propofol has been researched along with Syndrome in 112 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the effect of paravertebral administration of dexmedetomidine as an adjuvant to local anesthetic on the intraoperative anesthetic drug requirement and incidence of post-thoracotomy pain syndrome." | 9.24 | Effect of Continuous Paravertebral Dexmedetomidine Administration on Intraoperative Anesthetic Drug Requirement and Post-Thoracotomy Pain Syndrome After Thoracotomy: A Randomized Controlled Trial. ( Dutta, V; Jayant, A; Kumar, B; Mishra, AK, 2017) |
| "To investigate biochemically whether total intravenous anesthesia (TIVA) using propofol creates a risk for Propofol Infusion Syndrome (PRIS)." | 9.17 | Biochemical markers in total intravenous anesthesia and propofol infusion syndrome: a preliminary study. ( Gürses, E; Oztürk, I; Serin, S, 2013) |
| " Compared to earlier case reports in the literature, recently published cases describe older patients developing PRIS at lower doses of propofol, in whom arrhythmia, hypertriglyceridaemia and fever are less frequently seen, with survival more likely." | 8.91 | Propofol infusion syndrome: a structured review of experimental studies and 153 published case reports. ( Anděl, M; Duška, F; Krajčová, A; Waldauf, P, 2015) |
| " Keywords were propofol, propofol infusion syndrome (PRIS), rhabdomyolysis, heart failure, arrhythmias, metabolic acidosis, brain injury, sedation, intensive care." | 8.86 | [Propofol infusion syndrome]. ( Greff, B; Laquay, N; Meyer, P; Orliaguet, G; Prieur, S, 2010) |
| "Propofol infusion syndrome (PRIS) is defined as acute bradycardia progressing to asystole combined with lipemic plasma, fatty liver enlargement, metabolic acidosis with negative base excess >10 mmol l(-1), rhabdomyolysis or myoglobinuria associated with propofol infusion." | 8.85 | Propofol infusion syndrome: update of clinical manifestation and pathophysiology. ( Bein, B; Fudickar, A, 2009) |
| "A case of propofol infusion syndrome in a patient with respiratory failure and sepsis is reported." | 8.85 | Propofol infusion syndrome: case report and literature review. ( Chen, J; Cohen, N; Nadkarni, A; Orsini, J, 2009) |
| "The clinical features of propofol infusion syndrome (PRIS) are acute refractory bradycardia leading to asystole, in the presence of one or more of the following: metabolic acidosis (base deficit > 10 mmol." | 8.84 | Propofol infusion syndrome. ( Cardone, D; Kam, PC, 2007) |
| "The propofol infusion syndrome is a rare condition characterized by the occurrence of lactic acidosis, rhabdomyolysis and cardiovascular collapse following high-dose propofol infusion over prolonged periods of time." | 8.84 | Update on the propofol infusion syndrome in ICU management of patients with head injury. ( Cremer, OL; Kalkman, CJ; Otterspoor, LC, 2008) |
| "AstraZeneca (the manufacturer of Diprivan) presents its review of the history of the so-called 'propofol infusion syndrome', highlighting the difficulties in analysing the incomplete information available." | 8.83 | The 'propofol infusion syndrome': the facts, their interpretation and implications for patient care. ( Ahlen, K; Buckley, CJ; Goodale, DB; Pulsford, AH, 2006) |
| "Propofol infusion syndrome is a rare but often fatal syndrome, characterized by lactacidosis, lipaemic plasma and cardiac failure, associated with propofol infusion over prolonged periods of time." | 8.83 | Propofol infusion syndrome in anaesthesia and intensive care medicine. ( Bein, B; Fudickar, A; Tonner, PH, 2006) |
| "Propofol infusion syndrome (PRIS) is a rare and often fatal syndrome described in critically ill children undergoing long-term propofol infusion at high doses." | 8.82 | The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. ( Candiani, A; Latronico, N; Rasulo, F; Vasile, B, 2003) |
| "Propofol infusion syndrome has not only been observed in patients undergoing long-term sedation with propofol, but also during propofol anesthesia lasting 5 h." | 8.82 | [Propofol infusion syndrome]. ( Motsch, J; Roggenbach, J, 2004) |
| "Propofol infusion syndrome (PRIS), a rare complication of propofol sedation, is associated with high mortality." | 7.81 | Therapeutic plasma exchange as treatment for propofol infusion syndrome. ( Levin, PD; Levin, V; Rund, D; Sprung, CL; Weissman, C, 2015) |
| "Propofol infusion syndrome (PIS) is defined by arrhythmia, rhabdomyolysis, lactic acidosis, and unrecognized leads to death." | 7.80 | Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol. ( Clement, LP; Croce, MA; Fabian, TC; Fischer, PE; Lee, M; Magnotti, LJ; Schroeppel, TJ; Sharpe, JP, 2014) |
| "To address the issue of propofol-related infusion syndrome and its management." | 7.79 | Propofol-related infusion syndrome: role of propofol in medical complications of sedated critical care patients. ( Imam, TH, 2013) |
| "Propofol infusion syndrome (PRIS) is well known, often associated with, lethal complication of sedation with propofol." | 7.78 | Propofol infusion syndrome heralded by ECG changes. ( Aslan, A; Jacobs, B; Mijzen, EJ; Rodgers, MG, 2012) |
| "A case of PRIS is described in a 17-year-old female with refractory status epilepticus (RSE) who was receiving high-dose propofol for seizure control and sedation." | 7.77 | Propofol Infusion syndrome during refractory status epilepticus in a young adult: successful ECMO resuscitation. ( Al Habash, O; Boutoille, D; Bretonniere, C; Derkinderen, P; Gabillet, L; Guitton, C; Latour, P; Rigal, JC; Villers, D, 2011) |
| "Propofol infusion syndrome (PRIS) is a rare but frequently fatal condition." | 7.77 | Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage. ( Kumar, MA; Levine, JM; Pisapia, JM; Wendell, LC; Zager, EL, 2011) |
| "Here we describe a case of propofol-related infusion syndrome (PRIS) in a child with malignant refractory status epilepticus treated with partial-exchange blood transfusion (PEBT), an innovative method of resuscitation that has the potential to reduce the mortality rate associated with this syndrome." | 7.76 | Partial-exchange blood transfusion: an effective method for preventing mortality in a child with propofol infusion syndrome. ( Asuncion, A; Coquillon, P; Da-Silva, SS; Gavrilita, C; Wong, R, 2010) |
| "Propofol is a sedative, anesthetic, and antiepileptic agent that is frequently used in patients with refractory status epilepticus." | 7.75 | Propofol infusion syndrome in patients with refractory status epilepticus: an 11-year clinical experience. ( Hoel, R; Iyer, VN; Rabinstein, AA, 2009) |
| "The propofol infusion syndrome is a potentially devastating cardiovascular and metabolic derangement that has been described in both pediatric and adult patients sedated with propofol." | 7.75 | The propofol infusion syndrome: more puzzling evidence on a complex and poorly characterized disorder. ( Cremer, OL, 2009) |
| " Future controlled studies focusing on evaluating whether propofol manifests the derangements of critical illness more frequently than other sedatives will need to be large." | 7.75 | Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study. ( Anger, KE; Arpino, PA; Barletta, JF; Devlin, JW; Fong, JJ; Gerlach, AT; Grgurich, P; Kendall, E; Kuper, PJ; Papadopoulos, S; Roberts, RJ; Ruthazer, R; Schumaker, G; Szumita, PM; Voils, SA; Xamplas, R; Yogaratnam, D, 2009) |
