propranolol has been researched along with Acute Kidney Injury in 43 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The half-life of total radioactivity is greatly lengthened in the presence of severe renal failure while the half-lives of the pharmacologically active propranolol and 4-hydroxymetabolite are slightly reduced." | 2.64 | Pharmacodynamics of propranolol in renal failure. ( Foulkes, DM; Joekes, AM; Thompson, FD, 1972) |
| "The aim of this study was to present a deductive compartment pharmacokinetic (PK) model to predict the concentration profiles of drugs in plasma and peritoneal fluid in peritoneal dialysis (PD) rats." | 1.40 | Effects of peritoneal dialysis on pharmacotherapy: a deductive pharmacokinetic-model approach to predict drug concentration profiles in plasma and peritoneal fluid. ( Aiba, T; Horiuchi, M; Kurosaki, Y; Moriyama, S; Takahata, Y, 2014) |
| "Diabetic nephropathy is the dominant cause of hypertension in insulin-dependent diabetics, and long-term rigid antihypertensive treatment inhibits the progression of nephropathy, probably even when there is renal insufficiency." | 1.28 | The effect of antihypertensive treatment on kidney function in insulin-dependent (type I) diabetics with renal failure. ( Conde, N; Gums, G; Heinke, P; Schulz, B; Strese, J; Zander, E; Zander, G, 1990) |
| "The effect of acute renal failure (ARF) on the pharmacokinetics of propranolol was investigated." | 1.27 | Increased availability of propranolol in rats with uranyl nitrate-induced acute renal failure. ( Fujiwara, J; Hori, R; Katayama, H; Okumura, K; Yasuhara, M, 1984) |
| " Pharmacokinetic studies were carried out on the fifth day after injection of the renal toxin (renal failure group) or saline (control group)." | 1.27 | Pharmacokinetics of l-propranolol during repetitive dosing in normal and uranyl nitrate-induced renal failure rats. ( Shen, DD; Terao, N, 1984) |
| " In contrast, acute uremia did elicit a change in the bioavailability of orally administered S(-)-propranolol." | 1.27 | Altered S(--)-propranolol disposition in bilateral ureter-ligated rats. ( Laganière, S; Shen, DD, 1987) |
| "The effect of uranyl nitrate-induced acute renal failure on the brain uptake of DL-propranolol was investigated in rats with a series of tissue-sampling single-carotid injection techniques." | 1.27 | Inhibition of blood-brain barrier permeability to DL-propranolol by serum from acute renal failure rats. ( Hanano, M; Iga, T; Lin, TH; Sawada, Y; Sugiyama, Y, 1987) |
| "The effect of acute renal failure (ARF) on the hepatic uptake and metabolism of propranolol was investigated in relation to the hepatic clearance of the drug." | 1.27 | Reduced hepatic uptake of propranolol in rats with acute renal failure. ( Hori, R; Katayama, H; Okumura, K; Yasuhara, M, 1985) |
| "Until recently acute renal failure in scleroderma has been uniformly fatal." | 1.26 | Medical treatment of hypertension and renal failure in scleroderma. ( Barnett, AJ, 1981) |
| "Warm ischemia is a potential problem during the harvesting of cadaveric kidneys for transplantation purposes." | 1.26 | Protective effect of propranolol in the treatment of ischemically damaged canine kidneys prior to transplantation. ( Emma, J; Khairallah, P; Loening, S; Magnusson, M; Ocon, J; Stowe, N; Straffon, R; Yarimizu, S, 1978) |
