Page last updated: 2024-11-03

propranolol and Active Hyperemia

propranolol has been researched along with Active Hyperemia in 34 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"9 kg; mean +/- SD) with arterial hypertension (WHO stages I and II) were administered single oral doses of placebo, 80 mg of propranolol, as well as 50 and 100 mg of brefanolol (a beta-adrenergic blocking agent with vasodilating properties) in order to determine the resulting hemodynamic effects."9.06Hemodynamic effects of brefanolol and propranolol assessed by noninvasive methods in patients with arterial hypertension. ( Endell, W; Halabi, A; Halabi, I; Kirch, W, 1990)
"Peak reactive hyperemia (mL."6.68Nonselective beta-adrenergic blockade with carvedilol does not hinder the benefits of exercise training in patients with congestive heart failure. ( Bijou, R; Demopoulos, L; Gentilucci, M; Jones, M; Katz, SD; LeJemtel, TH; Mancini, D; Testa, M; Yeh, M, 1997)
"Propranolol did not blunt postprandial hyperemia."6.67A randomized study of propranolol on postprandial portal hyperemia in cirrhotic patients. ( Albano, O; Buonamico, P; Ferraioli, G; Groszmann, RJ; Lerner, E; Mahl, T; Sabbá, C; Taylor, KJ, 1992)
"9 kg; mean +/- SD) with arterial hypertension (WHO stages I and II) were administered single oral doses of placebo, 80 mg of propranolol, as well as 50 and 100 mg of brefanolol (a beta-adrenergic blocking agent with vasodilating properties) in order to determine the resulting hemodynamic effects."5.06Hemodynamic effects of brefanolol and propranolol assessed by noninvasive methods in patients with arterial hypertension. ( Endell, W; Halabi, A; Halabi, I; Kirch, W, 1990)
"Peak reactive hyperemia (mL."2.68Nonselective beta-adrenergic blockade with carvedilol does not hinder the benefits of exercise training in patients with congestive heart failure. ( Bijou, R; Demopoulos, L; Gentilucci, M; Jones, M; Katz, SD; LeJemtel, TH; Mancini, D; Testa, M; Yeh, M, 1997)
"Propranolol did not blunt postprandial hyperemia."2.67A randomized study of propranolol on postprandial portal hyperemia in cirrhotic patients. ( Albano, O; Buonamico, P; Ferraioli, G; Groszmann, RJ; Lerner, E; Mahl, T; Sabbá, C; Taylor, KJ, 1992)
" A decline in mean arterial pressure was observed in both groups with increasing dosage of phentolamine."1.32Preserved alpha-adrenergic tone in the leg vascular bed of spinal cord-injured individuals. ( Hopman, MT; Kooijman, M; Rongen, GA; Smits, P, 2003)
"Hyperemia was elicited in the anesthetized rat anterior mesenteric artery after cessation of intravenous norepinephrine infusion at 0."1.29Multifactorial mediation of post norepinephrine induced intestinal hyperemia. ( Hottenstein, OD; Jacobson, ED; Remak, G, 1994)
"Pretreatment with prazosin (4 micrograms/kg/min i."1.28Beneficial effects of alpha 1-adrenoceptor activity on myocardial stunning in dogs. ( Gotoh, K; Hori, M; Inoue, M; Iwakura, K; Kamada, T; Kitabatake, A; Kitakaze, M; Sato, H, 1991)
"Hyperemia was quantitated from the peak vasodilation and from the area under the flow-hyperemia curve."1.27Vascular escape from vasoconstriction and post-stimulatory hyperemia in the superior mesenteric artery of the cat. ( Lautt, WW; Legare, DJ; Lockhart, LK, 1988)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199019 (55.88)18.7374
1990's9 (26.47)18.2507
2000's4 (11.76)29.6817
2010's2 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ross, AJ1
Gao, Z1
Pollock, JP1
Leuenberger, UA1
Sinoway, LI1
Muller, MD1
Crecelius, AR1
Kirby, BS1
Voyles, WF1
Dinenno, FA1
Kooijman, M1
Rongen, GA1
Smits, P1
Hopman, MT1
Kimiwada, T1
Kamii, H1
Tominaga, T1
Kato, M1
Pellinger, TK1
Halliwill, JR1
Thomas, M1
Gabe, I1
Mills, C1
Remak, G1
Hottenstein, OD2
Jacobson, ED2
Demopoulos, L1
Yeh, M1
Gentilucci, M1
Testa, M1
Bijou, R1
Katz, SD1
Mancini, D1
Jones, M1
LeJemtel, TH1
Sabbà, C2
Buonamico, P2
Vendemiale, G1
Berardi, E1
Antonica, G1
Palmieri, V1
Merkel, C1
Palasciano, G1
Schwartz, PJ1
Stone, HL1
Fasth, S1
Hultén, L1
Lundgren, O1
Nordgren, S1
Juhász-Nagy, A1
Urbanics, R1
Bache, RJ2
Cobb, FR2
Ebert, PA2
Greenfield, JC2
Sasaki, F1
Ishizaki, T1
Takahashi, H1
Ameshima, S1
Nakai, T1
Miyabo, S1
Ferraioli, G1
Mahl, T1
Taylor, KJ1
Lerner, E1
Albano, O1
Groszmann, RJ1
Yoshikawa, T1
Akaishi, M1
Ikeda, F1
Handa, S1
Nakamura, Y1
Goto, Y1
Slinker, BK1
LeWinter, MM1
Pawlik, WW1
Halabi, A1
Endell, W1
Halabi, I1
Kirch, W1
Kitakaze, M2
Hori, M2
Sato, H1
Iwakura, K2
Gotoh, K1
Inoue, M2
Kitabatake, A2
Kamada, T2
Novikova, EB1
Serebriakova, LI1
Tskitishvili, OV1
Tamai, J1
Koretsune, Y1
Kagiya, T1
Iwai, K1
Lautt, WW1
Legare, DJ1
Lockhart, LK1
Eikens, E2
Wilcken, DE2
Treister, G1
Bárány, EH1
Pauly, TJ2
Bittar, N2
Zarnstorff, WC1
Khouri, EM1
Gregg, DE2
Lowensohn, HS1
Winbury, MM1
Howe, BB1
Hefner, MA1
Yazaki, Y1
Kuramoto, K1
Fujii, J1
Murata, K1
Ikeda, M1
Grayson, J1
Irvine, M1
Parratt, JR1
Cunningham, J1
Pitt, B1
Rembert, JC1