| " After exclusion of potential causes for this phenomenon, it was attributed to perioperative intravenous propofol infusion causing propofol infusion syndrome." | 7.75 | Propofol infusion syndrome in adult cardiac surgery. ( Balacumaraswami, L; Ilyas, MI; Palin, C; Ratnatunga, C, 2009) |
| "To identify predictors of mortality in patients with suspected propofol infusion syndrome and to develop a simple scoring system to identify patients with suspected propofol infusion syndrome who are most at risk of death." | 7.74 | Predictors of mortality in patients with suspected propofol infusion syndrome. ( Devlin, JW; Fong, JJ; Kcomt, M; Ruthazer, R; Schumaker, G; Sylvia, L, 2008) |
| "Antimuscarinic syndrome (AS), a rare but serious adverse event associated with propofol should be included in the differential diagnosis of patients who develop agitation after its administration." | 7.74 | Antimuscarinic syndrome after propofol administration in the emergency department. ( Clements, EA; Eppert, AJ; Judge, BS; Snow, KA, 2007) |
| "Propofol is increasingly used for the treatment of status epilepticus due to the ease of use and tolerability, even if safety data from randomized clinical trials are lacking." | 7.74 | Propofol-associated fatal myocardial failure and rhabdomyolysis in an adult with status epilepticus. ( Harris, BT; Jobst, BC; Zarovnaya, EL, 2007) |
| "The authors report a case of short-term high-dose propofol-related metabolic acidosis in a 3-year-old girl." | 7.74 | Early propofol infusion syndrome following cerebral angiographic embolization for giant aneurysm repair. Case report. ( Muhonen, MG; Nwagwu, CI; Westhout, FD, 2007) |
| "The occurrence of metabolic acidosis, rhabdomyolysis, hyperkalemia, and sudden cardiac death after long-term, high-dose propofol infusion has been referred to as propofol infusion syndrome (PRIS)." | 7.73 | Electrocardiographic changes predicting sudden death in propofol-related infusion syndrome. ( Antzelevitch, C; Brugada, R; Cremer, OL; Crijns, HJ; Delhaas, T; Di Diego, JM; Kalkman, CJ; Oliva, A; Prinzen, FW; Rodriguez, LM; Timmermans, C; Vernooy, K; Volders, PG, 2006) |
| "Propofol infusion syndrome is described in the pediatric literature as metabolic acidosis, rhabdomyolysis, and bradycardia that results in death." | 7.73 | The syndrome of irreversible acidosis after prolonged propofol infusion. ( Abou-Khaled, KJ; Kumar, MA; Schwartzman, RJ; Thomas, CE; Urrutia, VC, 2005) |
| "The propofol infusion syndrome is a rare but potentially lethal complication resulting from a prolonged continuous administration of propofol." | 7.73 | [Propofol infusion syndrome]. ( Jost, R; Likar, R; Oher, M; Pointner, I; Schalk, HV; Trampitsch, E, 2006) |
| "Propofol infusion syndrome has been increasingly recognized as a syndrome of unexplained myocardial failure, metabolic acidosis, and rhabdomyolysis with renal failure." | 7.72 | Propofol infusion syndrome: an unusual cause of renal failure. ( Casserly, B; Eisele, G; Haqqie, S; O'Mahony, E; Timm, EG; Urizar, R, 2004) |
| "Propofol is used for the treatment of refractory status epilepticus." | 7.72 | Fatal propofol infusion syndrome in association with ketogenic diet. ( Baumeister, FA; Eberhardt, J; Holthausen, H; Kunkel, J; Liebhaber, GM; Oberhoffer, R; Peters, J, 2004) |
| "This report describes a fatal case of the propofol infusion syndrome in an adult patient being sedated for a closed head injury using high doses of propofol." | 7.72 | Propofol infusion syndrome--report of an adult fatality. ( Ernest, D; French, C, 2003) |
| "Propofol infusion syndrome is a rare but frequently fatal complication in critically ill children given long-term propofol infusions." | 7.71 | Impaired fatty acid oxidation in propofol infusion syndrome. ( Segar, P; Shield, J; Stone, J; Weir, P; Wolf, A, 2001) |
| "The author presents a case report where, following propofol sedation for a peribulbar block, sneezing was induced once the local anaesthetic needle was placed in the orbital cavity." | 7.69 | Sudden unexpected sneezing during the insertion of peribulbar block under propofol sedation. ( Abramson, DC, 1995) |
| "Propofol is a short-acting intravenous anesthetic agent widely used for sedation in anesthesia and intensive care." | 6.44 | The propofol infusion 'syndrome' in intensive care unit: from pathophysiology to prophylaxis and treatment. ( Dragoumanis, C; Papaioannou, V; Pneumatikos, I; Theodorou, V, 2008) |
| "Propofol has gained popularity for its rapid onset and rapid recovery even after prolonged use, and for the neuroprotection conferred." | 6.44 | Propofol infusion syndrome: an overview of a perplexing disease. ( Fodale, V; La Monaca, E, 2008) |
| "During this period 44 children with respiratory tract infections had been admitted to this unit and sedated for at least 48 h." | 6.40 | Propofol infusion syndrome in children. ( Bray, RJ, 1998) |
| "Propofol was utilized as part of the anesthetic protocol." | 5.48 | Propofol infusion-like syndrome in a dog. ( Mallard, JM; Peterson, NW; Rieser, TM, 2018) |
| "Propofol is a short-acting intravenous anesthetic agent." | 5.42 | Possible pathogenic mechanism of propofol infusion syndrome involves coenzyme q. ( Dacremont, G; de Jaeger, A; De Latter, E; De Paepe, B; De Paepe, P; Jorens, PG; Okun, JG; Smet, J; Van Coster, R; Van Regenmortel, N; Vanheel, B; Vanlander, AV; Wuyts, B, 2015) |
| "Propofol is an anesthetic agent widely used for induction and maintenance of anesthesia, and sedation in children." | 5.38 | Inborn oxidative phosphorylation defect as risk factor for propofol infusion syndrome. ( De Paepe, B; Jorens, PG; Lissens, W; Meire, F; Okun, JG; Pauwels, P; Seneca, S; Smet, J; Van Coster, R; Van den Eynden, GG; Van der Aa, N; Vanlander, AV; Verbrugghe, W, 2012) |
| "Propofol infusion syndrome is a rare but frequently fatal complication in critically ill children who are given prolonged high-dose infusions of the drug." | 5.34 | Propofol infusion syndrome: a case of increasing morbidity with traumatic brain injury. ( Coritsidis, G; Rehman, Z; Sabsovich, I; Yunen, J, 2007) |
| "She developed multiple organ failure with rhabdomyolysis and died." | 5.33 | A case of suspected non-neurosurgical adult fatal propofol infusion syndrome. ( Eriksen, J; Povey, HM, 2006) |
| "Propofol was administered at the dose of 3-5 mg." | 5.31 | [A case of hyperperfusion syndrome treated successfully by propofol]. ( Horinouchi, T; Kato, M; Sato, K; Shimizu, H, 2001) |
| "To assess the effect of paravertebral administration of dexmedetomidine as an adjuvant to local anesthetic on the intraoperative anesthetic drug requirement and incidence of post-thoracotomy pain syndrome." | 5.24 | Effect of Continuous Paravertebral Dexmedetomidine Administration on Intraoperative Anesthetic Drug Requirement and Post-Thoracotomy Pain Syndrome After Thoracotomy: A Randomized Controlled Trial. ( Dutta, V; Jayant, A; Kumar, B; Mishra, AK, 2017) |
| "To investigate biochemically whether total intravenous anesthesia (TIVA) using propofol creates a risk for Propofol Infusion Syndrome (PRIS)." | 5.17 | Biochemical markers in total intravenous anesthesia and propofol infusion syndrome: a preliminary study. ( Gürses, E; Oztürk, I; Serin, S, 2013) |
