propranolol has been researched along with Adverse Drug Event in 42 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although propranolol has been established as the gold standard when treatment is sought for infantile hemangioma, concerns over its side effect profile have led to increasing usage of atenolol, a beta-1 selective blocker." | 9.41 | Should Propranolol Remain the Gold Standard for Treatment of Infantile Hemangioma? A Systematic Review and Meta-Analysis of Propranolol Versus Atenolol. ( Carroll, W; Chen, T; Clemmens, C; Gudipudi, R; Nguyen, SA, 2023) |
| "A number of clinical trials evaluated the effect of topical timolol in the treatment of infantile hemangioma and provided inconsistent results." | 8.98 | Effect of topical timolol on response rate and adverse events in infantile hemangioma: a meta-analysis. ( Li, Y; Zheng, L, 2018) |
| "To assess the adverse effects of propranolol therapy in infantile hemangioma." | 8.02 | Adverse Drug Reactions Following Propranolol in Infantile Hemangioma. ( Imran, M; Kumar, D; Mishra, A; Pandey, V; Sharma, SP; Tiwari, P, 2021) |
| "There is no definitive conclusion regarding the optimal timing for terminating propranolol treatment for infantile hemangioma (IH)." | 7.85 | When to stop propranolol for infantile hemangioma. ( Chang, L; Chen, H; Gu, Y; Jin, Y; Lin, X; Ma, G; Qiu, Y; Ying, H; Yu, Z, 2017) |
| "An open observational prospective study was performed over 25 months in a group of pediatric patients diagnosed with infantile hemangioma treated with propranolol." | 7.83 | The Role of the Pharmacist in the Treatment of Patients with Infantile Hemangioma Using Propranolol. ( Castaneda, S; De la Cruz, H; Garcia, E; Melendez-Lopez, S; Sanchez-Palacio, J, 2016) |
| "Although propranolol has been established as the gold standard when treatment is sought for infantile hemangioma, concerns over its side effect profile have led to increasing usage of atenolol, a beta-1 selective blocker." | 5.41 | Should Propranolol Remain the Gold Standard for Treatment of Infantile Hemangioma? A Systematic Review and Meta-Analysis of Propranolol Versus Atenolol. ( Carroll, W; Chen, T; Clemmens, C; Gudipudi, R; Nguyen, SA, 2023) |
| "A number of clinical trials evaluated the effect of topical timolol in the treatment of infantile hemangioma and provided inconsistent results." | 4.98 | Effect of topical timolol on response rate and adverse events in infantile hemangioma: a meta-analysis. ( Li, Y; Zheng, L, 2018) |
| "Drugs that have been associated with the precipitation or exacerbation of psoriasis include lithium, beta adrenergic receptor blocking agents, and antimalarials." | 4.77 | Drugs in exacerbation of psoriasis. ( Abel, EA; DiCicco, LM; Farber, EM; Fraki, JE; Orenberg, EK, 1986) |
| "To assess the adverse effects of propranolol therapy in infantile hemangioma." | 4.02 | Adverse Drug Reactions Following Propranolol in Infantile Hemangioma. ( Imran, M; Kumar, D; Mishra, A; Pandey, V; Sharma, SP; Tiwari, P, 2021) |
| " Out of 439 patients, 292 were enrolled to examine the effect of propranolol on 2-year-olds' height and body weight (BW), by comparison with reference range and among groups." | 3.91 | Propranolol Treatment for Infantile Hemangiomas: Short-Term Adverse Effects and Follow-Up to Age Two. ( Huo, R; Li, H; Li, X; Yang, K, 2019) |
| "There is no definitive conclusion regarding the optimal timing for terminating propranolol treatment for infantile hemangioma (IH)." | 3.85 | When to stop propranolol for infantile hemangioma. ( Chang, L; Chen, H; Gu, Y; Jin, Y; Lin, X; Ma, G; Qiu, Y; Ying, H; Yu, Z, 2017) |
