propofol has been researched along with Ventricular Dysfunction, Left in 18 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results of this trial suggest that a propofol-based anesthetic, when compared to an enflurane-based anesthetic requiring additional dosing of fentanyl and midazolam for CPB, can lead to a significant reduction in time to extubation after CABG surgery, without adverse hemodynamic effects, increased risk of myocardial ischemia or infarction." | 6.68 | Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery. ( Buckland, MR; Bujor, MA; Davis, BB; Hunt, JO; Langley, M; McRae, R; Moloney, JT; Myles, PS; Weeks, AM, 1997) |
| "Cardiac sarcoidosis is characterized by a high incidence of complete atrioventricular block, ventricular arrhythmia, and cardiac dysfunction." | 5.36 | [Total intravenous anesthesia for a patient with cardiac sarcoidosis associated with left ventricular dysfunction using remifentanil and propofol]. ( Kawamoto, M; Kusunoki, S; Miyoshi, H, 2010) |
| "Propofol was administered using CLADS or TCI for maintaining BIS of 50." | 2.84 | Anaesthetic depth control using closed loop anaesthesia delivery system vs. target controlled infusion in patients with moderate to severe left ventricular systolic dysfunction. ( Mahajan, V; Puri, GD; Samra, T, 2017) |
| "Propofol has antioxidant properties which may attenuate such a response." | 2.72 | The effects of propofol on neutrophil function, lipid peroxidation and inflammatory response during elective coronary artery bypass grafting in patients with impaired ventricular function. ( Corcoran, TB; Engel, A; O'Callaghan-Enright, S; O'Shea, A; Sakamoto, H; Shorten, GD, 2006) |
| "Propofol was used as TCI (plasma target concentration, 2 to 3 microg x mL; n = 10) or MCI (2." | 2.70 | Target-controlled infusion or manually controlled infusion of propofol in high-risk patients with severely reduced left ventricular function. ( Boldt, J; Kumle, B; Lehmann, A; Römpert, R; Thaler, E; Weisse, U, 2001) |
| " The results of this trial suggest that a propofol-based anesthetic, when compared to an enflurane-based anesthetic requiring additional dosing of fentanyl and midazolam for CPB, can lead to a significant reduction in time to extubation after CABG surgery, without adverse hemodynamic effects, increased risk of myocardial ischemia or infarction." | 2.68 | Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery. ( Buckland, MR; Bujor, MA; Davis, BB; Hunt, JO; Langley, M; McRae, R; Moloney, JT; Myles, PS; Weeks, AM, 1997) |
| "Ketamine has a favorable cardiovascular profile related to central sympathetic stimulation and inhibition of neuronal catecholamine uptake." | 2.43 | Intravenous anesthesia for the patient with left ventricular dysfunction. ( Bovill, JG, 2006) |
| "Cardiac sarcoidosis is characterized by a high incidence of complete atrioventricular block, ventricular arrhythmia, and cardiac dysfunction." | 1.36 | [Total intravenous anesthesia for a patient with cardiac sarcoidosis associated with left ventricular dysfunction using remifentanil and propofol]. ( Kawamoto, M; Kusunoki, S; Miyoshi, H, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahajan, V | 1 |
| Samra, T | 1 |
| Puri, GD | 1 |
| Soleimani, A | 1 |
| Heidari, N | 1 |
| Habibi, MR | 1 |
| Kiabi, FH | 1 |
| Khademloo, M | 1 |
| Emami Zeydi, A | 1 |
| Sohrabi, FB | 1 |
| Matsuda, H | 1 |
| Arai, M | 1 |
| Okamoto, H | 1 |
| Keyl, C | 1 |
| Trenk, D | 1 |
| Laule, S | 1 |
| Schuppe, C | 1 |
| Staier, K | 1 |
| Wiesenack, C | 1 |
| Albiez, G | 1 |
| Yildirim, V | 1 |
| Doganci, S | 1 |
| Aydin, A | 1 |
| Bolcal, C | 1 |
| Demirkilic, U | 1 |
| Cosar, A | 1 |
| Torigoe, K | 1 |
| Suzuki, H | 1 |
| Nakajima, W | 1 |
| Takahashi, M | 1 |
| Aoyagi, M | 1 |
| Miyoshi, H | 1 |
| Kusunoki, S | 1 |
| Kawamoto, M | 1 |
| Seehase, M | 1 |
| Houthuizen, P | 1 |
| Jellema, RK | 1 |
| Collins, JJ | 1 |
| Bekers, O | 1 |
| Breuer, J | 1 |
| Kramer, BW | 1 |
| Kulkarni, A | 1 |
| Price, G | 1 |
| Saxena, M | 1 |
| Skowronski, G | 1 |
| Bovill, JG | 1 |
| Corcoran, TB | 1 |
| Engel, A | 1 |
| Sakamoto, H | 1 |
| O'Shea, A | 1 |
| O'Callaghan-Enright, S | 1 |
| Shorten, GD | 1 |
| Filipovic, M | 1 |
| Michaux, I | 1 |
| Wang, J | 1 |
| Hunziker, P | 1 |
| Skarvan, K | 1 |
| Seeberger, M | 1 |
| Guarracino, F | 1 |
| Oppizzi, M | 1 |
| Benussi, S | 1 |
| Triggiani, M | 1 |
| Paolillo, G | 1 |
| Myles, PS | 2 |
| Buckland, MR | 1 |
| Weeks, AM | 1 |
| Bujor, MA | 1 |
| McRae, R | 1 |
| Langley, M | 1 |
| Moloney, JT | 1 |
| Hunt, JO | 1 |
| Davis, BB | 1 |
| Lehmann, A | 2 |
| Boldt, J | 2 |
| Zeitler, C | 1 |
| Thaler, E | 2 |
| Werling, C | 1 |
| Leonard, IE | 1 |
| Römpert, R | 1 |
| Kumle, B | 1 |
| Weisse, U | 1 |
| Gare, M | 1 |
| Parail, A | 1 |
| Milosavljevic, D | 1 |
| Kersten, JR | 1 |
| Warltier, DC | 1 |
| Pagel, PS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of the Efficiency of Anesthetic Depth Control Using Closed Loop Anesthesia Delivery System vs. Manual Control Using Target Controlled Infusion in Patients With Moderate to Severe Left Ventricular Systolic Dysfunction[NCT02645994] | 40 participants (Actual) | Interventional | 2014-07-31 | Completed | |||
| Anesthesia for Upper Endoscopy and Colonoscopy in Cardiac Patients With Acute Anemia: Pretreatment With Low-dose Ketamine Can Reduce the Dose of Etomidate. A Randomized Clinical Trial.[NCT04857450] | 60 participants (Anticipated) | Interventional | 2020-11-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for propofol and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Intravenous anesthesia for the patient with left ventricular dysfunction.