| " Compared to earlier case reports in the literature, recently published cases describe older patients developing PRIS at lower doses of propofol, in whom arrhythmia, hypertriglyceridaemia and fever are less frequently seen, with survival more likely." | 4.91 | Propofol infusion syndrome: a structured review of experimental studies and 153 published case reports. ( Anděl, M; Duška, F; Krajčová, A; Waldauf, P, 2015) |
| " Keywords were propofol, propofol infusion syndrome (PRIS), rhabdomyolysis, heart failure, arrhythmias, metabolic acidosis, brain injury, sedation, intensive care." | 4.86 | [Propofol infusion syndrome]. ( Greff, B; Laquay, N; Meyer, P; Orliaguet, G; Prieur, S, 2010) |
| "A case of propofol infusion syndrome in a patient with respiratory failure and sepsis is reported." | 4.85 | Propofol infusion syndrome: case report and literature review. ( Chen, J; Cohen, N; Nadkarni, A; Orsini, J, 2009) |
| "Propofol infusion syndrome (PRIS) is defined as acute bradycardia progressing to asystole combined with lipemic plasma, fatty liver enlargement, metabolic acidosis with negative base excess >10 mmol l(-1), rhabdomyolysis or myoglobinuria associated with propofol infusion." | 4.85 | Propofol infusion syndrome: update of clinical manifestation and pathophysiology. ( Bein, B; Fudickar, A, 2009) |
| "The propofol infusion syndrome is a rare condition characterized by the occurrence of lactic acidosis, rhabdomyolysis and cardiovascular collapse following high-dose propofol infusion over prolonged periods of time." | 4.84 | Update on the propofol infusion syndrome in ICU management of patients with head injury. ( Cremer, OL; Kalkman, CJ; Otterspoor, LC, 2008) |
| "The clinical features of propofol infusion syndrome (PRIS) are acute refractory bradycardia leading to asystole, in the presence of one or more of the following: metabolic acidosis (base deficit > 10 mmol." | 4.84 | Propofol infusion syndrome. ( Cardone, D; Kam, PC, 2007) |
| "Propofol infusion syndrome is a rare but often fatal syndrome, characterized by lactacidosis, lipaemic plasma and cardiac failure, associated with propofol infusion over prolonged periods of time." | 4.83 | Propofol infusion syndrome in anaesthesia and intensive care medicine. ( Bein, B; Fudickar, A; Tonner, PH, 2006) |
| "AstraZeneca (the manufacturer of Diprivan) presents its review of the history of the so-called 'propofol infusion syndrome', highlighting the difficulties in analysing the incomplete information available." | 4.83 | The 'propofol infusion syndrome': the facts, their interpretation and implications for patient care. ( Ahlen, K; Buckley, CJ; Goodale, DB; Pulsford, AH, 2006) |
| "Propofol infusion syndrome (PRIS) is a rare and often fatal syndrome described in critically ill children undergoing long-term propofol infusion at high doses." | 4.82 | The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. ( Candiani, A; Latronico, N; Rasulo, F; Vasile, B, 2003) |
| "Propofol infusion syndrome has not only been observed in patients undergoing long-term sedation with propofol, but also during propofol anesthesia lasting 5 h." | 4.82 | [Propofol infusion syndrome]. ( Motsch, J; Roggenbach, J, 2004) |
| " In the first operation, in which anesthesia induction was applied with ketamine and midazolam, extremity movements with surgical stimuli were seen." | 3.85 | Anesthesia Procedure for Congenital Insensitivity to Pain in a Child with Anhidrosis Syndrome: A Rare Case. ( Arslan, M; Balaban, A; Duman, Y; Gisi, G; Oksuz, G; Oksuz, H; Urfalioglu, A; Yildiz, H, 2017) |
| "Propofol infusion syndrome (PRIS), a rare complication of propofol sedation, is associated with high mortality." | 3.81 | Therapeutic plasma exchange as treatment for propofol infusion syndrome. ( Levin, PD; Levin, V; Rund, D; Sprung, CL; Weissman, C, 2015) |
| "Propofol infusion syndrome (PIS) is defined by arrhythmia, rhabdomyolysis, lactic acidosis, and unrecognized leads to death." | 3.80 | Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol. ( Clement, LP; Croce, MA; Fabian, TC; Fischer, PE; Lee, M; Magnotti, LJ; Schroeppel, TJ; Sharpe, JP, 2014) |
| "To address the issue of propofol-related infusion syndrome and its management." | 3.79 | Propofol-related infusion syndrome: role of propofol in medical complications of sedated critical care patients. ( Imam, TH, 2013) |
| "Propofol infusion syndrome (PRIS) is well known, often associated with, lethal complication of sedation with propofol." | 3.78 | Propofol infusion syndrome heralded by ECG changes. ( Aslan, A; Jacobs, B; Mijzen, EJ; Rodgers, MG, 2012) |
| "A case of PRIS is described in a 17-year-old female with refractory status epilepticus (RSE) who was receiving high-dose propofol for seizure control and sedation." | 3.77 | Propofol Infusion syndrome during refractory status epilepticus in a young adult: successful ECMO resuscitation. ( Al Habash, O; Boutoille, D; Bretonniere, C; Derkinderen, P; Gabillet, L; Guitton, C; Latour, P; Rigal, JC; Villers, D, 2011) |
| "Propofol infusion syndrome (PRIS) is a rare but frequently fatal condition." | 3.77 | Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage. ( Kumar, MA; Levine, JM; Pisapia, JM; Wendell, LC; Zager, EL, 2011) |
| "Here we describe a case of propofol-related infusion syndrome (PRIS) in a child with malignant refractory status epilepticus treated with partial-exchange blood transfusion (PEBT), an innovative method of resuscitation that has the potential to reduce the mortality rate associated with this syndrome." | 3.76 | Partial-exchange blood transfusion: an effective method for preventing mortality in a child with propofol infusion syndrome. ( Asuncion, A; Coquillon, P; Da-Silva, SS; Gavrilita, C; Wong, R, 2010) |
| " We report a case of safe perioperative management with general anesthesia, using total intravenous anesthesia, propofol, fentanyl and a non-depolarizing muscle relaxant but avoiding the use of any inhaled anesthetics or depolarizing muscle relaxants to prevent malignant hyperthermia and postoperative respiratory failure, during anesthetic management for cranioplasty for premature synostosis of the cranial sutures in a pediatric patient of CNMDU1." | 3.76 | Anesthetic case in a child with congenital neuromuscular disease with uniform type 1 fibers (CNMDU1). ( Arashi, D; Okutani, R; Tsujii, K, 2010) |
| "The propofol infusion syndrome is a potentially devastating cardiovascular and metabolic derangement that has been described in both pediatric and adult patients sedated with propofol." | 3.75 | The propofol infusion syndrome: more puzzling evidence on a complex and poorly characterized disorder. ( Cremer, OL, 2009) |
| " Future controlled studies focusing on evaluating whether propofol manifests the derangements of critical illness more frequently than other sedatives will need to be large." | 3.75 | Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study. ( Anger, KE; Arpino, PA; Barletta, JF; Devlin, JW; Fong, JJ; Gerlach, AT; Grgurich, P; Kendall, E; Kuper, PJ; Papadopoulos, S; Roberts, RJ; Ruthazer, R; Schumaker, G; Szumita, PM; Voils, SA; Xamplas, R; Yogaratnam, D, 2009) |
| "Propofol is a sedative, anesthetic, and antiepileptic agent that is frequently used in patients with refractory status epilepticus." | 3.75 | Propofol infusion syndrome in patients with refractory status epilepticus: an 11-year clinical experience. ( Hoel, R; Iyer, VN; Rabinstein, AA, 2009) |