| "An open observational prospective study was performed over 25 months in a group of pediatric patients diagnosed with infantile hemangioma treated with propranolol." | 3.83 | The Role of the Pharmacist in the Treatment of Patients with Infantile Hemangioma Using Propranolol. ( Castaneda, S; De la Cruz, H; Garcia, E; Melendez-Lopez, S; Sanchez-Palacio, J, 2016) |
| "Beta-blockers are effective for migraine attack prophylaxis but are associated with dizziness and fatigue and are contraindicated in patients with certain co-morbidities, including asthma, congestive heart failure, and abnormal cardiac rhythms." | 3.01 | Non-CGRP Antagonist/Non-Triptan Options for Migraine Disease Treatment: Clinical Considerations. ( Ahmadzadeh, S; Bocklud, BE; Corley, SC; Granier, MA; Ingram, EE; Kaye, AD; Neuchat, EE; Shekoohi, S, 2023) |
| " The comparison between topical propranolol and oral propranolol led to no discovery of significant difference in the incidence of adverse effects (OR = 1." | 2.66 | The effectiveness and safety of topical β-receptor blocker in treating superficial infantile haemangiomas: A meta-analysis including 20 studies. ( Li, H; Lin, Z; Yu, Z; Zhang, B, 2020) |
| "While options for treatment strategies for infantile hemangiomas (IH) are numerous, evidence-based information about agents, optimal dosage, adverse effects, treatment modality, pretreatment and treatment strategies remain limited." | 2.53 | Treatment of infantile hemangiomas: therapeutic options in regard to side effects and adverse events - a review of the literature. ( Breugem, CC; Breur, JM; Elbert, NJ; Kon, M; Liem, YT; Pasmans, SG; Raphael, MF; Vlasveld, FA, 2016) |
| " Atenolol and prednisolone are effective and safe alternatives to propranolol in the treatment of refractory IHs." | 1.48 | Intolerable side effects during propranolol therapy for infantile hemangioma: frequency, risk factors and management. ( Chen, S; Ji, Y; Lu, G; Qiu, L; Wang, Q; Xiang, B; Xu, Z; Yang, K; Zhong, L, 2018) |
| "Phospholipidosis (PLD) is a lysosomal storage disorder induced by compounds, notably cationic amphiphilic drugs, which although reversible interferes with cellular phospholipids." | 1.38 | In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. ( Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T, 2012) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (38.10) | 18.7374 |
| 1990's | 2 (4.76) | 18.2507 |
| 2000's | 4 (9.52) | 29.6817 |
| 2010's | 15 (35.71) | 24.3611 |
| 2020's | 5 (11.90) | 2.80 |
| Authors | Studies |
|---|---|
| Pedersen, JM | 1 |
| Matsson, P | 1 |
| Bergström, CA | 1 |
| Norinder, U | 1 |
| Hoogstraate, J | 1 |
| Artursson, P | 1 |
| Chen, M | 1 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 2 |
| Dawson, S | 1 |
| Stahl, S | 1 |
| Paul, N | 1 |
| Barber, J | 1 |
| Kenna, JG | 1 |
| Fischer, H | 1 |
| Atzpodien, EA | 1 |
| Csato, M | 1 |
| Doessegger, L | 1 |
| Lenz, B | 1 |
| Schmitt, G | 1 |
| Singer, T | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Pandey, V | 1 |
| Tiwari, P | 1 |
| Imran, M | 1 |
| Mishra, A | 1 |
| Kumar, D | 1 |
| Sharma, SP | 1 |
| Chen, T | 1 |
| Gudipudi, R | 1 |
| Nguyen, SA | 1 |
| Carroll, W | 1 |
| Clemmens, C | 1 |
| Pensabene, M | 1 |
| Di Pace, MR | 1 |
| Baldanza, F | 1 |
| Grasso, F | 1 |
| Patti, M | 1 |
| Sergio, M | 1 |
| La Placa, S | 1 |
| Giuffre', M | 1 |
| Serra, G | 1 |
| Casuccio, A | 1 |
| Cimador, M | 1 |
| Ingram, EE | 1 |
| Bocklud, BE | 1 |
| Corley, SC | 1 |
| Granier, MA | 1 |
| Neuchat, EE | 1 |
| Ahmadzadeh, S | 1 |
| Shekoohi, S | 1 |
| Kaye, AD | 1 |
| Lin, Z | 1 |
| Zhang, B | 1 |
| Yu, Z | 2 |
| Li, H | 2 |
| Li, X | 1 |
| Yang, K | 2 |
| Huo, R | 1 |
| Zheng, L | 1 |
| Li, Y | 1 |
| Ji, Y | 1 |
| Chen, S | 1 |
| Wang, Q | 1 |
| Xiang, B | 1 |
| Xu, Z | 1 |
| Zhong, L | 1 |
| Lu, G | 1 |
