Page last updated: 2024-11-03

propranolol and Adenocarcinoma

propranolol has been researched along with Adenocarcinoma in 13 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"Human gastric adenocarcinoma cell lines (SGC-7901 and BGC-823) were treated with or without propranolol and exposed to radiation."3.76Effects of propranolol in combination with radiation on apoptosis and survival of gastric cancer cells in vitro. ( Chaudhary, P; Che, X; Li, H; Liao, X; Long, H; Zhang, D; Zhao, W, 2010)
"The effects of combined administration of propranolol and tetragastrin on gastric acid secretion and the incidence and histological types of gastric adenocarcinomas induced by N-methyl-N'-nitro-N-nitrosoguanidine were investigated in inbred Wistar rats."3.67Enhancement by propranolol of the inhibitory effect of tetragastrin on gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. ( Iishi, H; Taniguchi, H; Tatsuta, M; Yamamura, H, 1987)
"Cell cultures of breast cancer cells were treated with beta-adrenergic agonists and antagonists, and changes in gene expression were determined by both relative competitive and real time PCR."1.32Expression of inwardly rectifying potassium channels (GIRKs) and beta-adrenergic regulation of breast cancer cell lines. ( Cakir, Y; Plummer, HK; Schuller, HM; Yu, Q, 2004)
"Lung cancer is the leading cause of cancer death in industrialized countries."1.31Beta-adrenergic modulation of NNK-induced lung carcinogenesis in hamsters. ( Porter, B; Riechert, A; Schuller, HM, 2000)
" Vasoactive drugs may therefore be of value to diminish adverse side effects of the combination cytostatic agent + DSM, probably decreasing overspill into normal tissues."1.28Reduction by norepinephrine of the side effects induced by combined hepatic arterial administration of degradable strach microspheres and adriamycin in rats with a liver adenocarcinoma. ( Jakobsson, B; Roos, G; Stenram, U; Teder, H, 1991)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coelho, M1
Moz, M1
Correia, G1
Teixeira, A1
Medeiros, R1
Ribeiro, L1
Shin, VY1
Jin, HC1
Ng, EK1
Yu, J1
Leung, WK1
Cho, CH1
Sung, JJ1
Liao, X2
Che, X2
Zhao, W2
Zhang, D2
Long, H1
Chaudhary, P1
Li, H1
Bi, T1
Wang, G1
Plummer, HK1
Yu, Q1
Cakir, Y1
Schuller, HM3
Porter, B1
Riechert, A1
Tutton, PJ1
Barkla, DH1
Jakobsson, B1
Teder, H1
Roos, G1
Stenram, U1
Cole, B1
Tatsuta, M2
Iishi, H2
Baba, M1
Mikuni, T1
Taniguchi, H2
Yamamura, H1
Gilman, AG1
Minna, JD1
Wade, H1

Other Studies

13 other studies available for propranolol and Adenocarcinoma

ArticleYear
Antiproliferative effects of β-blockers on human colorectal cancer cells.
    Oncology reports, 2015, Volume: 33, Issue:5

    Topics: Adenocarcinoma; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Atenolol; Carbazoles; Carvedi

2015
Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways.
    Toxicology and applied pharmacology, 2008, Dec-01, Volume: 233, Issue:2

    Topics: Adenocarcinoma; alpha7 Nicotinic Acetylcholine Receptor; Bungarotoxins; Carcinogens; Cell Line, Tumo

2008
Effects of propranolol in combination with radiation on apoptosis and survival of gastric cancer cells in vitro.
    Radiation oncology (London, England), 2010, Oct-26, Volume: 5

    Topics: Adenocarcinoma; Apoptosis; Biomarkers, Tumor; Blotting, Western; Cell Line, Tumor; Cell Separation;

2010
The β-adrenoceptor antagonist, propranolol, induces human gastric cancer cell apoptosis and cell cycle arrest via inhibiting nuclear factor κB signaling.
    Oncology reports, 2010, Volume: 24, Issue:6

    Topics: Adenocarcinoma; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Apoptosis; Cell Cycle; Cell L

2010
Expression of inwardly rectifying potassium channels (GIRKs) and beta-adrenergic regulation of breast cancer cell lines.
    BMC cancer, 2004, Dec-16, Volume: 4

    Topics: Adenocarcinoma; Adrenergic beta-Antagonists; Breast Neoplasms; Female; G Protein-Coupled Inwardly-Re

2004
Beta-adrenergic modulation of NNK-induced lung carcinogenesis in hamsters.
    Journal of cancer research and clinical oncology, 2000, Volume: 126, Issue:11

    Topics: Adenocarcinoma; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carcinogens; Criceti

2000
The influence of adrenoceptor activity on cell proliferation in colonic crypt ipithelium and in colonic adenocarcinomata.
    Virchows Archiv. B, Cell pathology, 1977, Jun-24, Volume: 24, Issue:2

    Topics: Adenocarcinoma; Animals; Cell Division; Colon; Colonic Neoplasms; Epinephrine; Epithelial Cells; Epi

1977
Reduction by norepinephrine of the side effects induced by combined hepatic arterial administration of degradable strach microspheres and adriamycin in rats with a liver adenocarcinoma.
    Selective cancer therapeutics, 1991,Fall, Volume: 7, Issue:3

    Topics: Adenocarcinoma; Animals; Doxorubicin; Hepatic Artery; Injections, Intra-Arterial; Liver; Liver Neopl

1991
Regulation of cell proliferation by beta-adrenergic receptors in a human lung adenocarcinoma cell line.
    Carcinogenesis, 1989, Volume: 10, Issue:9

    Topics: Adenocarcinoma; Cell Division; Cell Line; Hexamethonium; Hexamethonium Compounds; Humans; Lung Neopl

1989
Effects of propranolol and cimetidine on cysteamine inhibition of gastric carcinogenesis induced in Wistar rats by N-methyl-N'-nitro-N-nitrosoguanidine.
    International journal of cancer, 1989, Mar-15, Volume: 43, Issue:3

    Topics: Adenocarcinoma; Animals; Cimetidine; Cysteamine; Gastric Acid; Gastric Mucosa; Gastrins; Male; Methy

1989
Enhancement by propranolol of the inhibitory effect of tetragastrin on gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
    Cancer research, 1987, Jan-01, Volume: 47, Issue:1

    Topics: Adenocarcinoma; Animals; Drug Synergism; Gastric Acid; Gastric Mucosa; Gastrins; Hyperplasia; Male;

1987
Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in somatic cells. I. Responses to catecholamines in parental and hybrid cells.
    The Journal of biological chemistry, 1973, Oct-10, Volume: 248, Issue:19

    Topics: Adenocarcinoma; Animals; Cell Line; Chromosomes; Clone Cells; Cyclic AMP; Electrophoresis, Starch Ge

1973
The surgical management of thyroid disorders.
    Transactions of the Medical Society of London, 1972, Volume: 88

    Topics: Adenocarcinoma; Age Factors; Calcitonin; Carbimazole; Goiter; Humans; Hyperthyroidism; Neoplasm Meta

1972