| " After exclusion of potential causes for this phenomenon, it was attributed to perioperative intravenous propofol infusion causing propofol infusion syndrome." | 3.75 | Propofol infusion syndrome in adult cardiac surgery. ( Balacumaraswami, L; Ilyas, MI; Palin, C; Ratnatunga, C, 2009) |
| "To identify predictors of mortality in patients with suspected propofol infusion syndrome and to develop a simple scoring system to identify patients with suspected propofol infusion syndrome who are most at risk of death." | 3.74 | Predictors of mortality in patients with suspected propofol infusion syndrome. ( Devlin, JW; Fong, JJ; Kcomt, M; Ruthazer, R; Schumaker, G; Sylvia, L, 2008) |
| "Propofol is increasingly used for the treatment of status epilepticus due to the ease of use and tolerability, even if safety data from randomized clinical trials are lacking." | 3.74 | Propofol-associated fatal myocardial failure and rhabdomyolysis in an adult with status epilepticus. ( Harris, BT; Jobst, BC; Zarovnaya, EL, 2007) |
| "The authors report a case of short-term high-dose propofol-related metabolic acidosis in a 3-year-old girl." | 3.74 | Early propofol infusion syndrome following cerebral angiographic embolization for giant aneurysm repair. Case report. ( Muhonen, MG; Nwagwu, CI; Westhout, FD, 2007) |
| "Antimuscarinic syndrome (AS), a rare but serious adverse event associated with propofol should be included in the differential diagnosis of patients who develop agitation after its administration." | 3.74 | Antimuscarinic syndrome after propofol administration in the emergency department. ( Clements, EA; Eppert, AJ; Judge, BS; Snow, KA, 2007) |
| "Propofol infusion syndrome is described in the pediatric literature as metabolic acidosis, rhabdomyolysis, and bradycardia that results in death." | 3.73 | The syndrome of irreversible acidosis after prolonged propofol infusion. ( Abou-Khaled, KJ; Kumar, MA; Schwartzman, RJ; Thomas, CE; Urrutia, VC, 2005) |
| "The occurrence of metabolic acidosis, rhabdomyolysis, hyperkalemia, and sudden cardiac death after long-term, high-dose propofol infusion has been referred to as propofol infusion syndrome (PRIS)." | 3.73 | Electrocardiographic changes predicting sudden death in propofol-related infusion syndrome. ( Antzelevitch, C; Brugada, R; Cremer, OL; Crijns, HJ; Delhaas, T; Di Diego, JM; Kalkman, CJ; Oliva, A; Prinzen, FW; Rodriguez, LM; Timmermans, C; Vernooy, K; Volders, PG, 2006) |
| "The propofol infusion syndrome is a rare but potentially lethal complication resulting from a prolonged continuous administration of propofol." | 3.73 | [Propofol infusion syndrome]. ( Jost, R; Likar, R; Oher, M; Pointner, I; Schalk, HV; Trampitsch, E, 2006) |
| "Propofol infusion syndrome has been increasingly recognized as a syndrome of unexplained myocardial failure, metabolic acidosis, and rhabdomyolysis with renal failure." | 3.72 | Propofol infusion syndrome: an unusual cause of renal failure. ( Casserly, B; Eisele, G; Haqqie, S; O'Mahony, E; Timm, EG; Urizar, R, 2004) |
| "Propofol is used for the treatment of refractory status epilepticus." | 3.72 | Fatal propofol infusion syndrome in association with ketogenic diet. ( Baumeister, FA; Eberhardt, J; Holthausen, H; Kunkel, J; Liebhaber, GM; Oberhoffer, R; Peters, J, 2004) |
| "We review the anesthetic implications of Joubert syndrome and report that spinal anesthesia under intravenous propofol sedation proved satisfactory for repair of an inguinal hernia in a spontaneously ventilating infant with this syndrome." | 3.72 | Anesthetic management in Joubert syndrome. ( Gordon, GJ; Vodopich, DJ, 2004) |
| "This case report discusses the cause of death in a 3-year-old child who survived a high dose (20 mg x kg-1 x h-1) of propofol, infused over a period of 15 h, following which the patient developed a combined respiratory and metabolic acidosis, the oxygenation remaining normal." | 3.72 | Death after re-exposure to propofol in a 3-year-old child: a case report. ( Aring, C; Gillor, A; Holzki, J, 2004) |
| "This report describes a fatal case of the propofol infusion syndrome in an adult patient being sedated for a closed head injury using high doses of propofol." | 3.72 | Propofol infusion syndrome--report of an adult fatality. ( Ernest, D; French, C, 2003) |
| "Propofol infusion syndrome is a rare but frequently fatal complication in critically ill children given long-term propofol infusions." | 3.71 | Impaired fatty acid oxidation in propofol infusion syndrome. ( Segar, P; Shield, J; Stone, J; Weir, P; Wolf, A, 2001) |
| "The author presents a case report where, following propofol sedation for a peribulbar block, sneezing was induced once the local anaesthetic needle was placed in the orbital cavity." | 3.69 | Sudden unexpected sneezing during the insertion of peribulbar block under propofol sedation. ( Abramson, DC, 1995) |
| "Propofol is a potent intravenous anesthetic agent that rapidly induces sedation and unconsciousness." | 2.47 | Clinical effects and lethal and forensic aspects of propofol. ( Levy, RJ, 2011) |
| "Propofol has gained popularity for its rapid onset and rapid recovery even after prolonged use, and for the neuroprotection conferred." | 2.44 | Propofol infusion syndrome: an overview of a perplexing disease. ( Fodale, V; La Monaca, E, 2008) |
| "Propofol is a short-acting intravenous anesthetic agent widely used for sedation in anesthesia and intensive care." | 2.44 | The propofol infusion 'syndrome' in intensive care unit: from pathophysiology to prophylaxis and treatment. ( Dragoumanis, C; Papaioannou, V; Pneumatikos, I; Theodorou, V, 2008) |
| "During this period 44 children with respiratory tract infections had been admitted to this unit and sedated for at least 48 h." | 2.40 | Propofol infusion syndrome in children. ( Bray, RJ, 1998) |
| "Propofol was utilized as part of the anesthetic protocol." | 1.48 | Propofol infusion-like syndrome in a dog. ( Mallard, JM; Peterson, NW; Rieser, TM, 2018) |
| "Propofol is a short-acting intravenous anesthetic agent." | 1.42 | Possible pathogenic mechanism of propofol infusion syndrome involves coenzyme q. ( Dacremont, G; de Jaeger, A; De Latter, E; De Paepe, B; De Paepe, P; Jorens, PG; Okun, JG; Smet, J; Van Coster, R; Van Regenmortel, N; Vanheel, B; Vanlander, AV; Wuyts, B, 2015) |
| "Propofol is an anesthetic agent widely used for induction and maintenance of anesthesia, and sedation in children." | 1.38 | Inborn oxidative phosphorylation defect as risk factor for propofol infusion syndrome. ( De Paepe, B; Jorens, PG; Lissens, W; Meire, F; Okun, JG; Pauwels, P; Seneca, S; Smet, J; Van Coster, R; Van den Eynden, GG; Van der Aa, N; Vanlander, AV; Verbrugghe, W, 2012) |
| "Freeman-Sheldon syndrome, or distal arthrogryposis type 2A, is a rare congenital myopathy and dysplasia characterised by multiple contractures, abnormalities of the head and face, defective development of the hands and feet and skeletal malformations." | 1.35 | Anaesthetic management of a child with Freeman-sheldon syndrome undergoing spinal surgery. ( Richa, FC; Yazbeck, PH, 2008) |