| Qiu, L | 1 |
| Pessoa, TL | 1 |
| Clemente Junior, WS | 1 |
| Costa, TXD | 1 |
| Bezerra, PKDV | 1 |
| Martins, RR | 1 |
| Kwon, EK | 1 |
| Joachim, S | 1 |
| Siegel, DH | 1 |
| Drolet, BA | 1 |
| Holland, K | 1 |
| Dyer, JA | 1 |
| Raphael, MF | 1 |
| Breur, JM | 1 |
| Vlasveld, FA | 1 |
| Elbert, NJ | 1 |
| Liem, YT | 1 |
| Kon, M | 1 |
| Breugem, CC | 1 |
| Pasmans, SG | 1 |
| Castaneda, S | 1 |
| Melendez-Lopez, S | 1 |
| Garcia, E | 1 |
| De la Cruz, H | 1 |
| Sanchez-Palacio, J | 1 |
| Chang, L | 1 |
| Gu, Y | 1 |
| Ying, H | 1 |
| Qiu, Y | 1 |
| Ma, G | 1 |
| Chen, H | 1 |
| Jin, Y | 1 |
| Lin, X | 1 |
| Ferrari, B | 1 |
| Mons, R | 1 |
| Vollat, B | 1 |
| Fraysse, B | 1 |
| Paxéus, N | 1 |
| Lo Giudice, R | 1 |
| Pollio, A | 1 |
| Garric, J | 1 |
| Fountoulakis, M | 1 |
| Drillia, P | 1 |
| Stamatelatou, K | 1 |
| Lyberatos, G | 2 |
| Dokianakis, SN | 1 |
| Kornaros, ME | 1 |
| Clark, BG | 1 |
| Vestal, RE | 1 |
| Urquhart, J | 1 |
| Fara, JW | 1 |
| Willis, KL | 1 |
| Melmon, KL | 1 |
| Nierenberg, DW | 1 |
| Sørensen, TI | 1 |
| Nederfors, T | 1 |
| Smith, CR | 1 |
| Filipek, WJ | 1 |
| Reus, VI | 1 |
| Levine, L | 1 |
| von Wichert, P | 1 |
| Seltzer, HS | 1 |
| Fine, SR | 1 |
| Abel, EA | 1 |
| DiCicco, LM | 1 |
| Orenberg, EK | 1 |
| Fraki, JE | 1 |
| Farber, EM | 1 |
| Stankiewicz, A | 1 |
| Hovland, KR | 1 |
| Jacobson, J | 1 |
12 reviews available for propranolol and Adverse Drug Event
| Article | Year |
|---|---|
Should Propranolol Remain the Gold Standard for Treatment of Infantile Hemangioma? A Systematic Review and Meta-Analysis of Propranolol Versus Atenolol.
Topics: Adrenergic beta-Antagonists; Atenolol; Drug-Related Side Effects and Adverse Reactions; Hemangioma; | 2023 |
Non-CGRP Antagonist/Non-Triptan Options for Migraine Disease Treatment: Clinical Considerations.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Calcium Channel Blockers; Drug-Relat | 2023 |
The effectiveness and safety of topical β-receptor blocker in treating superficial infantile haemangiomas: A meta-analysis including 20 studies.
Topics: Administration, Topical; Adrenergic beta-Antagonists; China; Drug-Related Side Effects and Adverse R | 2020 |
Effect of topical timolol on response rate and adverse events in infantile hemangioma: a meta-analysis.
Topics: Administration, Topical; Clinical Trials as Topic; Drug-Related Side Effects and Adverse Reactions; | 2018 |
Retrospective review of adverse effects from propranolol in infants.
Topics: Adrenergic beta-Antagonists; Cardiovascular Diseases; Child; Drug-Related Side Effects and Adverse R | 2013 |
Treatment of infantile hemangiomas: therapeutic options in regard to side effects and adverse events - a review of the literature.
Topics: Adrenergic beta-Antagonists; Drug-Related Side Effects and Adverse Reactions; Hemangioma; Humans; In | 2016 |
Rate-controlled delivery systems in drug and hormone research.
Topics: Animals; Antihypertensive Agents; Circadian Rhythm; Drug Implants; Drug Tolerance; Drug-Related Side | 1984 |
Drug-induced pulmonary disease.
Topics: Adrenal Cortex Hormones; Analgesics; Anti-Infective Agents; Antihypertensive Agents; Antineoplastic | 1979 |
Reported ocular side effects of the ten most frequently prescribed drugs.
Topics: Acetaminophen; Ampicillin; Brompheniramine; Codeine; Diazepam; Digoxin; Drug Prescriptions; Drug-Rel | 1979 |
Drugs in exacerbation of psoriasis.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Anthralin; Anti-Inflammatory Agents, Non-Stero | 1986 |
[Selected problems of pharmacology and toxicology of the eye].
Topics: Acetazolamide; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Drug-Related Side Effects an | 1970 |
Effects of drugs on aqueous humor dynamics.
