propranolol has been researched along with Age-Related Memory Disorders in 27 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Twenty-six adult men with mild essential hypertension received either a placebo or a beta blocker (atenolol or propranolol) for 2 weeks." | 5.06 | Memory performance by mild hypertensives following beta-adrenergic blockade. ( Blumenthal, JA; Ekelund, LG; Krantz, DS; Light, KC; Madden, DJ; McKee, DC, 1986) |
| "β-blockers have been shown to improve survival after traumatic brain injury (TBI); however, the impact of continuous dosage of β-blockers on cognitive function has not been elucidated." | 1.51 | Propranolol attenuates cognitive, learning, and memory deficits in a murine model of traumatic brain injury. ( Bae, EH; Friese, RS; Gries, L; Hamidi, M; Hanna, K; Joseph, B; Kulvatunyou, N; OʼKeeffe, T; Tang, A; Zakaria, ER; Zeeshan, M, 2019) |
| "Propranolol use has been examined in three phases of memory, including acquisition, formation, and encoding; emotional response and consolidation; and retrieval and reconsolidation." | 1.36 | Propranolol use in the prevention and treatment of posttraumatic stress disorder in military veterans: forgetting therapy revisited. ( Donovan, E, 2010) |
| " These data demonstrate that chronic dosing with propranolol can impair retention of spatial learning, which cannot be attributed to reduced arousal or motor function." | 1.31 | Chronic propranolol induces deficits in retention but not acquisition performance in the water maze in mice. ( Czech, DA; Laubmeier, KK; Nielson, KA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.41) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 7 (25.93) | 29.6817 |
| 2010's | 14 (51.85) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Mallet, C | 1 |
| Chick, CF | 1 |
| Maatoug, R | 1 |
| Fossati, P | 1 |
| Brunet, A | 1 |
| Millet, B | 1 |
| Zeeshan, M | 1 |
| Hamidi, M | 1 |
| OʼKeeffe, T | 1 |
| Bae, EH | 1 |
| Hanna, K | 1 |
| Friese, RS | 1 |
| Kulvatunyou, N | 1 |
| Zakaria, ER | 1 |
| Gries, L | 1 |
| Tang, A | 1 |
| Joseph, B | 1 |
| Ciprés-Flores, FJ | 1 |
| Farfán-García, ED | 1 |
| Andrade-Jorge, E | 1 |
| Cuevas-Hernández, RI | 1 |
| Tamay-Cach, F | 1 |
| Martínez-Archundia, M | 1 |
| Trujillo-Ferrara, JG | 1 |
| Soriano-Ursúa, MA | 1 |
| Giustino, TF | 1 |
| Seemann, JR | 1 |
| Acca, GM | 1 |
| Goode, TD | 1 |
| Fitzgerald, PJ | 1 |
| Maren, S | 1 |
| Nasehi, M | 1 |
| Khani-Abyaneh, M | 1 |
| Ebrahimi-Ghiri, M | 1 |
| Zarrindast, MR | 2 |
| Zhu, RT | 1 |
| Liu, XH | 1 |
| Shi, YW | 1 |
| Wang, XG | 1 |
| Xue, L | 1 |
| Zhao, H | 1 |
| McReynolds, JR | 2 |
| Holloway-Erickson, CM | 1 |
| Parmar, TU | 1 |
| McIntyre, CK | 1 |
| Donovan, E | 1 |
| Reyes-López, J | 1 |
| Nuñez-Jaramillo, L | 1 |
| Morán-Guel, E | 1 |
| Miranda, MI | 1 |
| Otis, JM | 1 |
| Mueller, D | 1 |
| Sun, H | 1 |
| Mao, Y | 1 |
| Wang, J | 1 |
| Ma, Y | 1 |
| Soeter, M | 2 |
| Kindt, M | 2 |
| Bodner, KE | 1 |
| Beversdorf, DQ | 1 |
| Saklayen, SS | 1 |
| Christ, SE | 1 |
| Willyard, C | 1 |
| Dobarro, M | 1 |
| Orejana, L | 1 |
| Aguirre, N | 1 |
| Ramírez, MJ | 1 |
| Roozendaal, B | 3 |
| McGaugh, JL | 2 |
| de Quervain, DJ | 2 |
| Schelling, G | 1 |
| Haidari, H | 1 |
| Jafari, MR | 1 |
| Djahanguiri, B | 1 |
| Aerni, A | 1 |
| Campbell, AM | 1 |
| Park, CR | 1 |
| Zoladz, PR | 1 |
| Muñoz, C | 1 |
| Fleshner, M | 1 |
| Diamond, DM | 1 |
| Kenton, L | 1 |
| Boon, F | 1 |
| Cain, DP | 1 |
| Cummings, J | 1 |
| Hebben, NA | 1 |
| Obler, L | 1 |
| Leonard, P | 1 |
| Ohno, M | 2 |
| Yamamoto, T | 1 |
| Watanabe, S | 2 |
| Yoshimatsu, A | 1 |
| Kobayashi, M | 1 |
| Czech, DA | 1 |
| Nielson, KA | 1 |
| Laubmeier, KK | 1 |
| Madden, DJ | 1 |
| Blumenthal, JA | 1 |
| Ekelund, LG | 1 |
| Krantz, DS | 1 |
| Light, KC | 1 |
| McKee, DC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Using Reconsolidation Blockade to Treat Trauma Related Disorders After Paris Attacks: an Effectiveness Study[NCT02789982] | Phase 3 | 364 participants (Actual) | Interventional | 2016-05-27 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for propranolol and Age-Related Memory Disorders
| Article | Year |
|---|---|
Stimulation of the noradrenergic system during memory formation impairs extinction learning but not the disruption of reconsolidation.