Trials

5 trials available for propranolol and Active Hyperemia

ArticleYear
β-Adrenergic receptor blockade impairs coronary exercise hyperemia in young men but not older men.
    American journal of physiology. Heart and circulatory physiology, 2014, Nov-15, Volume: 307, Issue:10

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aging; Coronary Ves

2014
Nonselective beta-adrenergic blockade with carvedilol does not hinder the benefits of exercise training in patients with congestive heart failure.
    Circulation, 1997, Apr-01, Volume: 95, Issue:7

    Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Aerobiosis; Aged; Angiotensin-Converting Enz

1997
Haemodynamic effects of propranolol, octreotide and their combination during fasting and post-prandial splanchnic hyperaemia in patients with cirrhosis.
    European journal of gastroenterology & hepatology, 2001, Volume: 13, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Catheterization, Peripheral; Double-Blind M

2001
A randomized study of propranolol on postprandial portal hyperemia in cirrhotic patients.
    Gastroenterology, 1992, Volume: 102, Issue:3

    Topics: Female; Heart Rate; Humans; Hyperemia; Liver Circulation; Liver Cirrhosis; Male; Middle Aged; Portal

1992
Hemodynamic effects of brefanolol and propranolol assessed by noninvasive methods in patients with arterial hypertension.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:1

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Cardiac Output; Cardiography, Impedance; Ethanolamines;