| "Propofol infusion syndrome is a rare but frequently fatal complication in critically ill children who are given prolonged high-dose infusions of the drug." | 1.34 | Propofol infusion syndrome: a case of increasing morbidity with traumatic brain injury. ( Coritsidis, G; Rehman, Z; Sabsovich, I; Yunen, J, 2007) |
| "She developed multiple organ failure with rhabdomyolysis and died." | 1.33 | A case of suspected non-neurosurgical adult fatal propofol infusion syndrome. ( Eriksen, J; Povey, HM, 2006) |
| "This syndrome is relatively uncommon and accompanies dyspnea and hypoxemia on changing to a sitting or standing from recumbent position." | 1.32 | [Anesthetic management for a patient with platypnea-orthodeoxia syndrome]. ( Kawamoto, K; Terasaki, H; Yoshitake, A, 2004) |
| "Propofol was stopped." | 1.32 | A case of propofol toxicity: further evidence for a causal mechanism. ( Al Ayed, T; Decell, MK; Withington, DE, 2004) |
| "Sotos syndrome is a rare condition characterized by typical facies, early accelerated growth, large body size, developmental delay and congenital heart defects." | 1.32 | Anaesthesia in a child with Sotos syndrome. ( Adhami, EJ; Cancio-Babu, CV, 2003) |
| "Propofol was administered at the dose of 3-5 mg." | 1.31 | [A case of hyperperfusion syndrome treated successfully by propofol]. ( Horinouchi, T; Kato, M; Sato, K; Shimizu, H, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (7.14) | 18.2507 |
| 2000's | 73 (65.18) | 29.6817 |
| 2010's | 31 (27.68) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Urfalioglu, A | 1 |
| Arslan, M | 1 |
| Duman, Y | 1 |
| Gisi, G | 1 |
| Oksuz, G | 1 |
| Yildiz, H | 1 |
| Oksuz, H | 1 |
| Balaban, A | 1 |
| Choi, SR | 1 |
| Kim, JH | 1 |
| Chae, KL | 1 |
| Lee, SC | 1 |
| Park, SY | 1 |
| Mallard, JM | 1 |
| Rieser, TM | 1 |
| Peterson, NW | 1 |
| Imam, TH | 1 |
| Schroeppel, TJ | 1 |
| Fabian, TC | 1 |
| Clement, LP | 1 |
| Fischer, PE | 1 |
| Magnotti, LJ | 1 |
| Sharpe, JP | 1 |
| Lee, M | 1 |
| Croce, MA | 1 |
| Savard, M | 1 |
| Dupré, N | 1 |
| Turgeon, AF | 1 |
| Desbiens, R | 1 |
| Langevin, S | 1 |
| Brunet, D | 1 |
| Oztürk, I | 1 |
| Serin, S | 1 |
| Gürses, E | 1 |
| Poretti, A | 1 |
| Bosemani, T | 1 |
| Huisman, TA | 1 |
| Vanlander, AV | 2 |
| Okun, JG | 2 |
| de Jaeger, A | 1 |
| Smet, J | 2 |
| De Latter, E | 1 |
| De Paepe, B | 2 |
| Dacremont, G | 1 |
| Wuyts, B | 1 |
| Vanheel, B | 1 |
| De Paepe, P | 1 |
| Jorens, PG | 2 |
| Van Regenmortel, N | 1 |
| Van Coster, R | 2 |
| Chen, L | 1 |
| Lim, FA | 1 |
| Levin, PD | 1 |
| Levin, V | 1 |
| Weissman, C | 1 |
| Sprung, CL | 1 |
| Rund, D | 1 |
| Krajčová, A | 1 |
| Waldauf, P | 1 |
| Anděl, M | 1 |
| Duška, F | 1 |
| Honore, PM | 1 |
| Spapen, HD | 1 |
| Dutta, V | 1 |
| Kumar, B | 1 |
| Jayant, A | 1 |
| Mishra, AK | 1 |
| Zaccheo, MM | 1 |
| Bucher, DH | 1 |
| Papaioannou, V | 1 |
| Dragoumanis, C | 1 |
| Theodorou, V | 1 |
| Pneumatikos, I | 1 |
| Fong, JJ | 2 |
| Sylvia, L | 1 |
| Ruthazer, R | 2 |
| Schumaker, G | 2 |
| Kcomt, M | 1 |
| Devlin, JW | 3 |
| Otterspoor, LC | 1 |
| Kalkman, CJ | 2 |
| Cremer, OL | 3 |
| Bader, MK | 1 |
| Vislosky, M | 1 |
| Bebarta, VS | 2 |
| Summers, S | 2 |
| Pavlov, OO | 1 |
| Laquay, N | 2 |
| Pouard, P | 1 |
| Silicani, MA | 1 |
| Vaccaroni, L | 1 |
| Orliaguet, G | 2 |
| Ilyas, MI | 1 |
| Balacumaraswami, L | 1 |
| Palin, C | 1 |
| Ratnatunga, C | 1 |
| Blossom, DB | 1 |
| Chen, TH | 1 |
| Li, J | 1 |
| Langer, AJ | 1 |
| Carpenter, LR | 1 |
| Glenshaw, MT | 1 |
| Gould, CV | 1 |
| Weltman, A | 1 |
| Srinivasan, A | 1 |
| Fudickar, A | 3 |
| Bein, B | 3 |
| Orsini, J | 1 |
| Nadkarni, A | 1 |
| Chen, J | 2 |
| Cohen, N | 1 |
| Iyer, VN | 1 |
| Hoel, R | 1 |
| Rabinstein, AA | 1 |
| Blum, JM | 1 |
| Brunsvold, ME | 1 |
| Roberts, RJ | 1 |
| Barletta, JF | 1 |
| Kuper, PJ | 1 |
| Papadopoulos, S | 1 |
| Yogaratnam, D | 1 |
| Kendall, E | 1 |
| Xamplas, R | 1 |
| Gerlach, AT | 1 |
| Szumita, PM | 1 |
| Anger, KE | 1 |
| Arpino, PA | 1 |
| Voils, SA | 1 |
| Grgurich, P | 1 |
| Riker, RR | 2 |
| Glisic, EK | 1 |
| Fraser, GL | 1 |
| Shoemaker, JD | 1 |
| Prieur, S | 1 |
| Greff, B | 1 |
| Meyer, P | 1 |
| Schneemilch, C | 1 |
| Da-Silva, SS | 1 |
| Wong, R | 1 |
| Coquillon, P | 1 |
| Gavrilita, C | 1 |
| Asuncion, A | 1 |
| Guitton, C | 1 |
| Gabillet, L | 1 |
| Latour, P | 1 |
| Rigal, JC | 1 |
| Boutoille, D | 1 |
| Al Habash, O | 1 |
| Derkinderen, P | 1 |
| Bretonniere, C | 1 |
| Villers, D | 1 |
| Mallow-Corbett, S | 1 |
| Okutani, R | 1 |
| Arashi, D | 1 |
| Tsujii, K | 1 |
| Levy, RJ | 1 |
| Fernández, AB | 1 |
| Fernández, J | 1 |
| Pisapia, JM | 1 |
| Wendell, LC | 1 |
| Kumar, MA | 2 |
| Zager, EL | 1 |
| Levine, JM | 1 |
| Amrein, S | 1 |
| Amrein, K | 1 |
| Amegah-Sakotnik, A | 1 |
| Reist, U | 1 |
| Ensner, R | 1 |
| Faulkner, MJ | 1 |
| Haley, MW | 1 |
| Littmann, L | 1 |
| Pickard, A | 1 |
| Verbrugghe, W | 1 |
| Van den Eynden, GG | 1 |
| Meire, F | 1 |
| Pauwels, P | 1 |
| Van der Aa, N | 1 |
| Seneca, S | 1 |
| Lissens, W | 1 |
| Testerman, GM | 1 |
| Chow, TT | 1 |
| Easparam, S | 1 |
| Annecke, T | 1 |
| Conzen, P | 1 |
| Ney, L | 1 |
| Mijzen, EJ | 1 |
| Jacobs, B | 1 |
| Aslan, A | 1 |
| Rodgers, MG | 1 |
| Crawford, MW | 1 |
| Dodgson, BG | 1 |
| Holtby, HH | 1 |
| Roy, WL | 1 |
| Sloan, IA | 1 |
| Pulsford, AH | 2 |
| Ernest, D | 1 |
| French, C | 1 |
| Vasile, B | 1 |
| Rasulo, F | 1 |
| Candiani, A | 1 |
| Latronico, N | 1 |
| Lirk, P | 1 |
| Rieder, J | 1 |
| Schuerholz, A | 1 |
| Keller, C | 1 |
| Adhami, EJ | 1 |
| Cancio-Babu, CV | 1 |
| Koch, M | 1 |
| De Backer, D | 1 |
| Vincent, JL | 1 |
| Holzki, J | 1 |
| Aring, C | 1 |
| Gillor, A | 1 |
| Kawamoto, K | 1 |
| Yoshitake, A | 1 |
| Terasaki, H | 1 |
| Wolf, AR | 1 |
| Potter, F | 1 |
| Withington, DE | 1 |
| Decell, MK | 1 |
| Al Ayed, T | 1 |
| Baumeister, FA | 1 |
| Oberhoffer, R | 1 |
| Liebhaber, GM | 1 |
| Kunkel, J | 1 |
| Eberhardt, J | 1 |
| Holthausen, H | 1 |
| Peters, J | 1 |
| Vodopich, DJ | 1 |
| Gordon, GJ | 1 |
| Motsch, J | 1 |
| Roggenbach, J | 1 |
| Casserly, B | 1 |
| O'Mahony, E | 1 |
| Timm, EG | 1 |
| Haqqie, S | 1 |
| Eisele, G | 1 |
| Urizar, R | 1 |
| Machata, AM | 1 |
| Gonano, C | 1 |
| Bîrsan, T | 1 |
| Zimpfer, M | 1 |
| Spiss, CK | 1 |
| Uezono, S | 1 |
| Hotta, Y | 1 |
| Takakuwa, Y | 1 |
| Ozaki, M | 1 |
| Colomb, S | 1 |
| Gonzalez, D | 1 |
| Dissait, F | 1 |
| Urrutia, VC | 1 |
| Thomas, CE | 1 |
| Abou-Khaled, KJ | 1 |
| Schwartzman, RJ | 1 |
| Wessel, N | 1 |
| Schirdewan, A | 1 |
| Vernooy, K | 1 |
| Delhaas, T | 1 |
| Di Diego, JM | 1 |
| Oliva, A | 1 |
| Timmermans, C | 1 |
| Volders, PG | 1 |
| Prinzen, FW | 1 |
| Crijns, HJ | 1 |
| Antzelevitch, C | 1 |
| Rodriguez, LM | 1 |
| Brugada, R | 1 |
| Eriksen, J | 1 |
| Povey, HM | 1 |
| Salengros, JC | 1 |
| Engelman, E | 1 |
| Hermanns, H | 1 |
| Lipfert, P | 1 |
| Ladda, S | 1 |
| Stevens, MF | 1 |
| Tonner, PH | 2 |
| Cohen, S | 1 |
| Hunter, CW | 1 |
| Yanni, B | 1 |
| Striker, P | 1 |
| Hijazi, RH | 1 |
| Ahlen, K | 1 |
| Buckley, CJ | 1 |
| Goodale, DB | 1 |
| Trampitsch, E | 1 |
| Oher, M | 1 |
| Pointner, I | 1 |
| Likar, R | 1 |
| Jost, R | 1 |
| Schalk, HV | 1 |
| Platis, CM | 1 |
| Wasersprung, D | 1 |
| Kachko, L | 1 |
| Tsunzer, I | 1 |
| Katz, J | 1 |
| De Waele, JJ | 1 |
| Hoste, E | 1 |
| Wysowski, DK | 1 |
| Pollock, ML | 1 |
| Crozier, TA | 1 |
| Sabsovich, I | 1 |
| Rehman, Z | 1 |
| Yunen, J | 1 |
| Coritsidis, G | 1 |
