propranolol has been researched along with Abnormality, Heart in 41 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "HRV was analysed in 14 infants with severe heart failure due to CHD who received a 'standard' therapy with digoxin and diuretics ('Digoxin/Diuretics' group) and in 9 of these patients with an additional propranolol therapy ('Propranolol' group) 17 days later on average and compared with HRV of 70 healthy infants ('Healthy Control')." | 9.10 | Heart rate variability in infants with heart failure due to congenital heart disease: reversal of depressed heart rate variability by propranolol. ( Buchhorn, R; Hulpke-Wette, M; Nothroff, J; Paul, T, 2002) |
| " After 17 days on average beta-blocker treated infants (propranolol:1,6 mg/kg/day) improved significantly with respect to Ross heart failure score (3." | 9.09 | Propranolol treatment of congestive heart failure in infants with congenital heart disease: The CHF-PRO-INFANT Trial. Congestive heart failure in infants treated with propanol. ( Bartmus, D; Buchhorn, R; Bürsch, J; Hilgers, R; Hulpke-Wette, M; Wessel, A, 2001) |
| "Infantile hemangiomas are the most common vascular tumors in childhood." | 5.42 | Delayed-onset of multiple cutaneous infantile hemangiomas due to propranolol: a case report. ( del Boz González, J; Navarro Morón, J; Porcel Chacón, R, 2015) |
| "HRV was analysed in 14 infants with severe heart failure due to CHD who received a 'standard' therapy with digoxin and diuretics ('Digoxin/Diuretics' group) and in 9 of these patients with an additional propranolol therapy ('Propranolol' group) 17 days later on average and compared with HRV of 70 healthy infants ('Healthy Control')." | 5.10 | Heart rate variability in infants with heart failure due to congenital heart disease: reversal of depressed heart rate variability by propranolol. ( Buchhorn, R; Hulpke-Wette, M; Nothroff, J; Paul, T, 2002) |
| " We compared the data from 8 infants with severe congestive heart failure due to left-to-right shunts, who received digoxin and diuretics alone, to 9 infants who received additional treatment with propranolol." | 5.10 | Effects of therapeutic beta blockade on myocardial function and cardiac remodelling in congenital cardiac disease. ( Buchhorn, R; Fielitz, J; Hetzer, R; Hulpke-Wette, M; Pregla, R; Regitz-Zagrosek, V; Ross, RD; Ruschewski, W, 2003) |
| " Beta-receptor gene expression in 16 children who received standard treatment for heart failure averaged lower than in the 10 children who received additional propranolol." | 5.10 | Beta-receptor downregulation in congenital heart disease: a risk factor for complications after surgical repair? ( Buchhorn, R; Fielitz, J; Hetzer, R; Hulpke-Wette, M; Pregla, R; Regitz-Zagrosek, V; Ruschewski, W, 2002) |
| " After 17 days on average beta-blocker treated infants (propranolol:1,6 mg/kg/day) improved significantly with respect to Ross heart failure score (3." | 5.09 | Propranolol treatment of congestive heart failure in infants with congenital heart disease: The CHF-PRO-INFANT Trial. Congestive heart failure in infants treated with propanol. ( Bartmus, D; Buchhorn, R; Bürsch, J; Hilgers, R; Hulpke-Wette, M; Wessel, A, 2001) |
| "We report on the clinical and neurohumoral effects of adding low-dose propranolol to conventional therapy with digoxin and diuretics in 6 infants with severe congestive heart failure due to large left-to-right shunts." | 3.70 | Beta-blocker therapy of severe congestive heart failure in infants with left to right shunts. ( Bartmus, D; Buchhorn, R; Bürsch, J; Hulpke-Wette, M; Schulz, R; Siekmeyer, W, 1998) |