| "In this model of acute renal failure, renal vasoconstriction plays an important role following the initial ischemic insult." | 1.26 | Beneficial effect of propranolol in a histologically appropriate model of postischemic acute renal failure. ( D'Agostini, RJ; Freedman, MT; Heptinstall, RH; Scott, WW; Siegelman, SS; Solez, K; Stawowy, L, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (86.05) | 18.7374 |
| 1990's | 3 (6.98) | 18.2507 |
| 2000's | 1 (2.33) | 29.6817 |
| 2010's | 1 (2.33) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, V | 1 |
| Kumar, P | 1 |
| Verma, N | 1 |
| Vijayvergiya, R | 1 |
| Singh, A | 1 |
| Bhalla, A | 1 |
| Horiuchi, M | 1 |
| Moriyama, S | 1 |
| Takahata, Y | 1 |
| Aiba, T | 1 |
| Kurosaki, Y | 1 |
| Ozçakar, ZB | 1 |
| Yalçinkaya, F | 1 |
| Ensari, A | 1 |
| Kendirli, T | 1 |
| Ekim, M | 1 |
| Fitöz, S | 1 |
| Iaina, I | 1 |
| Serban, I | 2 |
| Gavendo, S | 3 |
| Kapuler, S | 2 |
| Eliahou, HE | 4 |
| Suzuki, Y | 1 |
| Ito, M | 1 |
| Komura, T | 1 |
| Riegel, W | 1 |
| Stepinski, J | 1 |
| Hörl, WH | 1 |
| Heidland, A | 1 |
| Katayama, H | 2 |
| Fujiwara, J | 1 |
| Yasuhara, M | 2 |
| Okumura, K | 2 |
| Hori, R | 2 |
| Terao, N | 3 |
| Shen, DD | 4 |
| Goldfarb, D | 1 |
| Iaina, A | 4 |
| Barnett, AJ | 1 |
| Bondia Román, A | 1 |
| Tabernero Romo, JM | 1 |
| Corbacho Becerra, I | 1 |
| Macias Núñez, JF | 1 |
| Rodríguez Commes, JL | 1 |
| Santiago Guervos, C | 1 |
| Esteban Fonseca, I | 1 |
| de Castro del Pozo, S | 1 |
| Fichtl, B | 1 |
| Gerdsmeier, W | 1 |
| Chevalier, RL | 1 |
| Finn, WF | 1 |
| Lee, YH | 2 |
| Ku, YS | 2 |
| Solomon, S | 3 |
| Eliahou, H | 1 |
| Moorthy, AV | 1 |
| Wu, MJ | 1 |
| Beirne, GJ | 1 |
| Sundstrom, WS | 1 |
| Solez, K | 2 |
| Freshwater, MF | 1 |
| Su, CT | 1 |
| Stowe, N | 1 |
| Emma, J | 1 |
| Magnusson, M | 1 |
| Loening, S | 1 |
| Yarimizu, S | 1 |
| Ocon, J | 1 |
| Khairallah, P | 1 |
| Straffon, R | 1 |
| Ortega, FJ | 1 |
| López-Novoa, JM | 1 |
| Rengel, MA | 1 |
| Hernando, L | 1 |
| Klein, LA | 1 |
| Mitnick, PD | 1 |
| Feig, PU | 1 |
| Trichet, B | 1 |
| Nebout, T | 1 |
| Guedon, J | 1 |
| Chapman, A | 1 |
| D'Agostini, RJ | 1 |
| Stawowy, L | 1 |
| Freedman, MT | 1 |
| Scott, WW | 1 |
| Siegelman, SS | 1 |
| Heptinstall, RH | 1 |
| Robert, M | 1 |
| Melita, P | 1 |
| Motta, A | 1 |
| Arsena, A | 1 |
| Calbo, L | 1 |
| Micali, C | 1 |
| De Leo, V | 1 |
| Zander, E | 1 |
| Conde, N | 1 |
| Heinke, P | 1 |
| Zander, G | 1 |
| Strese, J | 1 |
| Gums, G | 1 |
| Schulz, B | 1 |
| Laganière, S | 1 |
| Lin, TH | 1 |
| Sawada, Y | 1 |
| Sugiyama, Y | 1 |
| Iga, T | 1 |
| Hanano, M | 1 |
| Tiula, E | 1 |
| Haapanen, EJ | 1 |
| Neuvonen, PJ | 1 |
| Ishigami, M | 1 |
| Maeda, T | 1 |
| Yabuki, S | 1 |
| Stowe, NT | 1 |
| Thompson, FD | 2 |
| Joekes, AM | 2 |
| Fernandes, M | 1 |
| Kim, KE | 1 |
| Moyer, JH | 1 |
| Acchiardo, SR | 1 |
| Black, WD | 1 |
| Britt, L | 1 |
| McKeown, JW | 1 |
| Johnson, JG | 1 |
| Hatch, F | 1 |
| Hermreck, AS | 1 |
| Abrams, JH | 1 |
| Jones, RG | 1 |
| Cranston, WI | 1 |
| Foulkes, DM | 1 |
| Attar, S | 1 |
| Fardin, R | 1 |
| Ayella, R | 1 |
| McLaughlin, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites[NCT02649335] | Phase 3 | 190 participants (Actual) | Interventional | 2015-07-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for propranolol and Acute Kidney Injury
| Article | Year |
|---|---|
Hypertensive emergencies.
Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Antihypertensive Agents; Aortic Aneurysm; Blood Volume | 1974 |
Advances in medicine.