1990

Other Studies

29 other studies available for propranolol and Active Hyperemia

ArticleYear
Augmented skeletal muscle hyperaemia during hypoxic exercise in humans is blunted by combined inhibition of nitric oxide and vasodilating prostaglandins.
    The Journal of physiology, 2011, Jul-15, Volume: 589, Issue:Pt 14

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Cyclooxygenase Inhibitors; Exercise; Fema

2011
Preserved alpha-adrenergic tone in the leg vascular bed of spinal cord-injured individuals.
    Circulation, 2003, Nov-11, Volume: 108, Issue:19

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cold Temperature;

2003
[A case of hyperemia during arteriovenous malformation surgery controlled with beta-blocker and jugular bulb oxygen saturation (SjO2) monitoring].
    Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Anesthesia, General; Brain Diseases; Humans; Hyperemia; Injectio

2003
Effect of propranolol on sympathetically mediated leg vasoconstriction in humans.
    The Journal of physiology, 2007, Sep-01, Volume: 583, Issue:Pt 2

    Topics: Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Blood Pressure; Epinephrine; Female; Femora

2007
Interpretation of the effects of propranolol on coronary reactive hyperaemia.
    European heart journal, 1983, Volume: 4, Issue:9

    Topics: Animals; Blood Volume; Coronary Circulation; Dogs; Hyperemia; Propranolol

1983
Multifactorial mediation of post norepinephrine induced intestinal hyperemia.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1994, Volume: 45, Issue:2

    Topics: Adenosine Deaminase; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists

1994
Tonic influence of the sympathetic nervous system on myocardial reactive hyperemia and on coronary blood flow distribution in dogs.
    Circulation research, 1977, Volume: 41, Issue:1

    Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Endocardium; Hemodynamics;

1977
Vascular responses to mechanical stimulation of the mucosa of the cat colon.
    Acta physiologica Scandinavica, 1977, Volume: 101, Issue:1

    Topics: Animals; Cats; Colon; Dihydroergotamine; Electric Stimulation; Hyperemia; Intestinal Mucosa; Pelvis;

1977
Influence of alpha- and beta-sympathetic blockade on hypoxic sensitivity of the coronaries.
    Japanese heart journal, 1976, Volume: 17, Issue:4

    Topics: Adaptation, Physiological; Animals; Coronary Circulation; Coronary Vessels; Dilatation; Dogs; Hypere

1976
Neurogenic influences on the coronary vascular response to ischemia in the awake dog.
    The Journal of thoracic and cardiovascular surgery, 1975, Volume: 69, Issue:3

    Topics: Animals; Autonomic Nervous System; Blood Pressure; Constriction; Coronary Circulation; Coronary Vess

1975
[Bronchial hyperresponsiveness to acetylcholine during acute pulmonary congestion in guinea pigs].
    Nihon Kyobu Shikkan Gakkai zasshi, 1992, Volume: 30, Issue:8

    Topics: Acetylcholine; Adrenergic beta-Antagonists; Airway Resistance; Animals; Bronchial Hyperreactivity; G

1992
Mechanisms of transient augmentation of myocardial contraction after a brief coronary occlusion.
    Japanese circulation journal, 1992, Volume: 56, Issue:4

    Topics: Animals; Calcium; Catecholamines; Constriction; Coronary Circulation; Coronary Disease; Dogs; Hemody

1992
Effect of coronary hyperemia on Emax and oxygen consumption in blood-perfused rabbit hearts. Energetic consequences of Gregg's phenomenon.
    Circulation research, 1991, Volume: 68, Issue:2

    Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Blood; Blood Pressure; Coronary Circulation; Energy

1991
Adrenergic modulation of reactive hyperemia in rat gut.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 1

    Topics: Adrenalectomy; Animals; Blood Pressure; Electric Stimulation; Hexamethonium; Hexamethonium Compounds

1991
Beneficial effects of alpha 1-adrenoceptor activity on myocardial stunning in dogs.
    Circulation research, 1991, Volume: 68, Issue:5