| Guibert Bayona, MA | 1 |
| Borque Martín, JL | 1 |
| Araújo Fernández, AM | 1 |
| Ruiz Ilundáin, G | 1 |
| Westhout, FD | 1 |
| Muhonen, MG | 1 |
| Nwagwu, CI | 1 |
| Zarovnaya, EL | 1 |
| Jobst, BC | 1 |
| Harris, BT | 1 |
| Karakitsos, D | 1 |
| Poularas, J | 1 |
| Kalogeromitros, A | 1 |
| Karabinis, A | 1 |
| Lynch, G | 1 |
| Clinton, S | 1 |
| Siotia, A | 1 |
| Kam, PC | 1 |
| Cardone, D | 1 |
| Snow, KA | 1 |
| Clements, EA | 1 |
| Eppert, AJ | 1 |
| Judge, BS | 1 |
| Rosen, DJ | 1 |
| Nicoara, A | 1 |
| Koshy, N | 1 |
| Wedderburn, RV | 1 |
| Rozet, I | 1 |
| Lam, AM | 1 |
| Corbett, SM | 1 |
| Montoya, ID | 1 |
| Moore, FA | 1 |
| Hill, M | 1 |
| Peat, W | 1 |
| Courtman, S | 1 |
| Knab, J | 1 |
| Heupel, EW | 1 |
| Steinmann, D | 1 |
| Richa, FC | 1 |
| Yazbeck, PH | 1 |
| Fodale, V | 1 |
| La Monaca, E | 1 |
| Bhakta, P | 1 |
| Goel, A | 1 |
| Acharjee, P | 1 |
| Biswas, BK | 1 |
| Mihaljovic, Z | 1 |
| Dellien, C | 1 |
| Weiler, N | 1 |
| Scholz, J | 1 |
| Abramson, DC | 1 |
| Borges, M | 1 |
| Antognini, JF | 1 |
| Bray, RJ | 2 |
| Susla, GM | 1 |
| Hatch, DJ | 1 |
| Jorgensen, BG | 1 |
| Laub, M | 1 |
| Knudsen, RH | 1 |
| Hashiguchi, K | 1 |
| O'Higashi, T | 1 |
| Sasai, S | 1 |
| Kiguchi, T | 1 |
| Uga, H | 1 |
| Matsuura, H | 1 |
| Sato, K | 1 |
| Shimizu, H | 1 |
| Horinouchi, T | 1 |
| Kato, M | 1 |
| Wolf, A | 1 |
| Weir, P | 1 |
| Segar, P | 1 |
| Stone, J | 1 |
| Shield, J | 1 |
| Myburgh, JA | 1 |
| Upton, RN | 1 |
| Abrahams, JM | 1 |
| Reiter, GT | 1 |
| Acker, MA | 1 |
| Sinson, GP | 1 |
| Friedman, JA | 1 |
| Manno, E | 1 |
| Fulgham, JR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia[NCT04235894] | 124 participants (Actual) | Observational | 2016-09-07 | Completed | |||
| Keto-diet for Intubated Critical Care COVID-19 (KICC-COVID19)[NCT04358835] | 0 participants (Actual) | Interventional | 2020-09-01 | Withdrawn (stopped due to Study did not begin enrollment, multiple competing studies at same institution) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
21 reviews available for propofol and Syndrome
| Article | Year |
|---|---|
Propofol infusion syndrome: a structured review of experimental studies and 153 published case reports.
Topics: Anesthetics, Intravenous; Arrhythmias, Cardiac; Fever; Heart Failure; Hepatomegaly; Humans; Hypertri | 2015 |
Propofol infusion syndrome: a rare complication with potentially fatal results.
Topics: Acidosis; Acute Kidney Injury; Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Critical Care; | 2008 |
The propofol infusion 'syndrome' in intensive care unit: from pathophysiology to prophylaxis and treatment.
Topics: Acidosis; Adult; Anesthetics, Intravenous; Cardiovascular Diseases; Child; Heart; Humans; Hyperkalem | 2008 |
Update on the propofol infusion syndrome in ICU management of patients with head injury.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Brain Injuries; Critical Care; Dose-Response Rela | 2008 |
Propofol infusion syndrome: update of clinical manifestation and pathophysiology.
Topics: Acidosis; Acute Disease; Adult; Age Factors; Anesthetics, Intravenous; Animals; Bradycardia; Brain I | 2009 |
Propofol infusion syndrome: case report and literature review.
Topics: Adult; Anesthetics, Intravenous; Drug Administration Schedule; Exanthema; Female; Hepatomegaly; Huma | 2009 |
[Propofol infusion syndrome].
Topics: Acidosis; Arrhythmias, Cardiac; Heart Failure; Humans; Hypnotics and Sedatives; Infusions, Intraveno | 2010 |
Adverse drug events associated with the use of analgesics, sedatives, and antipsychotics in the intensive care unit.
Topics: Acidosis; Analgesics; Antipsychotic Agents; Bradycardia; Cardiovascular Diseases; Critical Care; Dru | 2010 |
Clinical effects and lethal and forensic aspects of propofol.
Topics: Accidents; Acidosis; Acute Kidney Injury; Bacteremia; Bradycardia; Drug Overdose; Dyslipidemias; For | 2011 |
The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome.
Topics: Adult; Animals; Catecholamines; Central Nervous System; Critical Illness; Drug Interactions; Drug Th | 2003 |
[Propofol infusion syndrome].
Topics: Acid-Base Imbalance; Acidosis, Lactic; Anesthesia, Intravenous; Anesthetics, Intravenous; Chemistry, | 2004 |
Propofol infusion syndrome in anaesthesia and intensive care medicine.
Topics: Acidosis; Anesthesia; Anesthetics, Intravenous; Critical Care; Heart Failure; Humans; Hyperlipidemia | 2006 |
The 'propofol infusion syndrome': the facts, their interpretation and implications for patient care.
Topics: Adolescent; Adult; Anesthesia; Anesthetics, Intravenous; Child; Child, Preschool; Critical Care; Dia | 2006 |
Reports of death with use of propofol (Diprivan) for nonprocedural (long-term) sedation and literature review.
Topics: Acidosis; Adult; Adverse Drug Reaction Reporting Systems; Cardiovascular System; Child; Humans; Hypn | 2006 |
Propofol infusion syndrome.
Topics: Acidosis; Adolescent; Adult; Anesthetics, Intravenous; Biomarkers; Bradycardia; Child; Child, Presch | 2007 |
Too much of a good thing? Tracing the history of the propofol infusion syndrome.
Topics: Accidents, Traffic; Acute Kidney Injury; Adolescent; Adult; Anuria; Brain Injuries; Critical Care; D | 2007 |
Propofol-related infusion syndrome in intensive care patients.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Hypnotics and Sedatives; Infant; Infusio | 2008 |
Propofol infusion syndrome: an overview of a perplexing disease.
Topics: Acidosis; Anesthetics, Intravenous; Arrhythmias, Cardiac; Heart Failure; Hepatomegaly; Humans; Hypno | 2008 |
Propofol infusion syndrome in children.
Topics: Acidosis; Child; Child, Preschool; Female; Heart Diseases; Humans; Hypnotics and Sedatives; Infant; | 1998 |
Propofol toxicity in critically ill pediatric patients: show us the proof.
Topics: Acidosis, Lactic; Anesthetics, Intravenous; Bradycardia; Child; Child, Preschool; Conscious Sedation | 1998 |
Propofol-infusion syndrome in children.
Topics: Adverse Drug Reaction Reporting Systems; Child; Critical Care; Hospital Mortality; Humans; Hypnotics | 1999 |
3 trials available for propofol and Syndrome
| Article | Year |
|---|---|
Biochemical markers in total intravenous anesthesia and propofol infusion syndrome: a preliminary study.
Topics: Adult; Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenou | 2013 |
Effect of Continuous Paravertebral Dexmedetomidine Administration on Intraoperative Anesthetic Drug Requirement and Post-Thoracotomy Pain Syndrome After Thoracotomy: A Randomized Controlled Trial.
Topics: Adjuvants, Anesthesia; Adult; Aged; Amides; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetic | 2017 |
[The tissue oxygen cascade as the marker in different schemes of general anesthesia on dynamics of the hypoxic syndrome in patients, suffering an acute hemorrhage of high operative risk].
Topics: Acute Disease; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Intravenous; Female; Fen | 2008 |
88 other studies available for propofol and Syndrome
| Article | Year |
|---|---|
Anesthesia Procedure for Congenital Insensitivity to Pain in a Child with Anhidrosis Syndrome: A Rare Case.
Topics: Anesthesia; Body Temperature; Calcaneus; Child; Consciousness Monitors; Foot Ulcer; Hereditary Senso | 2017 |
Anesthetic considerations during surgical intervention in Woake's syndrome -a case report.