Topics: Acute Kidney Injury; Asthma; Blindness; Catecholamines; Contraceptives, Oral; Coronary Disease; Guan | 1968 |
2 trials available for propranolol and Acute Kidney Injury
| Article | Year |
|---|---|
Propranolol vs. band ligation for primary prophylaxis of variceal hemorrhage in cirrhotic patients with ascites: a randomized controlled trial.
Topics: Acute Kidney Injury; Ascites; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; L | 2022 |
Pharmacodynamics of propranolol in renal failure.
Topics: Acute Kidney Injury; Administration, Oral; Adult; Blood Pressure; Carbon Isotopes; Creatinine; Feces | 1972 |
39 other studies available for propranolol and Acute Kidney Injury
| Article | Year |
|---|---|
Effects of peritoneal dialysis on pharmacotherapy: a deductive pharmacokinetic-model approach to predict drug concentration profiles in plasma and peritoneal fluid.
Topics: Acute Kidney Injury; Animals; Ascitic Fluid; Cefazolin; Disease Models, Animal; Male; Models, Biolog | 2014 |
Thrombotic microangiopathy in a pediatric patient: question.
Topics: Acute Kidney Injury; Antihypertensive Agents; Biopsy; Child; Diagnosis, Differential; Enalapril; Fol | 2009 |
Alleviation of ischaemic acute renal failure by beta blockers: specific tubular receptor blockade or membrane stabilising effect?
Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Animals; Ischemia; Kidney; Kidney Tubules; Membran | 1980 |
[Pharmacological studies on the diuretic action of azosemide [5-(4'-chloro-5'-sulfamoyl-2'-thenylamino)-phenyltetrazole], a new diuretic (3). Effect of azosemide following pretreatment with SA-446, an angiotensin I converting enzyme inhibitor, or proprano
Topics: 3-Mercaptopropionic Acid; Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Diuretics; | 1982 |
Effect of hormones on hepatocyte gluconeogenesis in different models of acute uraemia.
Topics: Acute Kidney Injury; Animals; Blood Glucose; Bucladesine; Dihydroxyacetone; Disease Models, Animal; | 1982 |
Increased availability of propranolol in rats with uranyl nitrate-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Biological Availability; Intestinal Absorption; Kinetics; Liver; Liver | 1984 |
Pharmacokinetics of l-propranolol during repetitive dosing in normal and uranyl nitrate-induced renal failure rats.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Blood Proteins; Blood Urea Nitrogen; Injections, | 1984 |
Effect of experimental renal failure on the disposition kinetics of l-propranolol in rats.
Topics: Acute Kidney Injury; Animals; Biological Availability; Biotransformation; Blood Proteins; Blood Urea | 1983 |
Beneficial effect of verapamil in ischemic acute renal failure in the rat.
Topics: Acute Kidney Injury; Animals; Constriction; Creatinine; Female; Ischemia; Nephrectomy; Propranolol; | 1983 |
Medical treatment of hypertension and renal failure in scleroderma.
Topics: Acute Kidney Injury; Adult; Female; Humans; Hydralazine; Hypertension; Minoxidil; Propranolol; Scler | 1981 |
[Changes in the course of acute renal insufficiency by glycerol].
Topics: Acute Kidney Injury; Animals; Diuresis; Female; Glycerol; Male; Propranolol; Rats; Renin; Sodium Chl | 1980 |
Increased plasma protein binding of propranolol in rabbits with acute renal failure.
Topics: Acute Kidney Injury; Animals; Blood Proteins; Creatinine; Female; Glycerol; Male; Phenytoin; Propran | 1981 |
Effects of propranolol on post-ischemic acute renal failure.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Capillaries; Humans; Hydrostatic Pressure; Ischemia; K | 1980 |
Effects of propranolol on the pharmacokinetics of cyclosporine after intravenous and oral administration to control rats and rats with uranyl nitrate-induced acute renal failure.
Topics: Acute Kidney Injury; Administration, Oral; Adrenergic beta-Antagonists; Animals; Biliary Tract; Bloo | 1998 |
Effects of cyclosporin on the pharmacokinetics of propranolol after intravenous and oral administration to control rats and to rats with uranyl nitrate-induced acute renal failure.
Topics: Acute Kidney Injury; Administration, Oral; Adrenergic beta-Antagonists; Animals; Cyclosporine; Immun | 1999 |
beta-Adrenergic blockade reduces the severity of acute renal failure in rats.
Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Angiotensin II; Animals; Creatinine; Disease Model | 1976 |
Reduction in severity of acute renal failure in rats by beta-adrenergic blockade.