Topics: Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Intravenous; Etomidate; Humans; Ket | 2006 |
9 trials available for propofol and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Anaesthetic depth control using closed loop anaesthesia delivery system vs. target controlled infusion in patients with moderate to severe left ventricular systolic dysfunction.
Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Cardiac Surgical Procedures; Conscio | 2017 |
Comparing Hemodynamic Responses to Diazepam, Propofol and Etomidate During Anesthesia Induction in Patients with Left Ventricular Dysfunction Undergoing Coronary Artery Bypass Graft Surgery: a Double-blind, Randomized Clinical Trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Coronary Artery Bypass; Diazepam; Double-B | 2017 |
Predicted and measured plasma propofol concentration and bispectral index during deep sedation in patients with impaired left ventricular function.
Topics: Aged; Blood Gas Analysis; Chromatography, High Pressure Liquid; Cohort Studies; Deep Sedation; Defib | 2009 |
Cardioprotective effects of sevoflurane, isoflurane, and propofol in coronary surgery patients: a randomized controlled study.
Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Cardiotonic Agents; Coronary Artery Bypas | 2009 |
The effects of propofol on neutrophil function, lipid peroxidation and inflammatory response during elective coronary artery bypass grafting in patients with impaired ventricular function.
Topics: Aged; Anesthetics, Intravenous; Coronary Artery Bypass; Female; Humans; Inflammation Mediators; Inte | 2006 |
Effects of sevoflurane and propofol on left ventricular diastolic function in patients with pre-existing diastolic dysfunction.
Topics: Adult; Aged; Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Aortic Valve S | 2007 |
Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery.
Topics: Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Coronary Artery Bypass; Enflura | 1997 |
Target-controlled infusion or manually controlled infusion of propofol in high-risk patients with severely reduced left ventricular function.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Defibrillators, Implantable; Female; Hemodynamics | 2001 |
Conscious sedation with midazolam or propofol does not alter left ventricular diastolic performance in patients with preexisting diastolic dysfunction: a transmitral and tissue Doppler transthoracic echocardiography study.
Topics: Adult; Diastole; Double-Blind Method; Echocardiography; Female; Heart Rate; Hemodynamics; Humans; Hy | 2001 |
8 other studies available for propofol and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
[Total intravenous anesthesia for a patient with Fukuyama congenital muscular dystrophy undergoing scoliosis surgery].
Topics: Adolescent; Anesthesia, Intravenous; Humans; Lung Diseases, Obstructive; Male; Monitoring, Intraoper | 2014 |
[Anesthetic management using esmolol for arthroscopic synovectomy in a patient with thyroid storm].
Topics: Adrenergic beta-Antagonists; Anesthesia, Intravenous; Antithyroid Agents; Arthritis, Infectious; Art | 2010 |
[Total intravenous anesthesia for a patient with cardiac sarcoidosis associated with left ventricular dysfunction using remifentanil and propofol].
Topics: Aged, 80 and over; Anesthesia, Intravenous; Cardiomyopathies; Colectomy; Hepatectomy; Humans; Male; | 2010 |
Propofol administration to the fetal-maternal unit reduces cardiac injury in late-preterm lambs subjected to severe prenatal asphyxia and cardiac arrest.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Animals, Newborn; Asphyxia Neonatorum; B | 2013 |
Difficult extubation: calming the sympathetic storm.
Topics: Aged; Conscious Sedation; Device Removal; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedat | 2004 |
Negative inotropic effect of low-dose propofol infusion in cardiac-compromised patients.
Topics: Anesthetics, Intravenous; Depression, Chemical; Female; Humans; Male; Middle Aged; Myocardial Contra | 1996 |
Total intravenous anesthesia with remifentanil and propofol for implantation of cardioverter-defibrillators in patients with severely reduced left ventricular function.
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Arrhythmias, Cardiac | 1999 |
Target-controlled intravenous anaesthesia with bispectral index monitoring for thoracotomy in a patient with severely impaired left ventricular function.
Topics: Aged; Analgesia, Epidural; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intrave | 2000 |