propranolol has been researched along with Adjuvant Arthritis in 7 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To examine this hypothesis, we induced mild and severe adjuvant arthritis (AA) in rats and daily doses of the NSAID, ketoprofen (KT), were given to half of these rats." | 7.69 | Influence of severity of inflammation on the disposition kinetics of propranolol enantiomers in ketoprofen-treated and untreated adjuvant arthritis. ( Jamali, F; Piquette-Miller, M, 1995) |
| " Kinetic parameters were derived from a two-phase physiologically based organ pharmacokinetic model." | 5.33 | Hepatic pharmacokinetics of propranolol in rats with adjuvant-induced systemic inflammation. ( Chang, P; Crawford, DH; Fletcher, L; Hung, DY; Roberts, MS; Siebert, GA; Whitehouse, MW, 2006) |
| " To examine this hypothesis, we induced mild and severe adjuvant arthritis (AA) in rats and daily doses of the NSAID, ketoprofen (KT), were given to half of these rats." | 3.69 | Influence of severity of inflammation on the disposition kinetics of propranolol enantiomers in ketoprofen-treated and untreated adjuvant arthritis. ( Jamali, F; Piquette-Miller, M, 1995) |
| " Experiment 2 showed that the suppression of adjuvant arthritis by exposure to the CS was blocked by administration of propranolol, a nonselective beta-adrenergic receptor antagonist." | 3.68 | Suppression of the development of adjuvant arthritis by a conditioned aversive stimulus. ( Luecken, LJ; Lysle, DT; Maslonek, KA, 1992) |
| " Kinetic parameters were derived from a two-phase physiologically based organ pharmacokinetic model." | 1.33 | Hepatic pharmacokinetics of propranolol in rats with adjuvant-induced systemic inflammation. ( Chang, P; Crawford, DH; Fletcher, L; Hung, DY; Roberts, MS; Siebert, GA; Whitehouse, MW, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawase, A | 1 |
| Ikuta, H | 1 |
| Uno, S | 1 |
| Yamamoto, K | 1 |
| Akitsu, N | 1 |
| Nagao, T | 1 |
| Iwaki, M | 1 |
| Guirguis, MS | 1 |
| Jamali, F | 3 |
| Hung, DY | 1 |
| Siebert, GA | 1 |
| Chang, P | 1 |
| Whitehouse, MW | 1 |
| Fletcher, L | 1 |
| Crawford, DH | 1 |
| Roberts, MS | 1 |
| Piquette-Miller, M | 2 |
| Rainsford, KD | 1 |
| Lysle, DT | 1 |
| Luecken, LJ | 1 |
| Maslonek, KA | 1 |
7 other studies available for propranolol and Adjuvant Arthritis
| Article | Year |
|---|---|
Alteration in plasma protein binding properties of propranolol and flurbiprofen during development of adjuvant-induced arthritis in rats.
Topics: Alkaline Phosphatase; Animals; Arthritis, Experimental; Aspartate Aminotransferases; Blood Proteins; | 2013 |
Disease-drug interaction: Reduced response to propranolol despite increased concentration in the rat with inflammation.
Topics: Adrenergic beta-Antagonists; Animals; Area Under Curve; Arthritis, Experimental; Calcium Channels; E | 2003 |
Hepatic pharmacokinetics of propranolol in rats with adjuvant-induced systemic inflammation.
Topics: Adrenergic beta-Antagonists; Alanine Transaminase; Algorithms; Alkaline Phosphatase; Animals; Arthri | 2006 |
Influence of severity of inflammation on the disposition kinetics of propranolol enantiomers in ketoprofen-treated and untreated adjuvant arthritis.
Topics: Animals; Arthritis, Experimental; Blood Proteins; Drug Interactions; Female; Inflammation; Ketoprofe | 1995 |
Selective effect of adjuvant arthritis on the disposition of propranolol enantiomers in rats detected using a stereospecific HPLC assay.
Topics: Administration, Oral; Animals; Arthritis, Experimental; Chromatography, High Pressure Liquid; Female | 1993 |
The role of aspirin in gastric ulceration . Some factors involved in the development of gastric mucosal damage induced by aspirin in rats exposed to various stress conditions.
Topics: Animals; Arthritis, Experimental; Aspirin; Atropine Derivatives; Bethanechol Compounds; Cold Tempera | 1978 |
Suppression of the development of adjuvant arthritis by a conditioned aversive stimulus.
Topics: Animals; Arthritis, Experimental; Avoidance Learning; Conditioning, Classical; Electroshock; Immune | 1992 |