    Topics: Adenosine; Animals; Coronary Circulation; Dogs; Hyperemia; Methoxamine; Myocardial Contraction; Myoc

1991
[Effect of a decrease in perfusion pressure on the alpha-adrenergic reactions of the coronary vessels].
    Kardiologiia, 1988, Volume: 28, Issue:8

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Female; Hyperemia; Isoprotere

1988
Alpha 1-adrenoceptor activity regulates release of adenosine from the ischemic myocardium in dogs.
    Circulation research, 1987, Volume: 60, Issue:5

    Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Coronary Circulation; Dogs; Hyperemia; Ischemia; L

1987
Vascular escape from vasoconstriction and post-stimulatory hyperemia in the superior mesenteric artery of the cat.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:9

    Topics: Adenosine; Animals; Cats; Electric Stimulation; Female; Hyperemia; Male; Mesenteric Arteries; Norepi

1988
Myocardial reactive hyperemia and coronary vascular reactivity in the dog.
    Circulation research, 1973, Volume: 33, Issue:3

    Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Blood Pressure; Coronary Circu

1973
Proceedings: Reactive hyperaemia in the dog heart: assessment of post-hyperaemic coronary vascular reactivity and of the effects of temporarily restricting arterial inflow.
    The Journal of physiology, 1973, Volume: 234, Issue:2

    Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Heart; Hyperemia; Muscle, Smooth;

1973
Degeneration mydriasis and hyperemia of the iris after superior cervical ganglionectomy in the rabbit. Evidence for release of more than norepinephrine during degeneration of adrenergic terminals.
    Investigative ophthalmology, 1970, Volume: 9, Issue:11

    Topics: Accommodation, Ocular; Adrenergic alpha-Antagonists; Animals; Atropine; Bretylium Compounds; Chlorpr

1970
Myocardial reactive hyperaemia responses in the dog after beta receptor block with propranolol.
    Cardiovascular research, 1971, Volume: 5, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Blood Volume; Coronary Circulation; Coronary V

1971
Myocardial metabolic activity as a determinant of reactive hyperaemia responses in the dog heart.
    Cardiovascular research, 1973, Volume: 7, Issue:1

    Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Heart Rate; Hyperemia; Ligation; Myocardium; Ox

1973
Flow in the major branches of the left coronary artery during experimental coronary insufficiency in the unanesthetized dog.
    Circulation research, 1968, Volume: 23, Issue:1

    Topics: Animals; Arteries; Blood Flow Velocity; Collateral Circulation; Coronary Disease; Coronary Vessels;

1968
Effect of nitrates and other coronary dilators on large and small coronary vessels: an hypothesis for the mechanism of action of nitrates.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:1

    Topics: Aminophylline; Animals; Aorta; Biophysical Phenomena; Biophysics; Blood Circulation; Blood Flow Velo

1969
The effects of sympathetic nerves and catecholamines on the myocardial reactive hyperemia.
    Japanese circulation journal, 1970, Volume: 34, Issue:5

    Topics: Animals; Blood Pressure; Catecholamines; Coronary Disease; Coronary Vessels; Dogs; Electrocardiograp

1970
Vasospastic elements in myocardial infarction following coronary occlusion in the dog.
    Cardiovascular research, 1968, Volume: 2, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Blood Flow Velocity; Bretylium Compounds; Coronary Vessels; Dogs;

1968
Coronary hemodynamic effects of increasing ventricular rate in the unanesthetized dog.
    Circulation research, 1968, Volume: 22, Issue:6

    Topics: Animals; Aorta; Blood Circulation; Blood Pressure; Cardiac Output; Coronary Disease; Coronary Vessel

1968
Effects of beta-receptor blockade on the systemic and coronary hemodynamic response to an increasing ventricular rate in the unanesthetized dog.
    Circulation research, 1969, Volume: 25, Issue:3

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Coronary Vessels; Dogs; Heart Block; H

1969