Topics: Adrenal Cortex Hormones; Anesthetics; Animals; Carbonic Anhydrase Inhibitors; Cats; Chymotrypsin; Co | 1971 |
30 other studies available for propranolol and Adverse Drug Event
| Article | Year |
|---|---|
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Bi | 2008 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse | 2012 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Adverse Drug Reactions Following Propranolol in Infantile Hemangioma.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Child; Child, Preschool; Drug-Related Side Effect | 2021 |
Quality of life improving after propranolol treatment in patients with Infantile Hemangiomas.
Topics: Administration, Oral; Drug-Related Side Effects and Adverse Reactions; Hemangioma, Capillary; Humans | 2022 |
Propranolol Treatment for Infantile Hemangiomas: Short-Term Adverse Effects and Follow-Up to Age Two.
Topics: Body Height; Body Weight; Central Nervous System; Child; Child, Preschool; Drug-Related Side Effects | 2019 |
Intolerable side effects during propranolol therapy for infantile hemangioma: frequency, risk factors and management.
Topics: Adrenergic beta-Antagonists; Drug-Related Side Effects and Adverse Reactions; Female; Hemangioma, Ca | 2018 |
Drug interactions in maternal intensive care: prevalence, risk factors, and potential risk medications.
Topics: Adolescent; Adult; Brazil; Cross-Sectional Studies; Diazepam; Drug Interactions; Drug-Related Side E | 2019 |
Practice gaps. Propranolol to treat hemangiomas of infancy: safety and side effect recognition.
Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Propranolol | 2013 |
The Role of the Pharmacist in the Treatment of Patients with Infantile Hemangioma Using Propranolol.
Topics: Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Hemangioma; H | 2016 |
When to stop propranolol for infantile hemangioma.
Topics: Administration, Oral; Antineoplastic Agents; Drug-Related Side Effects and Adverse Reactions; Female | 2017 |
Environmental risk assessment of six human pharmaceuticals: are the current environmental risk assessment procedures sufficient for the protection of the aquatic environment?
Topics: Animals; Carbamazepine; Clofibric Acid; Diclofenac; Drug-Related Side Effects and Adverse Reactions; | 2004 |
Toxic effect of pharmaceuticals on methanogenesis.
Topics: Bacteria, Anaerobic; Biomass; Carbamazepine; Clofibric Acid; Diclofenac; Drug-Related Side Effects a | 2004 |
On the effect of pharmaceuticals on bacterial nitrite oxidation.
Topics: Bacteria, Anaerobic; Biodegradation, Environmental; Bioreactors; Carbamazepine; Cities; Clofibrate; | 2004 |
Adverse drug reactions in the elderly: case studies.
Topics: Acetazolamide; Aged; Anemia, Hemolytic; Bromocriptine; Captopril; Chlorpropamide; Cimetidine; Clonid | 1984 |
Drug interactions and the prepared observer.
Topics: Cimetidine; Computers; Drug Information Services; Drug Interactions; Drug-Related Side Effects and A | 1981 |
Which patients may be harmed by good treatments?
Topics: Clinical Trials as Topic; Drug-Related Side Effects and Adverse Reactions; Humans; Myocardial Infarc | 1996 |
Xerostomia: prevalence and pharmacotherapy. With special reference to beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Amylases; Antihypertensive | 1996 |
Use of drugs in the aged.
Topics: Adolescent; Adult; Aged; Aging; Analgesics, Opioid; Benzodiazepines; Digoxin; Drug Therapy; Drug-Rel | 1979 |
Behavioral side effects of medical drugs.
Topics: Adrenal Cortex Hormones; Aged; Antihypertensive Agents; Antitubercular Agents; Aspirin; Behavior; Ca | 1979 |
[Drug side-effects in the lung].
Topics: Antineoplastic Agents; Asthma; Carbamazepine; Cromolyn Sodium; Drug-Related Side Effects and Adverse | 1978 |
Severe drug-induced hypoglycemia: a review.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; E | 1979 |
Adverse drug reactions.
Topics: Asthma; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Enzymes; Humans; Med | 1976 |
Lung disease caused by drugs.
Topics: Aspirin; Asthma; Contraceptives, Oral; Drug-Related Side Effects and Adverse Reactions; Eosinophilia | 1969 |
Interruption of a drug regimen before anesthesia.
Topics: Anesthesia; Anti-Infective Agents; Anticoagulants; Anticonvulsants; Antidepressive Agents; Antihyper | 1974 |
The management of patients taking drugs prior to anesthesia.
Topics: Adrenal Cortex Hormones; Antihypertensive Agents; Drug-Related Side Effects and Adverse Reactions; M | 1968 |