| "Neonatal arrhythmias (NAs) are defined as abnormal heart rates in the neonatal period." | 1.43 | A case series of neonatal arrhythmias. ( Aydemir, O; Bas, AY; Celik, IH; Demirel, N; Isik, DU; Kavurt, S; Kibar, AE, 2016) |
| "Infantile hemangiomas are the most common vascular tumors in childhood." | 1.42 | Delayed-onset of multiple cutaneous infantile hemangiomas due to propranolol: a case report. ( del Boz González, J; Navarro Morón, J; Porcel Chacón, R, 2015) |
| "Recurrence was defined as documented SVT at >1 year of age." | 1.32 | Frequency of recurrence among infants with supraventricular tachycardia and comparison of recurrence rates among those with and without preexcitation and among those with and without response to digoxin and/or propranolol therapy. ( Fenrich, AL; Friedman, RA; Kertesz, NJ; Smith, EO; Snyder, CS; Tortoriello, TA, 2003) |
| "Verapamil was used in one infant with AV node reentry tachycardia." | 1.29 | Efficacy and risks of medical therapy for supraventricular tachycardia in neonates and infants. ( Saul, JP; Walsh, EP; Weindling, SN, 1996) |
| "Sinus node dysfunction is a recognized problem following surgery for congenital heart disease." | 1.28 | Electrophysiologic evaluation of sinus node dysfunction in postoperative children and young adults utilizing combined autonomic blockade. ( Garson, A; Gillette, PC; Marcus, B, 1991) |
| "No children have had recurrence of the arrhythmia after discontinuation of the drug." | 1.26 | Chaotic atrial tachycardia in childhood. ( Bisset, GS; Gaum, WE; Kaplan, S; Seigel, SF, 1981) |
| "Propranolol was injected into the yolk sac at doses ranging from 0." | 1.26 | The effect of propranolol upon chick embryo cardiogenesis. ( Gilani, SH; Silvestri, A, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (46.34) | 18.7374 |
| 1990's | 8 (19.51) | 18.2507 |
| 2000's | 8 (19.51) | 29.6817 |
| 2010's | 6 (14.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, L | 1 |
| Ng, A | 1 |
| Chen, W | 1 |
| Spencer, HT | 1 |
| Nguyen, J | 1 |
| Shen, AY | 1 |
| Lee, MS | 1 |
| Frongia, G | 1 |
| Byeon, JO | 1 |
| Arnold, R | 1 |
| Mehrabi, A | 1 |
| Günther, P | 1 |
| Moffett, BS | 1 |
| Lupo, PJ | 1 |
| delaUz, CM | 1 |
| Valdes, SO | 1 |
| Miyake, CY | 1 |
| Decker, JA | 1 |
| Kim, JJ | 1 |
| Porcel Chacón, R | 1 |
| del Boz González, J | 1 |
| Navarro Morón, J | 1 |
| You, HS | 1 |
| Kim, HS | 1 |
| Kim, BS | 1 |
| Kim, MB | 1 |
| Ko, HC | 1 |
| Isik, DU | 1 |
| Celik, IH | 1 |
| Kavurt, S | 1 |
| Aydemir, O | 1 |
| Kibar, AE | 1 |
| Bas, AY | 1 |
| Demirel, N | 1 |
| Buchhorn, R | 7 |
| Hulpke-Wette, M | 6 |
| Nothroff, J | 1 |
| Paul, T | 1 |
| Ruschewski, W | 2 |
| Ross, RD | 1 |
| Fielitz, J | 2 |
| Pregla, R | 2 |
| Hetzer, R | 2 |
| Regitz-Zagrosek, V | 2 |
| Tortoriello, TA | 1 |
| Snyder, CS | 1 |
| Smith, EO | 1 |
| Fenrich, AL | 1 |
| Friedman, RA | 1 |
| Kertesz, NJ | 1 |
| Peña, JJ | 1 |
| Marqués, JI | 1 |
| Mateo, E | 1 |
| Llagunes, J | 1 |
| Aguar, F | 1 |
| de Andrés, J | 1 |
| Palminiello, A | 1 |
| De Pinto, F | 1 |
| Di Eusanio, G | 1 |
| Di Tizio, S | 1 |
| Iacobone, G | 1 |
| Marcelletti, C | 1 |
| Massini, C | 1 |
| Piccoli, GP | 1 |
| Yabek, SM | 1 |
| Berman, W | 1 |
| Dillon, T | 1 |
| Riopel, DA | 1 |
| Walle, T | 1 |