Topics: Adolescent; Anesthesia, Intravenous; Anesthetics, Intravenous; Ethmoid Sinus; Humans; Infusions, Int | 2019 |
Propofol infusion-like syndrome in a dog.
Topics: Acidosis; Acute Kidney Injury; Animals; Arrhythmias, Cardiac; Dog Diseases; Dogs; Female; Hypnotics | 2018 |
Propofol-related infusion syndrome: role of propofol in medical complications of sedated critical care patients.
Topics: Arrhythmias, Cardiac; Fatal Outcome; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; | 2013 |
Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol.
Topics: Acidosis; Acute Kidney Injury; Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Cohort Studies | 2014 |
Propofol-related infusion syndrome heralding a mitochondrial disease: case report.
Topics: Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Diagnosis, Differential; Fatal Outcome; Femal | 2013 |
Neuroimaging findings in pediatric propofol infusion syndrome.
Topics: Anesthetics, Intravenous; Arteriovenous Malformations; Brain; Child, Preschool; Diffusion Magnetic R | 2014 |
Possible pathogenic mechanism of propofol infusion syndrome involves coenzyme q.
Topics: Anesthetics, Intravenous; Animals; Citric Acid Cycle; Electron Transport; Male; Muscle, Skeletal; Pr | 2015 |
Propofol infusion syndrome: a rare but lethal complication.
Topics: Anesthetics, Intravenous; Critical Care Nursing; Fatal Outcome; Humans; Infusions, Intravenous; Male | 2014 |
Therapeutic plasma exchange as treatment for propofol infusion syndrome.
Topics: Accidents, Traffic; Acidosis, Lactic; Acute Kidney Injury; Adolescent; Anticonvulsants; Biomarkers; | 2015 |
Propofol infusion syndrome: early blood purification to the rescue?
Topics: Anesthetics, Intravenous; Humans; Infusions, Intravenous; Propofol; Propofol Infusion Syndrome; Synd | 2016 |
Predictors of mortality in patients with suspected propofol infusion syndrome.
Topics: Adolescent; Anesthetics, Intravenous; Child; Female; Humans; Logistic Models; Male; Middle Aged; Mor | 2008 |
Tier approach to propofol infusion syndrome.
Topics: Anesthetics, Intravenous; Combined Modality Therapy; Critical Care; Drug Monitoring; Humans; Infusio | 2008 |
Propofol-induced Brugada electrocardiographic pattern.
Topics: Anesthetics, Intravenous; Brugada Syndrome; Critical Care; Drug Monitoring; Electrocardiography; Hum | 2008 |
Early stages of propofol infusion syndrome in paediatric cardiac surgery: two cases in adolescent girls.
Topics: Acidosis, Lactic; Adolescent; Anesthetics, Intravenous; Child; Female; Humans; Hypnotics and Sedativ | 2008 |
Propofol infusion syndrome in adult cardiac surgery.
Topics: Acidosis, Lactic; Aged; Anesthetics, Intravenous; Blood Chemical Analysis; Cardiopulmonary Bypass; C | 2009 |
Self-limited febrile syndromes temporally associated with the use of propofol for sedation in gastrointestinal endoscopic procedures.
Topics: Adverse Drug Reaction Reporting Systems; Chills; Drug Labeling; Endoscopy, Gastrointestinal; Fever; | 2009 |
Predictor of mortality in suspected propofol infusion syndrome--Brugada electrocardiographic pattern.
Topics: Anesthetics, Intravenous; Brugada Syndrome; Hospital Mortality; Humans; Predictive Value of Tests; P | 2009 |
Propofol infusion syndrome in patients with refractory status epilepticus: an 11-year clinical experience.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Critical Illness; Female; Human | 2009 |
Non-acidotic propofol infusion syndrome.
Topics: Adult; Anesthetics, Intravenous; Electrocardiography; Humans; Male; Propofol; Syndrome; Tachycardia, | 2009 |
Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study.
Topics: Academic Medical Centers; Adult; Aged; Anesthetics, Intravenous; Arrhythmias, Cardiac; Critical Illn | 2009 |
Propofol infusion syndrome: difficult to recognize, difficult to study.
Topics: Critical Illness; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Propofol; Syndrome | 2009 |
The propofol infusion syndrome: more puzzling evidence on a complex and poorly characterized disorder.
Topics: Adult; Child; Critical Illness; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Multicenter | 2009 |
Diethylene glycol in propofol infusion syndrome?
Topics: Acidosis; Anesthetics, Intravenous; Drug Contamination; Ethylene Glycols; Humans; Hypnotics and Seda | 2010 |
[General anaesthesia for neurological diseases].
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Autonomic Nervous System; Br | 2010 |
Partial-exchange blood transfusion: an effective method for preventing mortality in a child with propofol infusion syndrome.
Topics: Child, Preschool; Electroencephalography; Exchange Transfusion, Whole Blood; Humans; Hypnotics and S | 2010 |
Propofol Infusion syndrome during refractory status epilepticus in a young adult: successful ECMO resuscitation.
Topics: Adolescent; Extracorporeal Membrane Oxygenation; Female; Humans; Hypnotics and Sedatives; Infusions, | 2011 |
Anesthetic case in a child with congenital neuromuscular disease with uniform type 1 fibers (CNMDU1).
Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Fentanyl; Humans; Hypertensi | 2010 |
Reversible lactic acidosis and electrocardiographic changes in a neurosurgical patient during propofol anesthesia.
Topics: Acidosis, Lactic; Anesthetics, Inhalation; Anesthetics, Intravenous; Arrhythmias, Cardiac; Electroca | 2010 |
Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage.
Topics: Adult; Biomarkers; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lactic Acid; Pro | 2011 |
Propofol infusion syndrome--a critical incident report highlighting the danger of reexposure.
Topics: Adult; Arrhythmias, Cardiac; Head Injuries, Closed; Humans; Hypnotics and Sedatives; Hypotension; In | 2011 |
Propofol infusion syndrome with severe and dynamic Brugada electrocardiogram but benign clinical outcome.
Topics: Brugada Syndrome; Electrocardiography, Ambulatory; Humans; Infusions, Intravenous; Male; Propofol; S | 2011 |
Petty syndrome--implications for anesthesia.
Topics: Abnormalities, Multiple; Androstanols; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous | 2011 |
Inborn oxidative phosphorylation defect as risk factor for propofol infusion syndrome.
Topics: Adult; Anesthetics, Intravenous; Humans; Infusions, Intravenous; Male; Muscle, Skeletal; Optic Atrop | 2012 |
Propofol infusion syndrome: an algorithm for prevention.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2011 |
Propofol-related infusion syndrome induced by "moderate dosage" in a patient with severe head trauma.
Topics: Acidosis; Adult; Anesthetics, Intravenous; Craniocerebral Trauma; Dose-Response Relationship, Drug; | 2012 |
Propofol infusion syndrome heralded by ECG changes.
Topics: Acidosis; Brain Injuries; Electrocardiography; Humans; Hypnotics and Sedatives; Intracranial Hyperte | 2012 |
Propofol syndrome in children.
Topics: Acidosis; Age Factors; Anesthetics, Intravenous; Child; Conscious Sedation; Critical Illness; Hepato | 2003 |
Propofol syndrome in children.
Topics: Age Factors; Anesthetics, Intravenous; Child; Child, Preschool; Conscious Sedation; Contraindication | 2003 |
Comment: propofol infusion syndrome in critically ill patients.
Topics: Adult; Anesthetics, Intravenous; Child; Critical Illness; Humans; Injections, Intravenous; Propofol; | 2003 |
Propofol infusion syndrome--report of an adult fatality.
Topics: Adult; Electrocardiography; Fatal Outcome; Head Injuries, Closed; Humans; Hypnotics and Sedatives; I | 2003 |
Anaesthetic implications of Robinow syndrome.
Topics: Abnormalities, Multiple; Androstanols; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, In | 2003 |
Anaesthesia in a child with Sotos syndrome.
Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Atrop | 2003 |
Lactic acidosis: an early marker of propofol infusion syndrome?
Topics: Acidosis, Lactic; Anesthetics, Intravenous; Child, Preschool; Female; Humans; Propofol; Syndrome | 2004 |
Death after re-exposure to propofol in a 3-year-old child: a case report.
Topics: Acidosis; Child, Preschool; Drug Overdose; Fatal Outcome; Female; Humans; Hypnotics and Sedatives; P | 2004 |
[Anesthetic management for a patient with platypnea-orthodeoxia syndrome].
Topics: Aged; Anesthesia, General; Dyspnea; Fentanyl; Heart Septal Defects, Atrial; Humans; Hypoxia; Male; M | 2004 |
Propofol infusion in children: when does an anesthetic tool become an intensive care liability?
