propranolol has been researched along with African Sleeping Sickness in 2 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The compound was orally bioavailable and displayed good plasma and brain exposure in mice." | 1.40 | Substituted 2-phenylimidazopyridines: a new class of drug leads for human African trypanosomiasis. ( Brun, R; Buckner, FS; Chatterjee, AK; Creason, SA; Duster, NA; Gelb, MH; Gillespie, JR; Glynne, R; Hulverson, MA; McQueen, J; Molteni, V; Nagendar, P; Nagle, A; Norcross, NR; Ranade, RM; Supek, F; Tatipaka, HB; Wenzler, T, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tatipaka, HB | 1 |
| Gillespie, JR | 1 |
| Chatterjee, AK | 1 |
| Norcross, NR | 1 |
| Hulverson, MA | 1 |
| Ranade, RM | 1 |
| Nagendar, P | 1 |
| Creason, SA | 1 |
| McQueen, J | 1 |
| Duster, NA | 1 |
| Nagle, A | 1 |
| Supek, F | 1 |
| Molteni, V | 1 |
| Wenzler, T | 1 |
| Brun, R | 1 |
| Glynne, R | 1 |
| Buckner, FS | 1 |
| Gelb, MH | 1 |
| Thompson, AM | 1 |
| Marshall, AJ | 1 |
| Maes, L | 1 |
| Yarlett, N | 1 |
| Bacchi, CJ | 1 |
| Gaukel, E | 1 |
| Wring, SA | 1 |
| Launay, D | 1 |
| Braillard, S | 1 |
| Chatelain, E | 1 |
| Mowbray, CE | 1 |
| Denny, WA | 1 |
2 other studies available for propranolol and African Sleeping Sickness
| Article | Year |
|---|---|
Substituted 2-phenylimidazopyridines: a new class of drug leads for human African trypanosomiasis.
Topics: Administration, Oral; Animals; Biological Availability; Cell Line, Tumor; Cell Membrane Permeability | 2014 |
Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.
Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mic | 2018 |