| Bisset, GS | 1 |
| Seigel, SF | 1 |
| Gaum, WE | 1 |
| Kaplan, S | 1 |
| Kozlik-Feldmann, R | 1 |
| Kramer, HH | 1 |
| Wicht, H | 1 |
| Feldmann, R | 1 |
| Netz, H | 1 |
| Reinhardt, D | 1 |
| Tahernia, AC | 1 |
| Weindling, SN | 1 |
| Saul, JP | 1 |
| Walsh, EP | 1 |
| Bartmus, D | 2 |
| Siekmeyer, W | 1 |
| Schulz, R | 1 |
| Bürsch, J | 4 |
| Buheitel, G | 1 |
| Hofbeck, M | 1 |
| Leipold, G | 1 |
| Singer, H | 1 |
| Geesmann, M | 1 |
| Hilgers, R | 1 |
| Wessel, A | 2 |
| Werdan, K | 1 |
| Loppnow, H | 1 |
| Brévière, GM | 1 |
| Rey, C | 1 |
| Pernot, C | 1 |
| Dupuis, C | 1 |
| Gilani, SH | 1 |
| Silvestri, A | 1 |
| Sukumar, IP | 1 |
| Vijayaraghavan, G | 1 |
| Ostheimer, GW | 1 |
| Alper, MH | 1 |
| Hodach, RJ | 1 |
| Hodach, AE | 1 |
| Fallon, JF | 1 |
| Folts, JD | 1 |
| Bruyere, HJ | 1 |
| Gilbert, EF | 1 |
| Minkov, IP | 1 |
| Binder, LS | 1 |
| Boeche, R | 1 |
| Atkinson, D | 1 |
| Marcus, B | 1 |
| Gillette, PC | 1 |
| Garson, A | 1 |
| Hirsch, IA | 1 |
| Zauder, HL | 1 |
| Zerres, M | 1 |
| Meister, EM | 1 |
| Scheerschmidt, G | 1 |
| Bock, K | 1 |
| Loggie, JM | 1 |
| Van Maanen, EF | 1 |
| Viles, PH | 1 |
| Manning, JA | 1 |
| Paliev, B | 1 |
| Guneva, A | 1 |
| Marshall, CE | 1 |
| Shappell, SD | 1 |
| Giardina, AC | 1 |
| Ehlers, KH | 1 |
| Engle, MA | 1 |
| Levi, GF | 1 |
| Proto, C | 1 |
| List, WF | 1 |
| Marsoner, HJ | 1 |
| Kimura, N | 1 |
| Toshima, H | 1 |
| Nakakura, S | 1 |
| Sasaki, K | 1 |
| Mizunoe, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double Blind, Randomised, Placebo-controlled Study of Propranolol in Infantile Capillary Hemangiomas[NCT00744185] | Phase 2/Phase 3 | 14 participants (Actual) | Interventional | 2008-10-31 | Terminated (stopped due to Study halted prematurely due to some difficulties in recruitment of patients) | ||
| Intranasal Dexmedetomidine vs Oral Triclofos Sodium Sedation for Children With Autism Undergoing Electroencephalograms - A Randomized Controlled Trial.[NCT04270708] | Phase 4 | 200 participants (Anticipated) | Interventional | 2020-03-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for propranolol and Abnormality, Heart
| Article | Year |
|---|---|
[Cardiac surgery. Concepts and achievements in the past 10 years].
Topics: Anesthesia; Bioprosthesis; Cardiac Surgical Procedures; Coronary Artery Bypass; Coronary Care Units; | 1981 |
Cardiovascular anomalies in Marfan's syndrome: the role of echocardiography and beta-blockers.
Topics: Adolescent; Aortic Diseases; Auscultation; Child; Child, Preschool; Dilatation, Pathologic; Echocard | 1993 |
The autonomic nervous system and some aspects of the use of autonomic drugs in children. II.
Topics: Adrenergic beta-Antagonists; Aortic Valve Stenosis; Asthma; Autonomic Agents; Bronchitis; Cardiomyop | 1972 |
Recent advances in the treatment of congenital heart disease.
Topics: Age Factors; Arrhythmias, Cardiac; Child; Child, Preschool; Chlorothiazide; Diet, Sodium-Restricted; | 1974 |
5 trials available for propranolol and Abnormality, Heart
| Article | Year |
|---|---|
Heart rate variability in infants with heart failure due to congenital heart disease: reversal of depressed heart rate variability by propranolol.
Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Heart Defects, Congenital; Heart Failure; Heart Rate; Hemody | 2002 |
Effects of therapeutic beta blockade on myocardial function and cardiac remodelling in congenital cardiac disease.