Topics: Adolescent; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Analysis of | 2012 |
Noradrenergic moderation of working memory impairments in adults with autism spectrum disorder.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Attention; Case-Control Studies; Child; Child Develo | 2012 |
Preventive effect of beta-adrenoceptor blockade on glucocorticoid-induced memory retrieval deficits.
Topics: Adrenergic beta-Antagonists; Adult; Arousal; Cortisone; Double-Blind Method; Emotions; Female; Gluco | 2007 |
Memory performance by mild hypertensives following beta-adrenergic blockade.
Topics: Adult; Atenolol; Heart Rate; Humans; Hypertension; Male; Memory Disorders; Middle Aged; Propranolol; | 1986 |
23 other studies available for propranolol and Age-Related Memory Disorders
| Article | Year |
|---|---|
Memory reconsolidation impairment using the β-adrenergic receptor blocker propranolol reduces nightmare severity in patients with posttraumatic stress disorder: a preliminary study.
Topics: Adrenergic beta-Antagonists; Dreams; Humans; Memory Disorders; Propranolol; Prospective Studies; Rec | 2022 |
Propranolol attenuates cognitive, learning, and memory deficits in a murine model of traumatic brain injury.
Topics: Adrenergic beta-Antagonists; Animals; Apoptosis; Brain Injuries, Traumatic; CA1 Region, Hippocampal; | 2019 |
Identification of two arylimides as cholinesterase inhibitors and testing of propranolol addition on impaired rat memory.
Topics: Amides; Animals; Cholinesterase Inhibitors; Computer Simulation; Disease Models, Animal; Drug Therap | 2020 |
β-Adrenoceptor Blockade in the Basolateral Amygdala, But Not the Medial Prefrontal Cortex, Rescues the Immediate Extinction Deficit.
Topics: Adrenergic beta-Antagonists; Animals; Auditory Perception; Basolateral Nuclear Complex; Extinction, | 2017 |
The effect of left frontal transcranial direct-current stimulation on propranolol-induced fear memory acquisition and consolidation deficits.
Topics: Animals; Fear; Learning; Male; Memory; Memory Disorders; Mice; Neuropsychological Tests; Prefrontal | 2017 |
Propranolol can induce PTSD-like memory impairments in rats.
Topics: Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fear | 2018 |
Corticosterone-induced enhancement of memory and synaptic Arc protein in the medial prefrontal cortex.
Topics: Adrenergic beta-Antagonists; Animals; Basolateral Nuclear Complex; Corticosterone; Cytoskeletal Prot | 2014 |
Propranolol use in the prevention and treatment of posttraumatic stress disorder in military veterans: forgetting therapy revisited.
Topics: Adrenergic beta-Antagonists; Ethics, Clinical; Humans; Memory; Memory Disorders; Military Personnel; | 2010 |
Differential effects of beta-adrenergic receptor blockade in the medial prefrontal cortex during aversive and incidental taste memory formation.
Topics: Adrenergic beta-Antagonists; Animals; Appetitive Behavior; Avoidance Learning; Conditioning, Classic | 2010 |
Inhibition of β-adrenergic receptors induces a persistent deficit in retrieval of a cocaine-associated memory providing protection against reinstatement.
Topics: Adrenergic beta-Antagonists; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychologica | 2011 |
Effects of beta-adrenergic antagonist, propranolol on spatial memory and exploratory behavior in mice.
Topics: Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Exploratory Behavior; Locomo | 2011 |
Disrupting reconsolidation: pharmacological and behavioral manipulations.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; alpha-Amylases; Analysis of Variance; Blood Pressure | 2011 |
Remembered for forgetting.
Topics: Adrenergic beta-Antagonists; Analgesics, Opioid; Emotions; Humans; Memory Disorders; Mental Recall; | 2012 |
Propranolol restores cognitive deficits and improves amyloid and Tau pathologies in a senescence-accelerated mouse model.
Topics: Adrenergic beta-Antagonists; Aging; Amyloid Neuropathies; Animals; Antihypertensive Agents; Biomarke | 2013 |
The basolateral amygdala interacts with the medial prefrontal cortex in regulating glucocorticoid effects on working memory impairment.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amygdala; Analysis of Variance; Androstanols; | 2004 |
A systemically administered beta-adrenoceptor antagonist blocks corticosterone-induced impairment of contextual memory retrieval in rats.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Corticosterone; Dru | 2004 |
Influence of beta-adrenoceptor agonists and antagonists on baclofen-induced memory impairment in mice.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Animals, Outbred Strains; | 2004 |
Pre-training administration of tianeptine, but not propranolol, protects hippocampus-dependent memory from being impaired by predator stress.
Topics: Adrenergic beta-Antagonists; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticoste | 2008 |
Combined but not individual administration of beta-adrenergic and serotonergic antagonists impairs water maze acquisition in the rat.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relation | 2008 |
Nonaphasic misnaming and other neurobehavioral features of an unusual toxic encephalopathy: case study.
Topics: Aged; Brain Diseases; Humans; Language Disorders; Male; Memory Disorders; Mental Disorders; Proprano | 1980 |
Working memory deficits induced by intrahippocampal administration of 8-OH-DPAT, a 5-HT1A receptor agonist, in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Hippocampus; Male; Memory Disorders; Memory, Short- | 1993 |
Beta-adrenergic dysfunction exacerbates impairment of working memory induced by hippocampal NMDA receptor blockade in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Excitatory Ami | 1996 |
Chronic propranolol induces deficits in retention but not acquisition performance in the water maze in mice.
Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Drug Administration Schedule; Male; Maze Lea | 2000 |