Topics: Acute Kidney Injury; Animals; Blood Specimen Collection; Creatinine; Disease Models, Animal; Drug Th | 1975 |
Control of hypertension with acute renal failure in scleroderma without nephrectomy.
Topics: Acute Kidney Injury; Humans; Hydralazine; Hypertension, Malignant; Male; Middle Aged; Propranolol; R | 1978 |
The effect of propranolol on postischemic acute renal failure in the rat.
Topics: Acute Kidney Injury; Animals; Ischemia; Kidney; Kidney Transplantation; Propranolol; Rats; Transplan | 1977 |
Protective effect of propranolol in the treatment of ischemically damaged canine kidneys prior to transplantation.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Dogs; Female; Ischemia; Kidney; Kidne | 1978 |
Effect of propranolol on glycerol induced acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Creatinine; Diuresis; Female; Glycerol; Injections, Intramuscular; Kid | 1978 |
Propranolol protection in acute renal failure.
Topics: Acute Kidney Injury; Angiotensins; Animals; Creatinine; Female; Kidney; Propranolol; Rats; Regional | 1978 |
Control of hypertension and reversal of renal failure in scleroderma.
Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Humans; Hydralazine; Hypertension, Malignant; M | 1978 |
Effect of high dose d-l propranolol on the renin-angiotensin system in glycerol induced acute renal failure in rat.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Glycerol; Male; Propranolol; Rats; Renin | 1978 |
Beneficial effect of propranolol in a histologically appropriate model of postischemic acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Drink | 1977 |
Alleviation of anoxic experimental acute renal failure in rats by beta-adrenergic blockade.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Dr | 1977 |
[Intensive care in the elderly patient. Clinical aspects (author's transl)].
Topics: Acute Kidney Injury; Aged; Dyspnea; Female; Humans; Intensive Care Units; Male; Micrognathism; Middl | 1977 |
[Use of mannitol and propranolol in the treatment of experimental acute renal failure (histomorphological study)].
Topics: Acute Kidney Injury; Animals; Dogs; Female; Kidney; Male; Mannitol; Propranolol | 1977 |
The effect of antihypertensive treatment on kidney function in insulin-dependent (type I) diabetics with renal failure.
Topics: Acute Kidney Injury; Antihypertensive Agents; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1; | 1990 |
Altered S(--)-propranolol disposition in bilateral ureter-ligated rats.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Blood Proteins; Injections, Intravenous; Intesti | 1987 |
Inhibition of blood-brain barrier permeability to DL-propranolol by serum from acute renal failure rats.
Topics: Acute Kidney Injury; Animals; Biological Transport; Blood Proteins; Blood-Brain Barrier; Brain; Cere | 1987 |
Factors affecting serum protein binding of phenytoin, diazepam and propranolol in acute renal diseases.
Topics: Acute Kidney Injury; Blood Proteins; Diazepam; Female; Humans; Male; Middle Aged; Phenytoin; Propran | 1987 |
The effects of d-propranolol and captopril on post-ischaemic acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Captopril; Drug Therapy, Combination; Male; Proline; Propranolol; Rats | 1985 |
Reduced extraction of I-propranolol by perfused rat liver in the presence of uremic blood.
Topics: Acute Kidney Injury; Animals; Blood Glucose; Blood Proteins; Kinetics; Liver; Male; Metabolic Cleara | 1985 |
Reduced hepatic uptake of propranolol in rats with acute renal failure.
Topics: Acute Kidney Injury; Animals; In Vitro Techniques; Liver; Male; Phenolsulfonphthalein; Propranolol; | 1985 |
Letter: Beta-blockade in the presence of renal disease and hypertension.
Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Humans; Hypertension; Kidney; Oxprenolol; Proprano | 1974 |
Experience with hemodialysis and renal transplantation in patients with malignant hypertension.
Topics: Acute Kidney Injury; Adult; Brain Diseases; Diazoxide; Diet Therapy; Female; Follow-Up Studies; Furo | 1974 |
Mannitol and propranolol in treatment of ischemic renal failure: improved survival rate and renal function.
Topics: Acute Kidney Injury; Animals; Dogs; Female; Ischemia; Kidney; Mannitol; Propranolol | 1973 |
Medical vs surgical treatment of acute dissecting aneurysms.
Topics: Acute Disease; Acute Kidney Injury; Adult; Aged; Aortic Aneurysm; Aortic Rupture; Aortography; Blood | 1971 |