Topics: Adrenergic beta-Antagonists; Digoxin; Diuretics; Dose-Response Relationship, Drug; Drug Administrati | 2003 |
Cardiovascular anomalies in Marfan's syndrome: the role of echocardiography and beta-blockers.
Topics: Adolescent; Aortic Diseases; Auscultation; Child; Child, Preschool; Dilatation, Pathologic; Echocard | 1993 |
Propranolol treatment of congestive heart failure in infants with congenital heart disease: The CHF-PRO-INFANT Trial. Congestive heart failure in infants treated with propanol.
Topics: Adrenergic beta-Antagonists; Cardiotonic Agents; Digoxin; Diuretics; Heart Defects, Congenital; Hear | 2001 |
Beta-receptor downregulation in congenital heart disease: a risk factor for complications after surgical repair?
Topics: Biopsy; Child, Preschool; Digoxin; Diuretics; Down-Regulation; Drug Therapy, Combination; Female; He | 2002 |
33 other studies available for propranolol and Abnormality, Heart
| Article | Year |
|---|---|
β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies.
Topics: Adrenergic beta-Antagonists; Age Factors; Arrhythmias, Cardiac; Atenolol; Body Mass Index; Californi | 2017 |
Cardiac diagnostics before oral propranolol therapy in infantile hemangioma: retrospective evaluation of 234 infants.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Cardiac Imaging Techniques; Cohort Studies; Echoc | 2018 |
Efficacy of digoxin in comparison with propranolol for treatment of infant supraventricular tachycardia: analysis of a large, national database.
Topics: Anti-Arrhythmia Agents; Databases as Topic; Digoxin; Female; Heart Defects, Congenital; Hospitalizat | 2015 |
Delayed-onset of multiple cutaneous infantile hemangiomas due to propranolol: a case report.
Topics: Dose-Response Relationship, Drug; Heart Defects, Congenital; Hemangioma; Humans; Infant; Infant, New | 2015 |
Propranolol to treat infantile hemangioma (IH) in patients with congenital heart disease.
Topics: Female; Heart Defects, Congenital; Hemangioma; Humans; Infant; Male; Propranolol; Prospective Studie | 2015 |
A case series of neonatal arrhythmias.
Topics: Adenosine; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Gestational Age; Heart Defects, Con | 2016 |
Frequency of recurrence among infants with supraventricular tachycardia and comparison of recurrence rates among those with and without preexcitation and among those with and without response to digoxin and/or propranolol therapy.
Topics: Age of Onset; Anti-Arrhythmia Agents; Digoxin; Female; Heart Defects, Congenital; Humans; Infant; In | 2003 |
[Perioperative management of a ruptured sinus of Valsalva aneurysm].
Topics: Anesthesia, General; Antithyroid Agents; Aortic Aneurysm; Aortic Rupture; Atrial Premature Complexes | 2008 |
Electrophysiologic effects of propranolol on sinus node function in children.
Topics: Adolescent; Cardiac Catheterization; Child; Child, Preschool; Electrocardiography; Electrophysiology | 1982 |
Kinetic and clinical observations in cyanotic children on propranolol therapy.
Topics: Child; Child, Preschool; Dose-Response Relationship, Drug; Half-Life; Heart Defects, Congenital; Hea | 1980 |
Chaotic atrial tachycardia in childhood.
Topics: Adolescent; Arrhythmias, Cardiac; Child; Child, Preschool; Chronic Disease; Digoxin; Electrocardiogr | 1981 |
Distribution of myocardial beta-adrenoceptor subtypes and coupling to the adenylate cyclase in children with congenital heart disease and implications for treatment.
Topics: Adenylyl Cyclases; Adolescent; Animals; Child; Child, Preschool; Down-Regulation; Heart Atria; Heart | 1993 |
Efficacy and risks of medical therapy for supraventricular tachycardia in neonates and infants.
Topics: Anti-Arrhythmia Agents; Catheter Ablation; Digoxin; Electrocardiography; Esophagus; Female; Follow-U | 1996 |
Beta-blocker therapy of severe congestive heart failure in infants with left to right shunts.
