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propranolol and Abdominal Aortic Aneurysm

propranolol has been researched along with Abdominal Aortic Aneurysm in 11 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
" We investigated whether propranolol decreases the growth rate of small abdominal aortic aneurysms (AAAs)."9.10Propranolol for small abdominal aortic aneurysms: results of a randomized trial. ( , 2002)
"To study the propranolol treatment of small abdominal aortic aneurysms (AAA) concerning intention to treat, side effects, and inhibition of expansion."9.09Impaired results of a randomised double blinded clinical trial of propranolol versus placebo on the expansion rate of small abdominal aortic aneurysms. ( Fasting, H; Henneberg, EW; Juul, S; Lindholt, JS, 1999)
"Propranolol has been suggested to slow aortic aneurysm (AAA) expansion by a mechanism independent of simple blood pressure (BP) reduction."5.29Effects of hypertension and propranolol upon aneurysm expansion in the Anidjar/Dobrin aneurysm model. ( Gadowski, GR; Hendley, ED; Nichols, P; Pilcher, DB; Ricci, MA; Slaiby, JM, 1996)
" We investigated whether propranolol decreases the growth rate of small abdominal aortic aneurysms (AAAs)."5.10Propranolol for small abdominal aortic aneurysms: results of a randomized trial. ( , 2002)
"To study the propranolol treatment of small abdominal aortic aneurysms (AAA) concerning intention to treat, side effects, and inhibition of expansion."5.09Impaired results of a randomised double blinded clinical trial of propranolol versus placebo on the expansion rate of small abdominal aortic aneurysms. ( Fasting, H; Henneberg, EW; Juul, S; Lindholt, JS, 1999)
" Using a mail survey, we elicited the MID of different physician specialties (family medicine, internal medicine, vascular surgery) for using propranolol to slow abdominal aortic aneurysm (AAA) growth assuming that propranolol was efficacious in this condition."3.70Surveying physicians to determine the minimal important difference: implications for sample-size calculation. ( Bohm, C; Laupacis, A; Mahon, JL; Moher, D; van Walraven, C, 1999)
"Propranolol was poorly tolerated by patients in all of the beta-blocker trials and demonstrated only minimal and non-significant protective effects."2.48Medical treatment for small abdominal aortic aneurysms. ( Clarke, M; Robertson, L; Rughani, G, 2012)
"Abdominal aortic aneurysm is a common condition that may be lethal when it is unrecognized."2.44Medical management of small abdominal aortic aneurysms. ( Baxter, BT; Dalman, RL; Terrin, MC, 2008)
"A propranolol dose-response was studied for each strain: (1) saline solution controls (n = 18); (2) propranolol, 10 mg/kg subcutaneously (n = 18); (3) propranolol, 30 mg/kg (n = 14)."1.29Expansion of aortic aneurysms is reduced by propranolol in a hypertensive rat model. ( Gadowski, GR; Hendley, ED; Pilcher, DB; Ricci, MA; Slaiby, JM, 1994)
"Propranolol has been suggested to slow aortic aneurysm (AAA) expansion by a mechanism independent of simple blood pressure (BP) reduction."1.29Effects of hypertension and propranolol upon aneurysm expansion in the Anidjar/Dobrin aneurysm model. ( Gadowski, GR; Hendley, ED; Nichols, P; Pilcher, DB; Ricci, MA; Slaiby, JM, 1996)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (63.64)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Assar, AN1
Rughani, G1
Robertson, L1
Clarke, M1
Baxter, BT1
Terrin, MC1
Dalman, RL1
Slaiby, JM2
Ricci, MA3
Gadowski, GR2
Hendley, ED2
Pilcher, DB3
Mellière, D1
Cronenwett, JL1
Nichols, P1
McBride, R1
Lindholt, JS1
Henneberg, EW1
Juul, S1
Fasting, H1
van Walraven, C1
Mahon, JL1
Moher, D1
Bohm, C1
Laupacis, A1

Reviews

5 reviews available for propranolol and Abdominal Aortic Aneurysm

ArticleYear
Medical treatment of small abdominal aortic aneurysm.
    The Journal of cardiovascular surgery, 2012, Volume: 53, Issue:4

    Topics: Aortic Aneurysm, Abdominal; Cardiovascular Agents; Disease Progression; Doxycycline; Humans; Hydroxy

2012
Medical treatment for small abdominal aortic aneurysms.
    The Cochrane database of systematic reviews, 2012, Sep-12, Issue:9

    Topics: Adrenergic beta-Antagonists; Anti-Bacterial Agents; Aortic Aneurysm, Abdominal; Azithromycin; Doxycy

2012
Medical management of small abdominal aortic aneurysms.
    Circulation, 2008, Apr-08, Volume: 117, Issue:14

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2008
[Asymptomatic aneurysms of the abdominal aorta: in whom are they detected? When should a beta-blocker be prescribed? Who should have surgery and by which technique?].
    Journal des maladies vasculaires, 1995, Volume: 20, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aneurysm, Ruptured; Aortic Aneurysm, Abdominal

1995
Variables that affect the expansion rate and rupture of abdominal aortic aneurysms.
    Annals of the New York Academy of Sciences, 1996, Nov-18, Volume: 800

    Topics: Adrenergic beta-Antagonists; Aortic Aneurysm, Abdominal; Aortic Rupture; Comorbidity; Diastole; Dise

1996

Trials

3 trials available for propranolol and Abdominal Aortic Aneurysm

ArticleYear
Design of a trial to evaluate the effect of propranolol upon abdominal aortic aneurysm expansion.
    Annals of the New York Academy of Sciences, 1996, Nov-18, Volume: 800

    Topics: Adrenergic beta-Antagonists; Aortic Aneurysm, Abdominal; Aortic Rupture; Disease Progression; Double

1996
Impaired results of a randomised double blinded clinical trial of propranolol versus placebo on the expansion rate of small abdominal aortic aneurysms.
    International angiology : a journal of the International Union of Angiology, 1999, Volume: 18, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aortic Aneurysm, Abdominal; Double-Blind Method; Dyspnea; Humans;

1999
Propranolol for small abdominal aortic aneurysms: results of a randomized trial.
    Journal of vascular surgery, 2002, Volume: 35, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Double-Blind Method

2002

Other Studies

3 other studies available for propranolol and Abdominal Aortic Aneurysm

ArticleYear
Expansion of aortic aneurysms is reduced by propranolol in a hypertensive rat model.
    Journal of vascular surgery, 1994, Volume: 20, Issue:2

    Topics: Analysis of Variance; Animals; Aortic Aneurysm, Abdominal; Dose-Response Relationship, Drug; Female;

1994
Effects of hypertension and propranolol upon aneurysm expansion in the Anidjar/Dobrin aneurysm model.
    Annals of the New York Academy of Sciences, 1996, Nov-18, Volume: 800

    Topics: Adrenergic beta-Antagonists; Aged; Animals; Antihypertensive Agents; Aortic Aneurysm, Abdominal; Aor

1996
Surveying physicians to determine the minimal important difference: implications for sample-size calculation.
    Journal of clinical epidemiology, 1999, Volume: 52, Issue:8

    Topics: Adrenergic beta-Antagonists; Aortic Aneurysm, Abdominal; Attitude of Health Personnel; Data Collecti

1999