; Depression, Chemical; Diaphragm; Electric Stimulation; Electromyography

1977
Alpha 1-adrenergic-induced airway obstruction in ponies with recurrent pulmonary disease.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:2

    Topics: Airway Obstruction; Airway Resistance; Animals; Atropine; Dose-Response Relationship, Drug; Female;

1988
A method to classify airborne chemicals which alter the normal ventilatory response induced by CO2.
    Toxicology and applied pharmacology, 1985, Jun-30, Volume: 79, Issue:2

    Topics: Aerosols; Airway Obstruction; Animals; Carbachol; Carbon Dioxide; Drug Combinations; Guinea Pigs; Pl

1985
[No beta blockers without a COPD anamnesis].
    Nederlands tijdschrift voor geneeskunde, 1985, Feb-09, Volume: 129, Issue:6

    Topics: Acute Disease; Airway Obstruction; Female; Humans; Lung Diseases, Obstructive; Medical History Takin

1985
Use of pharmacokinetic principles in therapy.
    The New England journal of medicine, 1973, Sep-20, Volume: 289, Issue:12

    Topics: Airway Obstruction; Animals; Drug Therapy; Half-Life; Humans; Kinetics; Pharmaceutical Preparations;

1973