Topics: Adrenergic beta-Antagonists; Child, Preschool; Combined Modality Therapy; Female; Follow-Up Studies; | 1998 |
[Incidence and treatment of reactive infundibular obstruction after balloon dilatation of critical pulmonary valve stenoses].
Topics: Angiography; Catheterization; Echocardiography; Female; Follow-Up Studies; Heart Defects, Congenital | 1999 |
[Electrocardiographic signs of autonomic imbalance in infants with congenital heart defects].
Topics: Age Factors; Cardiotonic Agents; Data Interpretation, Statistical; Digoxin; Diuretics; Electrocardio | 2001 |
Endogenous nitric oxide and soluble tumor necrosis factor receptor levels are enhanced in infants with congenital heart disease.
Topics: Adrenergic beta-Antagonists; Enzyme-Linked Immunosorbent Assay; Heart Defects, Congenital; Heart Fai | 2001 |
[Major hypoglycemic complications in children treated by beta blockaders].
Topics: Adrenergic beta-Antagonists; Child, Preschool; Female; Heart Defects, Congenital; Humans; Hypoglycem | 1978 |
The effect of propranolol upon chick embryo cardiogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Dose-Response Relationship, Drug; Heart; Heart D | 1977 |
Medical management of congenital cyanotic heart disease.
Topics: Anemia; Child; Child, Preschool; Cyanosis; Heart Defects, Congenital; Hemoptysis; Humans; Infant; In | 1976 |
Intrapartum anesthetic management of the pregnant patient with heart disease.
Topics: Anesthesia, Epidural; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Local; Anesthesia, Ob | 1975 |
The role of beta-adrenergic activity in the production of cardiac and aortic arch anomalies in chick embryos.
Topics: Abnormalities, Drug-Induced; Animals; Aorta; Chick Embryo; Ductus Arteriosus, Patent; Epinephrine; H | 1975 |
[Erythrocyte membranes in patients with congenital cyanotic heart disease before and after obsidan therapy].
Topics: Child, Preschool; Cyanosis; Erythrocyte Membrane; Fatty Acids; Heart Defects, Congenital; Humans; Me | 1991 |
Evaluation and management of supraventricular tachycardia in children.
Topics: Anemia; Dehydration; Dopamine; Electric Countershock; Fluid Therapy; Heart Defects, Congenital; Huma | 1991 |
Electrophysiologic evaluation of sinus node dysfunction in postoperative children and young adults utilizing combined autonomic blockade.
Topics: Adolescent; Adult; Arrhythmia, Sinus; Atropine; Autonomic Nervous System; Child; Child, Preschool; E | 1991 |
Chloral hydrate: a potential cause of arrhythmias.
Topics: Child; Child, Preschool; Chloral Hydrate; Digoxin; Female; Heart Defects, Congenital; Humans; Infant | 1986 |
[Acidosis in heart abnormalities eith right-left shunt in childhood].
Topics: Acidosis; Adolescent; Adrenergic beta-Antagonists; Bicarbonates; Child; Child, Preschool; Heart Defe | 1971 |
[Clinical significance of the inderal (propranolol) test].
Topics: Adolescent; Adult; Electrocardiography; Heart Defects, Congenital; Heart Ventricles; Humans; Propran | 1973 |
Sudden death and the ballooning posterior leaflet syndrome. Detailed anatomic and histochemical investigation.
Topics: Adult; Aorta; Autopsy; Coronary Vessels; Death, Sudden; Electrocardiography; Female; Heart Auscultat | 1974 |
Wolff-Parkinson-White syndrome in infants and children. A long-term follow-up study.
Topics: Adolescent; Adult; Child; Child, Preschool; Digitalis Glycosides; Electrocardiography; Female; Follo | 1972 |
Combined treatment of atrial fibrillation with propranolol and quinidine.
Topics: Atrial Fibrillation; Coronary Disease; Drug Interactions; Female; Heart Defects, Congenital; Heart V | 1970 |
[Experiences with propranolol during and after surgical interventions on the heart].
Topics: Adolescent; Adult; Anesthesia, General; Cardiac Surgical Procedures; Child; Child, Preschool; Depres | 1968 |
Hemodynamic effects of beta-adrenergic blockade in patients with congenital heart disease.
Topics: Adolescent; Adult; Angiocardiography; Blood Pressure; Cardiac Catheterization; Child; Child, Prescho | 1968 |