Topics: Acetylcarnitine; Adult; Biomarkers; Child; Conscious Sedation; Critical Care; Fatty Acids; Humans; H | 2004 |
A case of propofol toxicity: further evidence for a causal mechanism.
Topics: Acidosis; Acute Kidney Injury; Arrhythmias, Cardiac; Cleft Lip; Conscious Sedation; Humans; Hypnotic | 2004 |
Fatal propofol infusion syndrome in association with ketogenic diet.
Topics: Acidosis; Anticonvulsants; Child; Diet Therapy; Fatal Outcome; Humans; Infusions, Parenteral; Male; | 2004 |
Anesthetic management in Joubert syndrome.
Topics: Agenesis of Corpus Callosum; Anesthesia; Anesthesia, Caudal; Apnea; Ataxia; Brain; Corpus Callosum; | 2004 |
Propofol infusion syndrome: an unusual cause of renal failure.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Adult; Craniocerebral Trauma; Female; Humans; Infusions, | 2004 |
Rare but dangerous adverse effects of propofol and thiopental in intensive care.
Topics: Acidosis; Adult; Anesthetics, Intravenous; Coma; Conscious Sedation; Critical Care; Fatal Outcome; F | 2005 |
Acquired carnitine deficiency: a clinical model for propofol infusion syndrome?
Topics: Adult; Anesthetics, Intravenous; Carnitine; Fatty Acids; Humans; Mitochondria; Oxidation-Reduction; | 2005 |
[Anaesthesia for nuclear magnetic imaging in a child with DRESS syndrome].
Topics: Anesthesia, General; Anesthetics, Intravenous; Child, Preschool; Drug Eruptions; Eosinophilia; Epile | 2006 |
The syndrome of irreversible acidosis after prolonged propofol infusion.
Topics: Acidosis; Adult; Anesthetics, Intravenous; Fatal Outcome; Female; Humans; Infusions, Intravenous; Ma | 2005 |
Toward a prediction of sudden death in propofol-related infusion syndrome.
Topics: Acidosis; Acute Kidney Injury; Death, Sudden, Cardiac; Electrocardiography; Humans; Hypnotics and Se | 2006 |
Electrocardiographic changes predicting sudden death in propofol-related infusion syndrome.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Death, Sudden, Cardiac; Electrocardiography; Humans; Hypn | 2006 |
A case of suspected non-neurosurgical adult fatal propofol infusion syndrome.
Topics: Adolescent; Anesthetics, Intravenous; Fatal Outcome; Female; Humans; Hypnotics and Sedatives; Infusi | 2006 |
Myoglobinemia and propofol infusion.
Topics: Anesthetics, Intravenous; Humans; Myoglobin; Propofol; Rhabdomyolysis; Syndrome | 2006 |
Propofol infusion syndrome during anaesthesia for scoliosis surgery in an adolescent with neonatal progeroid syndrome.
Topics: Acidosis; Adolescent; Anesthetics, Intravenous; Arrhythmias, Cardiac; Female; Humans; Progeria; Prop | 2006 |
Central anticholinergic syndrome strikes again.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, General; Anesthetics, Intravenous; Central Nervous System | 2006 |
[Propofol infusion syndrome].
Topics: Acidosis; Acute Kidney Injury; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Arrhythmias, | 2006 |
Anesthesia management for the child with Sanjad-Sakati syndrome.
Topics: Abnormalities, Multiple; Anesthesia, Dental; Anesthetics, Inhalation; Anesthetics, Intravenous; Anes | 2006 |
Propofol infusion syndrome in a patient with sepsis.
Topics: Abdominal Abscess; Acidosis; Adult; Anesthetics, Intravenous; Drainage; Heart Failure; Humans; Hyper | 2006 |
The 'propofol infusion syndrome': myth or menace?
Topics: Acidosis; Anesthesia; Anesthetics, Intravenous; Critical Care; Diagnosis, Differential; Humans; Hypo | 2006 |
Propofol infusion syndrome: a case of increasing morbidity with traumatic brain injury.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Anesthetics, Intravenous; Brain Injuries; Fatal Outcome; | 2007 |
[Anesthesia in May-Hegglin anomaly].
Topics: Adenocarcinoma; Anesthesia, Intravenous; Anesthetics, Intravenous; Anticoagulants; Aprotinin; Bernar | 2006 |
Early propofol infusion syndrome following cerebral angiographic embolization for giant aneurysm repair. Case report.
Topics: Acidosis; Anesthetics, Intravenous; Aneurysm; Balloon Occlusion; Cardiac Output, Low; Carotid Artery | 2007 |
Propofol-associated fatal myocardial failure and rhabdomyolysis in an adult with status epilepticus.
Topics: Acidosis; Adult; Age Factors; Anticonvulsants; Cardiac Output, Low; Cardiomyopathies; Fatal Outcome; | 2007 |
The propofol infusion syndrome treated with haemofiltration. Is there a time for genetic screening?
Topics: Adult; Anesthesia, Intravenous; Craniocerebral Trauma; Female; Genetic Testing; Hemofiltration; Huma | 2007 |
Anaesthesia and Alström's syndrome.
Topics: Adult; Anesthesia; Anesthetics, Intravenous; Atrial Fibrillation; Blindness; Deafness; Diabetes Mell | 2007 |
Antimuscarinic syndrome after propofol administration in the emergency department.
Topics: Adult; Diagnosis, Differential; Drug Interactions; Emergency Service, Hospital; Humans; Hypnotics an | 2007 |
Propofol infusion syndrome or probable overinterpretation syndrome?
Topics: Acidosis, Lactic; Anesthetics, Intravenous; Cohort Studies; Humans; Infusions, Intravenous; Propofol | 2008 |
A national survey of propofol infusion use by paediatric anaesthetists in Great Britain and Ireland.
Topics: Anesthesiology; Anesthetics, Intravenous; Electroencephalography; Health Care Surveys; Humans; Infus | 2008 |
Anesthesia for orthopedic surgery in Pallister-Killian syndrome.
Topics: Abnormalities, Multiple; Alfentanil; Androstanols; Anesthesia; Anesthesia, Epidural; Anesthetics, Co | 2008 |
Anaesthetic management of a child with Freeman-sheldon syndrome undergoing spinal surgery.
Topics: Abnormalities, Multiple; Anesthesia, General; Anesthetics, Intravenous; Arthrogryposis; Blood Pressu | 2008 |
Propofol for the management of glycine-mediated excitatory symptoms of TURP syndrome.
Topics: Aged; Akathisia, Drug-Induced; Glycine; Glycine Agents; Humans; Hyperammonemia; Hypnotics and Sedati | 2008 |
Suggested beginning of propofol infusion syndrome in an adult patient without lactacidosis: a case report.
Topics: Acidosis, Lactic; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Brain Diseases; Creatine | 2008 |
Sudden unexpected sneezing during the insertion of peribulbar block under propofol sedation.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Genes, Dominant; Humans; Lidocaine | 1995 |
Anaesthesia for Mauriac's syndrome.
Topics: Adolescent; Anesthesia, General; Corneal Transplantation; Diabetes Mellitus; Diabetes Mellitus, Type | 1993 |
Propofol-infusion syndrome in children.
Topics: Child; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Propofol; Syndrome | 1999 |
Anaesthetic implications of rigid spine syndrome.
Topics: Adolescent; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Contracture; Fem | 1999 |
[Anesthetic management of a patient with Coffin-Lowry syndrome].
Topics: Abnormalities, Multiple; Adult; Anesthesia, General; Anesthetics, Intravenous; Craniofacial Abnormal | 1999 |
[A case of hyperperfusion syndrome treated successfully by propofol].
Topics: Aged; Anesthesia, Intravenous; Carotid Stenosis; Cerebrovascular Circulation; Cerebrovascular Disord | 2001 |
Impaired fatty acid oxidation in propofol infusion syndrome.
Topics: Acidosis; Carnitine; Critical Care; Electron Transport; Fatty Acids; Hemofiltration; Humans; Hypnoti | 2001 |
Propofol use in head-injury patients.
Topics: Acidosis; Adolescent; Adult; Anesthetics, Intravenous; Animals; Cardiac Output; Craniocerebral Traum | 2001 |
Propofol.
Topics: Adolescent; Heart Failure; Humans; Infusions, Intravenous; Male; Propofol; Renal Insufficiency; Rhab | 2002 |
Propofol.
Topics: Adult; Heart Failure; Humans; Infusions, Intravenous; Male; Propofol; Renal Insufficiency; Rhabdomyo | 2002 |