propofol has been researched along with Uremia in 2 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacokinetic variables were similar in uraemic and control patients; mean elimination half-lives were 1638 (SD 340) min and 1714 (842) min, respectively." | 1.28 | Pharmacokinetics of propofol and haemodynamic changes during induction of anaesthesia in uraemic patients. ( Kirvelä, M; Lindgren, L; Olkkola, KT; Rosenberg, PH; Salmela, K; Yli-Hankala, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lewis, IH | 1 |
| Sneyd, R | 1 |
| Kirvelä, M | 1 |
| Olkkola, KT | 1 |
| Rosenberg, PH | 1 |
| Yli-Hankala, A | 1 |
| Salmela, K | 1 |
| Lindgren, L | 1 |
2 other studies available for propofol and Uremia
| Article | Year |
|---|---|
Propofol in uraemic patients.
Topics: Anesthesia, General; Contraindications; Hemodynamics; Humans; Propofol; Uremia | 1992 |
Pharmacokinetics of propofol and haemodynamic changes during induction of anaesthesia in uraemic patients.
Topics: Adult; Aged; Anesthesia, Intravenous; Blood Pressure; Female; Half-Life; Heart Rate; Hemodynamics; H | 1992 |